Study Publications for ROS

Overview of Cohort — Religious Orders Study (ROS)

Religious Orders Study and Rush Memory and Aging Project
Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA.
J Alzheimers Dis. 64(s1):S161-S189. PubMed PMID: 29865057
Published date: 2018 Jun 12

Overview and findings from the religious orders study.
Bennett DA, Schneider JA, Arvanitakis Z, Wilson RS.
Curr Alzheimer Res. 9(6):628-45. PubMed PMID: 22471860
Published date: 2012 Jul;


Other Publications

Association between hippocampal microglia, AD and LATE-NC, and cognitive decline in older adults.
Kapasi A, Yu L, Leurgans SE, Agrawal S, Boyle PA, Bennett DA, Schneider JA
Alzheimer's & dementia : the journal of the Alzheimer's Association. PubMed PMID: 38494787
Published date: 2024 Mar 17
APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response.
Panitch R, Sahelijo N, Hu J, Nho K, Bennett DA, Lunetta KL, Au R, Stein TD, Farrer LA, Jun GR
Translational psychiatry 14 (1):129. PubMed PMID: 38424036
Published date: 2024 Feb 29
Associations of 24-Hour Rest-Activity Rhythm Fragmentation, Cognitive Decline, and Postmortem Locus Coeruleus Hypopigmentation in Alzheimer's Disease.
Van Egroo M, van Someren EJW, Grinberg LT, Bennett DA, Jacobs HIL
Annals of neurology. PubMed PMID: 38407546
Published date: 2024 Feb 26
Associations of Serum Insulin and Related Measures With Neuropathology and Cognition in Older Persons With and Without Diabetes.
Arvanitakis Z, Capuano AW, Tong H, Mehta RI, Anokye-Danso F, Bennett DA, Arnold SE, Ahima RS
Annals of neurology. PubMed PMID: 38379184
Published date: 2024 Feb 20
Changes in an in-vivo classifier of ARTerioloSclerosis (ARTS) with simultaneous change in cognition for older African Americans.
Lamar M, Arfanakis K, Evia A, Makkinejad N, Capuano AW, Kim N, Leurgans SE, Fleischman DA, Duke Han S, Poole V, Barnes LL
Neurobiology of aging. PubMed PMID: 37979249
Published date: 2024 Feb
Sex-specific genetic architecture of late-life memory performance.
Eissman JM, Archer DB, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Mayeux RP, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Hohman TJ, Dumitrescu L
Alzheimer's & dementia : the journal of the Alzheimer's Association 20 (2):-1267. PubMed PMID: 37984853
Published date: 2024 Feb
Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease.
Archer DB, Eissman JM, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Gifford KA, Cuccaro ML, Pericak-Vance MA, Farrer LA, Wang LS, Schellenberg GD, Mayeux RP, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Dumitrescu L, Hohman TJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 20 (2):1268-1283. PubMed PMID: 37985223
Published date: 2024 Feb
Identification of Dementia in Medicare Claims Compared to Rigorous Clinical Assessments in African Americans.
Grodstein F, James BD, Chen Y, Capuano AW, Power MC, Bennett DA, Bynum JPW, Barnes LL
The journals of gerontology. Series A, Biological sciences and medical sciences. PubMed PMID: 37776149
Published date: 2024 Jan 01
INPP5D regulates inflammasome activation in human microglia.
Chou V, Pearse RV, Aylward AJ, Ashour N, Taga M, Terzioglu G, Fujita M, Fancher SB, Sigalov A, Benoit CR, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, Menon V, Young-Pearse TL
Nature communications 14 (1):7552. PubMed PMID: 38016942
Published date: 2023 Nov 29
Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta-analysis.
Beck ED, Yoneda T, James BD, Bennett DA, Hassenstab J, Katz MJ, Lipton RB, Morris J, Mroczek DK, Graham EK
Alzheimer's & dementia : the journal of the Alzheimer's Association 20 (3):1497-1514. PubMed PMID: 38018701
Published date: 2023 Nov 29
Brain Insulin Signaling is Associated with Late-Life Cognitive Decline.
Tong H, Capuano AW, Carmichael OT, Gwizdala KL, Bennett DA, Ahima RS, Arnold SE, Arvanitakis Z
Aging and disease. PubMed PMID: 38029396
Published date: 2023 Nov 20
miR-129-5p as a biomarker for pathology and cognitive decline in Alzheimer's disease.
Han SW, Pyun JM, Bice PJ, Bennett DA, Saykin AJ, Kim S, Park YH, Nho K
Research square. PubMed PMID: 37961387
Published date: 2023 Nov 01
A public resource of single cell transcriptomes and multiscale networks from persons with and without Alzheimer's disease.
Wang Q, Antone J, Alsop E, Reiman R, Funk C, Bendl J, Dudley JT, Liang WS, Karr TL, Roussos P, Bennett DA, De Jage r PL, Serrano GE, Beach TG, Keuren-Jensen KV, Mastroeni D, Reiman EM, Readhead BP
bioRxiv : the preprint server for biology. PubMed PMID: 37961404
Published date: 2023 Oct 24
Relation of Motor Impairments to Neuropathologic Changes of Limbic-Predominant Age-Related TDP-43 Encephalopathy in Older Adults.
Oveisgharan S, Yu L, Agrawal S, Nag S, Bennett DA, Buchman AS, Schneider JA
Neurology 101 (15):e1542-e1553. PubMed PMID: 37604667
Published date: 2023 Oct 10
Author Response: Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
Oveisgharan S, Bennett DA
Neurology 101 (14):634. PubMed PMID: 37783504
Published date: 20 23 Oct 03
Differential gene expression analysis based on linear mixed model corrects false positive inflation for studying quantitative traits.
Tang S, Buchman AS, Wang Y, Avey D, Xu J, Tasaki S, Bennett DA, Zheng Q, Yang J
Scientific reports 13 (1):16570. PubMed PMID: 37789141
Published date: 2023 Oct 03
High resolution 0.5mm isotropic T1-weighted and diffusion tensor templates of the brain of non-demented older adults in a common space for the MIITRA atlas.
Wu Y, Ridwan AR, Niaz MR, Bennett DA, Arfanakis K
NeuroImage. PubMed PMID: 37783362
Published date: 2023 Oct 01
Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology.
Mathys H, Peng Z, Boix CA, Victor MB, Leary N, Babu S, Abdelhady G, Jiang X, Ng AP, Ghafari K, Kunisky AK, Mantero J, Galani K, Lohia VN, Fortier GE, Lotfi Y, Ivey J, Brown HP, Patel PR, Chakraborty N, Beaudway JI, Imhoff EJ, Keeler CF, McChesney MM, Patel HH, Patel SP, Thai MT, Bennett DA, Kellis M, Tsai LH
Cell 186 (20):4365-4385.e27. PubMed PMID: 37774677
Published date: 2023 Sep 28
Human microglial state dynamics in Alzheimer's disease progression.
Sun N, Victor MB, Park YP, Xiong X, Scannail AN, Leary N, Prosper S, Viswanathan S, Luna X, Boix CA, James BT, Tanigawa Y, Galani K, Mathys H, Jiang X, Ng AP, Benne tt DA, Tsai LH, Kellis M
Cell 186 (20):4386-4403.e29. PubMed PMID: 37774678
Published date: 2023 Sep 28
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.
Dileep V, Boix CA, Mathys H, Marco A, Welch GM, Meharena HS, Loon A, Jeloka R, Peng Z, Bennett DA, Kellis M, Tsai LH
Cell 186 (20):4404-4421.e20. PubMed PMID: 37774679
Published date: 2023 Sep 28
Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion.
Xiong X, James BT, Boix CA, Park YP, Galani K, Victor MB, Sun N, Hou L, Ho LL, Mantero J, Scannail AN, Dileep V, Dong W, Mathys H, Bennett DA, Tsai LH, Kellis M
Cell 186 (20):4422-4437.e21. PubMed PMID: 37774680
Published date: 2023 Sep 28
Associations of cortical SPP1 and ITGAX with cognition and common neuropathologies in older adults.
Lopes KP, Yu L, Shen X, Qiu Y, Tasaki S, Iatrou A, Beeri MS, Seyfried NT, Menon V, Wang Y, Schneider JA, Cantor H, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 20 (1):525-537. PubMed PMID: 37727065
Published date: 2023 Sep 19
Knockout of the longevity gene Klotho perturbs aging- and Alzheimer's disease-linked brain microRNAs and tRNA fragments.
Dubnov S, Yayon N, Yakov O, Ben nett DA, Seshadri S, Mufson E, Tzur Y, Bennet ER, Greenberg D, Kuro-O M, Paldor I, Abraham CR, Soreq H
bioRxiv : the preprint server for biology. PubMed PMID: 37745362
Published date: 2023 Sep 12
Acculturation in Context and Brain Health in Older Latino Adults: A Diffusion Tensor Imaging Study.
Fleischman DA, Arfanakis K, Zhang S, Leurgans SE, Barnes LL, Bennett DA, Marquez DX, Lamar M
Journal of Alzheimer's disease : JAD 95 (4):1585-1595. PubMed PMID: 37718813
Published date: 2023 Sep 11
Selective serotonin reuptake inhibitor use, age-related neuropathology and cognition in late-life.
Sood A, Wilson RS, Yu L, Wang T, Schneider JA, Honer WG, Bennett DA
Psychiatry research. PubMed PMID: 37742529
Published date: 2023 Sep 09
Evaluating genomic signatures of aging in brain tissue as it relates to Alzheimer's disease.
Lynch MT, Taub MA, Farfel JM, Yang J, Abadir P, De Jager PL, Grodstein F, Bennett DA, Mathias RA
Scientific reports 13 (1):14747. PubMed PMID: 37679407
Published date: 2023 Sep 07
Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
Higginbotham L, Carter EK, Dammer EB, Haque RU, Johnson ECB, Duong DM, Yin L, De Jager PL, Bennett DA, Felsky D, Tio ES, Lah JJ, Levey AI, Seyfried NT
Neurobiology of disease. PubMed PMID: 37689213
Published date: 2023 Sep 07
Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults.
Walters S, Contreras AG, Eissman JM, Mukherjee S, Lee ML, Choi SE, Scollard P, Trittschuh EH, Mez JB, Bush WS, Kunkle BW, Naj AC, Peterson A, Gifford KA, Cuccaro ML, Cruchaga C, Pericak-Vance MA, Farrer LA, Wang LS, Haines JL, Jefferson AL, Kukull WA, Keene CD, Saykin AJ, Thompson PM, Martin ER, Bennett DA, Barnes LL, Schneider JA, Crane PK, Hohman TJ, Dumitrescu L
JAMA neurology 80 (9):929-939. PubMed PMID: 37459083
Published date: 2023 Sep 01
Neuropathologic correlates of cerebral microbleeds in community-based older adults.
Nikseresht G, Evia AM, Nag S, Leurgans SE, Capuano AW, Agam G, Barnes LL, Bennett DA, Schneider JA, Arfanakis K
Neurobiology of aging. PubMed PMID: 37279617
Published date: 2023 Sep
Explainable deep learning approach for extracting cognitive features from hand-drawn images of intersecting pentagons.
Tasaki S, Kim N, Truty T, Zhang A, Buchman AS, Lamar M, Bennett DA
NPJ digital medicine 6 (1):157. PubMed PMID: 37612472
Published date: 2023 Aug 23
Effects of Cerebrovascular and Lewy Body Pathology on Parkinsonian Signs in Community-Dwelling Older Adults.
Agrawal S, Leurgans SE, Nag S, Oveisgharan S, Barnes LL, Bennett DA, Buchman AS, Schneider JA
Neurology 101 (7):e754-e763. PubMed PMID: 37438127
Published date: 2023 Aug 15
Transcriptional risk scores in Alzheimer's disease: From pathology to cognition.
Pyun JM, Park YH, Wang J, Bennett DA, Bice PJ, Kim JP, Kim S, Saykin AJ, Nho K
Alzheimer's & dementia : the journal of the Alzheimer's Association 20 (1):243-252. PubMed PMID: 37563770
Published date: 2023 Aug 10
LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry.
Katsumata Y, Fardo DW, Shade LMP, Nelson PT
Journal of neuropathology and experimental neurology 82 (9):760-768. PubMed PMID: 37528055
Published date: 2023 Aug 01
Neuronal actin cytoskeleton gain of function in the human brain.
Szigeti K, Ihnatovych I, Rosas N, Dorn RP, Notari E, Cortes Gomez E, He M, Maly I, Prasad S, Nimmer E, Heo Y, Fuchsova B, Bennett DA, Hofmann WA, Pralle A, Bae Y, Wang J
EBioMedicine 95 (14):104725. PubMed PMID: 37517100
Published date: 2023 Jul 28
A Molecular Basis of Human Brain Connectivity.
Ng B, Tasaki S, Greathouse KM, Walker CK, Zhang A, Covitz S, Cieslak M, Adamson AB, Andrade JP, Poovey EH, Curtis KA, Muhammad HM, Seidlitz J, Satterthwaite T, Bennett DA, Seyfried NT, Vogel J, Gaiteri C, Herskowitz JH
bioRxiv : the preprint server for biology. PubMed PMID: 37546752
Published date: 2023 Jul 24
Primacy and recency effects in verbal memory are differentially associated with post-mortem frontal cortex p-tau 217 and 202 levels in a mixed sample of community-dwelling older adults.
Gicas KM, Honer WG, Petyuk VA, Wilson RS, Boyle PA, Leurgans SE, Schneider JA, De Jager PL, Bennett DA
Journal of clinical and experimental neuropsychology 45 (8):1-16. PubMed PMID: 37440260
Published date: 2023 Jul 13
Testing a Polygenic Risk Score for Morphological Microglial Activation in Alzheimer's Disease and Aging.
Tio ES, Hohman TJ, Milic M, Bennett DA, Felsky D
Journal of Alzheimer's disease : JAD 94 (4):1549-1561. PubMed PMID: 37458040
Published date: 2023 Jul 10
SR-TWAS: Leveraging Multiple Reference Panels to Improve TWAS Power by Ensemble Machine Learning.
Parrish RL, Buchman AS, Tasaki S, Wang Y, Avey D, Xu J, De Jager PL, Bennett DA, Epstein MP, Yang J
medRxiv : the preprint server for health sciences. PubMed PMID: 37425698
Published date: 2023 Jun 27
Multicellular communities are perturbed in the aging human brain and Alzheimer's disease.
Cain A, Taga M, McCabe C, Green GS, Hekselman I, White CC, Lee DI, Gaur P, Rozenblatt-Rosen O, Zhang F, Yeger-Lot em E, Bennett DA, Yang HS, Regev A, Menon V, Habib N, De Jager PL
Nature neuroscience 26 (7):1267-1280. PubMed PMID: 37336975
Published date: 2023 Jun 19
Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias.
Kaivola K, Chia R, Ding J, Rasheed M, Fujita M, Menon V, Walton RL, Collins RL, Billingsley K, Brand H, Talkowski M, Zhao X, Dewan R, Stark A, Ray A, Solaiman S, Alvare z Jerez P, Malik L, Dawson TM, Rosenthal LS, Albert MS, Pletnikova O, Troncoso JC, Masellis M, Keith J, Black SE, Ferrucci L, Resnick SM, Tanaka T, Topol E, Torkamani A, Tienari P, Foroud TM, Ghetti B, Landers JE, Ryten M, Morris HR, Hardy JA, Mazzini L, D'Alfonso S, Moglia C, Calvo A, Serrano GE, Beach TG, Ferman T, Graff-Radford NR, Boeve BF, Wszolek ZK, Dickson DW, Chi A, Bennett DA, De Jager PL, Ross OA, Dalgard CL, Gibbs JR, Traynor BJ, Scholz SW
Cell genomics 3 (6):100316. PubMed PMID: 37388914
Published date: 2023 Jun 14
Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease.
Yang HS, Teng L, Kang D, Menon V, Ge T, Finucane HK, Schultz AP, Properzi M, Klein HU, Chibnik LB, Schneider JA, Bennett DA, Hohman TJ, Mayeux RP, Johnson KA, De Jager PL, Sperling RA
medRxiv : the preprint server for health sciences. PubMed PMID: 37333223
Published date: 2023 Jun 05
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer's disease.
Sun N, Akay LA, Murdock MH, Park Y, Galiana-Melendez F, Bubnys A, Galani K, Mathys H, Jiang X, Ng AP, Bennett DA, Tsai LH, Kellis M
Nature neuroscience 26 (6):970-982. PubMed PMID: 37264161
Published date: 2023 Jun
Postsynaptic protein Shank3a deficiency synergizes with Alzheimer's disease neuropathology to impair cognitive performance in the 3xTg-AD murine model.
Landry O, Fran ois A, Oye Mintsa Mi-Mba MF, Traversy MT, Tremblay C, Emond V, Bennett DA, Gylys KH, Buxbaum JD, Calon F
The Journal of neuroscience : the official journal of the Society for Neuroscience 43 (26):4941-4954. PubMed PMID: 37253603
Published date: 2023 May 30
Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer's disease.
Merchant JP, Zhu K, Henrion MYR, Zaidi SSA, Lau B, Moein S, Alamprese ML, Pearse RV, Bennett DA, Ertekin-Taner N, Young-Pearse TL, Chang R
Communications biology 6 (1):503. PubMed PMID: 37188718
Published date: 2023 May 15
The associations of VGF with neuropathologies and cognitive health in older adults.
Yu L, Petyuk VA, Lopes KP, Tasaki S, Menon V, Wang Y, Schneider JA, De Jager PL, Bennett DA
Annals of neurology 94 (2):232-244. PubMed PMID: 37177846
Published date: 2023 May 13
Cognitive domain harmonization and cocalibration in studies of older adults.
Mukherjee S, Choi SE, Lee ML, Scollard P, Trittschuh EH, Mez J, Saykin AJ, Gibbons LE, Sanders RE, Zaman AF, Teylan MA, Kukull WA, Barnes LL, Bennett DA, Lacroix AZ, Larson EB, Cuccaro M, Mercado S, Dumitrescu L, Hohman TJ, Crane PK
Neuropsychology 37 (4):409-423. PubMed PMID: 35925737
Published date: 2023 May
Ancestry-related differences in chromatin accessibility and gene expression of APOE 4 are associated with Alzheimer's disease risk.
Celis K, Moreno MDMM, Rajabli F, Whitehead P, Hamilton-Nelson K, Dykxhoorn DM, Nuytemans K, Wang L, Flanagan M, Weintraub S, Geula C, Gearing M, Dalgard CL, Jin F, Bennett DA, Schuck T, Pericak-Vance MA, Griswold AJ, Young JI, Vance JM
Alzheimer's & dementia : the journal of the Alzheimer's Association 19 (9):3902-3915. PubMed PMID: 37037656
Published date: 2023 Apr 10
Plasma p-tau181 and p-tau217 in discriminating PART, AD and other key neuropathologies in older adults.
Yu L, Boyle PA, Janelidze S, Petyuk VA, Wang T, Bennett DA, Hansson O, Schneider JA
Acta neuropathologica 146 (1):1-11. PubMed PMID: 37031430
Published date: 2023 Apr 09
Integrated Proteomics to Understand the Role of Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease.
Hurst C, Pugh DA, Abreha MH, Duong DM, Dammer EB, Bennett DA, Herskowitz JH, Seyfried NT
Molecular & cellular proteomics : MCP 22 (5):100542. PubMed PMID: 37024090
Published date: 2023 Apr 04
Stability and change in acculturation-related characteristics in older Latinos: Implications for culturally compatible ADRD research.
Lamar M, Glover CM, Capuano AW, Wilson RS, Fleischman DA, Bennett DA, Marquez DX
Alzheimer's & dementia (New York, N. Y.) 9 (2):e12380. PubMed PMID: 37051589
Published date: 2023 Apr-Jun
Classification statistics of the Montreal Cognitive Assessment (MoCA): Are we interpreting the MoCA correctly?
Ratcliffe LN, McDonald T, Robinson B, Sass JR, Loring DW, Hewitt KC
The Clinical neuropsychologist 37 (3):-576. PubMed PMID: 35699222
Published date: 2023 Apr
A single-nucleus transcriptome-wide association study implicates novel genes in depression pathogenesis.
Zeng L, Fujita M, Gao Z, White CC, Green GS, Habib N, Menon V, Bennett DA, Boyle PA, Klein HU, De Jager PL
medRxiv : the preprint server for health sciences. PubMed PMID: 37034737
Published date: 2023 Mar 29
Oligomeric, phosphorylated, and truncated tau and spliceosome pathology within the entorhinal-hippocampal connectome across stages of Alzheimer's disease.
Mahady LJ, Perez SE, Malek-Ahmadi M, Mufson EJ
The Journal of comparative neurology 531 (18):2080-2108. PubMed PMID: 36989381
Published date: 2023 Mar 29
TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.
Winfree RL, Seto M, Dumitrescu L, Menon V, De Jager P, Wang Y, Schneider J, Bennett DA, Jefferson AL, Hohman TJ
Acta neuropathologica 145 (6):733-747. PubMed PMID: 36966244
Published date: 2023 Mar 25
A Longitudinal Study of Acculturation in Context and Cardiovascular Health and Their Effects on Cognition Among Older Latino Adults.
Lamar M, Estrella ML, Capuano AW, Leurgans S, Fleischman DA, Barnes LL, Lange-Maia BS, Bennett DA, Marquez DX
Journal of the American Heart Association 12 (6):7620. PubMed PMID: 36926993
Published date: 2023 Mar 21
ZCCHC17 modulates neuronal RNA splicing and supports cognitive resilience in Alzheimer's disease.
Bartosch AMW, Youth EHH, Hansen S, Kaufman ME, Xiao H, Koo SY, Ashok A, Sivakumar S, Soni RK, Dumitrescu LC, Lam TG, Ropri AS, Lee AJ, Klein HU, Vardarajan BN, Bennett DA, Young-Pearse TL, De Jager PL, Hohman TJ, Sproul AA, Teich AF
bioRxiv : the preprint server for biology. PubMed PMID: 36993746
Published date: 2023 Mar 21
How far are we from personalized gene expression prediction using sequence-to-expression deep neural networks?
Sasse A, Ng B, Spiro A, Tasaki S, Bennett DA, Gaiteri C, De Jager PL, Chikina M, Mostafavi S
bioRxiv : the preprint server for biology. PubMed PMID: 36993652
Published date: 2023 Mar 20
Testing a polygenic risk score for morphological microglial activation in Alzheimer's disease and aging.
Tio ES, Hohman TJ, Mil ic M, Bennett DA, Felsky D
medRxiv : the preprint server for health sciences. PubMed PMID: 36993775
Published date: 2023 Mar 15
INPP5D/SHIP1 regulates inflammasome activation in human microglia.
Chou V, Fancher SB, Pearse RV, Lee H, Lam M, Seyfried NT, Bennett DA, De Jager PL, Menon V, Young-Pearse TL
bioRxiv : the preprint server for biology. PubMed PMID: 36865139
Published date: 2023 Feb 26
Cell-type-specific regulation of APOE levels in human neurons by the Alzheimer's disease risk gene SORL1.
Lee H, Aylward AJ, Pearse RV, Hsieh YC, Augur ZM, Benoit CR, Chou V, Knupp A, Pan C, Goberdhan S, Duong DM, Seyfried NT, Bennett DA, Klein HU, De Jager PL, Menon V, You ng JE, Young-Pearse TL
bioRxiv : the preprint server for biology. PubMed PMID: 36865313
Published date: 2023 Feb 25
Racial and ethnic differences in neuropsychiatric symptoms and progression to incident cognitive impairment among community-dwelling participants.
Babulal GM, Zhu Y, Trani JF
Alzheimer's & dementia : the journal of the Alzheimer's Association 19 (8):3635-3643. PubMed PMID: 36840665
Published date: 2023 Feb 25
Predicting age at Alzheimer's dementia onset with the cognitive clock.
Yu L, Wang T, Wilson RS, Guo W, Aggarwal NT, Bennett DA, Boyle PA
Alzheimer's & dementia : the journal of the Alzheimer's Association 19 (8):3555-3562. PubMed PMID: 36825796
Published date: 2023 Feb 24
Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease.
Wang E, Wang M, Guo L, Fullard JF, Micallef C, Bendl J, Song WM, Ming C, Huang Y, Li Y, Yu K, Peng J, Bennett DA, De Jager PL, Roussos P, Haroutunian V, Zhang B
Alzheimer's & dementia : the journal of the Alzheimer's Association 19 (8):3472-3495. PubMed PMID: 36811307
Published date: 2023 Feb 22
The status of digital pathology and associated infrastructure within Alzheimer's Disease Centers.
Scalco R, Hamsafar Y, White CL, Schneider JA, Reichard RR, Prokop S, Perrin RJ, Nelson PT, Mooney S, Lieberman AP, Kukull WA, Kofler J, Keene CD, Kapasi A, Irwin DJ, Gutman DA, Flanagan ME, Crary JF, Chan KC, Murray ME, Dugger BN
Journal of neuropathology and experimental neurology 82 (3):202-211. PubMed PMID: 36692179
Published date: 2023 Feb 21
Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease.
Shulman D, Dubnov S, Zorbaz T, Madrer N, Paldor I, Bennett DA, Seshadri S, Mufson EJ, Greenberg DS, Loewenstein Y, Soreq H
bioRxiv : the preprint server for biology. PubMed PMID: 36798311
Published date: 2023 Feb 20
Trends in Postmortem Neurodegenerative and Cerebrovascular Neuropathologies Over 25 Years.
Grodstein F, Leurgans SE, Capuano AW, Schneider JA, Bennett DA
JAMA neurology 80 (4):370-376. PubMed PMID: 36805154
Published date: 2023 Feb 20
Associations between loneliness and cognitive resilience to neuropathology in older adults.
Jackson KL, Luo J, Willroth EC, Ong AD, James BD, Bennett DA, Wilson R, Mroczek DK, Graham EK
The journals of gerontology. Series B, Psychological sciences and social sciences 78 (6):939-947. PubMed PMID: 36789449
Published date: 2023 Feb 15
Somatic nuclear mitochondrial DNA insertions are prevalent in the human brain and accumulate in aging fibroblasts.
Zhou W, Karan KR, Klein HU, Sturm G, De Jager PL, Bennett DA, Hirano M, Picard M, Mills RE
bioRxiv : the preprint server for biology. PubMed PMID: 36778249
Published date: 2023 Feb 04
Opioid medication use and blood DNA methylation: epigenome-wide association meta-analysis.
Lee M, Joehanes R, McCartney DL, Kho M, H ls A, Wyss AB, Liu C, Walker RM, R Kardia SL, Wingo TS, Burkholder A, Ma J, Campbell A, Wingo AP, Huan T, Sikdar S, Keshawarz A, Bennett DA, Smith JA, Evans KL, Levy D, London SJ
Epigenomics 14 (23):1479-1492. PubMed PMID: 36700736
Published date: 2023 Jan 26
Estrogen Receptor Genes, Cognitive Decline, and Alzheimer Disease.
Oveisgharan S, Yang J, Yu L, Burba D, Bang W, Tasaki S, Grodstein F, Wang Y, Zhao J, De Jager PL, Schneider JA, Bennett DA
Neurology 100 (14):e1474-e1487. PubMed PMID: 36697247
Published date: 2023 Jan 25
Blood pressure variability, dementia, and role of antihypertensive medications in older adults.
Mahinrad S, Bennett DA, Sorond FA, Gorelick PB
Alzheimer's & dementia : the journal of the Alzheimer's Association 19 (7):2966-2974. PubMed PMID: 36656086
Published date: 2023 Jan 19
DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain specific PKM.
Pramio DT, Vieceli FM, Varella-Branco E, Goes CP, Kobayashi GS, da Silva Pelegrina DV, de Moraes BC, El Allam A, De Kumar B, Jara G, Farfel JM, Bennett DA, Kundu S, Viapiano MS, Reis EMR, de Oliveira PSL, Dos Santos E Passos-Bueno MR, Rothlin CV, Ghosh S, Schechtman D
Biochimica et biophysica acta. Gene regulatory mechanisms 1866 (1):194909. PubMed PMID: 36682583
Published date: 2023 Jan 19
Higher Angiotensin I Converting Enzyme 2 (ACE2) levels in the brain of individuals with Alzheimer's disease.
Louise R, Manon L, Vincent E, Andr anne L, Philippe B, Cyntia T, Bennett DA, S bastien H, Fr d ric C
bioRxiv : the preprint server for biology. PubMed PMID: 36711734
Published date: 2023 Jan 18
Vesicular Glutamate Transporter Changes in the Cortical Default Mode Network During the Clinical and Pathological Progression of Alzheimer's Disease.
Mi Z, Abrahamson EE, Ryu AY, Malek-A hmadi M, Kofler JK, Fish KN, Sweet RA, Villemagne VL, Schneider JA, Mufson EJ, Ikonomovic MD
Journal of Alzheimer's disease : JAD 94 (1):227-246. PubMed PMID: 37212097
Published date: 2023
Global Odds Model with Proportional Odds and Trend Odds Applied to Gross and Microscopic Brain Infarcts.
Capuano AW, Wilson R, Schneider JA, Leurgans SE, Bennett DA
Biostatistics & epidemiology. PubMed PMID: 37744066
Published date: 2023
The application of cross-sectionally derived dementia algorithms to longitudinal data in risk factor analyses.
Nichols E, Ng DK, James BD, Deal JA, Gross AL
Annals of epidemiology. PubMed PMID: 36470322
Published date: 2023 Jan
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Yousri NA, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Hwu CM, Hung YJ, Warren HR, Ramirez J, Bork-Jensen J, K rhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Sattar N, M llehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Ruotsalainen SE, Daw E, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Vazquez-Moreno M, Feitosa MF, Wojczynski MK, Wang Z, Preuss MH, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Tsao NL, Verma A, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Hu o S, Ikeda DD, Iha H, Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Frank M, Schmidt B, Smyth LJ, Ca adas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-K h nen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Bayyana S, Stringham HM, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Prasad G, Lor s-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Nardone GG, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas MP, Vaccargiu S, van der Most PJ, Pitk nen N, Cade BE, van der Laan SW, Chitrala KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytik inen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Liang J, Tang H, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, J ger S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, K h nen M, P russe L, Bouchard C, T njes A, Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellstr m D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, He id IM, Stark KJ, Zimmermann ME, V lzke H, Homuth G, Evans MK, Zonderman AB, Polase k O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Kardia SLR, Peyser PA, Kato N, Schulze MB, Girotto G, B ger CA, Jung B, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Tusi -Luna T, Aguilar-Salinas CA, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Hunt SC, Walker M, Koistinen HA, Chandak GR, Mercader JM, Costanzo MC, Jang D, Burtt NP, Villalpando CG, Orozco L, Fornage M, Tai E, van Dam RM, Lehtim ki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, J ckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Qu J, Hishigaki H, Lin X, M rz W, Gudnason V, Tardif JC, Lettre G, Hart LM', Elders PJM, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP, Rotimi CN, Christensen K, Ripatti S, Wid n E, Hakonarson H, Grant SFA, Kiemeney LALM, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, M nnikk M, Jarvelin MR, Kutalik Z, Francesco C, Mook-Kanamori DO, van Dijk KW, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Chuang LM, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, Willemsen AHM, Cupples L, van Meurs JBJ, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A, Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, svold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen Y, Ho YL, Lynch JA, Rader DJ, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson PWF, Frayling TM, Hirschhorn JN, Kathiresan S, Mohlke KL, Sun YV, Morris AP, Boehnke M, Brown CD, Natarajan P, Deloukas P, Willer CJ, Assimes TL, Peloso GM
Genome biology 23 (1):268. PubMed PMID: 36575460
Published date: 2022 Dec 27
AD and non-AD mediators of the pathway between the APOE genotype and cognition.
Nichols E, Brickman AM, Casale tto KB, Dams-O'Connor K, George KM, Kumar RG, Palta P, Rabin JS, Satizabal CL, Schneider J, Pa J, La Joie R
Alzheimer's & dementia : the journal of the Alzheimer's Association 19 (6):2508-2519. PubMed PMID: 36516004
Published date: 2022 Dec 14
A Qualitative Examination of Knowledge, Experiences, and Considerations of PET Brain Scan Participation Among Older Black and Latino Adults.
Glover CM, Arfanakis K, Aggarwal NT, Bennett DA, Marquez DX, Barnes LL
Journal of Alzheimer's disease : JAD 91 (3):961-976. PubMed PMID: 36530086
Published date: 2022 Dec 14
Racial/ethnic disparities in initiation and persistent use of anti-dementia medications.
Zhu CW, Neugroschl J, Barnes LL, Sano M
Alzheimer's & dementia : the journal of the Alzheimer's Association 18 (12):2582-2592. PubMed PMID: 35218291
Published date: 2022 Dec
The Caribbean-Hispanic Alzheimer's disease brain transcriptome reveals ancestry-specific disease mechanisms.
Felsky D, Santa-Maria I, Cosacak MI, French L, Schneider JA, Bennett DA, De Jager PL, Kizil C, Tosto G
Neurobiology of disease. PubMed PMID: 36462719
Published date: 2022 Nov 30
Unified epigenomic, transcriptomic, proteomic, and metabolomic taxonomy of Alzheimer's disease progression and heterogeneity.
Iturria-Medina Y, Adewale Q, Khan AF, Ducharme S, Rosa-Neto P, O'Donnell K, Petyuk VA, Gauthier S, De Jager PL, Breitner J, Bennett DA
Science advances 8 (46):eabo6764. PubMed PMID: 36399579
Published date: 2022 Nov 16
Measurement of Prevalent Versus Incident Dementia Cases in Epidemiologic Studies.
Nichols E, Ng DK, James BD, Deal JA, Gross AL
American journal of epidemiology 192 (4):520-534. PubMed PMID: 36372974
Published date: 2022 Nov 11
Fragmentation of rest periods, astrocyte activation, and cognitive decline in older adults with and without Alzheimer's disease.
Wu R, Tripathy S, Menon V, Yu L, Buchman AS, Bennett DA, De Jager PL, Lim ASP
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 19 (5):1888-1900. PubMed PMID: 36335579
Published date: 2022 Nov 06
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
Blanchard JW, Akay LA, Da vila-Velderrain J, von Maydell D, Mathys H, Davidson SM, Effenberger A, Chen CY, Maner-Smith K, Hajjar I, Ortlund EA, Bula M, Agbas E, Ng A, Jiang X, Kahn M, Blanco-Duque C, Lavoie N, Liu L, Reyes R, Lin YT, Ko T, R'Bibo L, Ralvenius WT, Bennett DA, Cam HP, Kellis M, Tsai LH
Nature 611 (7937):769-779. PubMed PMID: 36385529
Published date: 2022 Nov
Glycoproteomics Landscape of Asymptomatic and Symptomatic Human Alzheimer's Disease Brain.
Suttapitugsakul S, Stavenhagen K, Donskaya S, Bennett DA, Mealer RG, Seyfried NT, Cummings RD
Molecular & cellular proteomics : MCP 21 (12):100433. PubMed PMID: 36309312
Published date: 2022 Oct 26
Cerebrovascular insulin receptors are defective in Alzheimer's disease.
Leclerc M, Bourassa P, Tremblay C, Caron V, Sugre C, Emond V, Bennett DA, Calon F
Brain : a journal of neurology 146 (1):75-90. PubMed PMID: 36280236
Published date: 2022 Oct 25
Frequency and Underlying Pathology of Pure Vascular Cognitive Impairment.
Oveisgharan S, Dawe RJ, Yu L, Kapasi A, Arfanakis K, Hachinski V, Schneider JA, Bennett DA
JAMA neurology 79 (12):1277-1286. PubMed PMID: 36279115
Published date: 2022 Oct 24
A scalable Bayesian functional GWAS method accounting for multivariate quantitative functional annotations with applications for studying Alzheimer disease.
Chen J, Wang L, De Jager PL, Bennett DA, Buchman AS, Yang J
HGG advances 3 (4):100143. PubMed PMID: 36204489
Published date: 2022 Oct 13
A saturated map of common genetic variants associated with human height.
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen SH, Ferreira T, Highland HH, Ji Y, Karaderi T, Lin K, Lll K, Malden DE, Medina-Gomez C, Machado M, Moore A, Reger S, Sim X, Vrieze S, Ahluwalia TS, Akiyama M, Allison MA, Alvarez M, Andersen MK, Ani A, Appadurai V, Arbeeva L, Bhaskar S, Bielak LF, Bollepalli S, Bonnycastle LL, Bork-Jensen J, Bradfield JP, Bradford Y, Braund PS, Brody JA, Burgdorf KS, Cade BE, Cai H, Cai Q, Campbell A, Caadas-Garre M, Catamo E, Chai JF, Chai X, Chang LC, Chang YC, Chen CH, Chesi A, Cho i SH, Chung RH, Cocca M, Concas MP, Couture C, Cuellar-Partida G, Danning R, Daw EW, Degenhard F, Delgado GE, Delitala A, Demirkan A, Deng X, Devineni P, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Ekici AB, Engmann JE, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer L, Francescatto M, Freitag-Wolf S, Fuchsberger C, Galesloot TE, Gao Y, Gao Z, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, He J, Heard-Costa N, Hebbar P, Hindy G, Ho YA, Hofer E, Holliday E, Horn K, Hornsby WE, Hottenga JJ, Huang H, Huang J, Huerta-Chagoya A, Huffman JE, Hung YJ, Huo S, Hwang MY, Iha H, Ikeda DD, Isono M, Jackson AU, Jger S, Jansen IE, Johansson I, Jonas JB, Jonsson A, Jrgensen T, Kalafati IP, Kanai M, Kanoni S, Krhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim HN, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee JY, Leonard HL, Li SA, Li X, Li X, Liang J, Lin H, Lin SY, Liu J, Liu X, Lo KS, Long J, Lores-Motta L, Luan J, Lyssenko V, Lyytikinen LP, Mahajan A, Mamakou V, Mangino M, Manichaikul A, Marten J, Mattheisen M, Mavarani L, McDaid AF, Meidtner K, Melendez TL, Mercader JM, Milaneschi Y, Miller JE, Millwood IY, Mishra PP, Mitchell RE, Mllehave LT, Morgan A, Mucha S, Munz M, Nakatochi M, Nelson CP, Nethander M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R, Ntalla I, Nutile T, Pandit A, Christofidou P, Prna K, Pauper M, Petersen ERB, Petersen LV, Pitknen N, Polaek O, Poveda A, Preuss MH, Pyarajan S, Raffield LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R, Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Saxena R, Scholz M, Sendamarai A, Shen B, Shi J, Shin JH, Sidore C, Sitlani CM, Slieker RC, Smit RAJ, Smith AV, Smith JA, Smy th LJ, Southam L, Steinthorsdottir V, Sun L, Takeuchi F, Tallapragada DSP, Taylor KD, Tayo BO, Tcheandjieu C, Terzikhan N, Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers PRHJ, Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wa ng CA, Wang C, Wang L, Wang Z, Warren HR, Bin Wei W, Wickremasinghe AR, Wielscher M, Wiggins KL, Winsvold BS, Wong A, Wu Y, Wuttke M, Xia R, Xie T, Yamamoto K, Yang J, Yao J, Young H, Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao JH, Zhao W, Zhou W, Zimmermann ME, Zoledziewska M, Adair LS, Adams HHH, Aguilar-Salinas CA, Al-Mulla F, Arnett DK, Asselbergs FW, svold BO, Attia J, Banas B, Bandinelli S, Bennett DA, Bergler T, Bharadwaj D, Biino G, Bisgaard H, Boerwinkle E, Bger CA, Bnnelykke K, Boomsma DI, Brglum AD, Borja JB, Bouchard C, Bowden DW, Brandslund I, Brumpton B, Buring JE, Caulfield MJ, Chambers JC, Chandak GR, Chanock SJ, Chaturvedi N, Chen YI, Chen Z, Cheng CY, Christophersen IE, Ciullo M, Cole JW, Collins FS, Cooper RS, Cruz M, Cucca F, Cupples LA, Cutler MJ, Damrauer SM, Dantoft TM, de Borst GJ, de Groot LCPGM, De Jager PL, de Kleijn DPV, Janaka de Silva H, Dedoussis GV, den Hollander AI, Du S, Easton DF, Elders PJM, Eliassen AH, Ellinor PT, Elmsthl S, Erdmann J, Evans MK, Fatkin D, Feenstra B, Feitosa MF, Ferrucci L, Ford I, Fornage M, Franke A, Franks PW, Freedman BI, Gasparini P, Gieger C, Girotto G, Goddard ME, Golightly 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McGarrah RW, McGue M, McKnight AJ, Medland SE, Mellstrm D, Metspalu A, Mitchell BD, Mitchell P, Mook-Kanamori DO, Morris AD, Mucci LA, Munroe PB, Nalls MA, Nazarian S, Nelson AE, Neville MJ, Newton-Cheh C, Nielsen CS, Nthen MM, Ohlsson C, Oldehinkel AJ, Orozco L, Pahkala K, Pajukanta P, Palmer CNA, Parra EJ, Pattaro C, Pedersen O, Pennell CE, Penninx BWJH, Perusse L, Peters A, Peyser PA, Porteous DJ, Posthuma D, Power C, Pramstaller PP, Province MA, Qi Q, Qu J, Rader DJ, Raitakari OT, Ralhan S, Rallidis LS, Rao DC, Redline S, Reilly DF, Reiner AP, Rhee SY, Ridker PM, Rienstra M, Ripatti S, Ritchie MD, Roden DM, Rosendaal FR, Rotter JI, Rudan I, Rutters F, Sabanayagam C, Saleheen D, Salomaa V, Samani NJ, Sanghera DK, Sattar N, Schmidt B, Schmidt H, Schmidt R, Schulze MB, Schunkert H, Scott LJ, Scott RJ, Sever P, Shiroma EJ, Shoemaker MB, Shu XO, Simonsick EM, Sims M, Singh JR, Singleton AB, Sinner MF, Smith JG, Snieder H, Spector TD, Stampfer MJ, Stark KJ, Strachan DP, 't Hart LM, Tabara Y, Tang H, Tardif JC, Thanaraj TA, Timpson NJ, Tnjes A, Tremblay A, Tuomi T, Tuomilehto J, Tusi-Luna MT, Uitterlinden AG, van Dam RM, van der Harst P, Van der Velde N, van Duijn CM, van Schoor NM, Vitart V, Vlker U, Vollenweider P, Vlzke H, Wacher-Rodarte NH, Walker M, Wang YX, Wareham NJ, Watanabe RM, Watkins H, Weir DR, Werge TM, Widen E, Wilkens LR, Willemsen G, Willett WC, Wilson JF, Wong TY, Woo JT, Wright AF, Wu JY, Xu H, Yajnik CS, Yokota M, Yuan JM, Zeggini E, Zemel BS, Zheng W, Zhu X, Zmuda JM, Zonderman AB, Zwart JA, Chasman DI, Cho YS, Heid IM, McCarthy MI, Ng MCY, O'Donnell CJ, Rivadeneira F, Thorsteinsdottir U, Sun YV, Tai ES, Boehnke M, Deloukas P, Justice AE, Lindgren CM, Loos RJF, Mohlke KL, North KE, Stefansson K, Walters RG, Winkler TW, Young KL, Loh PR, Yang J, Esko T, Assimes TL, Auton A, Abecasis GR, Willer CJ, Locke AE, Berndt SI, Lettre G, Frayling TM, Okada Y, Wood AR, Visscher PM, Hirschhorn JN
Nature 610 (7933):704-712. PubMed PMID: 36224396
Published date: 2022 Oct 12
Alzheimer's disease-associated U1 snRNP splicing dysfunction causes neuronal hyperexcitability and cognitive impairment.
Chen PC, Han X, Shaw TI, Fu Y, Sun H, Niu M, Wang Z, Jiao Y, Teubner BJW, Eddins D, Beloate LN, Bai B, Mertz J, Li Y, Cho JH, Wang X, Wu Z, Liu D, Poudel S, Yuan ZF, Mancieri A, Low J, Lee HM, Patton MH, Earls LR, Stewart E, Vogel P, Hui Y, Wan S, Bennett DA, Serrano GE, Beach TG, Dyer MA, Smeyne RJ, Moldoveanu T, Chen T, Wu G, Zakharenko SS, Yu G, Peng J
Nature aging 2 (10):923-940. PubMed PMID: 36636325
Published date: 2022 Oct
Stroke genetics informs drug discovery and risk prediction across ancestries.
Mishra A, Malik R, Hachiya T, Jrgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi M, He Y, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Crcel-Mrquez J, Nygaard M, Leonard HL, Yang C, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Brte S, Cain A, Ridker PM, Cho K, Chen Z, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li L, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-Moret NC, Ovbiagele B, Peters A, Psaty BM, Rich SS, Rosand J, Sabatine MS, Sacco RL, Saleheen D, Sandset EC, Salomaa V, Sargurupremraj M, Sasaki M, Satizabal CL, Schmidt CO, Shimizu A, Smith NL, Sloane KL, Sutoh Y, Sun YV, Tanno K, Tiedt S, Tatlisumak T, Torres-Aguila NP, Tiwari HK, Trgout DA, Trompet S, Tuladhar AM, Tybjrg-Hansen A, van Vugt M, Vibo R, Verma SS, Wiggins KL, Wennberg P, Woo D, Wilson PWF, Xu H, Yang Q, Yoon K, Millwood IY, Gieger C, Ninomiya T, Grabe HJ, Jukema JW, Rissanen IL, Strbian D, Kim YJ, Chen PH, Mayerhofer E, Howson JMM, Irvin MR, Adams H, Wassertheil-Smoller S, Christensen K, Ikram MA, Rundek T, Worrall BB, Lathrop GM, Riaz M, Simonsick EM, Krv J, Frana PHC, Zand R, Prasad K, Frikke-Schmidt R, de Leeuw FE, Liman T, Haeusler KG, Ruigrok YM, Heuschmann PU, Longstreth WT, Jung KJ, Bastarache L, Par G, Damrauer SM, Chasman DI, Rotter JI, Anderson CD, Zwart JA, Niiranen TJ, Fornage M, Liaw YP, Seshadri S, Fernndez-Cadenas I, Walters RG, Ruff CT, Owolabi MO, Huffman JE, Milani L, Kamatani Y, Dichgans M, Debette S
Nature 611 (7934):115-123. PubMed PMID: 36180795
Published date: 2022 Sep 30
Author Response: Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults.
Oveisgharan S, Bennett DA, Buchman AS
Neurology 99 (13):586. PubMed PMID: 36163332
Published date: 2022 Sep 27
Mitochondrial DNA variation in Alzheimer's disease reveals a unique microprotein called SHMOOSE.
Miller B, Kim SJ, Mehta HH, Cao K, Kumagai H, Thumaty N, Leelaprachakul N, Jiao H, Vaughan J, Diedrich J, Saghatelian A, Arpawong TE, Crimmins EM, Ertekin-Taner N, Tubi MA, Hare ET, Braskie MN, Dcarie-Spain L, Kanoski SE, Grodstein F, Bennett DA, Zhao L, Toga AW, Wan J, Yen K, Cohen P
Molecular psychiatry 28 (4):1813-1826. PubMed PMID: 36127429
Published date: 2022 Sep 21
Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.
Hsieh YC, Negri J, He A, Pearse RV, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration 17 (1):61. PubMed PMID: 36131294
Published date: 2022 09 21
Cognitive decline and hippocampal functional connectivity within older Black adults.
Han SD, Fleischman DA, Yu L, Poole V, Lamar M, Kim N, Leurgans SE, Bennett DA, Arfanakis K, Barnes LL
Human brain mappingREFERENCES 43 (16):5044-5052. PubMed PMID: 36066181
Published date: 2022 Sep 06
Longitudinal change in serial position scores in older adults with entorhinal and hippocampal neuropathologies.
Gicas KM, Honer WG, Leurgans SE, Wilson RS, Boyle PA, Schneider JA, Bennett DA
Journal of the International Neuropsychological Society : JINS 29 (6):1-11. PubMed PMID: 36062540
Published date: 2022 Sep 05
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation.
Tazwar M, Evia AM, Tamhane AA, Ridwan AR, Leurgans SE, Bennett DA, Schneider JA, Arfanakis K
Neurobiology of aging. PubMed PMID: 35728463
Published date: 2022 09
Circulating Cell-Free Genomic DNA Is Associated with an Increased Risk of Dementia and with Change in Cognitive and Physical Function.
Nidadavolu LS, Feger D, Wu Y, Grodstein F, Gross AL, Bennett DA, Walston JD, Oh ES, Abadir PM
Journal of Alzheimer's disease : JAD 89 (4):1233-1240. PubMed PMID: 36031893
Published date: 2022 Aug 20
Risk Models Based on Non-Cognitive Measures May Identify Presymptomatic Alzheimer's Disease.
Yang J, Oveisgharan S, Liu X, Wilson RS, Bennett DA, Buchman AS
Journal of Alzheimer's disease : JAD 89 (4):1249-1262. PubMed PMID: 35988224
Published date: 2022 Aug 17
Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning.
Lahti J, Tuominen S, Yang Q, Pergola G, Ahmad S, Amin N, Armstrong NJ, Beiser A, Bey K, Bis JC, Boerwinkle E, Bressler J, Campbell A, Campbell H, Chen Q, Corley J, Cox SR, Davies G, De Jager PL, Derks EM, Faul JD, Fitzpatrick AL, Fohner AE, Ford I, Fornage M, Gerring Z, Grabe HJ, Grodstein F, Gudnason V, Simonsick E, Holliday EG, Joshi PK, Kajantie E, Kaprio J, Karell P, Kleineidam L, Knol MJ, Kochan NA, Kwok JB, Leber M, Lam M, Lee T, Li S, Loukola A, Luck T, Marioni RE, Mather KA, Medland S, Mirza SS, Nalls MA, Nho K, O'Donnell A, Oldmeadow C, Painter J, Pattie A, Reppermund S, Risacher SL, Rose RJ, Sadashivaiah V, Scholz M, Satizabal CL, Schofield PW, Schraut KE, Scott RJ, Simino J, Smith AV, Smith JA, Stott DJ, Surakka I, Teumer A, Thalamuthu A, Trompet S, Turner ST, van der Lee SJ, Villringer A, Vlker U, Wilson RS, Wittfeld K, Vuoksimaa E, Xia R, Yaffe K, Yu L, Zare H, Zhao W, Ames D, Attia J, Bennett DA, Brodaty H, Chasman DI, Goldman AL, Hayward C, Ikram MA, Jukema JW, Kardia SLR, Lencz T, Loeffler M, Mattay VS, Palotie A, Psaty BM, Ramirez A, Ridker PM, Riedel-Heller SG, Sachdev PS, Saykin AJ, Scherer M, Schofield PR, Sidney S, Starr JM, Trollor J, Ulrich W, Wagner M, Weir DR, Wilson JF, Wrigh t MJ, Weinberger DR, Debette S, Eriksson JG, Mosley TH, Launer LJ, van Duijn CM, Deary IJ, Seshadri S, Rikknen K
Molecular psychiatry 27 (11):4419-4431. PubMed PMID: 35974141
Published date: 2022 Aug 16
Fine-mapping and replication of EWAS loci harboring putative epigenetic alterations associated with AD neuropathology in a large collection of human brain tissue samples.
Palma-Gudiel H, Yu L, Huo Z, Yang J, Wang Y, Gu T, Gao C, De Jager PL, Jin P, Bennett DA, Zhao J
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 19 (4):1216-1226. PubMed PMID: 35959851
Published date: 2022 Aug 12
APOE 4 and Alzheimer's disease diagnosis associated differences in L-carnitine, GBB, TMAO, and acylcarnitines in blood and brain.
Huguenard CJC, Cseresznye A, Evans JE, Darcey T, Nkiliza A, Keegan AP, Luis C, Bennett DA, Arvanitakis Z, Yassine HN, Mullan M, Crawford F, Abdullah L
Current research in translational medicine 71 (1):103362. PubMed PMID: 36436355
Published date: 2022 Aug 11
Association of AK4 Protein From Stem Cell-Derived Neurons With Cognitive Reserve: An Autopsy Study.
Yu L, Hsieh YC, Pearse RV, Wang Y, Petyuk V, Schneider JA, Buchman AS, Seyfried NT, De Jager PL, Young-Pearse TL, Bennett DA
Neurology 99 (20):e2264-e2274. PubMed PMID: 35948448
Published date: 2022 Aug 10
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, Winkler TW, Locke AE, Marouli E, Zajac GJM, Wu KH, Ntalla I, Hui Q, Klarin D, Hilliard AT, Wang Z, Xue C, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Hwang MY, Han S, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Havulinna AS, Veturi Y, Pacheco JA, Rosenthal EA, Lingren T, Feng Q, Kullo IJ, Narita A, Takayama J, Martin HC, Hunt KA, Trivedi B, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Rasheed A, Hindy G, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Choudhury A, Sengupta D, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Bjerregaard AA, Yao J, Manichaikul A, Lee WJ, Hsiung CA, Warren HR, Ramirez J, Bork-Jensen J, Krhus LL, Goel A, Sabater-Lleal M, Noordam R, Mauro P, Matteo F, McDaid AF, Marques-Vidal P, Wielscher M, Trompet S, Satt ar N, Mllehave LT, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Schnherr S, Forer L, Scholz M, Galesloot TE, Bradfield JP, Ruotsalainen SE, Daw EW, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Le P, Feitosa MF, Wojczynski MK, Hemerich D, Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Noah TL, Verma A, Slieker RC, Lo KS, Zilhao NR, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Demirkan A, Leonard HL, Marten J, Emmel C, Schmidt B, Smyth LJ, Caadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Khnen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Nongmaithem SS, Sankareswaran A, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Prasad G, Lors-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Chen S, Liu F, Yang J, Kentistou KA, Banas B, Morgan A, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Concas MP, Vaccargiu S, van der Most PJ, Pitknen N, Cade BE, van der Laan SW, Chitrala KN, Weiss S, Bentley AR, Doumatey AP, Adeyemo AA, Lee JY, Petersen ERB, Nielsen AA, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hidalgo B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, He KY, Tang H, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Kawaguchi T, Thiery J, Bis JC, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jger S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Khnen M, Prusse L, Bouchard C, Tnjes A, Ida Chen YD, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellstrm D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Zimmermann ME, Vlzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Bandinelli S, Dedoussis G, Thanaraj TA, Peyser PA, Kato N, Schulze MB, Girotto G, Bger CA, Jung B, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kapr io J, Pajukanta P, Tusi-Luna T, Aguilar-Salinas CA, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Walker M, Scott LJ, Koistinen HA, Chandak GR, Mercader JM, Villalpando CG, Orozco L, Fornage M, Ta i ES, van Dam RM, Lehtimki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Jin ZB, Lu F, Hishigaki H, Lin X, Mrz W, Gudnason V, Tardif JC, Lettre G, T Hart LM, Elders PJM, Rader DJ, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Parra EJ, Cruz M, Psaty BM, Brandslund I, Pramstaller PP, Rotimi CN, Christensen K, Ripatti S, Widn E, Hakonarson H, Grant SFA, Kiemeney L, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, Mnnikk M, Jarvelin MR, Kutalik Z, Francesco C, Mook-Kanamori DO, Willems van Dijk K, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Huey-Herng Sheu W, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Li H, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, de Geus EJC, Cupples LA, van Meurs JBJ, Ikram A, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Tuomilehto J, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, Hazelhurst S, Ramsay M, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Baras A, Justice AE, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Tamiya G, Yamamoto M, van Heel DA, Trembath RC, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, svold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Kim BJ, Thorsteinsdottir U, Stefansson K, Zhang J, Chen YE, Ho YL, Lynch JA, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson P, Mohlke KL, Frayling TM, Hirschhorn JN, Kathiresan S, Boehnke M, Struan Grant, Natarajan P, Sun YV, Morris AP, Deloukas P, Peloso G, Assimes TL, Willer CJ, Zhu X, Brown CD
American journal of human genetics 109 (8):1366-1387. PubMed PMID: 35931049
Published date: 202 2 08 04
Genetics of the human microglia regulome refines Alzheimer's disease risk loci.
Kosoy R, Fullard JF, Zeng B, Bendl J, Dong P, Rahman S, Kleopoulos SP, Shao Z, Girdhar K, Humphrey J, de Paiva Lopes K, Charney AW, Kopell BH, Raj T, Bennett D, Kellner CP, Haroutunian V, Hoffman GE, Roussos P
Nature genetics 54 (8):1145-1154. PubMed PMID: 35931864
Published date: 2022 Aug
Black and White individuals differ in dementia prevalence, risk factors, and symptomatic presentation.
Lennon JC, Aita SL, Bene VAD, Rhoads T, Resch ZJ, Eloi JM, Walker KA
Alzheimer's & dementia : the journal of the Alzheimer's Association 18 (8):1461-1471. PubMed PMID: 34854531
Published date: 2022 Aug
Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease.
Thrush KL, Bennett DA, Gaiteri C, Horvath S, Dyck CHV, Higgins-Chen AT, Levine ME
Aging 14 (14):5641-5668. PubMed PMID: 35907208
Published date: 2022 Jul 30
The landscape of metabolic brain alterations in Alzheimer's disease.
Batra R, Arnold M, Wrheide MA, Allen M, Wang X, Blach C, Levey AI, Seyfried NT, Ertekin-Taner N, Bennett DA, Kastenmller G, Kaddurah-Daouk RF, Krumsiek J
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES. PubMed PMID: 35829654
Published date: 2022 Jul 13
Development of High Quality T1-weighted and Diffusion Tensor Templates of the Older Adult Brain in a Common Space.
Wu Y, Ridwan AR, Niaz MR, Qi X, Zhang S, Alzheimer's Disease Neuroimaging Initiative, Bennett DA, Arfanakis K
NeuroImage. PubMed PMID: 35793748
Published date: 2022 Jul 03
FMNL2 regulates gliovascular interactions and is associated with vascular risk factors and cerebrovascular pathology in Alzheimer's disease.
Lee AJ, Raghavan NS, Bhattarai P, Siddiqui T, Sariya S, Reyes-Dumeyer D, Flowers XE, Cardoso SAL, De Jager PL, Bennett DA, Schneider JA, Menon V, Wang Y, Lantigua RA, Medrano M, Rivera D, Jimnez -Velzquez IZ, Kukull WA, Brickman AM, Manly JJ, Tosto G, Kizil C, Vardarajan BN, Mayeux R
Acta neuropathologica 144 (1):59-79. PubMed PMID: 35608697
Published date: 2022 Jul
Acute versus chronic inflammatory markers and cognition in older black adults: Results from the Minority Aging Research Study.
Boots EA, Feinstein DL, Leurgans S, Aiken-Morgan AT, Fleischman DA, Lamar M, Barnes LL
Brain, behavior, and immunity. PubMed PMID: 35439553
Published date: 2022 07
LDL cholesterol is associated with higher AD neuropathology burden independent of APOE.
Wingo AP, Vattathil SM, Liu J, Fan W, Cutler DJ, Levey AI, Schneider JA, Bennett DA, Wingo TS
Journal of neurology, neurosurgery, and psychiatry 93 (9):930-8. PubMed PMID: 35772923
Published date: 2022 Jun 30
Integrative Co-methylation Network Analysis Identifies Novel DNA Methylation Signatures and Their Target Genes in Alzheimer's Disease.
Kim JP, Kim BH, Bice PJ, Seo SW, Bennett DA, Saykin AJ, Nho K
Biological psychiatry 93 (9):842-851. PubMed PMID: 36150909
Published date: 2022 Jun 24
Neurodegenerative and cerebrovascular brain pathologies are differentially associated with declining grip strength and gait in older adults.
Oveisgharan S, Yu L, Wang T, Schneider JA, Bennett DA, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 78 (3):504-513. PubMed PMID: 35675284
Published date: 2022 Jun 08
Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, Hernandez Saucedo H, Widaman KF, Buckley RF, Properzi MJ, Mormino EC, Yang HS, Harrison TM, Hedden T, Nho K, Andrews SJ, Tommet D, Hadad N, Sanders RE, Ruderfer DM, Gifford KA, Zhong X, Raghavan NS, Vardarajan BN, Pericak-Vance MA, Farrer LA, Wang LS, Cruchaga C, Schellenberg GD, Cox NJ, Haines JL, Keene CD, Saykin AJ, Larson EB, Sperling RA, Mayeux R, Cuccaro ML, Bennett DA, Schneider JA, Crane PK, Jefferson AL, Hohman TJ
Brain : a journal of neurology 145 (7):2541-2554. PubMed PMID: 35552371
Published date: 2022 May 13
Association of Statins With Cerebral Atherosclerosis and Incident Parkinsonism in Older Adults.
Oveisgharan S, Yu L, Barnes LL, Agrawal S, Schneider JA, Bennett DA, Buchman AS
Neurology 98 (19):e1976-e1984. PubMed PMID: 35321928
Published date: 2022 05 10
Proteome-wide discovery of cortical proteins that may provide motor resilience to offset the negative effects of pathologies in older adults.
Buchman AS, Yu L, Klein HU, Zammit AR, Oveisgharan S, Grodstein F, Tasaki S, Levey AI, Seyfried NT, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 78 (3):494-503. PubMed PMID: 35512265
Published date: 2022 May 04
Relationship of Blood Pressure and White Matter Hyperintensity Burden With Level of and Change in Cognition in Older Black Adults.
Lamar M, Fleischman DA, Leurgans SE, Aggarwal N, Yu L, Kim N, Poole V, Han SD, Arfanakis K, Barnes LL
Psychosomatic medicine 84 (4):437-445. PubMed PMID: 35100182
Published date: 2022 05 01
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder.
Wingo TS, Gerasimov ES, Liu Y, Duong DM, Vattathil SM, Lori A, Gockley J, Breen MS, Maihofer AX, Nievergelt CM, Koenen KC, Levey DF, Gelernter J, Stein MB, Ressler KJ, Bennett DA, Levey AI, Seyfried NT, Wingo AP
Molecular psychiatry 27 (7):3075-3084. PubMed PMID: 35449297
Published date: 2022 Apr 21
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
Heath L, Earls JC, Magis AT, Kornilov SA, Lovejoy JC, Funk CC, Rappaport N, Logsdon BA, Mangravite LM, Kunkle BW, Martin ER, Naj AC, Ertekin-Taner N, Golde TE, Hood L, Price ND
Scientific reports 12 (1):6117. PubMed PMID: 35413975
Published date: 2022 Apr 12
Limbic-Predominant Age-Related TDP-43 Encephalopathy: Medical and Pathologic Factors Associated With Comorbid Hippocampal Sclerosis.
Gauthreaux KM, Teylan MA, Katsumata Y, Mo ck C, Culhane JE, Chen YC, Chan KCG, Fardo DW, Dugan AJ, Cykowski MD, Jicha GA, Kukull WA, Nelson PT
Neurology 98 (14):e1422-e1433. PubMed PMID: 35121671
Published date: 2022 Apr 05
Modifiable psychosocial risk factors and delayed onset of dementia in older populations: analysis of two prospective US cohorts.
Grodstein F, Wang T, Leurgans SE, Wilson RS, Bennett DA
BMJ open 12 (4):e059317. PubMed PMID: 35379643
Published date: 2022 Apr 04
Neuronal C/EBP/AEP pathway shortens life span via selective GABAnergic neuronal degeneration by FOXO repression.
Xia Y, Qadota H, Wang ZH, Liu P, Liu X, Ye KX, Matheny CJ, Berglund K, Yu SP, Drake D, Bennett DA, Wang XC, Yankner BA, Benian GM, Ye K
Science advances 8 (13):eabj8658. PubMed PMID: 35353567
Published date: 2022 Apr
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.
Okbay A, Wu Y, Wang N, Jayashankar H, Bennett M, Nehzati SM, Sidorenko J, Kweon H, Goldman G, Gjorgjieva T, Jiang Y, Hicks B, Tian C, Hinds DA, Ahlskog R, Magnusson PKE, Oskarsson S, Hayward C, Campbell A, Porteous DJ, Freese J, Herd P, Watson C, Jala J, Conley D, Koellinger PD, Johannesson M, Laibson D, Meyer MN, Lee JJ, Kong A, Yengo L, Cesarini D, Turley P, Visscher PM, Beauchamp JP, Benjamin DJ, Young AI
Nature genetics 54 (4):437-449. PubMed PMID: 35361970
Published date: 2022 Apr
Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons.
Agrawal S, Leurgans SE, James BD, Barnes LL, Mehta RI, Dams-O'Connor K, Mez J, Bennett DA, Schneider JA
JAMA network open 5 (4):e229311. PubMed PMID: 35476062
Published date: 2022 Apr 01
Associations Between Neuropsychiatric Symptoms and Neuropathological Diagnoses of Alzheimer Disease and Related Dementias.
Devanand DP, Lee S, Huey ED, Goldberg TE
JAMA psychiatry 79 (4):359-367. PubMed PMID: 35171235
Published date: 2022 Apr 01
A Novel Method for Establishing Functional Change in Older Adults With Cognitive Impairment.
Gonzlez DA, Resch ZJ, Gonzales MM, Soble JR
Alzheimer disease and associated disorders 36 (3):238-243. PubMed PMID: 35380552
Published date: 2022 Mar 31
Progression to Dementia or Reversion to Normal Cognition in Mild Cognitive Impairment as a Function of Late Onset Neuropsychiatric Symptoms.
McGirr A, Nathan S, Ghahremani M, Gill S, Smith E, Ismail Z
Neurology 98 (21):e2132-e2139. PubMed PMID: 35351783
Published date: 2022 Mar 29
Cortical Proteins and Individual Differences in Cognitive Resilience in Older Adults.
Zammit AR, Yu L, Petyuk V, Schneider JA, De Jager PL, Klein HU, Bennett DA, Buchman AS
Neurology 98 (13):e1304-e1314. PubMed PMID: 35241503
Published date: 2022 Mar 29
Global cognitive trajectory patterns in Alzheimer's disease.
Cohen CI, Reisberg B, Yaffee R
International psychogeriatrics 36 (3):1-10. PubMed PMID: 35331359
Published date: 2022 Mar 25
Clinicopathologic Factors Associated With Reversion to Normal Cognition in Patients With Mild Cognitive Impairment.
Li Z, Heckman MG, Kanekiyo T, Martens YA, Day GS, Vassilaki M, Liu CC, Bennett DA, Petersen RC, Zhao N, Bu G
Neurology 98 (20):e2036-e2045. PubMed PMID: 35314499
Published date: 2022 Mar 21
Integrating whole-genome sequencing with multi-omic data reveals the impact of structural variants on gene regulation in the human brain.
Vialle RA, de Paiva Lopes K, Bennett DA, Crary JF, Raj T
Nature neuroscience 25 (4):504-514. PubMed PMID: 35288716
Published date: 2022 Mar 14
Identification of the A37/42 peptide ratio in CSF as an improved A biomarker for Alzheimer's disease.
Liu L, Lauro BM, He A, Lee H, Bhattarai S, Wolfe MS, Bennett DA, Karch CM, Young-Pearse T, Selkoe DJ
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 19 (1):79-96. PubMed PMID: 35278341
Published date: 2022 Mar 12
Predictors of Mortality in Individuals with Dementia in the National Alzheimer's Coordinating Center.
Armstrong MJ, Song S, Kurasz AM, Li Z
Journal of Alzheimer's disease : JAD 86 (4):1935-1946. PubMed PMID: 35253760
Published date: 2022 Mar 03
Association of Variation in Behavioral Symptoms With Initial Cognitive Phenotype in Adults With Dementia Confirmed by Neuropathology.
Pillai JA, Bena J, Rothenberg K, Boron B, Leverenz JB
JAMA network open 5 (3):e220729. PubMed PMID: 35238936
Published date: 2022 Mar 01
The vascular risk factors and vascular neuropathology in subjects with autopsy-confirmed dementia with Lewy bodies.
Chen ZC, Gan J, Yang Y, Meng Q, Han J, Ji Y
International journal of geriatric psychiatryREFERENCES 37 (3):15333175211070912. PubMed PMID: 35128731
Published date: 2022 Mar
Association of small vessel disease with tau pathology.
Kapasi A, Yu L, Petyuk V, Arfanakis K, Bennett DA, Schneider JA
Acta neuropathologica 143 (3):349-362. PubMed PMID: 35044500
Published date: 2022 03
Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia.
Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL
Neurobiology of aging 111 (6):35-43. PubMed PMID: 34963062
Published date: 2022 03
Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes.
Dugan AJ, Nelson PT, Katsumata Y, Shade LMP, Teylan MA, Boehme KL, Mukherjee S, Kauwe JSK, Hohman TJ, Schneider JA, Fardo DW
Neurobiology of aging. PubMed PMID: 34852950
Published date: 2022 03
The complex relationship between depression and progression to incident cognitive impairment across race and ethnicity.
Babulal GM, Zhu Y, Roe CM, Hudson DL, Williams MM, Murphy SA, Doherty J, Johnson AM, Trani JF
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (12):2593-2602. PubMed PMID: 35213795
Published date: 2022 Feb 25
Correlates of Conversion from Mild Cognitive Impairment to Dementia with Lewy Bodies: Data from the National Alzheimer Coordinating Center.
Payne S, Shofer JB, Shutes-David A, Li G, Jankowski A, Dean P, Tsuang D
Journal of Alzheimer's disease : JAD 86 (4):1643-1654. PubMed PMID: 35213374
Published date: 2022 Feb 23
Brain DNA Methylation Patterns in CLDN5 Associated With Cognitive Decline.
H ls A, Robins C, Conneely KN, Edg ar R, De Jager PL, Bennett DA, Wingo AP, Epstein MP, Wingo TS
Biological psychiatry 91 (4):389-398. PubMed PMID: 33838873
Published date: 2022 Feb 15
Single-cell dissection of the human brain vasculature.
Garcia FJ, Sun N, Lee H, Godlewski B, Galani K, Zhou B, Mantero J, Bennett DA, Sahin M, Kellis M, Heiman M
Nature 603 (7903):893-899. PubMed PMID: 35158371
Published date: 2022 Feb 14
Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE 2 for Alzheimer's disease.
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W, Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (11):2042-2054. PubMed PMID: 35142023
Published date: 2022 Feb 09
Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population.
Godrich D, Martin ER, Schellenberg G, Pericak-Vance MA, Cuccaro M, Scott WK, Kukull W, Montine T, Beecham GW
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (12):2403-2412. PubMed PMID: 35142102
Published date: 2022 Feb 09
Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease.
Panitch R, Hu J, Xia W, Bennett DA, Stein TD, Farrer LA, Jun GR
Alzheimer's research & therapy 14 (1):30. PubMed PMID: 35139885
Published date: 2022 02 09
Progranulin mutations in clinical and neuropathological Alzheimer's disease.
Vardarajan BN, Reyes-Dumeyer D, Piriz AL, Lantigua RA, Medrano M, Rivera D, Jimnez-Velzquez IZ, Martin E, Pericak-Vance MA, Bush W, Farrer L, Haines JL, Wang LS, Leung YY, Schellenberg G, Kukull W, De Jager P, Bennett DA, Schneider JA, Mayeux R
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (12):2458-2467. PubMed PMID: 35258170
Published date: 2022 Feb 09
Inferring protein expression changes from mRNA in Alzheimer's dementia using deep neural networks.
Tasaki S, Xu J, Avey DR, Johnson L, Petyuk VA, Dawe RJ, Bennett DA, Wang Y, Gaiteri C
Nature communications 13 (1):655. PubMed PMID: 35115553
Published date: 2022 02 03
Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level.
Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, Zhang B, Gaiteri C, Bennett DA, Gearing M, Wingo TS, Wingo AP, Lah JJ, Levey AI, Seyfried NT
Nature neuroscience 25 (2):213-225. PubMed PMID: 35115731
Published date: 2022 Feb
Quantifying longitudinal cognitive resilience to Alzheimer's disease and other neuropathologies.
Wagner M, Wilson RS, Leurgans SE, Boyle PA, Bennett DA, Grodstein F, Capuano AW
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (11):2252-2261. PubMed PMID: 35102704
Published date: 2022 Feb 01
Mild behavioral impairment is associated with progression to Alzheimer's disease: A clinicopathological study.
Ruthirakuhan M, Ismail Z, Herrmann N, Gallagher D, Lanctt KL
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (11):2199-2208. PubMed PMID: 35103400
Published date: 2022 Feb 01
Brain microRNAs are associated with variation in cognitive trajectory in advanced age.
Wingo AP, Wang M, Liu J, Breen MS, Yang HS, Tang B, Schneider JA, Seyfried NT, Lah JJ, Levey AI, Bennett DA, Jin P, De Jager PL, Wingo TS
Translational psychiatry 12 (1):47. PubMed PMID: 35105862
Published date: 2022 Feb 01
Examination of race and gender differences in predictors of neuropsychological decline and development of Alzheimer's disease.
Johnson EEH, Alexander C, Lee GJ, Angers K, Ndiaye D, Suhr J
The Clinical neuropsychologist 36 (2):327-352. PubMed PMID: 34218735
Published date: 2022 Feb
Diagnostic accuracy and differential associations between ratings of functioning and neuropsychological performance in non-Hispanic Black and White older adults.
Graves LV, Edmonds EC, Thomas KR, Weigand AJ, Cooper S, Stickel AM, Zlatar ZZ, Clark AL, Bondi MW
The Clinical neuropsychologist 36 (2):287-310. PubMed PMID: 34499580
Published date: 2022 Feb
Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study.
Dugan AJ, Nelson PT, Katsumata Y, Shade LMP, Boehme KL, Teylan MA, Cykowski MD, Mukherjee S, Kauwe JSK, Hohman TJ, Schneider JA, Fardo DW
Acta neuropathologica communications 9 (1):152. PubMed PMID: 34526147
Published date: 20 21 09 15
Co-expression Network Analysis of Frontal Cortex during the Progression of Alzheimer's Disease.
Beck JS, Madaj Z, Cheema CT, Kara B, Bennett DA, Schneider JA, Gordon MN, Ginsberg SD, Mufson EJ, Counts SE
Cerebral cortex (New York, N.Y. : 1991) 32 (22):5108-5120. PubMed PMID: 35076713
Published date: 2022 Jan 24
The National Institute on Aging Late-Onset Alzheimer's Disease Family Based Study: A resource for genetic discovery.
Reyes-Dumeyer D, Faber K, Vardarajan B, Goate A, Renton A, Chao M, Boeve B, Cruchaga C, Pericak-Vance M, Haines JL, Rosenberg R, Tsuang D, Sweet RA, Bennett DA, Wilson RS, Foroud T, Mayeux R
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (10):1889-1897. PubMed PMID: 34978149
Published date: 2022 Jan 03
Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain.
Niaz MR, Ridwan AR, Wu Y, Initiative ADN, Bennett DA, Arfanakis K
NeuroImage. PubMed PMID: 34986396
Published date: 2022 Jan 02
Predictors of Life Expectancy in Autopsy-Confirmed Alzheimer's Disease.
Schaffert J, LoBue C, Hynan LS, Hart J, Rossetti H, Carlew AR, Lacritz L, White CL, Cullum CM
Journal of Alzheimer's disease : JAD 86 (1):271-281. PubMed PMID: 35034898
Published date: 2022
Reassessing Diabetes and APOE Genotype as Potential Interacting Risk Factors for Alzheimer's Disease.
Ravipati K, Chen Y, Manns JR
American journal of Alzheimer's disease and other dementias. PubMed PMID: 35041557
Published date: 2022 Jan-Dec
Alzheimer disease in African American individuals: increased incidence or not enough data?
Barnes LL
Nature reviews. Neurology 18 (1):56-62. PubMed PMID: 34873310
Published date: 2022 01
Gastric acid suppressants and cognitive decline in people with or without cognitive impairment.
Wu CY, Xiong LY, Ouk M, Rabin JS, Herrmann N, Lanctt KL, Kapral MK, Law M, Cogo-Moreira H, Edwards JD, Swardfager W
Alzheimer's & dementia (New York, N. Y.) 8 (1):e12243. PubMed PMID: 35169610
Published date: 2022
The impact of hearing impairment and hearing aid use on progression to mild cognitive impairment in cognitively healthy adults: An observational cohort study.
Bucholc M, Bauermeister S, Kaur D, McClean PL, Todd S
Alzheimer's & dementia (New York, N. Y.) 8 (1):e12248. PubMed PMID: 35229022
Published date: 2022
Neuropsychiatric Inventory-Questionnaire Assessed Nighttime Behaviors in Cognitively Asymptomatic Patients with Pathologically Confirmed Alzheimer's Disease Predict More Rapid Cognitive Deterioration.
Atayde AL, Fischer CE, Schweizer TA, Munoz DG
Journal of Alzheimer's disease : JAD 86 (3):1137-1147. PubMed PMID: 35180114
Published date: 2022
Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline.
Lamar M, Leurgans S, Kapasi A, Barnes LL, Boyle PA, Bennett DA, Arfanakis K, Schneider JA
Stroke 53 (1):218-227. PubMed PMID: 34601898
Published date: 2022 01
Derivation and validation of the Rapid Assessment of Dementia Risk (RADaR) for older adults.
Capuano AW, Shah RC, Blanche P, Wilson RS, Barnes LL, Bennett DA, Arvanitakis Z
PloS one 17 (3):e0265379. PubMed PMID: 35299231
Published date: 2022
Specific depression dimensions are associated with a faster rate of cognitive decline in older adults.
Soleimani L, Schnaider Beeri M, Grossman H, Sano M, Zhu CW
Alzheimer's & dementia (Amsterdam, Netherlands) 14 (1):e12268. PubMed PMID: 35317432
Published date: 2022
Polygenic Risk Score Effectively Predicts Depression Onset in Alzheimer's Disease Based on Major Depressive Disorder Risk Variants.
Upadhya S, Liu H, Luo S, Lutz MW, Chiba-Falek O
Frontiers in neuroscience. PubMed PMID: 35350557
Published date: 2022
GW5074 Increases Microglial Phagocytic Activities: Potential Therapeutic Direction for Alzheimer's Disease.
Connor SM, Rashid M, Ryan KJ, Patel K, Boyd JD, Smith J, Elyaman W, Bennett DA, Bradshaw EM
Frontiers in cellular neuroscience. PubMed PMID: 35677758
Published date: 2022
Bulk and Single-Nucleus Transcriptomics Highlight Intra-Telencephalic and Somatostatin Neurons in Alzheimer's Disease.
Consens ME, Chen Y, Menon V, Wang Y, Schneider JA, De Jager PL, Bennett DA, Tripathy SJ, Felsky D
Frontiers in molecular neuroscience. PubMed PMID: 35754708
Published date: 2022
Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders.
Kelley CM, Ginsberg SD, Liang WS, Counts SE, Mufson EJ
Brain communications 4 (4):fcac162. PubMed PMID: 35813880
Published date: 2022
The unique effect of TDP-43 on hippocampal subfield morphometry and cognition.
Heywood A, Stocks J, Schneider JA, Arfanakis K, Bennett DA, Beg MF, Wang L
NeuroImage. Clinical. PubMed PMID: 36002965
Published date: 2022
Neuropathological and Clinical Correlates of Lewy Body Disease Survival by Race and Ethnicity in the National Alzheimer's Coordinating Center.
Kurasz AM, De Wit L, Smith GE, Armstrong MJ
Journal of Alzheimer's disease : JAD 89 (4):1339-1349. PubMed PMID: 36031892
Published date: 2022
Altered levels of variant cholinesterase transcripts contribute to the imbalanced cholinergic signaling in Alzheimer's and Parkinson's disease.
Gok M, Madrer N, Zorbaz T, Bennett ER, Greenberg D, Bennett DA, Soreq H
Frontiers in molecular neuroscience. PubMed PMID: 36117917
Published date: 2022
Vascular pathology and pathogenesis of cognitive impairment and dementia in older adults.
Agrawal S, Schneider JA
Cerebral circulation - cognition and behavior 3 (4):100148. PubMed PMID: 36324408
Published date: 2022
Cell type-specific histone acetylation profiling of Alzheimer's disease subjects and integration with genetics.
Ramamurthy E, Welch G, Cheng J, Yuan Y, Gunsalus L, Bennett DA, Tsai LH, Pfenning AR
Frontiers in molecular neuroscience. PubMed PMID: 36683855
Published date: 2022
Evidence of Filamin A loss of solubility at the prodromal stage of neuropathologically-defined Alzheimer's disease.
Aumont E, Tremblay C, Levert S, Bennett DA, Calon F, Leclerc N
Frontiers in aging neuroscience. PubMed PMID: 36506473
Published date: 2022
Using a Warm Hand-Off Approach to Enroll African American Caregivers in a Multi-Site Clinical Trial: The Handshake Protocol.
Epps F, Brewster G, Phillips JS, Nash R, Shah RC, Hepburn K
Journal of applied gerontology : the official journal of the Southern Gerontological Society 41 (1):142-147. PubMed PMID: 33567942
Published date: 2022 01
APOE4 Allele, Sex, and Dementia Risk in Parkinson's Disease: Lessons From a Longitudinal Cohort.
Umeh CC, Mahajan A, Mihailovic A, Pontone GM
Journal of geriatric psychiatry and neurology 35 (6):8919887211060019. PubMed PMID: 34958617
Published date: 2021 Dec 27
Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias.
Yu L, Boyle PA, Wingo AP, Yang J, Wang T, Buchman AS, Wingo TS, Seyfried NT, Levey AI, De Jager PL, Schneider JA, Bennett DA
Neurology 98 (10):e1031-e1039. PubMed PMID: 34937778
Published date: 2021 Dec 22
Whole genome sequencing-based copy number variations reveal novel pathways and targets in Alzheimer's disease.
Ming C, Wang M, Wang Q, Neff R, Wang E, Shen Q, Reddy JS, Wang X, Allen M, Ertekin-Taner N, De Jager PL, Bennett DA, Haroutunian V, Schadt E, Zhang B
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (10):1846-1867. PubMed PMID: 34918867
Published date: 2021 Dec 17
Identification Of Dementia In Recent Medicare Claims Data, Compared To Rigorous Clinical Assessments.
Grodstein F, Chang CH, Capuano AW, Power MC, Marquez DX, Barnes LL, Bennett DA, James BD, Bynum JPW
The journals of gerontology. Series A, Biological sciences and medical sciences 77 (6):1272-1278. PubMed PMID: 34919685
Published date: 2021 Dec 17
Establishing a framework for gathering structural and social determinants of health in Alzheimer's Disease Research Centers.
Stites SD, Midgett S, Mechanic-Hamilton D, Zuelsdorff M, Glover CM, Marquez DX, Balls-Berry JE, Streitz ML, Babulal G, Trani JF, Henderson JN, Barnes LL, Karlawish J, Wolk DA
The Gerontologist 62 (5):694-703. PubMed PMID: 34919705
Published date: 2021 Dec 17
Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease.
Harerimana NV, Liu Y, Gerasimov ES, Duong D, Beach TG, Reiman EM, Schneider JA, Boyle P, Lori A, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Wingo TS, Wingo AP
Biological psychiatry 92 (1):25-33. PubMed PMID: 35177243
Published date: 2021 Dec 16
The power of genetic diversity in genome-wide association studies of lipids.
Graham SE, Clarke SL, Wu KH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I, Vedantam S, Winkler TW, Locke AE, Marouli E, Hwang MY, Han S, Narita A, Chou dhury A, Bentley AR, Ekoru K, Verma A, Trivedi B, Martin HC, Hunt KA, Hui Q, Klarin D, Zhu X, Thorleifsson G, Helgadottir A, Gudbjartsson DF, Holm H, Olafsson I, Akiyama M, Sakaue S, Terao C, Kanai M, Zhou W, Brumpton BM, Rasheed H, Ruotsalainen SE, Havulinna AS, Veturi Y, Feng Q, Rosenthal EA, Lingren T, Pacheco JA, Pendergrass SA, Haessler J, Giulianini F, Bradford Y, Miller JE, Campbell A, Lin K, Millwood IY, Hindy G, Rasheed A, Faul JD, Zhao W, Weir DR, Turman C, Huang H, Graff M, Mahajan A, Brown MR, Zhang W, Yu K, Schmidt EM, Pandit A, Gustafsson S, Yin X, Luan J, Zhao JH, Matsuda F, Jang HM, Yoon K, Medina-Gomez C, Pitsillides A, Hottenga JJ, Willemsen G, Wood AR, Ji Y, Gao Z, Haworth S, Mitchell RE, Chai JF, Aadahl M, Yao J, Manichaikul A, Warren HR, Ramirez J, Bork-Jensen J, Krhus LL, Goel A, Sabater-Lleal M, Noordam R, Sidore C, Fiorillo E, McDaid AF, Marques-Vidal P, Wielscher M, Tromp et S, Sattar N, Mllehave LT, Thuesen BH, Munz M, Zeng L, Huang J, Yang B, Poveda A, Kurbasic A, Lamina C, Forer L, Scholz M, Galesloot TE, Bradfield JP, Daw EW, Zmuda JM, Mitchell JS, Fuchsberger C, Christensen H, Brody JA, Feitosa MF, Wojczynski MK, Preuss M, Mangino M, Christofidou P, Verweij N, Benjamins JW, Engmann J, Kember RL, Slieker RC, Lo KS, Zilhao NR, Le P, Kleber ME, Delgado GE, Huo S, Ikeda DD, Iha H, Yang J, Liu J, Leonard HL, Marten J, Schmidt B, Arendt M, Smyth LJ, Caadas-Garre M, Wang C, Nakatochi M, Wong A, Hutri-Khnen N, Sim X, Xia R, Huerta-Chagoya A, Fernandez-Lopez JC, Lyssenko V, Ahmed M, Jackson AU, Irvin MR, Oldmeadow C, Kim HN, Ryu S, Timmers PRHJ, Arbeeva L, Dorajoo R, Lange LA, Chai X, Prasad G, Lors-Motta L, Pauper M, Long J, Li X, Theusch E, Takeuchi F, Spracklen CN, Loukola A, Bollepalli S, Warner SC, Wang YX, Wei WB, Nutile T, Ruggiero D, Sung YJ, Hung YJ, Chen S, Liu F, Yang J, Kentistou KA, Gorski M, Brumat M, Meidtner K, Bielak LF, Smith JA, Hebbar P, Farmaki AE, Hofer E, Lin M, Xue C, Zhang J, Concas MP, Vaccargiu S, van der Most PJ, Pitknen N, Cade BE, Lee J, van der Laan SW, Chitrala KN, Weiss S, Zimmermann ME, Lee JY, Choi HS, Nethander M, Freitag-Wolf S, Southam L, Rayner NW, Wang CA, Lin SY, Wang JS, Couture C, Lyytikinen LP, Nikus K, Cuellar-Partida G, Vestergaard H, Hildalg o B, Giannakopoulou O, Cai Q, Obura MO, van Setten J, Li X, Schwander K, Terzikhan N, Shin JH, Jackson RD, Reiner AP, Martin LW, Chen Z, Li L, Highland HM, Young KL, Kawaguchi T, Thiery J, Bis JC, Nadkarni GN, Launer LJ, Li H, Nalls MA, Raitakari OT, Ichihara S, Wild SH, Nelson CP, Campbell H, Jger S, Nabika T, Al-Mulla F, Niinikoski H, Braund PS, Kolcic I, Kovacs P, Giardoglou T, Katsuya T, Bhatti KF, de Kleijn D, de Borst GJ, Kim EK, Adams HHH, Ikram MA, Zhu X, Asselbergs FW, Kraaijeveld AO, Beulens JWJ, Shu XO, Rallidis LS, Pedersen O, Hansen T, Mitchell P, Hewitt AW, Khnen M, Prusse L, Bouchard C, Tnjes A, Chen YI, Pennell CE, Mori TA, Lieb W, Franke A, Ohlsson C, Mellstrm D, Cho YS, Lee H, Yuan JM, Koh WP, Rhee SY, Woo JT, Heid IM, Stark KJ, Vlzke H, Homuth G, Evans MK, Zonderman AB, Polasek O, Pasterkamp G, Hoefer IE, Redline S, Pahkala K, Oldehinkel AJ, Snieder H, Biino G, Schmidt R, Schmidt H, Chen YE, Bandinelli S, Dedoussis G, Thanaraj TA, Kardia SLR, Kato N, Schulze MB, Girotto G, Jung B, Bger CA, Joshi PK, Bennett DA, De Jager PL, Lu X, Mamakou V, Brown M, Caulfield MJ, Munroe PB, Guo X, Ciullo M, Jonas JB, Samani NJ, Kaprio J, Pajukanta P, Adair LS, Bechayda SA, de Silva HJ, Wickremasinghe AR, Krauss RM, Wu JY, Zheng W, den Hollander AI, Bharadwaj D, Correa A, Wilson JG, Lind L, Heng CK, Nelson AE, Golightly YM, Wilson JF, Penninx B, Kim HL, Attia J, Scott RJ, Rao DC, Arnett DK, Walker M, Koistinen HA, Chandak GR, Yajnik CS, Mercader JM, Tusi-Luna T, Aguilar-Salinas CA, Villalpando CG, Orozco L, Fornage M, Tai ES, van Dam RM, Lehtimki T, Chaturvedi N, Yokota M, Liu J, Reilly DF, McKnight AJ, Kee F, Jckel KH, McCarthy MI, Palmer CNA, Vitart V, Hayward C, Simonsick E, van Duijn CM, Lu F, Qu J, Hishigaki H, Lin X, Mrz W, Parra EJ, Cruz M, Gudnason V, Tardif JC, Lettre G, 't Hart LM, Elders PJM, Damrauer SM, Kumari M, Kivimaki M, van der Harst P, Spector TD, Loos RJF, Province MA, Psaty BM, Brandslund I, Pramstaller PP, Christensen K, Ripatti S, Widn E, Hakonarson H, Grant SFA, Kiemeney LALM, de Graaf J, Loeffler M, Kronenberg F, Gu D, Erdmann J, Schunkert H, Franks PW, Linneberg A, Jukema JW, Khera AV, Mnnikk M, Jarvelin MR, Kutalik Z, Cucca F, Mook-Kanamori DO, van Dijk KW, Watkins H, Strachan DP, Grarup N, Sever P, Poulter N, Rotter JI, Dantoft TM, Karpe F, Neville MJ, Timpson NJ, Cheng CY, Wong TY, Khor CC, Sabanayagam C, Peters A, Gieger C, Hattersley AT, Pedersen NL, Magnusson PKE, Boomsma DI, de Geus EJC, Cupples LA, van Meurs JBJ, Ghanbari M, Gordon-Larsen P, Huang W, Kim YJ, Tabara Y, Wareham NJ, Langenberg C, Zeggini E, Kuusisto J, Laakso M, Ingelsson E, Abecasis G, Chambers JC, Kooner JS, de Vries PS, Morrison AC, North KE, Daviglus M, Kraft P, Martin NG, Whitfield JB, Abbas S, Saleheen D, Walters RG, Holmes MV, Black C, Smith BH, Justice AE, Baras A, Buring JE, Ridker PM, Chasman DI, Kooperberg C, Wei WQ, Jarvik GP, Namjou B, Hayes MG, Ritchie MD, Jousilahti P, Salomaa V, Hveem K, svold BO, Kubo M, Kamatani Y, Okada Y, Murakami Y, Thorsteinsdottir U, Stefansson K, Ho YL, Lynch JA, Rader DJ, Tsao PS, Chang KM, Cho K, O'Donnell CJ, Gaziano JM, Wilson P, Rotimi CN, Hazelhurst S, Ramsay M, Trembath RC, van Heel DA, Tamiya G, Yamamoto M, Kim BJ, Mohlke KL, Frayling TM, Hirschhorn JN, Kathiresan S, Boehnke M, Natarajan P, Peloso GM, Brown CD, Morris AP, Assimes TL, Deloukas P, Sun YV, Willer CJ
Nature 600 (7890):675-679. PubMed PMID: 34887591
Published date: 2021 Dec 09
Integration of GWAS and brain transcriptomic analyses in a multiethnic sample of 35,245 older adults identifies DCDC2 gene as predictor of episodic memory maintenance.
Gao Y, Felsky D, Reyes-Dumeyer D, Sariya S, Rentera MA, Ma Y, Klein HU, Cosentino S, De Jager PL, Bennett DA, Brickman AM, Schellenberg GD, Mayeux R, Barral S
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (10):1797-1811. PubMed PMID: 34873813
Published date: 2021 Dec 07
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology.
Dehkordi SK, Walker J, Sah E, Bennett E, Atrian F, Frost B, Woost B, Bennett RE, Orr TC, Zhou Y, Andhey PS, Colonna M, Sudmant PH, Xu P, Wang M, Zhang B, Zare H, Orr ME
Nature aging 1 (12):1107-1116. PubMed PMID: 35531351
Published date: 2021 Dec
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
Horgusluoglu E, Neff R, Song WM, Wang M, Wang Q, Arnold M, Krumsiek J, Galindo-Prieto B, Ming C, Nho K, Kastenmller G, Han X, Baillie R, Zeng Q, Andrews S, Cheng H, Hao K, Goate A, Bennett DA, Saykin AJ, Kaddurah-Daouk R, Zhang B
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (6):1260-1278. PubMed PMID: 34757660
Published date: 2021 Nov 10
Brain insulin signaling and cerebrovascular disease in human postmortem brain.
Arvanitakis Z, Capuano AW, Wang HY, Schneider JA, Kapasi A, Bennett DA, Ahima RS, Arnold SE
Acta neuropathologica communications 9 (1):71. PubMed PMID: 33858515
Published date: 20 21 04 15
Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer's disease brain.
Klein HU, Trumpff C, Yang HS, Lee AJ, Picard M, Bennett DA, De Jager PL
Molecular neurodegeneration 16 (1):75. PubMed PMID: 34742335
Published date: 2021 11 06
Cascading epigenomic analysis for identifying disease genes from the regulatory landscape of GWAS variants.
Ng B, Casazza W, Kim NH, Wang C, Farhadi F, Tasaki S, Bennett DA, De Jager PL, Gaiteri C, Mostafavi S
PLoS genetics 17 (11):e1009918. PubMed PMID: 34807913
Published date: 2021 11
Longitudinal Cognitive Profiles by Anxiety and Depressive Symptoms in American Older Adults With Subjective Cognitive Decline.
Ahn S, Mathiason MA, Yu F
Journal of nursing scholarship : an official publication of Sigma Theta Tau International Honor Society of Nursing 53 (6):698-708. PubMed PMID: 34342395
Published date: 2021 11
Brain -amyloid links the association of change in BMI with cognitive decline in community-dwelling older adults.
Buchman AS, Capuano AW, VanderHorst V, Wilson RS, Oveisgharan S, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 78 (2):277-285. PubMed PMID: 34679171
Published date: 2021 Oct 22
Reducing Your Risk of Alzheimer's Dementia: Building a Better Brain as We Age.
Bennett DA
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 36 (7):1257-1265. PubMed PMID: 34651647
Published date: 2021 Oct 13
Unobtrusive Sensing Technology Detects Ecologically Valid Spatiotemporal Patterns of Daily Routines Distinctive to Persons with Mild Cognitive Impairment.
Wu CY, Dodge HH, Gothard S, Mattek N, Wright K, Barnes LL, Silbert LC, Lim MM, Kaye JA, Beattie Z
The journals of gerontology. Series A, Biological sciences and medical sciences 77 (10):2077-2084. PubMed PMID: 34608939
Published date: 2021 Oct 05
BMI1 is associated with CS8F amyloid- and rates of cognitive decline in Alzheimer's disease.
Kim JP, Kim BH, Bice PJ, Seo SW, Bennett DA, Saykin AJ, Nho K
Alzheimer's research & therapy 13 (1):164. PubMed PMID: 34610832
Published date: 2021 10 05
Inhibitory Fc Receptor and Paired Immunoglobulin Type 2 Receptor Alpha Genotypes in Alzheimer's Disease.
Pandey JP, Namboodiri AM, Nietert PJ, Barnes LL, Bennett DA
Journal of Alzheimer's disease : JAD 84 (3):965-968. PubMed PMID: 34602489
Published date: 2021 Sep 30
The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer's dementia in older persons.
Agrawal S, Yu L, Nag S, Arfanakis K, Barnes LL, Bennett DA, Schneider JA
Acta neuropathologica communications 9 (1):156. PubMed PMID: 34563269
Published date: 2021 09 25
Examining racial disparities in the diagnosis of mild cognitive impairment.
Kiselica AM, Johnson E, Lewis KR, Trout K
Applied neuropsychology. Adult 30 (6):1-8. PubMed PMID: 34554020
Published date: 2021 Sep 23
Is comprehensiveness critical? Comparing short and long format cognitive assessments in preclinical Alzheimer disease.
Hassenstab J, Nicosia J, LaRose M, Aschenbrenner AJ, Gordon BA, Benzinger TLS, Xiong C, Morris JC
Alzheimer's research & therapy 13 (1):153. PubMed PMID: 34517889
Published date: 2021 09 13
Epigenomic features related to microglia are associated with attenuated effect of APOE 4 on Alzheimer's disease risk in humans.
Ma Y, Yu L, Olah M, Smith R, Oatman SR, Allen M, Pishva E, Zhang B, Menon V, Ertekin-Taner N, Lunnon K, Bennett DA, Klein HU, De Jager PL
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 18 (4):688-699. PubMed PMID: 34482628
Published date: 2021 Sep 05
Leukotriene receptor antagonist use and cognitive decline in normal cognition, mild cognitive impairment, and Alzheimer's dementia.
Xiong LY, Ouk M, Wu CY, Rabin JS, Lanctt KL, Herrmann N, Black SE, Edwards JD, Sward fager W
Alzheimer's research & therapy 13 (1):147. PubMed PMID: 34479635
Published date: 2021 09 03
The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes.
Grodstein F, Lemos B, Yu L, Klein HU, Iatrou A, Buchman AS, Shireby GL, Mill J, Schneider JA, De Jager PL, Bennett DA
Neurobiology of disease. PubMed PMID: 34153464
Published date: 2021 Sep
Depression and Increased Risk of Alzheimer's Dementia: Longitudinal Analyses of Modifiable Risk and Sex-Related Factors.
Kim D, Wang R, Kiss A, Bronskill SE, Lanctot KL, Herrmann N, Gallagher D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 29 (9):917-926. PubMed PMID: 33455858
Published date: 2021 09
Association of Lewy Bodies With Age-Related Clinical Characteristics in Black and White Decedents.
Nag S, Barnes LL, Yu L, Buchman AS, Bennett DA, Schneider JA, Wilson RS
Neurology 97 (8):e825-e835. PubMed PMID: 34088871
Published date: 2021 08 24
Sex-Specific Association of the X Chromosome With Cognitive Change and Tau Pathology in Aging and Alzheimer Disease.
Davis EJ, Solsberg CW, White CC, Miones-Moyano E, Sirota M, Chibnik L, Bennett DA, De Jager PL, Yokoyama JS, Dubal DB
JAMA neurology 78 (10):1249-1254. PubMed PMID: 34424272
Published date: 2021 Aug 23
Bootstrap approach for meta-synthesis of MRI findings from multiple scanners.
Kim N, Arfanakis K, Leurgans SE, Yang J, Fleischman DA, Han SD, Aggarwal NT, Lamar M, Yu L, Poole VN, Bennett DA, Barnes LL
Journal of neuroscience methods. PubMed PMID: 34052288
Published date: 2021 08 01
Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice.
Jeong A, Cheng S, Zhong R, Bennett DA, Berg MO, Li L
Acta neuropathologica communications 9 (1):129. PubMed PMID: 34315531
Published date: 2021 Jul 27
A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer's disease.
Huang Y, Sun X, Jiang H, Yu S, Robins C, Armstrong MJ, Li R, Mei Z, Shi X, Gerasimov ES, De Jager PL, Bennett DA, Wingo AP, Jin P, Wingo TS, Qin ZS
Nature communications 12 (1):4472. PubMed PMID: 34294691
Published date: 2021 Jul 22
Cognitive and brain cytokine profile of non-demented individuals with cerebral amyloid-beta deposition.
Flores-Aguilar L, Iulita MF, Orciani C, Tanna N, Yang J, Bennett DA, Cuello AC
Journal of neuroinflammation 18 (1):147. PubMed PMID: 34218796
Published date: 2021 Jul 04
A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex.
Smith RG, Pishva E, Shireby G, Smith AR, Roubroeks JAY, Ha nnon E, Wheildon G, Mastroeni D, Gasparoni G, Riemenschneider M, Giese A, Sharp AJ, Schalkwyk L, Haroutunian V, Viechtbauer W, van den Hove DLA, Weedon M, Brokaw D, Francis PT, Thomas AJ, Love S, Morgan K, Walter J, Coleman PD, Bennett DA, De Jager PL, Mill J, Lunnon K
Nature communications 12 (1):3517. PubMed PMID: 34112773
Published date: 2021 Jun 10
Abnormal brain cholesterol homeostasis in Alzheimer's disease-a targeted metabolomic and transcriptomic study.
Varma VR, Bra Lleci H, Oommen AM, Varma S, Blackshear CT, Griswold ME, An Y, Roberts JA, O'Brien R, Pletnikova O, Troncoso JC, Bennett DA, akr T, Legido-Quigley C, Thambisetty M
NPJ aging and mechanisms of disease 7 (1):11. PubMed PMID: 34075056
Published date: 2021 Jun 01
A coordinated analysis of the associations among personality traits, cognitive decline, and dementia in older adulthood.
Graham EK, James BD, Jackson KL, Willroth EC, Luo J, Beam CR, Pedersen NL, Reynolds CA, Katz M, Lipton RB, Boyle P, Wilson R, Bennett DA, Mroczek DK
Journal of research in personality. PubMed PMID: 34083845
Published date: 2021 Jun
The "cognitive clock": A novel indicator of brain health.
Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Beck T, Rajan KB, Evans D, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 17 (12):1923-1937. PubMed PMID: 34060702
Published date: 2021 Jun 01
Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease.
Zalocusky KA, Najm R, Taubes AL, Hao Y, Yoon SY, Koutsodendris N, Nelson MR, Rao A, Bennett DA, Bant J, Amornkul DJ, Xu Q, An A, Cisne-Thomson O, Huang Y
Nature neuroscience 24 (6):786-798. PubMed PMID: 33958804
Published date: 2021 Jun
Association of Hemoglobin A1C With TDP-43 Pathology in Community-Based Elders.
Oveisgharan S, Capuano AW, Nag S, Agrawal S, Barnes LL, Bennett DA, Arvanitakis Z, Schneider JA
Neurology 96 (22):e2694-e2703. PubMed PMID: 33853892
Published date: 2021 May 31
Cortical proteins may provide motor resilience in older adults.
Buchman AS, Yu L, Oveisgharan S, Petyuk VA, Tasaki S, Gaiteri C, Wilson RS, Grodstein F, Schneider JA, Klein HU, De Jager PL, Bennett DA
Scientific reports 11 (1):11311. PubMed PMID: 34050212
Published date: 2021 May 28
A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
Vattathil SM, Liu Y, Harerimana NV, Lori A, Gerasimov ES, Beach TG, Reiman EM, De Jager PL, Schneider JA, Bennett DA, Seyfried NT, Levey AI, Wingo AP, Wingo TS
Genes. PubMed PMID: 34073619
Published date: 2021 May 26
Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study.
Varma VR, Wang Y, An Y, Varma S, Bilgel M, Doshi J, Legido-Quigley C, Delgado JC, Oommen AM, Roberts JA, Wong DF, Davatzikos C, Resnick SM, Troncoso JC, Pletnikova O, O'Brien R, Hak E, Baak BN, Pfeiffer R, Baloni P, Mohmoudiandehkordi S, Nho K, Kaddurah-D
PLoS medicine 18 (5):e1003615. PubMed PMID: 34043628
Published date: 2021 May
Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons.
Agrawal S, Yu L, Kapasi A, James BD, Arfanakis K, Barnes LL, Bennett DA, Nag S, Schneider JA
Brain pathology (Zurich, Switzerland) 31 (3):e12939. PubMed PMID: 33624322
Published date: 2021 May
Proteomic Profiling of the Substantia Nigra to Identify Determinants of Lewy Body Pathology and Dopaminergic Neuronal Loss.
Petyuk VA, Yu L, Olson HM, Yu F, Clair G, Qian WJ, Shulman JM, Bennett DA
Journal of proteome research 20 (5):2266-2282. PubMed PMID: 33900085
Published date: 2021 Apr 26
Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.
Carlyle BC, Kandigian SE, Kreuzer J, Das S, Trombetta BA, Kuo Y, Bennett DA, Schneider JA, Petyuk VA, Kitchen RR, Morris R, Nairn AC, Hyman BT, Haas W, Arnold SE
Neurobiology of aging. PubMed PMID: 34052751
Published date: 2021 Apr 24
Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4.
Wang S, Li B, Solomon V, Fonteh A, Rapoport SI, Bennett DA, Arvanitakis Z, Chui HC, Miller C, Sullivan PM, Wang HY, Yassine HN
Molecular neurodegeneration 16 (1):26. PubMed PMID: 33863362
Published date: 2021 04 16
Enhancing Top-Down Proteomics of Brain Tissue with FAIMS.
Fulcher JM, Makaju A, Moore RJ, Zhou M, Bennett DA, De Jager PL, Qian WJ, Paa-Toli L, Petyuk VA
Journal of proteome research 20 (5):2780-2795. PubMed PMID: 33856812
Published date: 2021 Apr 15
Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
Wingo TS, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Lori A, Kim PJ, Ressler KJ, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, Levey AI, Wingo AP
Nature neuroscience 24 (6):810-817. PubMed PMID: 33846625
Published date: 2021 Apr 12
Novel Variance-Component TWAS method for studying complex human diseases with applications to Alzheimer's dementia.
Tang S, Buchman AS, De Jager PL, Bennett DA, Epstein MP, Yang J
PLoS genetics 17 (4):e1009482. PubMed PMID: 33798195
Published date: 2021 Apr 02
Interactive Effects of HLA and GM Alleles on the Development of Alzheimer Disease.
Pandey JP, Nietert PJ, Kothera RT, Barnes LL, Bennett DA
Neurology. Genetics 7 (2):e565. PubMed PMID: 33898740
Published date: 2021 Apr
Risk factors for the progression of motoric cognitive risk syndrome to dementia: retrospective cohort analysis of two populations.
Meiner Z, Ayers E, Bennett DA, Wang C, Verghese J
European journal of neurology 28 (6):1859-1867. PubMed PMID: 33780585
Published date: 2021 Mar 29
To what degree is late life cognitive decline driven by age-relatedneuropathologies?
Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Bennett DA
Brain : a journal of neurology 144 (7):2166-2175. PubMed PMID: 33742668
Published date: 2021 Mar 20
Genome-wide epistasis analysis for Alzheimer's disease and implications for genetic risk prediction.
Wang H, Bennett DA, De Jager PL, Zhang QY, Zhang HY
Alzheimer's research & therapy 13 (1):55. PubMed PMID: 33663605
Published date: 2021 Mar 04
Exome-wide age-of-onset analysis reveals exonic variants in ERN1 and SPPL2C associated with Alzheimer's disease.
He L, Loika Y, Park Y, Bennett DA, Kellis M, Kulminski AM
Translational psychiatry 11 (1):146. PubMed PMID: 33637690
Published date: 2021 Feb 26
Frequency of Parkinsonism and Parkinson Disease in African Americans in the Chicago Community.
Bailey M, Shulman LM, Ryan D, Ouyang B, Shulman JM, Buchman AS, Bennett DA, Barnes LL, Hall DA
The journals of gerontology. Series A, Biological sciences and medical sciences 76 (7):1340-1345. PubMed PMID: 33631006
Published date: 2021 Feb 25
Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer's disease.
De Jager CH, White CC, Bennett DA, Ma Y
Translational psychiatry 11 (1):139. PubMed PMID: 33627625
Published date: 2021 Feb 24
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture.
Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, Hernandez DG, Blauwendraat C, Stone DJ, Eicher J, Parkkinen L, Ansorge O, Cla
Nature genetics 53 (3):294-303. PubMed PMID: 33589841
Published date: 2021 Feb 15
TOMM40-APOE haplotypes are associated with cognitive decline in non-demented Blacks.
Deters KD, Mormino EC, Yu L, Lutz MW, Bennett DA, Barnes LL
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 17 (8):1287-1296. PubMed PMID: 33580752
Published date: 2021 Feb 13
A (Amyloid Beta) and Tau Tangle Pathology Modifies the Association Between Small Vessel Disease and Cortical Microinfarcts.
Kapasi A, Leurgans SE, Arvanitakis Z, Barnes LL, Bennett DA, Schneider JA
Stroke 52 (3):STROKEAHA120031073. PubMed PMID: 33567873
Published date: 2021 Feb 11
Genetic control of the human brain proteome.
Robins C, Liu Y, Fan W, Duong DM, Meigs J, Harerimana NV, Gerasimov ES, Dammer EB, Cutler DJ, Beach TG, Reiman EM, De Jager PL, Bennett DA, Lah JJ, Wingo AP, Levey AI, Seyfried NT, Wingo TS
American journal of human genetics 108 (3):400-410. PubMed PMID: 33571421
Published date: 2021 Feb 08
Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Jones G, Trajanoska K, Santanasto AJ, Stringa N, Kuo CL, Atkins JL, Lewis JR, Duong T, Hong S, Biggs ML, Luan J, Sarnowski C, Lunetta KL, Tanaka T, Wojczynski MK, Cvejkus R, Nethander M, Ghasemi S, Yang J, Zillikens MC, Walter S, Sicinski K, Kague E, Acke
Nature communications 12 (1):654. PubMed PMID: 33510174
Published date: 2021 01 28
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, Levey AI, Wingo TS
Nature genetics 53 (2):143-146. PubMed PMID: 33510477
Published date: 2021 Jan 28
Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.
Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang
JAMA neurology 78 (1):102-113. PubMed PMID: 33074286
Published date: 2021 Jan 01
Associations Between Personality Traits and Cognitive Resilience in Older Adults.
Graham EK, James BD, Jackson KL, Willroth EC, Boyle P, Wilson R, Bennett DA, Mroczek DK
The journals of gerontology. Series B, Psychological sciences and social sciences 76 (1):6-19. PubMed PMID: 32969474
Published date: 2021 Jan 01
Late-Life Vascular Risk Score in Association With Postmortem Cerebrovascular Disease Brain Pathologies.
Oveisgharan S, Yu L, Capuano A, Arvanitakis Z, Barnes LL, Schneider JA, Bennett DA, Buchman AS
Stroke 52 (6):2060-2067. PubMed PMID: 33840227
Published date: 2021 Ju n
Association Between the APOE2/4 Genotype and Alzheimer's Disease and Mild Cognitive Impairment Among African Americans.
Ren D, Lopez OL, Lingler JH, Conley Y
Journal of Alzheimer's disease : JAD 81 (3):943-948. PubMed PMID: 33935088
Published date: 2021
Risk of mild cognitive impairment among older adults in the United States by ethnoracial group.
Perales-Puchalt J, Gauthreaux K, Shaw A, McGee JL, Teylan MA, Chan KCG, Rascovsky K, Kukull WA, Vidoni ED
International psychogeriatrics 33 (1):51-62. PubMed PMID: 31948505
Published date: 2021 01
ARTS: A novel In-vivo classifier of arteriolosclerosis for the older adult brain.
Makkinejad N, Evia AM, Tamhane AA, Javierre-Petit C, Leurgans SE, Lamar M, Barnes LL, Bennett DA, Schneider JA, Arfanakis K
NeuroImage. Clinical. PubMed PMID: 34330087
Published date: 2021
Diverse Motor Performances Are Related to Incident Cognitive Impairment in Community-Dwelling Older Adults.
Beeri MS, Leurgans SE, Bennett DA, Barnes LL, Buchman AS
Frontiers in aging neuroscience. PubMed PMID: 34658835
Published date: 2021
In-Home Mobility Frequency and Stability in Older Adults Living Alone With or Without MCI: Introduction of New Metrics.
Wu CY, Dodge HH, Reynolds C, Barnes LL, Silbert LC, Lim MM, Mattek N, Gothard S, Kaye JA, Beattie Z
Frontiers in digital health. PubMed PMID: 34766104
Published date: 2021
Human Brain and Blood N-Glycome Profiling in Alzheimer's Disease and Alzheimer's Disease-Related Dementias.
Yu L, Huo Z, Yang J, Palma-Gudiel H, Boyle PA, Schneider JA, Bennett DA, Zhao J
Frontiers in aging neuroscience. PubMed PMID: 34776937
Published date: 2021
Cognitive screening with functional assessment improves diagnostic accuracy and attenuates bias.
Gonzlez DA, Gonzales MM, Jennette KJ, Soble JR, Fongang B
Alzheimer's & dementia (Amsterdam, Netherlands) 13 (1):e12250. PubMed PMID: 34934799
Published date: 2021
Prevalent, persistent, and impairing: Longitudinal course and impact of apathy in Alzheimer's disease.
Grossman HT, Sano M, Aloysi A, Elder GA, Neugroschl J, Schimming C, Soleimani L, Zhu CW
Alzheimer's & dementia (Amsterdam, Netherlands) 13 (1):e12169. PubMed PMID: 35141391
Published date: 2021
Cerebral small vessel disease genomics and its implications across the lifespan.
Sargurupremraj M, Suzuki H, Jian X, Sarnowski C, Evans TE, Bis JC, Eiriksdottir G, Sakaue S, Terzikhan N, Habes M, Zhao W, Armstrong NJ, Hofer E, Yanek LR, Hagenaars SP, Kumar RB, van den Ak ker EB, McWhirter RE, Trompet S, Mishra A, Saba Y, Satizabal CL,
Nature communications 11 (1):6285. PubMed PMID: 33293549
Published date: 2020 12 08
EPIGENOMIC FEATURES RELATED TO MICROGLIA ARE ASSOCIATED WITH ATTENUATED EFFECT OF APOE 4 ON ALZHEIMER'S DISEASE RISK IN HUMANS.
Ma Y, Yu L, Olah M, Smith R, Oatman SR, Allen M, Pishva E, Zhang B, Menon V, Ertekin-Taner N, Lunnon K, Bennett DA, Klein HU, De Jager PL
Alzheimer's & dementia : the journal of the Alzheimer's Association 16 (Suppl 2):102768. PubMed PMID: 34393677
Published date: 2020 12
Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer's disease.
Zhang L, Silva TC, Young JI, Gomez L, Schmidt MA, Hamilton-Nelson KL, Kunkle BW, Chen X, Martin ER, Wang L
Nature communications 11 (1):6114. PubMed PMID: 33257653
Published date: 2020 11 30
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease.
Olah M, Menon V, Habib N, Taga MF, Ma Y, Yung CJ, Cimpean M, Khairallah A, Coronas-Samano G, Sankowski R, Grn D, Kroshilina AA, Dionne D, Sarkis RA, Cosgrove GR, Helgager J, Golden JA, Pennell PB, Prinz M, Vonsattel JPG, Teich AF, Schneider JA, Bennett DA
Nature communications 11 (1):6129. PubMed PMID: 33257666
Published date: 2020 11 30
Association of Low Systolic Blood Pressure with Postmortem Amyloid- and Tau.
Oveisgharan S, Capuano AW, Kapasi A, Buchman AS, Schneider JA, Bennett DA, Arvanitakis Z
Journal of Alzheimer's disease : JAD 78 (4):1755-1764. PubMed PMID: 33185594
Published date: 2020 Nov 06
The Relation of Diabetes to Memory Function.
Arvanitakis Z, Tatavarthy M, Bennett DA
Current neurology and neuroscience reports 20 (12):64. PubMed PMID: 33150490
Published date: 2020 Nov 05
A new role for matrix metalloproteinase-3 in the NGF metabolic pathway: Proteolysis of mature NGF and sex-specific differences in the continuum of Alzheimer's pathology.
Pentz R, Iulita MF, Mikutra-Cencora M, Ducatenzeiler A, Bennett DA, Cuello AC
Neurobiology of disease. PubMed PMID: 33130223
Published date: 2020 Oct 29
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostaf avi S, Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM
Scientific data 7 (1):340. PubMed PMID: 33046718
Published date: 2020 Oct 12
Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy.
Yu L, Schneider JA, Kapasi A, Bennett DA, Boyle PA
Alzheimer disease and associated disorders 34 (4):299-305. PubMed PMID: 32452861
Published date: 2020 Oct-Dec
Bayesian Genome-wide TWAS Method to Leverage both cis- and trans-eQTL Information through Summary Statistics.
Luningham JM, Chen J, Tang S, De Jager PL, Bennett DA, Buchman AS, Yang J
American journal of human genetics 107 (4):714-726. PubMed PMID: 32961112
Published date: 2020 Sep 10
Cross-Species Analyses Identify Dlgap2 as a Regulator of Age-Related Cognitive Decline and Alzheimer's Dementia.
Ouellette AR, Neuner SM, Dumitrescu L, Anderson LC, Gatti DM, Mahoney ER, Bubier JA, Churchill G, Peters L, Huentelman MJ, Herskowitz JH, Yang HS, Smith AN, Reitz C, Kunkle BW, White CC, De Jager PL, Schneider JA, Bennett DA, Seyfried NT, Chesler EJ, Hada
Cell reports 32 (9):108091. PubMed PMID: 32877673
Published date: 2020 Sep 01
Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults.
Javierre-Petit C, Schneider JA, Kapasi A, Makkinejad N, Tamhane AA, Leurgans SE, Mehta RI, Barnes LL, Bennett DA, Arfanakis K
Stroke 51 (9):2825-2833. PubMed PMID: 32757750
Published date: 2020 09
Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function.
Arvanitakis Z, Wang HY, Capuano AW, Khan A, Tab B, Anokye-Danso F, Schneider JA, Bennett DA, Ahima RS, Arnold SE
Annals of neurology 88 (3):513-525. PubMed PMID: 32557841
Published date: 2020 09
Extending AD biomarker studies into the Hispanic community.
Bennett DA, Knopman DS
Neurology 95 (15):665-666. PubMed PMID: 32847949
Published date: 2020 Aug 26
A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease.
Davis EJ, Broestl L, Abdulai-Saiku S, Worden K, Bonham LW, Miones-Moyano E, Moreno AJ, Wang D, Chang K, Williams G, Garay BI, Lobach I, Devidze N, Kim D, Anderson-Bergman C, Yu GQ, White CC, Harris JA, Miller BL, Bennett DA, Arnold AP, De Jager PL, Palop
Science translational medicine. PubMed PMID: 32848093
Published date: 2020 Aug 26
Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218.
Jurkiewicz M, Moser D, Koller A, Yu L, Chen EI, Be nnett DA, Canli T
Translational psychiatry 10 (1):297. PubMed PMID: 32839459
Published date: 2020 Aug 24
Peripheral serum metabolomic profiles inform central cognitive impairment.
Wang J, Wei R, Xie G, Arnold M, Kueider-Paisley A, Louie G, Mahmoudian Dehkordi S, Blach C, Baillie R, Han X, De Jager PL, Bennett DA, Kaddurah-Daouk R, Jia W
Scientific reports 10 (1):14059. PubMed PMID: 32820198
Published date: 2020 Aug 20
Brain pathologies are associated with both the rate and variability of declining motor function in older adults.
Buchman AS, Wang T, Yu L, Leurgans SE, Schneider JA, Bennett DA
Acta neuropathologica 140 (4):587-589. PubMed PMID: 32803349
Published date: 2020 Aug 14
Limbic-predominant age-related TDP-43 encephalopathy in black and white decedents.
Nag S, Barnes LL, Yu L, Wilson RS, Bennett DA, Schneider JA
Neurology 95 (15):e2056-e2064. PubMed PMID: 32759188
Published date: 2020 Aug 05
Limbic-Predominant Age-Related TDP-43 Encephalopathy (LATE), ADNC Pathology, and Cognitive Decline in Aging.
Kapasi A, Yu L, Boyle PA, Barnes LL, Bennett DA, Schneider JA
Neurology 95 (14):e1951-e1962. PubMed PMID: 32753441
Published date: 2020 Aug 04
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression.
Patrick E, Taga M, Ergun A, Ng B, Casazza W, Cimpean M, Yung C, Schneider JA, Bennett DA, Ga iteri C, De Jager PL, Bradshaw EM, Mostafavi S
PLoS computational biology 16 (8):e1008120. PubMed PMID: 32804935
Published date: 2020 Aug
Genetic variants and functional pathways associated with resilience to Alzheimer's disease.
Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittsc huh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, Mormino E, Ya ng HS, Harrison T, Hedden T, Nho K, Andrews SJ, Tommet D, Hada
Brain : a journal of neurology 3 (8):2561-2575. PubMed PMID: 32844198
Published date: 2020 Aug 01
Synonymous variants associated with Alzheimer disease in multiplex families.
Tang M, Alaniz ME, Felsky D, Vardarajan B, Reyes-Dumeyer D, Lantigua R, Medrano M, Bennett DA, de Jager PL, Mayeux R, Santa-Maria I, Reitz C
Neurology. Genetics 6 (4):e450. PubMed PMID: 32637632
Published date: 2020 Aug
Association between DNA methylation levels in brain tissue and late-life depression in community-based participants.
H ls A, Robins C, Conneely KN, De Jager PL, Bennett DA, Epstein MP, Wingo TS, Wingo AP
Translational psychiatry 10 (1):262. PubMed PMID: 32733030
Published date: 2020 Jul 30
Alzheimer's disease frequency peaks in the tenth decade and is lower afterwards.
Farfel JM, Yu L, Boyle PA, Leurgans S, Shah RC, Schneider JA, Bennett DA
Acta neuropathologica communications 7 (1):104. PubMed PMID: 31269985
Published date: 20 19 07 03
BIN1 protein isoforms are differentially expressed in astrocytes, neurons, and microglia: neuronal and astrocyte BIN1 are implicated in tau pathology.
Taga M, Petyuk VA, White C, Marsh G, Ma Y, Klein HU, Connor SM, Kroshilina A, Yung CJ, Khairallah A, Olah M, Schneider J, Karhohs K, Carpenter AE, Ransohoff R, Bennett DA, Crotti A, Bradshaw EM, De Jager PL
Molecular neurodegeneration 15 (1):44. PubMed PMID: 32727516
Published date: 2020 07 29
Person-specific contributions of brain pathologies to progressive parkinsonism in older adults.
Buchman AS, Yu L, Oveisgharan S, Farfel JM, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 76 (4):615-621. PubMed PMID: 32720690
Published date: 2020 Jul 28
Self-reported experiences of discrimination in older black adults are associated with insula functional connectivity.
Han SD, Lamar M, Fleischman D, Kim N, Bennett DA, Lewis TT, Arfanakis K, Barnes LL
Brain imaging and behavior 15 (4):1718-1727. PubMed PMID: 32720182
Published date: 2020 Jul 27
Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, Martini-Stoica H, Zheng H, Mei H, Zhong X, Kim JW, Dawson VL, Dawson TM, Pao PC, Tsai LH, Hau
Cell reports 32 (2):107908. PubMed PMID: 32668255
Published date: 2020 Jul 14
Deep learning decodes the principles of differential gene expression.
Tasaki S, Gaiteri C, Mostafavi S, Wang Y
Nature machine intelligence 2 (7):376-386. PubMed PMID: 32671330
Published date: 2020 Jul
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease.
Fan CC, Banks SJ, Thompson WK, Chen CH, McEvoy LK, Tan CH, Kukull W, Bennett DA, Farrer LA, Mayeux R, Schellenberg GD, Andreassen OA, Desikan R, Dale AM
Brain : a journal of neurology 143 (7):2272-2280. PubMed PMID: 32591829
Published date: 2020 Jul 01
Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons.
Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA
JAMA psychiatry 77 (11):1172-1180. PubMed PMID: 32609320
Published date: 2020 Jul 01
Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.
Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C, Del-Aguila J, Farrer LA, Mayeux R, Munsie L, Winslow A, Newhouse S, Saykin AJ, Kauwe JSK, Crane PK, Green RC
Alzheimer's & dementia : the journal of the Alzheimer's AssociationREFERENCES 16 (8):1134-1145. PubMed PMID: 32573913
Published date: 2020 Jun 23
Association Between Common Variants in RBFOX1, an RNA-Binding Protein, and Brain Amyloidosis in Early and Preclinical Alzheimer Disease.
Raghavan NS, Dumitrescu L, Mormino E, Mahoney ER, Lee AJ, Gao Y, Bilgel M, Goldstein D, Harrison T, Engelman CD, Saykin AJ, Whelan CD, Liu JZ, Jagust W, Albert M, Johnson SC, Yang HS, Johnson K, Aisen P, Resnick SM, Sperling R, De Jager PL, Schneider J, B
JAMA neurology 16 (8):1134-1145. PubMed PMID: 32568366
Published date: 2020 Jun 22
Walking in the Light: How History of Physical Activity, Sunlight, and Vitamin D Account for Body Fat-A UK Biobank Study.
Klinedinst BS, Meier NF, Larsen B, Wang Y, Yu S, Mochel JP, Le S, Wolf T, Pollpeter A, Pappas C, Wang Q, Allenspach K, Wang L, Russell D, Bennett DA, Willette AA
Obesity (Silver Spring, Md.)References 16 (8):1134-1145. PubMed PMID: 32573118
Published date: 2020 Jun 22
Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
Yang HS, White CC, Klein HU, Yu L, Gaiteri C, Ma Y, Felsky D, Mostafavi S, Petyuk VA, Sperling RA, Ertekin-Taner N, Schneider JA, Bennett DA, De Jager PL
Neuron 107 (3):496-508.e6. PubMed PMID: 32526197
Published date: 2020 Jun 08
The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease.
Pentz R, Iulita MF, Ducatenzeiler A, Bennett DA, Cuello AC
Molecular psychiatry 26 (10):6023-6037. PubMed PMID: 32488129
Published date: 2020 Jun 02
Transcriptomic stratification of late-onset Alzheimer's cases reveals novel genetic modifiers of disease pathology.
Milind N, Preuss C, Haber A, Ananda G, Mukherjee S, John C, Shapley S, Logsdon BA, Crane PK, Carter GW
PLoS genetics 16 (6):e1008775. PubMed PMID: 32492070
Published date: 2020 06
Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH
Nature medicine 26 (6):952-963. PubMed PMID: 32514169
Published date: 2020 Jun
Normative Cognitive Decline in Old Age.
Wilson RS, Wang T, Yu L, Bennett DA, Boyle PA
Annals of neurologyReferences 87 (6):816-829. PubMed PMID: 32144793
Published date: 2020 06
Fragile X Gray Zone Alleles Are Associated With Signs of Parkinsonism and Earlier Death.
Hall DA, Nag S, Ouyang B, Bennett DA, Liu Y, Ali A, Zhou L, Berry-Kravis E
Movement disorders : official journal of the Movement Disorder SocietyReferences 35 (8):1448-1456. PubMed PMID: 32463542
Published date: 2020 May 28
Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, Seyfried NT, Levey AI, Wingo TS
Nature neuroscience 23 (6):696-700. PubMed PMID: 32424284
Published date: 2020 May 18
Tissue Specific Fate of Nanomaterials by Advanced Analytical Imaging Techniques - A Review.
Graham U, Dozier AK, Oberdorster G, Yokel R, Molina RM, Brain JD, Pinto J, Weuve J, Bennett DA
Chemical research in toxicology 33 (5):1145-1162. PubMed PMID: 32349469
Published date: 2020 Apr 30
Genome-wide interaction analysis of pathological hallmarks in Alzheimer's disease.
Wang H, Yang J, Schneider JA, De Jager PL, Bennett DA, Zhang HY
Neurobiology of aging. PubMed PMID: 32450446
Published date: 2020 Apr 29
Physicians and Alzheimer Dementia: Past, Present, and Future.
Shah RC, Bennett DA
Annals of internal medicine 172 (10):695-696. PubMed PMID: 32340036
Published date: 2020 Apr 28
Expression profiling of precuneus layer III cathepsin D-immunopositive pyramidal neurons in mild cognitive impairment and Alzheimer's disease: Evidence for neuronal signaling vulnerability.
He B, Perez SE, Lee SH, Ginsberg SD, Malek-Ahmadi M, Mufson EJ
The Journal of comparative neurologyREFERENCES 528 (16):2748-2766. PubMed PMID: 32323319
Published date: 2020 Apr 22
Corrigendum to brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis [Neurobiology of Aging Volume 86, February 2020, Pages 123-133].
Huo Z, Yu L, Yang J, Zhu Y, Bennett DA, Zhao J
Neurobiology of aging. PubMed PMID: 32312579
Published date: 2020 Apr 18
Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, Reiman EM, Haroutunian V, Wang M, Schadt E, Zhang B, Dickson DW, Ertekin-Taner N, Gold
Nature medicine 26 (5):769-780. PubMed PMID: 32284590
Published date: 2020 Apr 13
Bayesian integrative analysis of epigenomic and transcriptomic data identifies Alzheimer's disease candidate genes and networks.
Klein HU, Sch fer M, Bennett DA, Schwender H, De Jager PL
PLoS computational biology 16 (4):e1007771. PubMed PMID: 32255787
Published date: 2020 Apr
"My Parent's Body Is Sacred": Perspectives From Adult Latino Children About Brain Donation for Alzheimer Disease Research.
Montoya Y, Balbim GM, Glover CM, Marquez DX
Alzheimer disease and associated disorders 35 (1):88-90. PubMed PMID: 32218066
Published date: 2020 Mar 24
Shared Causal Paths underlying Alzheimer's dementia and Type 2 Diabetes.
Hu Z, Jiao R, Wang P, Zhu Y, Zhao J, De Jager P, Bennett DA, Jin L, Xiong M
Scientific reports 10 (1):4107. PubMed PMID: 32139775
Published date: 2020 Mar 05
Sex and APOE 4 genotype modify the Alzheimer's disease serum metabolome.
Arnold M, Nho K, Kueider-Paisley A, Massaro T, Huynh K, Brauner B, MahmoudianDehkordi S, Louie G, Moseley MA, Thompson JW, John-Williams LS, Tenenbaum JD, Blach C, Chang R, Brinton RD, Baillie R, Han X, Trojanowski JQ, Shaw LM, Martins R, Weiner MW, Trush
Nature communications 11 (1):1148. PubMed PMID: 32123170
Published date: 2020 Mar 02
The Factor Structure of Cognitive Functioning in Cognitively Healthy Participants: a Meta-Analysis and Meta-Analysis of Individual Participant Data.
Agelink van Rentergem JA, de Vent NR, Schmand BA, Murre JMJ, Staaks JPC, Huizenga HM
Neuropsychology review 30 (1):51-96. PubMed PMID: 32008158
Published date: 2020 Mar
APOE 4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
Moore AM, Mahoney E, Dumitrescu L, De Jager PL, Koran MEI, Petyuk VA, Robinson RA, Ruderfer DM, Cox NJ, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ
Neurobiology of aging. PubMed PMID: 31791659
Published date: 2020 03
Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease.
Moreno-Rodriguez M, Perez SE, Nadeem M, Malek-Ahmadi M, Mufson EJ
Journal of neuroinflammation 17 (1):58. PubMed PMID: 32066474
Published date: 2020 Feb 17
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
Wingo TS, Yang J, Fan W, Min Canon S, Gerasimov ES, Lori A, Logsdon B, Yao B, Seyfried NT, Lah JJ, Levey AI, Boyle PA, Schneider JA, De Jager PL, Bennett DA, Wingo AP
NPJ genomic medicine 5 (1):6. PubMed PMID: 33542234
Published date: 2020 Feb 06
Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Keene CD, Kamboh MI, Kofler JK, Duque L, Gilbert JR, Gwirtsman H
Nature communications 11 (1):667. PubMed PMID: 32015339
Published date: 2020 Feb 03
Brain mural cell loss in the parietal cortex in alzheimer's disease correlates with cognitive decline and TDP-43 pathology.
Bourassa P, Tremblay C, Schneider JA, Bennett DA, Calon F
Neuropathology and applied neurobiology 46 (5):458-477. PubMed PMID: 31970820
Published date: 2020 Jan 22
Human Herpesvirus 6 Detection in Alzheimer's Disease Cases and Controls across Multiple Cohorts.
Allnutt MA, Johnson K, Bennett DA, Connor SM, Troncoso JC, Pletnikova O, Albert MS, Resnick SM, Scholz SW, De Jager PL, Jacobson S
Neuron 105 (6):1027-1035.e2. PubMed PMID: 31983538
Published date: 2020 Jan 14
Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons.
Yu L, Boyle PA, Dawe RJ, Bennett DA, Arfanakis K, Schneider JA
Neurology 94 (2):e142-e152. PubMed PMID: 31757868
Published date: 2020 Jan 14
Neuropathologic Correlates of White Matter Hyperintensities in a Community-Based Cohort of Older Adults.
Arfanakis K, Evia AM, Leurgans SE, Cardoso LFC, Kulkarni A, Alqam N, Lopes LF, Vieira D, Bennett DA, Schneider JA
Journal of Alzheimer's disease : JAD 73 (1):333-345. PubMed PMID: 31771057
Published date: 2020
Braak Stage, Cerebral Amyloid Angiopathy, and Cognitive Decline in Early Alzheimer's Disease.
Malek-Ahmadi M, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease : JAD 74 (1):189-197. PubMed PMID: 31985469
Published date: 2020
Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices.
Dawe RJ, Yu L, Arfanakis K, Schneider JA, Bennett DA, Boyle PA
Alzheimer's & dementia : the journal of the Alzheimer's Association 16 (1):209-218. PubMed PMID: 31914231
Published date: 2020 Jan
Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
Wingo TS, Yang J, Fan W, Min Canon S, Gerasimov ES, Lori A, Logsdon B, Yao B, Seyfried NT, Lah JJ, Levey AI, Boyle PA, Schneider JA, De Jager PL, Bennett DA, Wingo AP
NPJ genomic medicine. PubMed PMID: 32047652
Published date: 2020
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease.
Zhou Y, Song WM, Andhey PS, Swain A, Levy T, Miller KR, Poliani PL, Cominelli M, Grover S, Gilfillan S, Cella M, Ulland TK, Zaitsev K, Miyashita A, Ikeuchi T, Sainouchi M, Kakita A, Bennett DA, Schneider JA, Nichols MR, Beausoleil SA, Ulrich JD, Holtzman
Nature medicine 26 (1):131-142. PubMed PMID: 31932797
Published date: 2020 Jan
Plasma proteomic signatures predict dementia and cognitive impairment.
Tanaka T, Lavery R, Varma V, Fantoni G, Colpo M, Thambisetty M, Candia J, Resnick SM, Bennett DA, Biancotto A, Bandinelli S, Ferrucci L
Alzheimer's & dementia (New York, N. Y.) 6 (1):e12018. PubMed PMID: 32607407
Published date: 2020
Characteristics of Epigenetic Clocks Across Blood and Brain Tissue in Older Women and Men.
Grodstein F, Lemos B, Yu L, Iatrou A, De Jager PL, Bennett DA
Frontiers in neuroscience. PubMed PMID: 33488342
Published date: 2020
Perceived Impediments to Completed Brain Autopsies Among Diverse Older Adults Who Have Signed a Uniform Anatomical Gift Act for Brain Donation for Clinical Research.
Glover CM, Shah RC, Bennett DA, Wilson RS, Barnes LL
Ethnicity & disease 30 (Suppl 2):709-718. PubMed PMID: 33250618
Published date: 2020
Genetic Factors of Alzheimer's Disease Modulate How Diet is Associated with Long-Term Cognitive Trajectories: A UK Biobank Study.
Klinedinst BS, Le ST, Larsen B, Pappas C, Hoth NJ, Pollp eter A, Wang Q, Wang Y, Yu S, Wang L, Allenspach K, Mochel JP, Bennett DA, Willette AA
Journal of Alzheimer's disease : JAD 78 (3):1245-1257. PubMed PMID: 33252089
Published date: 2020
The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages.
Li S, Weinstein G, Zare H, Teumer A, Vlker U, Friedrich N, Knol MJ, Satizabal CL, Petyuk VA, Adams HHH, Launer LJ, Bennett DA, De Jager PL, Grabe HJ, Ikram MA, Gudnason V, Yang Q, Seshadri S
Brain communications 2 (2):fcaa176. PubMed PMID: 33345186
Published date: 2020
Is Healthy Neuroticism Associated with Longevity? A Coordinated Integrative Data Analysis.
Turiano NA, Graham EK, Weston SJ, Booth T, Harrison F, James BD, Lewis NA, Makkar SR, Mueller S, Wisniewski KM, Zhaoyang R, Spiro A, Willis S, Schaie KW, Lipton RB, Katz M, Sliwinski M, Deary IJ, Zelinski EM, Bennett DA, Sachdev PS, Brodaty H, Trollor JN,
Collabra. Psychology. PubMed PMID: 33354648
Published date: 2020
Is Healthy Neuroticism Associated with Health Behaviors? A Coordinated Integrative Data Analysis.
Graham EK, Weston SJ, Turiano NA, Aschwanden D, Booth T, Harrison F, James BD, Lewis NA, Makkar SR, Mueller S, Wisniewski KM, Yoneda T, Zhaoyang R, Spiro A, Willis S, Schaie KW, Sliwinski M, Lipton RA, Katz MJ, Deary IJ, Zelinski EM, Bennett DA, Sachdev P
Collabra. Psychology. PubMed PMID: 33354649
Published date: 2020
Representation of Older Latinxs in Cohort Studies at the Rush Alzheimer's Disease Center.
Marquez DX, Glover CM, Lamar M, Leurgans SE, Shah RC, Barnes LL, Aggarwal NT, Buchman AS, Bennett DA
Neuroepidemiology 54 (5):404-418. PubMed PMID: 32906123
Published date: 2020
Proportion of cognitive loss attributable to terminal decline.
Wilson RS, Yu L, Leurgans SE, Bennett DA, Boyle PA
Neurology 94 (1):e42-e50. PubMed PMID: 31792096
Published date: 2019 Dec 02
Braak neurofibrillary tangle staging prediction from invivo MRI metrics.
Dallaire-Throux C, Beheshti I, Potvin O, Dieumegarde L, Saikali S, Duchesne S
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 31517022
Published date: 2019 Dec
Hospitalization, Alzheimer's Disease and Related Neuropathologies, and Cognitive Decline.
James BD, Wilson RS, Capuano AW, Boyle PA, Shah RC, Lamar M, Ely EW, Bennett DA, Schneider JA
Annals of neurology 86 (6):844-852. PubMed PMID: 31614018
Published date: 2019 12
Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology.
Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Chen Y, Chen K, Chao MV, Counts SE, Mufson EJ
Neurobiology of disease. PubMed PMID: 31349032
Published date: 2019 12
Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers.
Wise EA, Rosenberg PB, Lyketsos CG, Leoutsakos JM
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 31024987
Published date: 2019 Dec
Transformation model estimation of survival under dependent truncation and independent censoring.
Chiou SH, Austin MD, Qian J, Betensky RA
Statistical methods in medical research 28 (12):3785-3798. PubMed PMID: 30543153
Published date: 2019 12
Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis.
Huo Z, Yu L, Yang J, Zhu Y, Bennett DA, Zhao J
Neurobiology of aging. PubMed PMID: 31785839
Published date: 2019 Nov 05
What Is Dementia?
Arvanitakis Z, Bennett DA
JAMA 322 (17):1728. PubMed PMID: 31688886
Published date: 2019 11 05
Cognitive and functional progression of dementia in two longitudinal studies.
Wang Y, Haaksma ML, Ramakers IHGB, Verhey FRJ, van de Flier WM, Scheltens P, van Maurik I, Olde Rikkert MGM, Leoutsakos JS, Melis RJF
International journal of geriatric psychiatry 34 (11):1623-1632. PubMed PMID: 31318090
Published date: 2019 Nov
Associations of autozygosity with a broad range of human phenotypes.
Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, Zhang W, Medina-Gomez C, Karlsson R, Bao Y, Bartz TM, Baumbach C, Biino G, Bixley MJ, Brumat M, Chai J
Nature communications 10 (1):4957. PubMed PMID: 31673082
Published date: 2019 Oct 31
Diagnosis and Management of Dementia: Review.
Arvanitakis Z, Shah RC, Bennett DA
JAMA 322 (16):1589-1599. PubMed PMID: 31638686
Published date: 2019 Oct 22
Genetic architecture of subcortical brain structures in 38,851 individuals.
Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desri
Nature genetics 51 (11):1624-1636. PubMed PMID: 31636452
Published date: 2019 Oct 21
Association Between High School Personality Phenotype and Dementia 54 Years Later in Results From a National US Sample.
Chapman BP, Huang A, Peters K, Horner E, Manly J, Bennett DA, Lapham S
JAMA psychiatry 77 (2):148-154. PubMed PMID: 31617877
Published date: 2019 Oct 16
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM
Cell reports 29 (2):301-316.e10. PubMed PMID: 31597093
Published date: 2019 Oct 08
3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.
Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH
Communications biology 2 (1):360. PubMed PMID: 31925184
Published date: 2019 Oct 04
Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults.
Tasaki S, Gaiteri C, Petyuk VA, Blizinsky KD, De Jager PL, Buchman AS, Bennett DA
Translational psychiatry 9 (1):241. PubMed PMID: 31582723
Published date: 2019 Oct 03
Regulation of lifespan by neural excitation and REST.
Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaicovo MP, Yankner BA
Nature 574 (7778):359-364. PubMed PMID: 31619788
Published date: 2019 Oct
Common age-related neuropathologies and yearly variability in cognition.
Yu L, Wang T, Wilson RS, Leurgans S, Schneider JA, Bennett DA, Boyle PA
Annals of clinical and translational neurology 6 (11):2140-2149. PubMed PMID: 31568713
Published date: 2019 Sep 30
The Health and Retirement Study Harmonized Cognitive Assessment Protocol Project: Study Design and Methods.
Langa KM, Ryan LH, McCammon RJ, Jones RN, Manly JJ, Levine DA, Sonnega A, Farron M, Weir DR
Neuroepidemiology 54 (1):1-11. PubMed PMID: 31563909
Published date: 2019 Sep 27
Sex differences in mixed neuropathologies in community-dwelling older adults.
Barnes LL, Lamar M, Schneider JA
Brain research. PubMed PMID: 31128096
Published date: 2019 Sep 15
Accelerometer Physical Activity is Associated with Greater Gray Matter Volumes in Older Adults Without Dementia or Mild Cognitive Impairment.
Halloway S, Arfanakis K, Wilbur J, Schoeny ME, Pressler SJ
The journals of gerontology. Series B, Psychological sciences and social sciences 74 (7):1142-1151. PubMed PMID: 29432610
Published date: 2019 Sep 15
Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.
Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, Bennett DA, Gearing M, Juncos JL, Kramer J, Lee SE, Yokoyama JS, Mendez MF, Chui
Alzheimer disease and associated disorders 33 (4):327-330. PubMed PMID: 31513029
Published date: 2019 Sep 10
Sex differences in the genetic predictors of Alzheimer's pathology.
Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Deming Y, Chao MJ, Huentelman M, Martin ER, Hamilton-Nelson K, S
Brain : a journal of neurology 142 (9):2581-2589. PubMed PMID: 31497858
Published date: 2019 Sep 01
The Multilingual Naming Test (MINT) as a Measure of Picture Naming Ability in Alzheimer's Disease.
Stasenko A, Jacobs DM, Salmon DP, Gollan TH
Journal of the International Neuropsychological Society : JINS 25 (8):821-833. PubMed PMID: 31248465
Published date: 2019 Sep
Reply: LATE to the PART-y.
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Fardo DW, Flanagan ME, Halliday G, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovacs GG, Kukull WA, Levey
Brain : a journal of neurology 142 (9):e48. PubMed PMID: 31359039
Published date: 2019 Sep 01
Factors influencing attrition in 35 Alzheimer's Disease Centers across the USA: a longitudinal examination of the National Alzheimer's Coordinating Center's Uniform Data Set.
Burke SL, Hu T, Naseh M, Fava NM, O'Driscoll J, Alvarez D, Cottler LB, Duara R
Aging clinical and experimental research 31 (9):1283-1297. PubMed PMID: 30535620
Published date: 2019 Sep
Trajectories of neuropsychiatric symptoms over time in healthy volunteers and risk of MCI and dementia.
Leoutsakos JS, Wise EA, Lyketsos CG, Smith GS
International journal of geriatric psychiatry 34 (12):1865-1873. PubMed PMID: 31452260
Published date: 2019 Aug 26
Cognitive function and neuropathological outcomes: a forward-looking approach.
Munoz E, Filshtein T, Bettcher BM, McLaren D, Hedden T, Tommet D, Mungas D, Therneau T
Journal of neurology 266 (12):2920-2928. PubMed PMID: 31435771
Published date: 2019 Aug 21
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain.
Ng B, Casazza W, Patrick E, Tasaki S, Novakovsky G, Felsky D, Ma Y, Bennett DA, Gaiteri C, De Jager PL, Mostafavi S
American journal of human genetics 105 (3):562-572. PubMed PMID: 31447098
Published date: 2019 Aug 21
Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
Wang HY, Capuano AW, Khan A, Pei Z, Lee KC, Bennett DA, Ahima RS, Arnold SE, Arvanitakis Z
Neurobiology of aging. PubMed PMID: 31539648
Published date: 2019 Aug 20
Cognitive heterogeneity in probable Alzheimer disease: Clinical and neuropathologic features.
Qiu Y, Jacobs DM, Messer K, Salmon DP, Feldman HH
Neurology 93 (8):e778-e790. PubMed PMID: 31320469
Published date: 2019 Aug 20
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE 4 on Alzheimer's Disease Risk in a Multiracial Sample.
Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, Chong A, Byun MS, Seo S, Ko PW, Han JW, McLean C, Farrell J, Lunetta KL, Miyashita A, Hara N, Won S, Choi SM, Ha JM, Jeong J
Journal of clinical medicine. PubMed PMID: 31426376
Published date: 2019 Aug 16
cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM
Cell reports 28 (7):1799-1813.e5. PubMed PMID: 31412248
Published date: 2019 Aug 13
Depression, subjective cognitive decline, and the risk of neurocognitive disorders.
Liew TM
Alzheimer's research & therapy 11 (1):70. PubMed PMID: 31399132
Published date: 2019 Aug 09
Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics.
Gaiteri C, Dawe R, Mostafavi S, Blizinsky KD, Tasaki S, Komashko V, Yu L, Wang Y, Schneider JA, Arfanakis K, De Jager PL, Bennett DA
Brain imaging and behavior 13 (4):963-972. PubMed PMID: 29934819
Published date: 2019 Aug
The Association Between the Number of Neuropsychological Measures and the Base Rate of Low Scores.
Oltra-Cucarella J, Snchez-SanSegundo M, Rubio-Aparicio M, Arango-Lasprilla JC, Ferrer-Cascales R
Assessment 28 (3):1073191119864646. PubMed PMID: 31364385
Published date: 2019 Jul 31
Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline.
Kim N, Yu L, Dawe R, Petyuk VA, Gaiteri C, De Jager PL, Schneider JA, Arfanakis K, Bennett DA
Neurobiology of aging. PubMed PMID: 31479860
Published date: 2019 Jul 26
Group differences in normal neuropsychological test performance for older non-Hispanic White and Black/African American adults.
Werry AE, Daniel M, Bergstrm B
Neuropsychology 33 (8):1089-1100. PubMed PMID: 31343234
Published date: 2019 Jul 25
Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease.
Canchi S, Raao B, Masliah D, Rosenthal SB, Sasik R, Fisch KM, De Jager PL, Bennett DA, Rissman RA
Cell reports 28 (4):1103-1116.e4. PubMed PMID: 31340147
Published date: 2019 Jul 23
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
Mahoney ER, Dumitrescu L, Moore AM, Cambronero FE, De Jager PL, Koran MEI, Petyuk VA, Robinson RAS, Goyal S, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ
Molecular psychiatry 26 (3):888-896. PubMed PMID: 31332262
Published date: 2019 Jul 22
Attitudes toward advance care planning among persons with dementia and their caregivers.
Pettigrew C, Brichko R, Black B, O'Connor MK, Austrom MG, Robinson MT, Lindauer A, Shah RC, Peavy GM, Meyer K, Schmitt FA, Lingler JH, Domoto-Reilly K, Farrar-Edwards D, Albert M
International psychogeriatrics 5 (5):1-15. PubMed PMID: 31309906
Published date: 2019 Jul 16
Identifying and ranking potential driver genes of Alzheimer's disease using multiview evidence aggregation.
Mukherjee S, Perumal TM, Daily K, Sieberts SK, Omberg L, Preuss C, Carter GW, Mangravite LM, Logsdon BA
Bioinformatics (Oxford, England) 35 (14):i568-i576. PubMed PMID: 31510680
Published date: 2019 07 15
The impact of cardiovascular risk factors on cognition in Hispanics and non-Hispanic whites.
Stickel A, McKinnon A, Ruiz J, Grilli MD, Ryan L
Learning & memory (Cold Spring Harbor, N.Y.) 26 (7):235-244. PubMed PMID: 31209118
Published date: 2019 Jul
Discriminative Ability of Montreal Cognitive Assessment Subtests and Items in Racial and Ethnic Minority Groups.
Milani SA, Marsiske M, Striley CW
Alzheimer disease and associated disorders 33 (3):226-232. PubMed PMID: 31058685
Published date: 2019 Jul-Sep
Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer's neuropathology.
Teylan M, Besser LM, Crary JF, Mock C, Gauthreaux K, Thomas NM, Chen YC, Kukull WA
Laboratory investigation; a journal of technical methods and pathology 99 (7):1049-1055. PubMed PMID: 30710118
Published date: 2019 Jul
Associations Between Depression, Traumatic Brain Injury, and Cognitively-Defined Late-Onset Alzheimer's Disease Subgroups.
Bauman J, Gibbons LE, Moore M, Mukherjee S, McCurry SM, McCormick W, Bowen JD, Trittschuh E, Glymour M, Mez J, Saykin AJ, Dams-O'Conner K, Bennett DA, Larson EB, Crane PK
Journal of Alzheimer's disease : JAD 70 (2):609-617. PubMed PMID: 31256124
Published date: 2019 Jun 24
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
Nagpal S, Meng X, Epstein MP, Tsoi LC, Patrick M, Gibson G, De Jager PL, Bennett DA, Wingo AP, Wingo TS, Yang J
American journal of human genetics 105 (2):258-266. PubMed PMID: 31230719
Published date: 2019 Jun 10
Motoric cognitive risk syndrome and predictors of transition to dementia: A multicenter study.
Verghese J, Wang C, Bennett DA, Lipton RB, Katz MJ, Ayers E
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (7):870-877. PubMed PMID: 31164315
Published date: 2019 Jun 01
Rate of brain aging and APOE 4 are synergistic risk factors for Alzheimer's disease.
Glorioso CA, Pfenning AR, Lee SS, Bennett DA, Sibille EL, Kellis M, Guarente LP
Life science alliance 2 (3):2218-9. PubMed PMID: 31133613
Published date: 2019 Jun
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report.
Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, Hokkanen SRK, Hunter S, Jicha GA, Katsumata Y, Kawas CH, Keene CD, Kovac
Brain : a journal of neurology 142 (6):1503-1527. PubMed PMID: 31039256
Published date: 2019 Jun 01
Risk of dementia and mild cognitive impairment among older adults in same-sex relationships.
Perales-Puchalt J, Gauthreaux K, Flatt J, Teylan MA, Resendez J, Kukull WA, Chan KCG, Burns J, Vidoni ED
International journal of geriatric psychiatry 34 (6):828-835. PubMed PMID: 30864178
Published date: 2019 06
Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms.
Keine D, Zelek M, Walker JQ, Sabbagh MN
Neurology and therapy 8 (1):79-94. PubMed PMID: 30900186
Published date: 2019 Jun
Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease.
Bihlmeyer NA, Merrill E, Lambert Y, Srivastava GP, Clark TW, Hyman BT, Das S
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (6):788-798. PubMed PMID: 30935898
Published date: 2019 Jun
HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease.
Mahady L, Nadeem M, Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ
Neuropathology and applied neurobiology 45 (4):380-397. PubMed PMID: 30252960
Published date: 2019 Jun
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, Lunetta KL
Aging cell 18 (4):e12964. PubMed PMID: 31144443
Published date: 2019 May 29
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms.
Li P, Marshall L, Oh G, Jakubowski JL, Groot D, He Y, Wang T, Petronis A, Labrie V
Nature communications 10 (1):2246. PubMed PMID: 31113950
Published date: 2019 05 21
Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
Tobin MK, Musaraca K, Disouky A, Shetti A, Bheri A, Honer WG, Kim N, Dawe RJ, Bennett DA, Arfanakis K, Lazarov O
Cell stem cell 24 (6):974-982.e3. PubMed PMID: 31130513
Published date: 2019 May 16
Genome-wide association studies of alcohol dependence, DSM-IV criterion count, and individual criteria.
Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hari
Genes, brain, and behavior 18 (6):e12579. PubMed PMID: 31090166
Published date: 2019 May 14
Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology.
Arvanitakis Z, Capuano AW, Brey R, Fleischman DA, Arfanakis K, Buchman AS, Schneider JA, Levine SR, Bennett DA
Neuroepidemiology 53 (1-2):1-8. PubMed PMID: 31067547
Published date: 2019 May 08
Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease.
Tosto G, Vardarajan B, Sariya S, Brickman AM, Andrews H, Manly JJ, Schupf N, Reyes-Dumeyer D, Lantigua R, Bennett DA, De Jager PL, Mayeux R
JAMA neurology 89 (8):244-8. PubMed PMID: 31058951
Published date: 2019 May 06
Single-cell transcriptomic analysis of Alzheimer's disease.
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH
Nature 570 (7761):332-337. PubMed PMID: 31042697
Published date: 2019 May 01
Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease.
Vglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, Karch CM, Cairns N, Mori H, Schofield PR, Masters CL, Goate A, Buckles V, Fox N,
Brain : a journal of neurology 142 (5):1429-1440. PubMed PMID: 30897203
Published date: 2019 May 01
Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia.
Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Al osco ML
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (5):686-698. PubMed PMID: 30852157
Published date: 2019 05
Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.
Yu L, Petyuk VA, Tasaki S, Boyle PA, Gaiteri C, Schneider JA, De Jager PL, Bennett DA
JAMA neurology 34 (4):493-511. PubMed PMID: 31009033
Published date: 2019 Apr 22
Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.
Buchman AS, Yu L, Wilson RS, Leurgans SE, Nag S, Shulman JM, Barnes LL, Schneider JA, Bennett DA
Neurology 92 (16):e1821-e1830. PubMed PMID: 30894446
Published date: 2019 04 16
Confidence Intervals for the Area Under the Receiver Operating Characteristic Curve in the Presence of Ignorable Missing Data.
Cho H, Matthews GJ, Harel O
International statistical review = Revue internationale de statistique 87 (1):152-177. PubMed PMID: 31007356
Published date: 2019 Apr
Cholinesterase Inhibitors May Not Benefit Mild Cognitive Impairment and Mild Alzheimer Disease Dementia.
Han JY, Besser LM, Xiong C, Kukull WA, Morris JC
Alzheimer disease and associated disorders 33 (2):87-94. PubMed PMID: 30633043
Published date: 2019 Apr-Jun
DNA methylation variability in Alzheimer's disease.
Huo Z, Zhu Y, Yu L, Yang J, De Jager P, Bennett DA, Zhao J
Neurobiology of aging. PubMed PMID: 30660039
Published date: 2019 Apr
White matter correlates of scam susceptibility in community-dwelling older adults.
Lamar M, Arfanakis K, Yu L, Zhang S, Han SD, Fleischman DA, Bennett DA, Boyle PA
Brain imaging and behavior 60 (8):1143-8. PubMed PMID: 30895444
Published date: 2019 Mar 20
Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons.
Capuano AW, Wilson RS, Honer WG, Petyuk VA, Leurgans SE, Yu L, Gatchel JR, Arnold S, Bennett DA, Arvanitakis Z
Journal of affective disorders 250 (12):313-318. PubMed PMID: 30875674
Published date: 2019 Mar 08
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A, tau, immunity and lipid processing.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, R
Nature genetics 51 (3):414-430. PubMed PMID: 30820047
Published date: 2019 03
Prioritizing Parkinson's disease genes using population-scale transcriptomic data.
Li YI, Wong G, Humphrey J, Raj T
Nature communications 10 (1):994. PubMed PMID: 30824768
Published date: 2019 03 01
Integrative approach to sporadic Alzheimer's disease:deficiency of TYROBPin cerebral A amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing A
Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME
Molecular psychiatry 24 (3):431-446. PubMed PMID: 30283032
Published date: 2019 03
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.
Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (3):441-452. PubMed PMID: 30503768
Published date: 2019 Mar
Biomarkers for Alzheimer Dementia in Diverse Racial and Ethnic Minorities-A Public Health Priority.
Barnes LL
JAMA neurology 76 (3):251-253. PubMed PMID: 30615027
Published date: 2019 03 01
Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities.
Burke SL, Hu T, Fava NM, Li T, Rodriguez MJ, Schuldiner KL, Burgess A, Laird A
Journal of women & aging 31 (2):140-164. PubMed PMID: 29319430
Published date: 2019 Mar-Apr
Sedentary Time and White Matter Hyperintensity Volume in Older Adults.
Bronas UG, Steffen A, Dion C, Boots EA, Arfanakis K, Marquez DX, Lamar M
Medicine and science in sports and exercise 51 (8):1613-1618. PubMed PMID: 30817720
Published date: 2019 Feb 20
Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer's disease.
Bourassa P, Tremblay C, Schneider JA, Bennett DA, Calon F
Acta neuropathologica 137 (5):801-823. PubMed PMID: 30729296
Published date: 2019 Feb 07
Education and cognitive reserve in old age.
Wilson RS, Yu L, Lamar M, Schneider JA, Boyle PA, Bennett DA
Neurology 92 (10):e1041-e1050. PubMed PMID: 30728309
Published date: 2019 Feb 06
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
Karlsson Linnr R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Znd CL, Bao Y, Buzdugan L, Caplin AH, Chen CY, Eibich P, Fonta
Nature genetics 51 (2):245-257. PubMed PMID: 30643258
Published date: 2019 02
Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.
Katsumata Y, Nelson PT, Estus S, Fardo DW
Neurobiology of aging 74 (5):135-146. PubMed PMID: 30448613
Published date: 2019 02
APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults.
Lamar M, Yu L, Rubin LH, James BD, Barnes LL, Farfel JM, Gaiteri C, Buchman AS, Bennett DA, Schneider JA
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (2):258-266. PubMed PMID: 30321502
Published date: 2019 02
Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.
Makkinejad N, Schneider JA, Yu J, Leurgans SE, Kotrotsou A, Evia AM, Bennett DA, Arfanakis K
Neurobiology of aging 77 (11):104-111. PubMed PMID: 30784812
Published date: 2019 Jan 31
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
Felsky D, Roostaei T, Nho K, Risacher SL, Bradshaw EM, Petyuk V, Schneider JA, Saykin A, Bennett DA, De Jager PL
Nature communications 10 (1):409. PubMed PMID: 30679421
Published date: 2019 Jan 24
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, Kukull WA, Tosun D, Weiner MW, Sperling RA, Bennett DA, Hyman BT, Andreassen OA, Dale AM,
Brain : a journal of neurology 142 (2):460-470. PubMed PMID: 30689776
Published date: 2019 Jan 24
Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
Wilson RS, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Bennett DA, Boyle PA
Neurology 92 (8):e831-e840. PubMed PMID: 30674595
Published date: 2019 Jan 23
Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain.
Dintica CS, Marseglia A, Rizzuto D, Wang R, Seubert J, Arfanakis K, Bennett DA, Xu W
Neurology 92 (7):e700-e709. PubMed PMID: 30651382
Published date: 2019 Jan 16
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartans
Neurology 92 (5):e486-503. PubMed PMID: 30651383
Published date: 2019 Jan 16
Causes and Patterns of Dementia: An Update in the Era of Redefining Alzheimer's Disease.
James BD, Bennett DA
Annual review of public health. PubMed PMID: 30642228
Published date: 2019 Jan 14
Cognitive decline after elective and nonelective hospitalizations in older adults.
James BD, Wilson RS, Capuano AW, Boyle PA, Shah RC, Lamar M, Ely EW, Bennett DA, Schneider JA
Neurology 92 (7):e690-e699. PubMed PMID: 30635482
Published date: 2019 Jan 11
Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study.
Oh G, Abner EL, Fardo DW, Freeman PR, Moga DC
PloS one 14 (1):e0210341. PubMed PMID: 30633773
Published date: 2019
Parental Perception of the Factors that Affect Diabetes Management in Youth.
Davis V, Telang SB, Jain S, Davis Ramos MV, Ward MA, Jindal I, Aschkenasy JR, Glover CM, Shah RC
Clinical diabetes : a publication of the American Diabetes Association 37 (1):50-56. PubMed PMID: 30705497
Published date: 2019 Jan
Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants.
Bardach SH, Jicha GA, Karanth S, Zhang X, Abner EL
Journal of Alzheimer's disease : JAD 69 (1):123-133. PubMed PMID: 30958359
Published date: 2019
Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment.
Curcio N, Wilmoth K, LoBue C, Cullum CM
Journal of central nervous system disease. PubMed PMID: 31040738
Published date: 2019
Cognition may link cortical IGFBP5 levels with motor function in older adults.
Buchman AS, Yu L, Petyuk VA, Gaiteri C, Tasaki S, Blizinsky KD, Schneider JA, De Jager PL, Bennett DA
PloS one 14 (8):e0220968. PubMed PMID: 31404102
Published date: 2019
Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials.
Andrews JS, Desai U, Kirson NY, Zichlin ML, Ball DE, Matthews BR
Alzheimer's & dementia (New York, N. Y.). PubMed PMID: 31417957
Published date: 2019
Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease.
Mufson EJ, Counts SE, Ginsberg SD, Mahady L, Perez SE, Massa SM, Longo FM, Ikonomovic MD
Frontiers in neuroscience. PubMed PMID: 31312116
Published date: 2019
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupki
Communications biology. PubMed PMID: 31396565
Published date: 2019
Expanding instrumented gait testing in the community setting: A portable, depth-sensing camera captures joint motion in older adults.
Dawe RJ, Yu L, Leurgans SE, Truty T, Curran T, Hausdorff JM, Wimmer MA, Block JA, Bennett DA, Buchman AS
PloS one 14 (5):e0215995. PubMed PMID: 31091267
Published date: 2019
Associations between Comorbid TDP-43, Lewy Body Pathology, and Neuropsychiatric Symptoms in Alzheimer's Disease.
Bayram E, Shan G, Cummings JL
Journal of Alzheimer's disease : JAD 69 (4):953-961. PubMed PMID: 31127776
Published date: 2019
Neurofibrillary Tangles and Conversion to Mild Cognitive Impairment with Certain Antihypertensives.
Wharton W, Zhao L, Steenland K, Goldstein FC, Schneider JA, Barnes LL, Gearing M, Yasar S
Journal of Alzheimer's disease : JAD 70 (1):153-161. PubMed PMID: 31177216
Published date: 2019
Exploring the Correlation between the Cognitive Benefits of Drug Combinations in a Clinical Database and the Efficacies of the Same Drug Combinations Predicted from a Computational Model.
Anastasio TJ
Journal of Alzheimer's disease : JAD 70 (1):287-302. PubMed PMID: 31177222
Published date: 2019
The Pathology of Rapid Cognitive Decline in Clinically Diagnosed Alzheimer's Disease.
Nance C, Ritter A, Miller JB, Lapin B, Banks SJ
Journal of Alzheimer's disease : JAD 70 (4):983-993. PubMed PMID: 31306127
Published date: 2019
Cerebral Amyloid Angiopathy and Neuritic Plaque Pathology Correlate with Cognitive Decline in Elderly Non-Demented Individuals.
Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ
Journal of Alzheimer's disease : JAD 67 (1):411-422. PubMed PMID: 30594928
Published date: 2019
Abnormal Sleep Behaviours Across the Spectrum of Alzheimer's Disease Severity: Influence of APOE Genotypes and Lewy Bodies.
Koo KYG, Schweizer TA, Fischer CE, Munoz DG
Current Alzheimer research 16 (3):243-250. PubMed PMID: 30605058
Published date: 2019
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL
Nature neuroscience 22 (1):37-46. PubMed PMID: 30559478
Published date: 2019 Jan
Inferring the Molecular Mechanisms of Noncoding Alzheimer's Disease-Associated Genetic Variants.
Amlie-Wolf A, Tang M, Way J, Dombroski B, Jiang M, Vrettos N, Chou YF, Zhao Y, Kuzma A, Mlynarski EE, Leung YY, Brown CD, Wang LS, Schellenberg GD
Journal of Alzheimer's disease : JAD 72 (1):301-318. PubMed PMID: 31561366
Published date: 2019
3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.
Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH
Communications biology. PubMed PMID: 31602409
Published date: 2019
Recruitment and retention of underrepresented populations in Alzheimer's disease research: A systematic review.
Gilmore-Bykovskyi AL, Jin Y, Gleason C, Flowers-Benton S, Block LM, Dilworth-Anderson P, Barnes LL, Shah MN, Zuelsdorff M
Alzheimer's & dementia (New York, N. Y.). PubMed PMID: 31921966
Published date: 2019
A Machine Learning Method for Identifying Critical Interactions Between Gene Pairs in Alzheimer's Disease Prediction.
Chen H, He Y, Ji J, Shi Y
Frontiers in neurology. PubMed PMID: 31736866
Published date: 2019
miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer's Patients.
Cha DJ, Mengel D, Mustapic M, Liu W, Selkoe DJ, Kapogiannis D, Galasko D, Rissman RA, Bennett DA, Walsh DM
Frontiers in neuroscience. PubMed PMID: 31849573
Published date: 2019
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Wang H, Li Y, Ryder JW, Hole JT, Ebert PJ, Airey DC, Qian HR, Logsdon B, Fisher A, Ahmed Z, Murray TK, Cavallini A, Bose S, Eastwood BJ, Collier DA, Dage JL, Miller BB, Merchant KM, O'Neill MJ, Demattos RB
Molecular neurodegeneration 13 (1):65. PubMed PMID: 30558641
Published date: 2018 12 17
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
Mukherjee S, Mez J, Trittschuh EH, Saykin AJ, Gibbons LE, Fardo DW, Wessels M, Bauman J, Moore M, Choi SE, Gross AL, Rich J, Louden DKN, Sanders RE, Grabowski TJ, Bird TD, McCurry SM, Snitz BE, Kamboh MI, Lopez OL, De Jager PL, Bennett DA, Keene CD, Larso
Molecular psychiatry 25 (11):2942-2951. PubMed PMID: 30514930
Published date: 2018 Dec 04
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V, Starks T, Byfield GE, Sierra Lopez CB, McCauley JL, Acosta H, Chinea A, Kunkle BW, Reitz C, Farrer LA, Schellenberg GD, Vardar
PLoS genetics 14 (12):e1007791. PubMed PMID: 30517106
Published date: 2018 12
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
Beecham GW, Vardarajan B, Blue E, Bush W, Jaworski J, Barral S, DeStefano A, Hamilton-Nelson K, Kunkle B, Martin ER, Naj A, Rajabli F, Reitz C, Thornton T, van Duijn C, Goate A, Seshadri S, Farrer LA, Boerwinkle E, Schellenberg G, Haines JL, Wijsman E, Ma
Neurology. Genetics 4 (6):e286. PubMed PMID: 30569016
Published date: 2018 Dec
Bias in parameter estimates due to omitting gene-environment interaction terms in case-control studies.
Lobach I
Genetic epidemiology 42 (8):838-845. PubMed PMID: 30302820
Published date: 2018 12
Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, Lunnon K
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (12):1580-1588. PubMed PMID: 29550519
Published date: 2018 Dec
Performance validity in older adults: Observed versus predicted false positive rates in relation to number of tests administered.
Davis JJ
Journal of clinical and experimental neuropsychology 40 (10):1013-1021. PubMed PMID: 29779432
Published date: 2018 12
Toward Prevention of Mild Cognitive Impairment in Older Adults With Depression: An Observational Study of Potentially Modifiable Risk Factors.
Gallagher D, Kiss A, Lanctot KL, Herrmann N
The Journal of clinical psychiatry 80 (1):354-363. PubMed PMID: 30549490
Published date: 2018 11 27
Quantitative Assessment of Pathological Tau Burden in Essential Tremor: A Postmortem Study.
Farrell K, Cosentino S, Iida MA, Chapman S, Bennett DA, Faust PL, Louis ED, Crary JF
Journal of neuropathology and experimental neurology 78 (1):31-37. PubMed PMID: 30476290
Published date: 2018 Nov 23
Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies.
Boyle PA, Yu L, Leurgans SE, Wilson RS, Brookmeyer R, Schneider JA, Bennett DA
Annals of neurology 85 (1):114-124. PubMed PMID: 30421454
Published date: 2018 Nov 12
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vanc
Acta neuropathologica 137 (2):209-226. PubMed PMID: 30413934
Published date: 2018 Nov 09
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
Sullivan SE, Liao M, Smith RV, White C, Lagomarsino VN, Xu J, Taga M, Bennett DA, De Jager PL, Young-Pearse TL
Human molecular genetics 28 (5):718-735. PubMed PMID: 30371777
Published date: 2018 Oct 26
In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.
Hanko V, Apple AC, Alpert KI, Warren KN, Schneider JA, Arfanakis K, Bennett DA, Wang L
Neurobiology of aging 74 (2):171-181. PubMed PMID: 30453234
Published date: 2018 Oct 25
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly.
McNeil JJ, Nelson MR, Woods RL, Lockery JE, Wolfe R, Reid CM, Kirpach B, Shah RC, Ives DG, Storey E, Ryan J, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA,
The New England journal of medicine 379 (16):1519-1528. PubMed PMID: 30221595
Published date: 2018 10 18
Effect of Aspirin on Disability-free Survival in the Healthy Elderly.
McNeil JJ, Woods RL, Nelson MR, Reid CM, Kirpach B, Wolfe R, Storey E, Shah RC, Lockery JE, Tonkin AM, Newman AB, Williamson JD, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Orchard SG, Trevaks RE, Beilin LJ, Donnan GA, Gibbs P, Johnsto
The New England journal of medicine 379 (16):1499-1508. PubMed PMID: 30221596
Published date: 2018 10 18
Sex differences in Alzheimer's disease and common neuropathologies of aging.
Oveisgharan S, Arvanitakis Z, Yu L, Farfel J, Schneider JA, Bennett DA
Acta neuropathologica 136 (6):887-900. PubMed PMID: 30334074
Published date: 2018 Oct 17
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, Louie G, Kueider-Paisley A, Moseley MA, Thompson JW, St John Williams L, Tenenbaum JD, Blach C, Baillie R, Han X, Bhattacharyya S, Toledo JB, Schafferer S, Klein S, Koal T, Risacher SL, Kling M
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (1):76-92. PubMed PMID: 30337151
Published date: 2018 Oct 08
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, Bennett DA, De Jager PL
Nature genetics 50 (11):1584-1592. PubMed PMID: 30297968
Published date: 2018 Oct 08
Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia?
Crum J, Wilson J, Sabbagh M
Alzheimer's research & therapy 10 (1):104. PubMed PMID: 30285877
Published date: 2018 10 02
Deconstructing and targeting the genomic architecture of human neurodegeneration.
De Jager PL, Yang HS, Bennett DA
Nature neuroscience 21 (10):1310-1317. PubMed PMID: 30258235
Published date: 2018 Oct
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology.
Rangasamy SB, Jana M, Roy A, Corbett GT, Kundu M, Chandra S, Mondal S, Dasarathi S, Mufson EJ, Mishra RK, Luan CH, Bennett DA, Pahan K
The Journal of clinical investigation 128 (10):4297-4312. PubMed PMID: 29990310
Published date: 2018 10 01
Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout.
Agogo GO, Ramsey CM, Gnjidic D, Moga DC, Allore H
International psychogeriatrics 30 (10):1477-1487. PubMed PMID: 29667565
Published date: 2018 10
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, B
Nature communications 9 (1):3945. PubMed PMID: 30258056
Published date: 2018 09 26
An MRI biomarker of mixed pathology.
Bennett DA
Neurology 91 (15):682-683. PubMed PMID: 30217934
Published date: 2018 Sep 14
Cognitive composite score association with Alzheimer's disease plaque and tangle pathology.
Malek-Ahmadi M, Chen K, Perez SE, He A, Mufson EJ
Alzheimer's research & therapy 10 (1):90. PubMed PMID: 30205840
Published date: 2018 09 11
The Impact of Dementia Diagnosis on Patterns of Potentially Inappropriate Medication Use Among Older Adults.
Gnjidic D, Agogo GO, Ramsey CM, Moga DC, Allore H
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (10):1410-1417. PubMed PMID: 29684111
Published date: 2018 09 11
Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects.
Ahmad F, Das D, Kommaddi RP, Diwakar L, Gowaikar R, Rupanagudi KV, Bennett DA, Ravindranath V
Scientific reports 8 (1):13119. PubMed PMID: 30177812
Published date: 2018 Sep 03
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
Lim ASP, Gaiteri C, Yu L, Sohail S, Swardfager W, Tasaki S, Schneider JA, Paquet C, Stuss DT, Masellis M, Black SE, Hugon J, Buchman AS, Barnes LL, Bennett DA, De Jager PL
PLoS medicine 15 (9):e1002647. PubMed PMID: 30180184
Published date: 2018 Sep
Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study.
Yang HS, Yu L, White CC, Chibnik LB, Chhatwal JP, Sperling RA, Bennett DA, Schneider JA, De Jager PL
The Lancet. Neurology 17 (9):773-781. PubMed PMID: 30093249
Published date: 2018 Sep
Understanding the impact of sex and gender in Alzheimer's disease: A call to action.
Nebel RA, Aggarwal NT, Barnes LL, Gallagher A, Goldstein JM, Kantarci K, Mallampalli MP, Mormino EC, Scott L, Yu WH, Maki PM, Mielke MM
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (9):1171-1183. PubMed PMID: 29907423
Published date: 2018 09
Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.
Tiernan CT, Ginsberg SD, He B, Ward SM, Guillozet-Bongaarts AL, Kanaan NM, Mufson EJ, Counts SE
Neurobiology of disease. PubMed PMID: 29859871
Published date: 2018 Sep
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, De Jager P, Schneider JA, Morris CM, McKeith IG, Perry RH, Lovestone S, Woltjer RL
Brain : a journal of neurology 141 (9):2721-2739. PubMed PMID: 30137212
Published date: 2018 Aug 20
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples
Molecular psychiatry 25 (8):1859-1875. PubMed PMID: 30108311
Published date: 2018 Aug 14
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.
Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, Ikram MA, Mayeux R, Farrer LA, Haines JL, Pericak-Vance MA, Schellenbe
Neurobiology of aging. PubMed PMID: 30201328
Published date: 2018 Aug 09
A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA
Scientific data. PubMed PMID: 30084846
Published date: 2018 Aug 07
Late-life blood pressure association with cerebrovascular and Alzheimer disease pathology.
Arvanitakis Z, Capuano AW, Lamar M, Shah RC, Barnes LL, Bennett DA, Schneider JA
Neurology 91 (6):e517-e525. PubMed PMID: 29997190
Published date: 2018 08 07
Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults.
Burke SL, Cadet T, Maddux M
Journal of the National Medical Association 110 (4):314-325. PubMed PMID: 30126555
Published date: 2018 Aug
Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes.
Haaksma ML, Caldern-Larraaga A, Olde Rikkert MGM, Melis RJF, Leoutsakos JS
International journal of geriatric psychiatry 33 (8):1057-1064. PubMed PMID: 29761569
Published date: 2018 08
Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
Bove RM, Patrick E, Aubin CM, Srivastava G, Schneider JA, Bennett DA, De Jager PL, Chibnik LB
PloS one 13 (7):e0199073. PubMed PMID: 30052629
Published date: 2018
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
Felsky D, Patrick E, Schneider JA, Mostafavi S, Gaiteri C, Patsopoulos N, Bennett DA, De Jager PL
Molecular neurodegeneration 13 (1):38. PubMed PMID: 30041668
Published date: 2018 Jul 24
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linnr R, Fontana MA, Kundu T, Lee C, Li H, Li R, Royer R, Timshel PN, Walters RK, Willoughby EA, Yengo L, Alver M, Bao Y, Clark DW, Day FR, Furlotte NA
Nature genetics 50 (8):1112-1121. PubMed PMID: 30038396
Published date: 2018 07 23
Integrative DNA copy number detection and genotyping from sequencing and array-based platforms.
Zhou Z, Wang W, Wang LS, Zhang NR
Bioinformatics (Oxford, England) 34 (14):2349-2355. PubMed PMID: 29992253
Published date: 2018 07 15
White matter correlates of temporal discounting in older adults.
Han SD, Arfanakis K, Fleischman DA, Yu L, Bennett DA, Boyle PA
Brain structure & function 223 (8):3653-3663. PubMed PMID: 29992469
Published date: 2018 Jul 10
Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation.
Cheng H, Xuan H, Green CD, Han Y, Sun N, Shen H, McDermott J, Bennett DA, Lan F, Han JJ
Proceedings of the National Academy of Sciences of the United States of America 115 (29):7611-7616. PubMed PMID: 29967166
Published date: 2018 Jul 02
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, John
Acta neuropathologica 136 (6):857-872. PubMed PMID: 29967939
Published date: 2018 Jul 02
Combined neuropathological pathways account for age-related risk of dementia.
Power MC, Mormino E, Soldan A, James BD, Yu L, Armstrong NM, Bangen KJ, Delano-Wood L, Lamar M, Lim YY, Nudelman K, Zahodne L, Gross AL, Mungas D, Widaman KF, Schneider J
Annals of neurology 84 (1):10-22. PubMed PMID: 29944741
Published date: 2018 07
Neopterin is associated with hippocampal subfield volumes and cognition in HIV.
Fleischman DA, Arfanakis K, Leurgans S, Keating SM, Lamar M, Bennett DA, Adeyemi OM, Barnes LL
Neurology(R) neuroimmunology & neuroinflammation 5 (4):e467. PubMed PMID: 29904644
Published date: 2018 Jul
Psychosis in "Cognitively Asymptomatic" Elderly Subjects is Associated With Neuritic Plaque Load, Not Neurofibrillary Tangles.
Kim J, Schweizer TA, Fischer CE, Munoz DG
Alzheimer disease and associated disorders 32 (3):185-189. PubMed PMID: 29553944
Published date: 2018 Jul-Sep
Analysis of shared heritability in common disorders of the brain.
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amou
Science (New York, N.Y.) 360 (6395):177-184. PubMed PMID: 29930110
Published date: 2018 06 22
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT
Neuron 99 (1):64-82.e7. PubMed PMID: 29937276
Published date: 2018 Jun 21
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Yu L, Petyuk VA, Gaiteri C, Mostafavi S, Young-Pearse T, Shah RC, Buchman AS, Schneider JA, Piehowski PD, Sontag RL, Fillmore TL, Shi T, Smith RD, De Jager PL, Bennett DA
Annals of neurology 84 (1):78-88. PubMed PMID: 29908079
Published date: 2018 Jun 16
Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks.
Wang T, Qiu RG, Yu M
Scientific reports 8 (1):9161. PubMed PMID: 29907747
Published date: 2018 06 15
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D, Akbarian S, Roussos P, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK
American journal of human genetics 102 (6):1169-1184. PubMed PMID: 29805045
Published date: 2018 06 07
Tau Activates Transposable Elements in Alzheimer's Disease.
Guo C, Jeong HH, Hsieh YC, Klein HU, Bennett DA, De Jager PL, Liu Z, Shulman JM
Cell reports 23 (10):2874-2880. PubMed PMID: 29874575
Published date: 2018 Jun 05
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL
Nature neuroscience 21 (6):811-819. PubMed PMID: 29802388
Published date: 2018 Jun
Watershed microinfarct pathology and cognition in older persons.
Kapasi A, Leurgans SE, James BD, Boyle PA, Arvanitakis Z, Nag S, Bennett DA, Buchman AS, Schneider JA
Neurobiology of aging. PubMed PMID: 29935416
Published date: 2018 May 30
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoum
Nature communications 9 (1):2098. PubMed PMID: 29844566
Published date: 2018 May 29
Religious Orders Study and Rush Memory and Aging Project.
Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA
Journal of Alzheimer's disease : JAD 64 (s1):S161-S189. PubMed PMID: 29865057
Published date: 2018 May 26
Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults.
Dawe RJ, Yu L, Schneider JA, Arfanakis K, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29908416
Published date: 2018 May 23
APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.
Oveisgharan S, Buchman AS, Yu L, Farfel J, Hachinski V, Gaiteri C, De Jager PL, Schneider JA, Bennett DA
Neurology 90 (24):e2127-e2134. PubMed PMID: 29752306
Published date: 2018 May 11
Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnso
JAMA neurology 75 (8):989-998. PubMed PMID: 29801024
Published date: 2018 May 07
TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.
Nag S, Yu L, Boyle PA, Leurgans SE, Bennett DA, Schneider JA
Acta neuropathologica communications 6 (1):33. PubMed PMID: 29716643
Published date: 2018 May 01
Positional effects revealed in Illumina methylation array and the impact on analysis.
Jiao C, Zhang C, Dai R, Xia Y, Wang K, Giase G, Chen C, Liu C
Epigenomics 10 (5):643-659. PubMed PMID: 29469594
Published date: 2018 05
DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia.
Tse KH, Cheng A, Ma F, Herrup K
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (5):664-679. PubMed PMID: 29328926
Published date: 2018 05
Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer's disease.
Schaffert J, LoBue C, White CL, Chiang HS, Didehbani N, Lacritz L, Rossetti H, Dieppa M, Hart J, Cullum CM
Neuropsychology 32 (4):410-416. PubMed PMID: 29389151
Published date: 2018 05
An epigenetic biomarker of aging for lifespan and healthspan.
Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S
Aging 10 (4):573-591. PubMed PMID: 29676998
Published date: 2018 04 18
Sexual dimorphism in predisposition to Alzheimer's disease.
Fisher DW, Bennett DA, Dong H
Neurobiology of aging. PubMed PMID: 29754747
Published date: 2018 Apr 17
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (4):535-562. PubMed PMID: 29653606
Published date: 2018 Apr
Testing Tele-Savvy: Protocol for a randomized controlled trial.
Kovaleva MA, Bilsborough E, Griffiths PC, Nocera J, Higgins M, Epps F, Kilgore K, Lindauer A, Morhardt D, Shah RC, Hepburn K
Research in nursing & health 41 (2):107-120. PubMed PMID: 29399825
Published date: 2018 Apr
Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis.
Nascimento C, Di Lorenzo Alho AT, Bazan Conceio Amaral C, Leite REP, Nitrini R, Jacob-Filho W, Pasqualucci CA, Hokkanen SRK, Hunter S, Keage H, Kovacs GG, Grinberg LT, Suemoto CK
Neuropathology and applied neurobiology 44 (3):286-297. PubMed PMID: 28793370
Published date: 2018 04
Consistency of traumatic brain injury reporting in older adults with and without cognitive impairment.
Wilmoth K, LoBue C, Clem MA, Reddy R, Hynan LS, Didehbani N, Bell K, Womack KB, Hart J, Batjer H, Cullum CM
The Clinical neuropsychologist 32 (3):524-529. PubMed PMID: 28988512
Published date: 2018 04
Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.
Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM
Genome medicine 10 (1):26. PubMed PMID: 29598827
Published date: 2018 Mar 29
Neurodegenerative disease and cognitive retest learning.
Wilson RS, Capuano AW, Yu L, Yang J, Kim N, Leurgans SE, Lamar M, Schneider JA, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29558667
Published date: 2018 Mar 17
Time-to-event data with time-varying biomarkers measured only at study entry, with applications to Alzheimer's disease.
Lee C, Betensky RA
Statistics in medicine 37 (6):914-932. PubMed PMID: 29266591
Published date: 2018 Mar 15
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Wang X, Philip VM, Ananda G, White CC, Malhotra A, Michalski PJ, Karuturi KRM, Chintalapudi SR, Acklin C, Sasner M, Bennett DA, De Jager PL, Howell GR, Carter GW
Genetics 209 (1):51-64. PubMed PMID: 29507048
Published date: 2018 Mar 05
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.
Montagne A, Nikolakopoulou AM, Zhao Z, Sagare AP, Si G, Lazic D, Barnes SR, Daianu M, Ramanathan A, Go A, Lawson EJ, Wang Y, Mack WJ, Thompson PM, Schneider JA, Varkey J, Langen R, Mullins E, Jacobs RE, Zlokovic BV
Nature medicine 24 (3):326-337. PubMed PMID: 29400711
Published date: 2018 03
Do subjects with minimal motor features have prodromal Parkinson disease?
Chu Y, Buchman AS, Olanow CW, Kordower JH
Annals of neurology 83 (3):562-574. PubMed PMID: 29420861
Published date: 2018 Mar
Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease.
Tiernan CT, Mufson EJ, Kanaan NM, Counts SE
Journal of neuropathology and experimental neurology 77 (3):246-259. PubMed PMID: 29378005
Published date: 2018 03 01
A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans.
McAninch EA, Rajan KB, Evans DA, Jo S, Chaker L, Peeters RP, Bennett DA, Mash DC, Bianco AC
The Journal of clinical endocrinology and metabolism 103 (5):1818-1826. PubMed PMID: 29481662
Published date: 2018 Feb 22
Memory complaints, dementia, and neuropathology in older blacks and whites.
Arvanitakis Z, Leurgans SE, Fleischman DA, Schneider JA, Rajan KB, Pruzin JJ, Shah RC, Evans DA, Barnes LL, Bennett DA
Annals of neurology 83 (4):718-729. PubMed PMID: 29466839
Published date: 2018 Feb 21
Alzheimer disease biomarkers and synucleinopathy.
Bennett DA, Gordon BA
Neurology 90 (12):537-538. PubMed PMID: 29467302
Published date: 2018 Feb 21
Longitudinal Modeling of Functional Decline Associated with Pathologic Alzheimer's Disease in Older Persons without Cognitive Impairment.
Wang D, Schultz T, Novak GP, Baker S, Bennett DA, Narayan VA
Journal of Alzheimer's disease : JAD 62 (2):855-865. PubMed PMID: 29480187
Published date: 2018
Static and Dynamic Cognitive Reserve Proxy Measures: Interactions with Alzheimer's Disease Neuropathology and Cognition.
Malek-Ahmadi M, Lu S, Chan Y, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease & Parkinsonism 7 (6):40-50. PubMed PMID: 29423338
Published date: 2017
Circulating Dkk1 and TRAIL Are Associated With Cognitive Decline in Community-Dwelling, Older Adults With Cognitive Concerns.
Ross RD, Shah RC, Leurgans S, Bottligieri T, Wilson RS, Sumner DR
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (12):1688-1694. PubMed PMID: 29432613
Published date: 2018 Feb 08
The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex.
Jeanneteau F, Barre?re C, Vos M, De Vries CJM, Rouillard C, Levesque D, Dromard Y, Moisan MP, Duric V, Franklin TC, Duman RS, Lewis DA, Ginsberg SD, Arango-Lievano M
The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (6):1335-1350. PubMed PMID: 29295823
Published date: 2018 Feb 07
A transcriptomic atlas of aged human microglia.
Olah M, Patrick E, Villani AC, Xu J, White CC, Ryan KJ, Piehowski P, Kapasi A, Nejad P, Cimpean M, Connor S, Yung CJ, Frangieh M, McHenry A, Elyaman W, Petyuk V, Schneider JA, Bennett DA, De Jager PL, Bradshaw EM
Nature communications 9 (1):539. PubMed PMID: 29416036
Published date: 2018 Feb 07
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.
Bennett RE, Robbins AB, Hu M, Cao X, Betensky RA, Clark T, Das S, Hyman BT
Proceedings of the National Academy of Sciences of the United States of America 115 (6):E1289-E1298. PubMed PMID: 29358399
Published date: 2018 02 06
CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P
Neurology. Genetics 4 (1):e216. PubMed PMID: 29473050
Published date: 2018 Feb
Treated hypothyroidism is associated with cerebrovascular disease but not Alzheimer's disease pathology in older adults.
Brenowitz WD, Han F, Kukull WA, Nelson PT
Neurobiology of aging. PubMed PMID: 29107848
Published date: 2018 02
Transitions across cognitive states and death among older adults in relation to education: A multistate survival model using data from six longitudinal studies.
Robitaille A, van den Hout A, Machado RJM, Bennett DA, C?ukic? I, Deary IJ, Hofer SM, Hoogendijk EO, Huisman M, Johansson B, Koval AV, van der Noordt M, Piccinin AM, Rijnhart JJM, Singh-Manoux A, Skoog J, Skoog I, Starr J, Vermunt L, Clouston S, Muniz Ter
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (4):462-472. PubMed PMID: 29396108
Published date: 2018 Jan 25
Evaluation of standardized and study-specific diffusion tensor imaging templates of the adult human brain: Template characteristics, spatial normalization accuracy, and detection of small inter-group
Zhang S, Arfanakis K
NeuroImage. PubMed PMID: 29414497
Published date: 2018 Jan 24
The Paradoxical Impact of Companionship on the Mental Health of Older African American Men.
Mitchell JA, Cadet T, Burke S, Williams ED, Alvarez D
The journals of gerontology. Series B, Psychological sciences and social sciences 73 (2):230-239. PubMed PMID: 28977531
Published date: 2018 01 11
Lack of Benefit With Idalopirdine for Alzheimer Disease: Another Therapeutic Failure in a Complex Disease Process.
Bennett DA
JAMA 319 (2):123-125. PubMed PMID: 29318261
Published date: 2018 01 09
Longitudinal patterns of potentially inappropriate medication use following incident dementia diagnosis.
Ramsey CM, Gnjidic D, Agogo GO, Allore H, Moga D
Alzheimer's & dementia (New York, N. Y.). PubMed PMID: 29296658
Published date: 2018
Population Neuroscience: Dementia Epidemiology Serving Precision Medicine and Population Health.
Ganguli M, Albanese E, Seshadri S, Bennett DA, Lyketsos C, Kukull WA, Skoog I, Hendrie HC
Alzheimer disease and associated disorders 32 (1):1-9. PubMed PMID: 29319603
Published date: 2018 Jan-Mar
Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimer's Disease.
Mahady L, Nadeem M, Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ
Journal of Alzheimer's disease : JAD 62 (1):115-131. PubMed PMID: 29439356
Published date: 2018
Best practices and lessons learned from reuse of 4 patient-derived metabolomics datasets in Alzheimer's disease.
Tenenbaum JD, Blach C
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. PubMed PMID: 29218889
Published date: 2018
Big Data Analytical Approaches to the NACC Dataset: Aiding Preclinical Trial Enrichment.
Lin M, Gong P, Yang T, Ye J, Albin RL, Dodge HH
Alzheimer disease and associated disorders 32 (1):18-27. PubMed PMID: 29227306
Published date: 2018 Jan-Mar
Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS).
Weintraub S, Besser L, Dodge HH, Teylan M, Ferris S, Goldstein FC, Giordani B, Kramer J, Loewenstein D, Marson D, Mungas D, Salmon D, Welsh-Bohmer K, Zhou XH, Shirk SD, Atri A, Kukull WA, Phelps C, Morris JC
Alzheimer disease and associated disorders 32 (1):10-17. PubMed PMID: 29240561
Published date: 2018 Jan-Mar
Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease.
Kirson NY, Scott Andrews J, Desai U, King SB, Schonfeld S, Birnbaum HG, Ball DE, Kahle-Wrobleski K
Journal of Alzheimer's disease : JAD 61 (1):295-307. PubMed PMID: 29154268
Published date: 2018
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, Jun G, Kunkle B, Kuzma A, Lee JJ, Lunetta KL, Ma Y, Martin E, Naj A, Nato AQ, Navas P, Nguy
Dementia and geriatric cognitive disorders 45 (1-2):1-17. PubMed PMID: 29486463
Published date: 2018
Neuropsychiatric Symptoms and the Diagnostic Stability of Mild Cognitive Impairment.
Sugarman MA, Alosco ML, Tripodis Y, Steinberg EG, Stern RA
Journal of Alzheimer's disease : JAD 62 (4):1841-1855. PubMed PMID: 29614641
Published date: 2018
Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease.
Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC
Journal of Alzheimer's disease : JAD 62 (4):1815-1826. PubMed PMID: 29614657
Published date: 2018
Pathologically Confirmed Alzheimer's Disease in APOE 2 Homozygotes is Rare but Does Occur.
Stipho F, Jackson R, Sabbagh MN
Journal of Alzheimer's disease : JAD 62 (4):1527-1530. PubMed PMID: 29562509
Published date: 2018
The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1.
Wang Q, Guo L, Thompson PM, Jack CR, Dodge H, Zhan L, Zhou J
Journal of Alzheimer's disease : JAD 64 (1):149-169. PubMed PMID: 29865049
Published date: 2018
A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology.
Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA
Journal of Alzheimer's disease : JAD 63 (4):1347-1360. PubMed PMID: 29843242
Published date: 2018
Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease.
Qian W, Fischer CE, Schweizer TA, Munoz DG
Current Alzheimer research 15 (2):187-194. PubMed PMID: 28847281
Published date: 2018
Dyslexic Characteristics of Chinese-Speaking Semantic Variant of Primary Progressive Aphasia.
Ting SKS, Foo H, Chia PS, Hameed S, Ng KP, Ng A, Kandiah N
The Journal of neuropsychiatry and clinical neurosciences 30 (1):31-37. PubMed PMID: 29061089
Published date: 2018 Winter
Decreasing hazards of Alzheimer's disease with the use of antidepressants: mitigating the risk of depression and apolipoprotein E.
Burke SL, Maramaldi P, Cadet T, Kukull W
International journal of geriatric psychiatry 33 (1):200-211. PubMed PMID: 28560728
Published date: 2018 Jan
Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.
Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C
Journal of Alzheimer's disease : JAD 64 (2):631-642. PubMed PMID: 29914016
Published date: 2018
Impact of the Presence of Select Cardiovascular Risk Factors on Cognitive Changes among Dementia Subtypes.
Irimata KE, Dugger BN, Wilson JR
Current Alzheimer research 15 (11):1032-1044. PubMed PMID: 29962344
Published date: 2018
Rapidly Progressive Alzheimer's Disease inTwo Distinct Autopsy Cohorts.
Pillai JA, Appleby BS, Safar J, Leverenz JB
Journal of Alzheimer's disease : JAD 64 (3):973-980. PubMed PMID: 29966195
Published date: 2018
Case-control studies of gene-environment interactions. When a case might not be the case.
Lobach I, Sampson J, Alekseyenko A, Lobach S, Zhang L
PloS one 13 (8):e0201140. PubMed PMID: 30133451
Published date: 2018
Ezrin Expression is Increased During Disease Progression in a Tauopathy Mouse Model and Alzheimer's Disease.
Vega IE, Umstead A, Wygant CM, Beck JS, Counts SE
Current Alzheimer research 15 (12):1086-1095. PubMed PMID: 30101710
Published date: 2018
Bivariate Causal Discovery and Its Applications to Gene Expression and Imaging Data Analysis.
Jiao R, Lin N, Hu Z, Bennett DA, Jin L, Xiong M
Frontiers in genetics. PubMed PMID: 30233639
Published date: 2018
Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline.
Tasaki S, Gaiteri C, Mostafavi S, Yu L, Wang Y, De Jager PL, Bennett DA
Frontiers in genetics. PubMed PMID: 30140277
Published date: 2018
Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies.
Hadjichrysanthou C, McRae-McKee K, Evans S, de Wolf F, Anderson RM
Journal of Alzheimer's disease : JAD 66 (2):587-600. PubMed PMID: 30320573
Published date: 2018
Traumatic Brain Injury and Age of Onset of Dementia with Lewy Bodies.
Nguyen TP, Schaffert J, LoBue C, Womack KB, Hart J, Cullum CM
Journal of Alzheimer's disease : JAD 66 (2):717-723. PubMed PMID: 30320582
Published date: 2018
The Association Between Body Mass Index, and Cognitive, Functional, and Behavioral Declines for Incident Dementia.
Michaud TL, Siahpush M, Farazi PA, Kim J, Yu F, Su D, Murman DL
Journal of Alzheimer's disease : JAD 66 (4):1507-1517. PubMed PMID: 30412484
Published date: 2018
Estimating the monetary benefits of medicare eligibility for reducing the symptoms of dementia.
Brent RJ
Applied economics 50 (58):6327-6340. PubMed PMID: 30344332
Published date: 2018
The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia.
Tasaki S, Gaiteri C, Mostafavi S, De Jager PL, Bennett DA
Frontiers in neuroscience. PubMed PMID: 30349450
Published date: 2018
Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly.
Lee S, Zhou X, Gao Y, Vardarajan B, Reyes-Dumeyer D, Rajan KB, Wilson RS, Evans DA, Besser LM, Kukull WA, Bennett DA, Brickman AM, Schupf N, Mayeux R, Barral S
PloS one 13 (11):e0206803. PubMed PMID: 30462667
Published date: 2018
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
Peloso GM, van der Lee SJ, Destefano AL, Seshardi S
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 30422133
Published date: 2018
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.
Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eri
Psychosomatic medicine 80 (3):242-251. PubMed PMID: 29280852
Published date: 2017 Dec 27
Ex-vivo quantitative susceptibility mapping of human brain hemispheres.
Evia AM, Kotrotsou A, Tamhane AA, Dawe RJ, Kapasi A, Leurgans SE, Schneider JA, Bennett DA, Arfanakis K
PloS one 12 (12):e0188395. PubMed PMID: 29261693
Published date: 2017
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM
Science translational medicine. PubMed PMID: 29263232
Published date: 2017 Dec 20
Person-specific contribution of neuropathologies to cognitive loss in old age.
Boyle PA, Yu L, Wilson RS, Leurgans SE, Schneider JA, Bennett DA
Annals of neurology 83 (1):74-83. PubMed PMID: 29244218
Published date: 2017 Dec 15
Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.
Peera Kommaddi R, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, Shaw E, Bennett DA, Nair D, Ravindranath V
The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (5):1085-1099. PubMed PMID: 29246925
Published date: 2017 Dec 15
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J
Nature 552 (7684):187-193. PubMed PMID: 29211722
Published date: 2017 12 14
Inventory of real world data sources in Parkinson's disease.
Tanguy A, Jo?nsson L, Ishihara L
BMC neurology 17 (1):213. PubMed PMID: 29216834
Published date: 2017 Dec 08
Validation and diagnostic accuracy of predictive curves for age-associated longitudinal cognitive decline in older adults.
Bernier PJ, Gourdeau C, Carmichael PH, Beauchemin JP, Verreault R, Bouchard RW, Krger E, Laforce R
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 189 (48):E1472-E1480. PubMed PMID: 29203616
Published date: 2017 Dec 04
A variant in PPP4R3A protects against alzheimer-related metabolic decline.
Christopher L, Napolioni V, Khan RR, Han SS, Greicius MD
Annals of neurology 82 (6):900-911. PubMed PMID: 29130521
Published date: 2017 Dec
Mental speed is associated with the shape irregularity of white matter MRI hyperintensity load.
Lange C, Suppa P, Murer A, Ritter K, Pietrzyk U, Steinhagen-Thiessen E, Fiebach JB, Spies L, Buchert R
Brain imaging and behavior 11 (6):1720-1730. PubMed PMID: 27796731
Published date: 2017 Dec
Moderating risk of Alzheimer's disease through the use of anxiolytic agents.
Burke SL, O'Driscoll J, Alcide A, Li T
International journal of geriatric psychiatry 32 (12):1312-1321. PubMed PMID: 27805724
Published date: 2017 12
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan
Acta neuropathologica 135 (1):85-93. PubMed PMID: 29177679
Published date: 2017 Nov 24
Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study.
Klaver AC, Coffey MP, Bennett DA, Loeffler DA
Translational neurodegeneration. PubMed PMID: 29204273
Published date: 2017
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL
Stem cell reports 9 (6):1868-1884. PubMed PMID: 29153990
Published date: 2017 Nov 13
Neuropathological and transcriptomic characteristics of the aged brain.
Miller JA, Guillozet-Bongaarts A, Gibbons LE, Postupna N, Renz A, Beller AE, Sunkin SM, Ng L, Rose SE, Smith KA, Szafer A, Barber C, Bertagnolli D, Bickley K, Brouner K, Caldejon S, Chapin M, Chua ML, Coleman NM, Cudaback E, Cuhaciyan C, Dalley RA, Dee N,
eLife. PubMed PMID: 29120328
Published date: 2017 11 09
Alzheimer's Disease-Related Dementias Summit 2016: National research priorities.
Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, Marder KS, Moy CS, Phelps CH, Scott PA, Seeley WW, Sieber BA, Silverberg NB, Su
Neurology 89 (23):2381-2391. PubMed PMID: 29117955
Published date: 2017 Nov 08
Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA
JAMA neurology 74 (12):1473-1480. PubMed PMID: 29084334
Published date: 2017 Oct 30
Genetic influence of plasma homocysteine on Alzheimer's disease.
Roostaei T, Felsky D, Nazeri A, De Jager PL, Schneider JA, Bennett DA, Voineskos AN
Neurobiology of aging. PubMed PMID: 29102475
Published date: 2017 Oct 13
Traumatic brain injury may not increase the risk of Alzheimer disease.
Weiner MW, Crane PK, Montine TJ, Bennett DA, Veitch DP
Neurology 89 (18):1923-1925. PubMed PMID: 28978654
Published date: 2017 Oct 04
Ultra-rare mutations in SRCAP segregate in Caribbean Hispanic families with Alzheimer disease.
Vardarajan BN, Tosto G, Lefort R, Yu L, Bennett DA, De Jager PL, Barral S, Reyes-Dumeyer D, Nagy PL, Lee JH, Cheng R, Medrano M, Lantigua R, Rogaeva E, St George-Hyslop P, Mayeux R
Neurology. Genetics 3 (5):e178. PubMed PMID: 28852706
Published date: 2017 Oct
Societal and Family Lifetime Cost of Dementia: Implications for Policy.
Jutkowitz E, Kane RL, Gaugler JE, MacLehose RF, Dowd B, Kuntz KM
Journal of the American Geriatrics Society 65 (10):2169-2175. PubMed PMID: 28815557
Published date: 2017 Oct
Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis.
Neu SC, Pa J, Kukull W, Beekly D, Kuzma A, Gangadharan P, Wang LS, Romero K, Arneric SP, Redolfi A, Orlandi D, Frisoni GB, Au R, Devine S, Auerbach S, Espinosa A, Boada M, Ruiz A, Johnson SC, Koscik R, Wang JJ, Hsu WC, Chen YL, Toga AW
JAMA neurology 74 (10):1178-1189. PubMed PMID: 28846757
Published date: 2017 10 01
Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data.
Sano M, Zhu CW, Grossman H, Schimming C
Journal of the American Geriatrics Society 65 (10):2198-2204. PubMed PMID: 28771679
Published date: 2017 Oct
Personality Predicts Mortality Risk: An Integrative Data Analysis of 15 International Longitudinal Studies.
Graham EK, Rutsohn JP, Turiano NA, Bendayan R, Batterham PJ, Gerstorf D, Katz MJ, Reynolds CA, Sharp ES, Yoneda TB, Bastarache ED, Elleman LG, Zelinski EM, Johansson B, Kuh D, Barnes LL, Bennett DA, Deeg DJH, Lipton RB, Pedersen NL, Piccinin AM, Spiro A,
Journal of research in personality. PubMed PMID: 29230075
Published date: 2017 Oct
Age and the association of dementia-related pathology with trajectories of cognitive decline.
Jansen WJ, Wilson RS, Visser PJ, Nag S, Schneider JA, James BD, Leurgans SE, Capuano AW, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29078129
Published date: 2017 Sep 05
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
Ng B, White CC, Klein HU, Sieberts SK, McCabe C, Patrick E, Xu J, Yu L, Gaiteri C, Bennett DA, Mostafavi S, De Jager PL
Nature neuroscience 20 (10):1418-1426. PubMed PMID: 28869584
Published date: 2017 Sep 04
Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia.
Goldstein FC, Steenland K, Zhao L, Wharton W, Levey AI, Hajjar I
Journal of the American Geriatrics Society 65 (9):1969-1974. PubMed PMID: 28590010
Published date: 2017 Sep
Cognitive decline associated with pathological burden in primary age-related tauopathy.
Jefferson-George KS, Wolk DA, Lee EB, McMillan CT
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (9):1048-1053. PubMed PMID: 28322204
Published date: 2017 Sep
Detecting clinical change with the CDR-FTLD: differences between FTLD and AD dementia.
Mioshi E, Flanagan E, Knopman D
International journal of geriatric psychiatry 32 (9):977-982. PubMed PMID: 27464599
Published date: 2017 09
Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia.
Weuve J, Barnes LL, de Leon CFM, Rajan KB, Beck T, Aggarwal NT, Hebert LE, Bennett DA, Wilson RS, Evans DA
Epidemiology (Cambridge, Mass.) 29 (1):151-159. PubMed PMID: 28863046
Published date: 2017 Aug 31
Performance comparison of 10 different classification techniques in segmenting white matter hyperintensities in aging.
Dadar M, Maranzano J, Misquitta K, Anor CJ, Fonov VS, Tartaglia MC, Carmichael OT, Decarli C, Collins DL
NeuroImage. PubMed PMID: 28602597
Published date: 2017 08 15
Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.
Barbash S, Simchovitz A, Buchman AS, Bennett DA, Shifman S, Soreq H
Translational psychiatry 7 (8):e1199. PubMed PMID: 28786976
Published date: 2017 Aug 08
Body Mass Index and Decline in Cognitive Function in Older Black and White Persons.
Arvanitakis Z, Capuano AW, Bennett DA, Barnes LL
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (2):198-203. PubMed PMID: 28961897
Published date: 2017 Aug 07
UNC5C variants are associated with cerebral amyloid angiopathy.
Yang HS, White CC, Chibnik LB, Klein HU, Schneider JA, Bennett DA, De Jager PL
Neurology. Genetics 3 (4):e176. PubMed PMID: 28761931
Published date: 2017 Aug
Impact of multiple pathologies on the threshold for clinically overt dementia.
Kapasi A, DeCarli C, Schneider JA
Acta neuropathologica 134 (2):171-186. PubMed PMID: 28488154
Published date: 2017 Aug
Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in Prodromal Alzheimer Disease.
Perez SE, Nadeem M, Malek-Ahmadi MH, He B, Mufson EJ
Neuro-degenerative diseases 17 (6):235-241. PubMed PMID: 28743126
Published date: 2017 Jul 26
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P,
Nature genetics 49 (9):1373-1384. PubMed PMID: 28714976
Published date: 2017 Jul 17
APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Yang J, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
PloS one 12 (7):e0180356. PubMed PMID: 28672022
Published date: 2017
Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
Patrick E, Rajagopal S, Wong HA, McCabe C, Xu J, Tang A, Imboywa SH, Schneider JA, Pochet N, Krichevsky AM, Chibnik LB, Bennett DA, De Jager PL
Molecular neurodegeneration 12 (1):51. PubMed PMID: 28668092
Published date: 2017 Jul 01
Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease.
Mi Z, Abrahamson EE, Ryu AY, Fish KN, Sweet RA, Mufson EJ, Ikonomovic MD
Neurobiology of aging. PubMed PMID: 28259365
Published date: 2017 Jul
Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.
Monsell SE, Mock C, Fardo DW, Bertelsen S, Cairns NJ, Roe CM, Ellingson SR, Morris JC, Goate AM, Kukull WA
Alzheimer disease and associated disorders 31 (3):232-238. PubMed PMID: 27849641
Published date: 2017 Jul-Sep
Neuropsychological Testing in Pathologically Verified Alzheimer Disease and Frontotemporal Dementia: How Well Do the Uniform Data Set Measures Differentiate Between Diseases?
Ritter AR, Leger GC, Miller JB, Banks SJ
Alzheimer disease and associated disorders 31 (3):187-191. PubMed PMID: 28005562
Published date: 2017 Jul-Sep
Preventing Cognitive Decline and Dementia: A Way Forward
Downey A, Stroud C, Landis S, Leshner AI
null 84 (1):78-88. PubMed PMID: 28650595
Published date: 2017 06 22
Alzheimer's brains show inter-related changes in RNA and lipid metabolism.
Barbash S, Garfinkel BP, Maoz R, Simchovitz A, Nadorp B, Guffanti A, Bennett ER, Nadeau C, Tu?rk A, Paul L, Reda T, Li Y, Buchman AS, Greenberg DS, Seitz A, Bennett DA, Giavalisco P, Soreq H
Neurobiology of disease. PubMed PMID: 28630030
Published date: 2017 Jun 16
Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 9 (12):430. PubMed PMID: 28624335
Published date: 2017 Jun 15
A Dopamine Receptor genetic variant enhances perceptual speed in cognitive healthy subjects.
Barral S, Habeck C, Gazes E, De Jager PL, Bennett DA, Stern Y
Alzheimer's & dementia (New York, N. Y.) 3 (2):254-261. PubMed PMID: 28993814
Published date: 2017 Jun
Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease.
Perez SE, Nadeem M, He B, Miguel JC, Malek-Ahmadi MH, Chen K, Mufson EJ
Neurobiology of aging. PubMed PMID: 28365005
Published date: 2017 Jun
Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample.
Brenowitz WD, Hubbard RA, Keene CD, Hawes SE, Longstreth WT, Woltjer RL, Kukull WA
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):654-662. PubMed PMID: 27870939
Published date: 2017 Jun
How Does Psychosocial Behavior Contribute to Cognitive Health in Old Age?
Wilson RS, Bennett DA
Brain sciences. PubMed PMID: 28545247
Published date: 2017 May 23
Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesne? SE
Proceedings of the National Academy of Sciences of the United States of America 114 (23):E4648-E4657. PubMed PMID: 28533388
Published date: 2017 May 22
Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.
Lu AT, Hannon E, Levine ME, Crimmins EM, Lunnon K, Mill J, Geschwind DH, Horvath S
Nature communications. PubMed PMID: 28516910
Published date: 2017 05 18
Cognitive Domain Dispersion Association with Alzheimer's Disease Pathology.
Malek-Ahmadi M, Lu S, Chan Y, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease : JAD 58 (2):575-583. PubMed PMID: 28453479
Published date: 2017
Effects of Delay Duration on the WMS Logical Memory Performance of Older Adults with Probable Alzheimer's Disease, Probable Vascular Dementia, and Normal Cognition.
Montgomery V, Harris K, Stabler A, Lu LH
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 32 (3):375-380. PubMed PMID: 28431036
Published date: 2017 May 01
Neurofibrillary Tangle Stage and the Rate of Progression of Alzheimer Symptoms: Modeling Using an Autopsy Cohort and Application to Clinical Trial Design.
Qian J, Hyman BT, Betensky RA
JAMA neurology 74 (5):540-548. PubMed PMID: 28288263
Published date: 2017 05 01
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemensc
Acta neuropathologica 133 (5):839-856. PubMed PMID: 28247064
Published date: 2017 May
Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease.
Counts SE, Mufson EJ
Cell transplantation 26 (4):693-702. PubMed PMID: 27938491
Published date: 2017 Apr 13
Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.
Ahmad F, Singh K, Das D, Gowaikar R, Shaw E, Ramachandran A, Rupanagudi KV, Kommaddi RP, Bennett DA, Ravindranath V
Antioxidants & redox signaling 27 (16):1269-1280. PubMed PMID: 28264587
Published date: 2017 Apr 12
Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
Lim AS, Klein HU, Yu L, Chibnik LB, Ali S, Xu J, Bennett DA, De Jager PL
Nature communications. PubMed PMID: 28368004
Published date: 2017 Apr 03
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL
PLoS medicine 14 (4):e1002287. PubMed PMID: 28441426
Published date: 2017 Apr
Older Rural- and Urban-Dwelling Appalachian Adults With Mild Cognitive Impairment.
Mattos MK, Snitz BE, Lingler JH, Burke LE, Novosel LM, Sereika SM
The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association 33 (2):208-216. PubMed PMID: 27509183
Published date: 2017 04
Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.
Yu L, Dawe RJ, Buchman AS, Boyle PA, Schneider JA, Arfanakis K, Bennett DA
Behavioural brain research 322 (Pt B):233-240. PubMed PMID: 27596378
Published date: 2017 Mar 30
Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
Chibnik LB, White CC, Mukherjee S, Raj T, Yu L, Larson EB, Montine TJ, Keene CD, Sonnen J, Schneider JA, Crane PK, Shulman JM, Bennett DA, De Jager PL
Molecular psychiatry 23 (6):1521-1529. PubMed PMID: 28322283
Published date: 2017 Mar 21
Polygenic risk scores in familial Alzheimer disease.
Tosto G, Bird TD, Tsuang D, Bennett DA, Boeve BF, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Bertlesen S, Graff-Radford NR, Medrano M, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R
Neurology 88 (12):1180-1186. PubMed PMID: 28213371
Published date: 2017 Mar 21
Genetic epistasis regulates amyloid deposition in resilient aging.
Felsky D, Xu J, Chibnik LB, Schneider JA, Knight J, Kennedy JL, Bennett DA, De Jager PL, Voineskos AN
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (10):1107-1116. PubMed PMID: 28322202
Published date: 2017 Mar 17
Predictors That a Diagnosis of Mild Cognitive Impairment Will Remain Stable 3 Years Later.
Clem MA, Holliday RP, Pandya S, Hynan LS, Lacritz LH, Woon FL
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 30 (1):8-15. PubMed PMID: 28323681
Published date: 2017 03
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Va
PLoS medicine 14 (3):e1002258. PubMed PMID: 28323831
Published date: 2017 03
Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery.
Bennett DA
PLoS medicine 14 (3):e1002256. PubMed PMID: 28291788
Published date: 2017 Mar
Author response: Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Bennett DA
Neurology 88 (9):919-920. PubMed PMID: 28242851
Published date: 2017 Feb 28
Author response: Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Bennett DA
Neurology 88 (9):920. PubMed PMID: 28242853
Published date: 2017 Feb 28
Outcomes after diagnosis of mild cognitive impairment in a large autopsy series.
Abner EL, Kryscio RJ, Schmitt FA, Fardo DW, Moga DC, Ighodaro ET, Jicha GA, Yu L, Dodge HH, Xiong C, Woltjer RL, Schneider JA, Cairns NJ, Bennett DA, Nelson PT
Annals of neurology 81 (4):549-559. PubMed PMID: 28224671
Published date: 2017 Feb 22
Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease.
Geifman N, Brinton RD, Kennedy RE, Schneider LS, Butte AJ
Alzheimer's research & therapy 9 (1):10. PubMed PMID: 28212683
Published date: 2017 Feb 17
TOMM40'523 variant and cognitive decline in older persons with APOE ?3/3 genotype.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
Neurology 88 (7):661-668. PubMed PMID: 28108637
Published date: 2017 Feb 14
TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD.
Nag S, Yu L, Wilson RS, Chen EY, Bennett DA, Schneider JA
Neurology 88 (7):653-660. PubMed PMID: 28087828
Published date: 2017 Feb 14
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (7):727-738. PubMed PMID: 28183528
Published date: 2017 Feb 06
Genetic architecture of age-related cognitive decline in African Americans.
Raj T, Chibnik LB, McCabe C, Wong A, Replogle JM, Yu L, Gao S, Unverzagt FW, Stranger B, Murrell J, Barnes L, Hendrie HC, Foroud T, Krichevsky A, Bennett DA, Hall KS, Evans DA, De Jager PL
Neurology. Genetics 3 (1):e125. PubMed PMID: 28078323
Published date: 2017 Feb
Walking Pace and the Risk of Cognitive Decline and Dementia in Elderly Populations: A Meta-analysis of Prospective Cohort Studies.
Quan M, Xun P, Chen C, Wen J, Wang Y, Wang R, Chen P, He K
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (2):266-270. PubMed PMID: 27927757
Published date: 2017 02
Risk Factors Associated With Cognitive, Functional, and Behavioral Trajectories of Newly Diagnosed Dementia Patients.
Jutkowitz E, MacLehose RF, Gaugler JE, Dowd B, Kuntz KM, Kane RL
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (2):251-258. PubMed PMID: 27129917
Published date: 2017 02
Association of Neuropathological Markers in the Parietal Cortex With Antemortem Cognitive Function in Persons With Mild Cognitive Impairment and Alzheimer Disease.
Tremblay C, Franc?ois A, Delay C, Freland L, Vandal M, Bennett DA, Calon F
Journal of neuropathology and experimental neurology 76 (2):70-88. PubMed PMID: 28158844
Published date: 2017 Jan 31
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease.
Kelly SC, He B, Perez SE, Ginsberg SD, Mufson EJ, Counts SE
Acta neuropathologica communications 5 (1):8. PubMed PMID: 28109312
Published date: 2017 Jan 21
Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study.
McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe RS, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG, Beilin LJ, Donnan GA, Gibb
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (11):1586-1593. PubMed PMID: 28329340
Published date: 2017 Jan 20
Novel genetic loci associated with hippocampal volume.
Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivie?res S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Be
Nature communications. PubMed PMID: 28098162
Published date: 2017 Jan 18
Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline.
Boyle PA, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Wilson RS, Bennett DA
Brain : a journal of neurology 140 (3):804-812. PubMed PMID: 28082297
Published date: 2017 Jan 12
The complex genetics of gait speed: genome-wide meta-analysis approach.
Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JA, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, P
Aging 9 (1):209-246. PubMed PMID: 28077804
Published date: 2017 Jan 10
A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
Zhao J, Zhu Y, Yang J, Li L, Wu H, De Jager PL, Jin P, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):674-688. PubMed PMID: 28089213
Published date: 2017 Ju n
Risk Factors and Pathological Substrates Associated with Agitation/Aggression in Alzheimer's Disease: A Preliminary Study using NACC Data.
Sennik S, Schweizer TA, Fischer CE, Munoz DG
Journal of Alzheimer's disease : JAD 55 (4):1519-1528. PubMed PMID: 27911311
Published date: 2017
A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer's Disease in the US and Finland.
Moga DC, Taipale H, Tolppanen AM, Tanskanen A, Tiihonen J, Hartikainen S, Wu Q, Jicha GA, Gnjidic D
Drugs & aging 34 (1):55-65. PubMed PMID: 27896799
Published date: 2017 01
Traumatic brain injury history is associated with earlier age of onset of Alzheimer disease.
LoBue C, Wadsworth H, Wilmoth K, Clem M, Hart J, Womack KB, Didehbani N, Lacritz LH, Rossetti HC, Cullum CM
The Clinical neuropsychologist 31 (1):85-98. PubMed PMID: 27855547
Published date: 2017 01
Impact of Functional Deficits in Instrumental Activities of Daily Living in Mild Cognitive Impairment: A Clinical Algorithm to Predict Progression to Dementia.
Devanand DP, Liu X, Brown PJ
Alzheimer disease and associated disorders 31 (1):55-61. PubMed PMID: 27819843
Published date: 2017 Jan-Mar
The Role of Cerebrovascular Disease on Cognitive and Functional Status and Psychosis in Severe Alzheimer's Disease.
Kim J, Schweizer TA, Fischer CE, Munoz DG
Journal of Alzheimer's disease : JAD 55 (1):381-389. PubMed PMID: 27662301
Published date: 2017
The Relationship Between Cognitive Functioning and the JNC-8 Guidelines for Hypertension in Older Adults.
Goldstein FC, Hajjar IM, Dunn CB, Levey AI, Wharton W
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (1):121-126. PubMed PMID: 27678289
Published date: 2017 01
Biomarkers for the Early Detection and Progression of Alzheimer's Disease.
Counts SE, Ikonomovic MD, Mercado N, Vega IE, Mufson EJ
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 14 (1):35-53. PubMed PMID: 27738903
Published date: 2017 Jan
Executive Dysfunction and Behavioral Symptoms Are Associated with Deficits in Instrumental Activities of Daily Living in Frontotemporal Dementia.
Moheb N, Mendez MF, Kremen SA, Teng E
Dementia and geriatric cognitive disorders 43 (1-2):89-99. PubMed PMID: 28103593
Published date: 2017
Gender and Pathology-Specific Effect of Apolipoprotein E Genotype on Psychosis in Alzheimer's Disease.
Kim J, Fischer CE, Schweizer TA, Munoz DG
Current Alzheimer research 14 (8):834-840. PubMed PMID: 28219318
Published date: 2017
Perceived Stress and Cognitive Decline in Different Cognitive Domains in a Cohort of Older African Americans.
Turner AD, James BD, Capuano AW, Aggarwal NT, Barnes LL
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 25 (1):25-34. PubMed PMID: 28231871
Published date: 2017 Jan
Predictors of Reversion from Mild Cognitive Impairment to Normal Cognition.
Pandya SY, Lacritz LH, Weiner MF, Deschner M, Woon FL
Dementia and geriatric cognitive disorders 43 (3-4):204-214. PubMed PMID: 28301848
Published date: 2017
Bladder antimuscarinics and cognitive decline in elderly patients.
Moga DC, Abner EL, Wu Q, Jicha GA
Alzheimer's & dementia (New York, N. Y.) 3 (1):139-148. PubMed PMID: 28462390
Published date: 2017 Jan
The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia.
Tripodis Y, Alosco ML, Zirogiannis N, Gavett BE, Chaisson C, Martin B, McClean MD, Mez J, Kowall N, Stern RA
Journal of Alzheimer's disease : JAD 59 (1):251-263. PubMed PMID: 28655133
Published date: 2017
Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology.
Yarchoan M, James BD, Shah RC, Arvanitakis Z, Wilson RS, Schneider J, Bennett DA, Arnold SE
Journal of Alzheimer's disease : JAD 56 (2):699-706. PubMed PMID: 28035936
Published date: 2016 Dec 30
Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease.
Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye JA, Lyons DE, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA, Kryscio RJ, Abner EL
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):613-623. PubMed PMID: 28017827
Published date: 2016 Dec 23
Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.
Hill WD, Davies G, Harris SE, Hagenaars SP, Liewald DC, Penke L, Gale CR, Deary IJ
Translational psychiatry 6 (12):e980. PubMed PMID: 27959336
Published date: 2016 Dec 13
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttensch?n HN, Byrne EM, B?rglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E,
Biological psychiatry 82 (5):322-329. PubMed PMID: 28049566
Published date: 2016 Dec 08
A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Carrasquillo MM, Allen M, Burgess JD, Wang X, Strickland SL, Aryal S, Siuda J, Kachadoorian ML, Medway C, Younkin CS, Nair A, Wang C, Chanana P, Serie D, Nguyen T, Lincoln S, Malphrus KG, Morgan K, Golde TE, Price ND, White CC, De Jager PL, Bennett DA, As
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):663-673. PubMed PMID: 27939925
Published date: 2016 Dec 08
Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.
Foveau B, Albrecht S, Bennett DA, Correa JA, LeBlanc AC
Acta neuropathologica communications 4 (1):127. PubMed PMID: 27931265
Published date: 2016 Dec 08
Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults.
Buchman NM, Leurgans SE, Shah RJ, VanderHorst V, Wilson RS, Bachner YG, Tanne D, Schneider JA, Bennett DA, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (9):1295-1301. PubMed PMID: 27927762
Published date: 2016 Dec 07
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.
Bordi M, Berg MJ, Mohan PS, Peterhoff CM, Alldred MJ, Che S, Ginsberg SD, Nixon RA
Autophagy 12 (12):2467-2483. PubMed PMID: 27813694
Published date: 2016 12
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteri?a ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivie?res S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Arms
Nature neuroscience 19 (12):1569-1582. PubMed PMID: 27694991
Published date: 2016 Dec
Subtle changes in daily functioning predict conversion from normal to mild cognitive impairment or dementia: an analysis of the NACC database.
Nowrangi MA, Rosenberg PB, Leoutsakos JS
International psychogeriatrics 28 (12):2009-2018. PubMed PMID: 27585497
Published date: 2016 12
Clinicopathological correlates of depression in early Alzheimer's disease in the NACC.
McCutcheon ST, Han D, Troncoso J, Koliatsos VE, Albert M, Lyketsos CG, Leoutsakos JS
International journal of geriatric psychiatry 31 (12):1301-1311. PubMed PMID: 26876501
Published date: 2016 12
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linne?r RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonza
Nature genetics 48 (12):1591. PubMed PMID: 27898078
Published date: 2016 Nov 29
Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
Dong J, Wyss A, Yang J, Price TR, Nicolas A, Nalls M, Tranah G, Franceschini N, Xu Z, Schulte C, Alonso A, Cummings SR, Fornage M, Zaykin D, Li L, Huang X, Kritchevsky S, Liu Y, Gasser T, Wilson RS, De Jager PL, Singleton AB, Pinto JM, Harris T, Mosley TH
Molecular neurobiology 54 (10):8021-8032. PubMed PMID: 27878761
Published date: 2016 Nov 23
Genetic variants linked to education predict longevity.
Marioni RE, Ritchie SJ, Joshi PK, Hagenaars SP, Okbay A, Fischer K, Adams MJ, Hill WD, Davies G, Nagy R, Amador C, La?ll K, Metspalu A, Liewald DC, Campbell A, Wilson JF, Hayward C, Esko T, Porteous DJ, Gale CR, Deary IJ
Proceedings of the National Academy of Sciences of the United States of America 113 (47):13366-13371. PubMed PMID: 27799538
Published date: 2016 Nov 22
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1.
Cronin P, McCarthy MJ, Lim AS, Salmon DP, Galasko D, Masliah E, De Jager PL, Bennett DA, Desplats P
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):689-700. PubMed PMID: 27883893
Published date: 2016 Nov 21
Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology.
Arango-Lievano M, Peguet C, Catteau M, Parmentier ML, Wu S, Chao MV, Ginsberg SD, Jeanneteau F
Scientific reports. PubMed PMID: 27849045
Published date: 2016 11 16
Addendum: REST and stress resistance in ageing and Alzheimer's disease.
T L, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaia?covo MP, Yankner BA
Nature 540 (7633):470. PubMed PMID: 27851730
Published date: 2016 Nov 16
The effectiveness and unique contribution of neuropsychological tests and the latent phenotype in the differential diagnosis of dementia in the uniform data set.
John SE, Gurnani AS, Bussell C, Saurman JL, Griffin JW, Gavett BE
Neuropsychology 30 (8):946-960. PubMed PMID: 27797542
Published date: 2016 11
Anticholinergic Drug Use and Risk to Cognitive Performance in Older Adults with Questionable Cognitive Impairment: A Cross-Sectional Analysis.
Swami S, Cohen RA, Kairalla JA, Manini TM
Drugs & aging 33 (11):809-818. PubMed PMID: 27638818
Published date: 2016 11
Willingness to Be a Brain Donor: A Survey of Research Volunteers From 4 Racial/Ethnic Groups.
Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC
Alzheimer disease and associated disorders 31 (2):135-140. PubMed PMID: 27779492
Published date: 2016 Oct 24
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ, Haines JL
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (2):119-129. PubMed PMID: 27770636
Published date: 2016 Oct 20
The characteristics of astrocyte on Aβ clearance altered in Alzheimer's disease were reversed by anti-inflammatory agent (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate.
Liu RX, Huang C, Bennett DA, Li H, Wang R
American journal of translational research 8 (10):4082-4094. PubMed PMID: 27829994
Published date: 2016
White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age.
Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA
Annals of clinical and translational neurology 3 (10):791-800. PubMed PMID: 27752514
Published date: 2016 Oct
TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
James BD, Wilson RS, Boyle PA, Trojanowski JQ, Bennett DA, Schneider JA
Brain : a journal of neurology 139 (11):2983-2993. PubMed PMID: 27694152
Published date: 2016 Sep 30
Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model.
Do Carmo S, Hanzel CE, Jacobs ML, Machnes Z, Iulita MF, Yang J, Yu L, Ducatenzeiler A, Danik M, Breuillaud LS, Bennett DA, Szyf M, Cuello AC
Scientific reports. PubMed PMID: 27681803
Published date: 2016
Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gu?mu?s? ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF,
Nature neuroscience 19 (11):1442-1453. PubMed PMID: 27668389
Published date: 2016 Sep 26
Molecular and cellular pathophysiology of preclinical Alzheimer's disease.
Mufson EJ, Ikonomovic MD, Counts SE, Perez SE, Malek-Ahmadi M, Scheff SW, Ginsberg SD
Behavioural brain research. PubMed PMID: 27185734
Published date: 2016 Sep 15
Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
Sherman MA, LaCroix M, Amar F, Larson ME, Forster C, Aguzzi A, Bennett DA, Ramsden M, Lesne? SE
The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (37):9647-58. PubMed PMID: 27629715
Published date: 2016 Sep 14
Age-dependent effects of APOE 4 in preclinical Alzheimer's disease.
Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS
Annals of clinical and translational neurology 3 (9):668-77. PubMed PMID: 27648456
Published date: 2016 Sep
Incident Antipsychotic Use in a Diverse Population with Dementia.
Filshtein T, Beckett LA, Godwin H, Hinton L, Xiong GL
Journal of the American Geriatrics Society 64 (9):e44-6. PubMed PMID: 27430431
Published date: 2016 09
Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly.
Mi Z, Halfter W, Abrahamson EE, Klunk WE, Mathis CA, Mufson EJ, Ikonomovic MD
Journal of neuropathology and experimental neurology 75 (9):868-76. PubMed PMID: 27444354
Published date: 2016 Sep
Phenotypic Similarities Between Late-Onset Autosomal Dominant and Sporadic Alzheimer Disease: A Single-Family Case-Control Study.
Day GS, Musiek ES, Roe CM, Norton J, Goate AM, Cruchaga C, Cairns NJ, Morris JC
JAMA neurology 73 (9):1125-32. PubMed PMID: 27454811
Published date: 2016 09 01
The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
Klein HU, Bennett DA, De Jager PL
Acta neuropathologica 132 (4):503-14. PubMed PMID: 27573688
Published date: 2016 Aug 29
Personality Polygenes, Positive Affect, and Life Satisfaction.
Weiss A, Baselmans BM, Hofer E, Yang J, Okbay A, Lind PA, Miller MB, Nolte IM, Zhao W, Hagenaars SP, Hottenga JJ, Matteson LK, Snieder H, Faul JD, Hartman CA, Boyle PA, Tiemeier H, Mosing MA, Pattie A, Davies G, Liewald DC, Schmidt R, De Jager PL, Heath A
Twin research and human genetics : the official journal of the International Society for Twin Studies 19 (5):1-11. PubMed PMID: 27546527
Published date: 2016 Aug 22
The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.
Tosto G, Bird TD, Bennett DA, Boeve BF, Brickman AM, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Graff-Radford NR, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R
JAMA neurology 73 (10):1231-1237. PubMed PMID: 27533593
Published date: 2016 Aug 15
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.
Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL
Genome biology 17 (1):171. PubMed PMID: 27511193
Published date: 2016 08 11
Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Leurgans SE, Yu L, Wilson RS, Lim AS, James BD, Shulman JM, Bennett DA
Neurology 87 (10):1036-44. PubMed PMID: 27488597
Published date: 2016 Aug 3
Reduced pCREB in Alzheimer's disease prefrontal cortex is reflected in peripheral blood mononuclear cells.
Bartolotti N, Bennett DA, Lazarov O
Molecular psychiatry 21 (9):1158-66. PubMed PMID: 27480489
Published date: 2016 Aug 2
Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, De Jager PL, Bradshaw EM
Neurology. Genetics 2 (4):e90. PubMed PMID: 27504496
Published date: 2016 Aug
Traumatic brain injury history is associated with earlier age of onset of frontotemporal dementia.
LoBue C, Wilmoth K, Cullum CM, Rossetti HC, Lacritz LH, Hynan LS, Hart J, Womack KB
Journal of neurology, neurosurgery, and psychiatry 87 (8):817-20. PubMed PMID: 26359171
Published date: 2016 08
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Valenca GT, Srivastava GP, Oliveira-Filho J, White CC, Yu L, Schneider JA, Buchman AS, Shulman JM, Bennett DA, De Jager PL
PloS one 11 (7):e0157452. PubMed PMID: 27458716
Published date: 2016
Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly.
Malek-Ahmadi M, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease : JAD 53 (4):1641-52. PubMed PMID: 27540968
Published date: 2016 Jul 14
Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings.
Crane PK, Gibbons LE, Dams-O'Connor K, Trittschuh E, Leverenz JB, Keene CD, Sonnen J, Montine TJ, Bennett DA, Leurgans S, Schneider JA, Larson EB
JAMA neurology 73 (9):1062-9. PubMed PMID: 27400367
Published date: 2016 Jul 11
Neuropsychiatric symptoms and Apolipoprotein E: Associations with eventual Alzheimer's disease development.
Burke SL, Maramaldi P, Cadet T, Kukull W
Archives of gerontology and geriatrics. PubMed PMID: 27111252
Published date: 2016 Jul-Aug
Braak stage and trajectory of cognitive decline in noncognitively impaired elders.
Mufson EJ, Malek-Ahmadi M, Snyder N, Ausdemore J, Chen K, Perez SE
Neurobiology of aging. PubMed PMID: 27255819
Published date: 2016 Jul
Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Farfel JM, Yu L, Buchman AS, Schneider JA, De Jager PL, Bennett DA
Neurology 87 (5):489-96. PubMed PMID: 27371493
Published date: 2016 Jul 1
A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers.
Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B
Neurology 87 (5):539-47. PubMed PMID: 27371494
Published date: 2016 Jul 1
Predicting the progression of Alzheimer's disease dementia: Amultidomain health policy model.
Green C, Zhang S
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (7):776-85. PubMed PMID: 27016691
Published date: 2016 07
A Cross-Sectional Analysis of Late-Life Cardiovascular Factors and Their Relation to Clinically Defined Neurodegenerative Diseases.
Dugger BN, Malek-Ahmadi M, Monsell SE, Kukull WA, Woodruff BK, Reiman EM, Beach TG, Wilson J
Alzheimer disease and associated disorders 30 (3):223-9. PubMed PMID: 26756386
Published date: 2016 Jul-Sep
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Ev
Aging cell 15 (5):792-800. PubMed PMID: 27325353
Published date: 2016 Jun 21
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.
Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF,
Journal of Alzheimer's disease : JAD 53 (3):921-32. PubMed PMID: 27340842
Published date: 2016 Jun 18
Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study.
Arvanitakis Z, Capuano AW, Leurgans SE, Bennett DA, Schneider JA
The Lancet. Neurology 15 (9):934-43. PubMed PMID: 27312738
Published date: 2016 Jun 13
Genetic variants in Alzheimer disease - molecular and brain network approaches.
Gaiteri C, Mostafavi S, Honey CJ, De Jager PL, Bennett DA
Nature reviews. Neurology 12 (7):413-27. PubMed PMID: 27282653
Published date: 2016 Jun 10
Postmortem MRI: a novel window into the neurobiology of late life cognitive decline.
Dawe RJ, Yu L, Leurgans SE, Schneider JA, Buchman AS, Arfanakis K, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 27459937
Published date: 2016 Jun 6
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC
PLoS biology 14 (6):e1002472. PubMed PMID: 27254664
Published date: 2016 Jun
Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology.
Scheff SW, Ansari MA, Mufson EJ
Neurobiology of aging. PubMed PMID: 27143416
Published date: 2016 Jun
Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease.
Tiernan CT, Ginsberg SD, Guillozet-Bongaarts AL, Ward SM, He B, Kanaan NM, Mufson EJ, Binder LI, Counts SE
Neurobiology of aging. PubMed PMID: 27143424
Published date: 2016 Jun
Neuropathologic differences by race from the National Alzheimer's Coordinating Center.
Graff-Radford NR, Besser LM, Crook JE, Kukull WA, Dickson DW
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (6):669-77. PubMed PMID: 27094726
Published date: 2016 06
Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum.
Serrano-Pozo A, Qian J, Muzikansky A, Monsell SE, Montine TJ, Frosch MP, Betensky RA, Hyman BT
Journal of neuropathology and experimental neurology 75 (6):516-26. PubMed PMID: 27105663
Published date: 2016 06
Genome-wide association study identifies 74 loci associated with educational attainment.
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Con
Nature 533 (7604):539-42. PubMed PMID: 27225129
Published date: 2016 May 26
Measurement and control of bias in patient reported outcomes using multidimensional item response theory.
Dowling NM, Bolt DM, Deng S, Li C
BMC medical research methodology. PubMed PMID: 27229310
Published date: 2016 05 26
Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis.
Sajeev G, Weuve J, Jackson JW, VanderWeele TJ, Bennett DA, Grodstein F, Blacker D
Epidemiology (Cambridge, Mass.) 27 (5):732-42. PubMed PMID: 27227783
Published date: 2016 May 25
The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK
Neurobiology of aging. PubMed PMID: 27103524
Published date: 2016 May
Assessment of the genetic variance of late-onset Alzheimer's disease.
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK
Neurobiology of aging. PubMed PMID: 27036079
Published date: 2016 May
Motor Function Is Associated With Incident Disability in Older African Americans.
Buchman AS, Wilson RS, Yu L, Boyle PA, Bennett DA, Barnes LL
The journals of gerontology. Series A, Biological sciences and medical sciences 71 (5):696-702. PubMed PMID: 26525087
Published date: 2016 May
Sigmoidal mixed models for longitudinal data.
Capuano AW, Wilson RS, Leurgans SE, Dawson JD, Bennett DA, Hedeker D
Statistical methods in medical research 27 (3):863-875. PubMed PMID: 27130491
Published date: 2016 Apr 28
Temporal course of neurodegenerative effects on cognition in old age.
Wilson RS, Capuano AW, Bennett DA, Schneider JA, Boyle PA
Neuropsychology 30 (5):591-9. PubMed PMID: 27111293
Published date: 2016 Apr 25
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linne?r RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonza
Nature genetics 48 (6):624-33. PubMed PMID: 27089181
Published date: 2016 Apr 18
Occupational cognitive requirements and late-life cognitive aging.
Pool LR, Weuve J, Wilson RS, Bültmann U, Evans DA, Mendes de Leon CF
Neurology 86 (15):1386-1392. PubMed PMID: 26984944
Published date: 2016 04 12
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.
Allen GI, Amoroso N, Anghel C, Balagurusamy V, Bare CJ, Beaton D, Bellotti R, Bennett DA, Boehme K, Boutros PC, Caberlotto L, Caloian C, Campbell F, Neto EC, Chang YC, Chen B, Chen CY, Chien TY, Clark T, Das S, Davatzikos C, Deng J, Dillenberger D, Dobson
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (6):645-53. PubMed PMID: 27079753
Published date: 2016 Apr 11
Results From the NACC Uniform Data Set Neuropsychological Battery Crosswalk Study.
Monsell SE, Dodge HH, Zhou XH, Bu Y, Besser LM, Mock C, Hawes SE, Kukull WA, Weintraub S
Alzheimer disease and associated disorders 30 (2):134-9. PubMed PMID: 26485498
Published date: 2016 Apr-Jun
Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.
Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 36 (4):819-30. PubMed PMID: 26762507
Published date: 2016 Apr
Benzodiazepine Use and Cognitive Decline in Elderly With Normal Cognition.
Zhang Y, Zhou XH, Meranus DH, Wang L, Kukull WA
Alzheimer disease and associated disorders 30 (2):113-7. PubMed PMID: 26067923
Published date: 2016 Apr-Jun
Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.
Roostaei T, Nazeri A, Felsky D, De Jager PL, Schneider JA, Pollock BG, Bennett DA, Voineskos AN
Molecular psychiatry 22 (2):287-295. PubMed PMID: 27021820
Published date: 2016 Mar 29
Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.
Yu L, Chibnik L, Yang J, McCabe C, Xu J, Schneider JA, De Jager PL, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (9):942-51. PubMed PMID: 27016692
Published date: 2016 Mar 23
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.
Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, Wellmann J, Cornelis MC, Ollila HM, Yu L, Smith JA, Pilling LC, Isaacs A, Palotie A, Zhuang WV, Zonderman A, Faul JD, Sutin A, Meirelles O, Mulas A,
Psychological medicine 46 (8):1-11. PubMed PMID: 26997408
Published date: 2016 Mar 21
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T,
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (3):233-43. PubMed PMID: 26092349
Published date: 2016 Mar
Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
Karch CM, Ezerskiy LA, Bertelsen S, Goate AM
PloS one 11 (2):e0148717. PubMed PMID: 26919393
Published date: 2016
Independent and interactive impacts of hypertension and diabetes mellitus on verbal memory: A coordinated analysis of longitudinal data from England, Sweden, and the United States.
Kelly A, Calamia M, Koval A, Terrera GM, Piccinin AM, Clouston S, Hassing LB, Bennett DA, Johansson B, Hofer SM
Psychology and aging 31 (3):262-73. PubMed PMID: 26913926
Published date: 2016 Feb 25
Mini Mental State Examination and Logical Memory scores for entry into Alzheimer's disease trials.
Chapman KR, Bing-Canar H, Alosco ML, Steinberg EG, Martin B, Chaisson C, Kowall N, Tripodis Y, Stern RA
Alzheimer's research & therapy. PubMed PMID: 26899835
Published date: 2016 Feb 22
Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.
Hinrich AJ, Jodelka FM, Chang JL, Brutman D, Bruno AM, Briggs CA, James BD, Stutzmann GE, Bennett DA, Miller SA, Rigo F, Marr RA, Hastings ML
EMBO molecular medicine 8 (4):328-45. PubMed PMID: 26902204
Published date: 2016 Feb 22
Clinicopathological correlation of psychosis and brain vascular changes in Alzheimer's disease.
Ting SK, Hao Y, Chia PS, Tan EK, Hameed S
Scientific reports. PubMed PMID: 26868671
Published date: 2016 Feb 12
Assessing the genetic overlap between BMI and cognitive function.
Marioni RE, Yang J, Dykiert D, Mo?ttus R, Campbell A, Davies G, Hayward C, Porteous DJ, Visscher PM, Deary IJ
Molecular psychiatry 21 (10):1477-82. PubMed PMID: 26857597
Published date: 2016 Feb 9
The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts.
Arvanitakis Z, Capuano AW, Leurgans SE, Buchman AS, Bennett DA, Schneider JA
Brain pathology (Zurich, Switzerland) 27 (1):77-85. PubMed PMID: 26844934
Published date: 2016 Feb 4
Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, Haines JL, Thornton-Wells TA
Neurobiology of aging. PubMed PMID: 26827652
Published date: 2016 Feb
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman A?K, Haring R, Hysi PG, Iles MM, Justice AE, Kanoni S, Lagou V, Li R, Li X, Locke A, Lu C, Ma?gi R
Nature communications. PubMed PMID: 26833246
Published date: 2016 Feb 01
Association of Age at Menopause and Duration of Reproductive Period With Depression After Menopause: A Systematic Review and Meta-analysis.
Georgakis MK, Thomopoulos TP, Diamantaras AA, Kalogirou EI, Skalkidou A, Daskalopoulou SS, Petridou ET
JAMA psychiatry 73 (2):139-49. PubMed PMID: 26747373
Published date: 2016 Feb
Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.
Ebbert MTW, Boehme KL, Wadsworth ME, Staley LA, Mukherjee S, Crane PK, Ridge PG, Kauwe JSK
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (2):121-129. PubMed PMID: 26449541
Published date: 2016 Feb
Patterns of Neuropsychiatric Symptoms in Mild Cognitive Impairment and Risk of Dementia.
Forrester SN, Gallo JJ, Smith GS, Leoutsakos JM
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 24 (2):117-25. PubMed PMID: 26209222
Published date: 2016 Feb
Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease.
Counts SE, He B, Prout JG, Michalski B, Farotti L, Fahnestock M, Mufson EJ
Current Alzheimer research 13 (7):800-8. PubMed PMID: 26825093
Published date: 2016
Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA
Neurology 86 (8):735-41. PubMed PMID: 26819457
Published date: 2016 Jan 27
Olfactory Dysfunction in Older Adults is Associated with Feelings of Depression and Loneliness.
Sivam A, Wroblewski KE, Alkorta-Aranburu G, Barnes LL, Wilson RS, Bennett DA, Pinto JM
Chemical senses 41 (4):293-9. PubMed PMID: 26809485
Published date: 2016 Jan 24
Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.
Abner EL, Nelson PT, Kryscio RJ, Schmitt FA, Fardo DW, Woltjer RL, Cairns NJ, Yu L, Dodge HH, Xiong C, Masaki K, Tyas SL, Bennett DA, Schneider JA, Arvanitakis Z
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (8):882-9. PubMed PMID: 26812281
Published date: 2016 Jan 23
Cardiorespiratory fitness and cognition in the elderly: Can you outrun cognitive impairment?
Roever L, Bennett DA
Neurology 86 (5):408-9. PubMed PMID: 26740672
Published date: 2016 Jan 6
Self-Reported Traumatic Brain Injury and Mild Cognitive Impairment: Increased Risk and Earlier Age of Diagnosis.
LoBue C, Denney D, Hynan LS, Rossetti HC, Lacritz LH, Hart J, Womack KB, Woon FL, Cullum CM
Journal of Alzheimer's disease : JAD 51 (3):727-36. PubMed PMID: 26890760
Published date: 2016
Evaluation of Cerebrospinal Fluid Assay Variability in Alzheimer's Disease.
White MT, Shaw LM, Xie SX
Journal of Alzheimer's disease : JAD 51 (2):463-70. PubMed PMID: 26890778
Published date: 2016
Progression of Extrapyramidal Signs in Alzheimer's Disease: Clinical and Neuropathological Correlates.
Tosto G, Monsell SE, Hawes SE, Bruno G, Mayeux R
Journal of Alzheimer's disease : JAD 49 (4):1085-93. PubMed PMID: 26599050
Published date: 2016
Lewy Bodies, Vascular Risk Factors, and Subcortical Arteriosclerotic Leukoencephalopathy, but not Alzheimer Pathology, are Associated with Development of Psychosis in Alzheimer's Disease.
Fischer CE, Qian W, Schweizer TA, Millikin CP, Ismail Z, Smith EE, Lix LM, Shelton P, Munoz DG
Journal of Alzheimer's disease : JAD 50 (1):283-95. PubMed PMID: 26682680
Published date: 2016
Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment.
Mufson EJ, Malek-Ahmadi M, Perez SE, Chen K
Neurobiology of aging. PubMed PMID: 26686670
Published date: 2016 Jan
Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease.
Beck JS, Mufson EJ, Counts SE
Current Alzheimer research 13 (6):610-4. PubMed PMID: 26687188
Published date: 2016
Sex-specific patterns and differences in dementia and Alzheimer's disease using informatics approaches.
Ronquillo JG, Baer MR, Lester WT
Journal of women & aging 28 (5):403-11. PubMed PMID: 27105335
Published date: 2016
Impact of Alzheimer's Disease, Lewy Body and Vascular Co-Pathologies on Clinical Transition to Dementia in a National Autopsy Cohort.
Pillai JA, Butler RS, Bonner-Jackson A, Leverenz JB
Dementia and geriatric cognitive disorders 42 (1-2):106-16. PubMed PMID: 27623397
Published date: 2016
A MULTIVARIATE FINITE MIXTURE LATENT TRAJECTORY MODEL WITH APPLICATION TO DEMENTIA STUDIES.
Lai D, Xu H, Koller D, Foroud T, Gao S
Journal of applied statistics 43 (14):2503-2523. PubMed PMID: 27642206
Published date: 2016
Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.
Levine ME, Lu AT, Bennett DA, Horvath S
Aging 7 (12):1198-211. PubMed PMID: 26684672
Published date: 2015 Dec 18
Identifying the Association Between Alzheimer's Disease and Parkinson's Disease Using Genome-Wide Association Studies and Protein-Protein Interaction Network.
Liu G, Bao X, Jiang Y, Liao M, Jiang Q, Feng R, Zhang L, Ma G, Chen Z, Wang G, Wang R, Zhao B, Li K
Molecular neurobiology 52 (3):1629-1636. PubMed PMID: 25370933
Published date: 2015 Dec
Hippocampal plasticity during the progression of Alzheimer's disease.
Mufson EJ, Mahady L, Waters D, Counts SE, Perez SE, DeKosky ST, Ginsberg SD, Ikonomovic MD, Scheff SW, Binder LI
Neuroscience. PubMed PMID: 25772787
Published date: 2015 Nov 19
Antihypertensive and Statin Medication Use and Motor Function in Community-Dwelling Older Adults.
Perlman A, Shah RC, Bennett DA, Buchman AS, Matok I
Journal of the American Medical Directors Association 17 (3):220-224. PubMed PMID: 26597419
Published date: 2015 Nov 17
Examination of the Factor Structure of a Global Cognitive Function Battery across Race and Time.
Barnes LL, Yumoto F, Capuano A, Wilson RS, Bennett DA, Tractenberg RE
Journal of the International Neuropsychological Society : JINS 22 (1):1-10. PubMed PMID: 26563713
Published date: 2015 Nov 13
Change in Cognitive Abilities in Older Latinos.
Wilson RS, Capuano AW, Marquez DX, Amofa P, Barnes LL, Bennett DA
Journal of the International Neuropsychological Society : JINS 22 (1):1-8. PubMed PMID: 26553103
Published date: 2015 Nov 10
Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment.
Weinberg RB, Mufson EJ, Counts SE
Frontiers in neuroscience. PubMed PMID: 26594146
Published date: 2015
Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons.
Boyle PA, Yu L, Nag S, Leurgans S, Wilson RS, Bennett DA, Schneider JA
Neurology 85 (22):1930-6. PubMed PMID: 26537052
Published date: 2015 Nov 4
Neuropsychological Markers of Cognitive Decline in Persons With Alzheimer Disease Neuropathology.
Hassenstab J, Monsell SE, Mock C, Roe CM, Cairns NJ, Morris JC, Kukull W
Journal of neuropathology and experimental neurology 74 (11):1086-92. PubMed PMID: 26469250
Published date: 2015 Nov
Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.
Dong J, Yang J, Tranah G, Franceschini N, Parimi N, Alkorta-Aranburu G, Xu Z, Alonso A, Cummings SR, Fornage M, Huang X, Kritchevsky S, Liu Y, London S, Niu L, Wilson RS, De Jager PL, Yu L, Singleton AB, Harris T, Mosley TH, Pinto JM, Bennett DA, Chen H
Medicine 94 (47):e1892. PubMed PMID: 26632684
Published date: 2015 Nov
Pattern of extrapyramidal signs in Alzheimer's disease.
Tosto G, Monsell SE, Hawes SE, Mayeux R
Journal of neurology 262 (11):2548-56. PubMed PMID: 26338814
Published date: 2015 Nov
Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons.
Neuman KM, Molina-Campos E, Musial TF, Price AL, Oh KJ, Wolke ML, Buss EW, Scheff SW, Mufson EJ, Nicholson DA
Brain structure & function 220 (6):3143-65. PubMed PMID: 25031178
Published date: 2015 Nov
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Dickson DW, Rademakers R, Nicholson AM, Schneider JA, Yu L, Bennett DA
Neurology 85 (15):1354-5. PubMed PMID: 26459943
Published date: 2015 Oct 13
Common variants in DRD2 are associated with sleep duration: the CARe consortium.
Cade BE, Gottlieb DJ, Lauderdale DS, Bennett DA, Buchman AS, Buxbaum SG, De Jager PL, Evans DS, Fu?lo?p T, Gharib SA, Johnson WC, Kim H, Larkin EK, Lee SK, Lim AS, Punjabi NM, Shin C, Stone KL, Tranah GJ, Weng J, Yaffe K, Zee PC, Patel SR, Zhu X, Red
Human molecular genetics 25 (1):167-79. PubMed PMID: 26464489
Published date: 2015 Oct 13
Author Response.
Schneider JA, Yu L, Bennett DA
Neurology 85 (15):1355. PubMed PMID: 26744756
Published date: 2015 Oct 13
Parsing the heterogeneity of mild cognitive impairment: Lumpers and splitters.
Burns JM, Bennett DA
Neurology 85 (19):1646-7. PubMed PMID: 26453644
Published date: 2015 Oct 9
Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers.
Lugli G, Cohen AM, Bennett DA, Shah RC, Fields CJ, Hernandez AG, Smalheiser NR
PloS one 10 (10):e0139233. PubMed PMID: 26426747
Published date: 2015
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpela?inen TO, Lu Y, Ma?gi R, Mihailov E, Pers TH, Ru?eger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD,
PLoS genetics 11 (10):e1005378. PubMed PMID: 26426971
Published date: 2015 Oct
Cerebral amyloid angiopathy and its co-occurrence with Alzheimer's disease and other cerebrovascular neuropathologic changes.
Brenowitz WD, Nelson PT, Besser LM, Heller KB, Kukull WA
Neurobiology of aging 36 (10):2702-8. PubMed PMID: 26239176
Published date: 2015 Oct
Characterizing Apolipoprotein E 4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal -Amyloid Peptide Plaques.
Monsell SE, Kukull WA, Roher AE, Maarouf CL, Serrano G, Beach TG, Caselli RJ, Montine TJ, Reiman EM
JAMA neurology 72 (10):1124-31. PubMed PMID: 26302353
Published date: 2015 Oct
Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database.
Torralva T, Sposato LA, Riccio PM, Gleichgerrcht E, Roca M, Toledo JB, Trojanowski JQ, Kukull WA, Manes F, Hachinski V
Neurobiology of aging 36 (10):2861-8. PubMed PMID: 26220367
Published date: 2015 Oct
Alzheimer's disease: Unique markers for diagnosis & new treatment modalities.
Aggarwal NT, Shah RC, Bennett DA
The Indian journal of medical research 142 (4):369-82. PubMed PMID: 26609028
Published date: 2015 Oct
Association of APOE with tau-tangle pathology with and without β-amyloid.
Farfel JM, Yu L, De Jager PL, Schneider JA, Bennett DA
Neurobiology of aging. PubMed PMID: 26481403
Published date: 2015 Sep 28
CD33 modulates TREM2: convergence of Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL
Nature neuroscience 18 (11):1556-8. PubMed PMID: 26414614
Published date: 2015 Sep 28
Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.
Zhang J, Wang S, Huang W, Bennett DA, Dickson DW, Wang D, Wang R
Molecular neurobiology 53 (8):5066-78. PubMed PMID: 26386840
Published date: 2015 Sep 19
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC
JAMA neurology 72 (11):1313-23. PubMed PMID: 26366463
Published date: 2015 Sep 14
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Smith PY, Hernandez-Rapp J, Jolivette F, Lecours C, Bisht K, Goupil C, Dorval V, Parsi S, Morin F, Planel E, Bennett DA, Fernandez-Gomez FJ, Sergeant N, Bue?e L, Tremblay ME?, Calon F, He?bert SS
Human molecular genetics 24 (23):6721-35. PubMed PMID: 26362250
Published date: 2015 Sep 11
Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology.
Buchman AS, Wilson RS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 71 (4):549-56. PubMed PMID: 26362440
Published date: 2015 Sep 10
Guidelines for reporting methodological challenges and evaluating potential bias in dementia research.
Weuve J, Proust-Lima C, Power MC, Gross AL, Hofer SM, Thibaut R, Chne G, Glymour MM, Dufouil C
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (9):1098-109. PubMed PMID: 26397878
Published date: 2015 Sep
Stroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes.
Hohman TJ, Samuels LR, Liu D, Gifford KA, Mukherjee S, Benson EM, Abel T, Ruberg FL, Jefferson AL
Neurobiology of aging 36 (9):2501-8. PubMed PMID: 26119224
Published date: 2015 Sep
Quantile regression with a change-point model for longitudinal data: An application to the study of cognitive changes in preclinical alzheimer's disease.
Li C, Dowling NM, Chappell R
Biometrics 71 (3):625-35. PubMed PMID: 25892034
Published date: 2015 Sep
Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease.
Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BT
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (2):164-9. PubMed PMID: 26327235
Published date: 2015 Aug 29
Temporal course and pathologic basis of unawareness of memory loss in dementia.
Wilson RS, Boyle PA, Yu L, Barnes LL, Sytsma J, Buchman AS, Bennett DA, Schneider JA
Neurology 85 (11):984-91. PubMed PMID: 26311746
Published date: 2015 Aug 26
APOE and cerebral amyloid angiopathy in community-dwelling older persons.
Yu L, Boyle PA, Nag S, Leurgans S, Buchman AS, Wilson RS, Arvanitakis Z, Farfel JM, De Jager PL, Bennett DA, Schneider JA
Neurobiology of aging 36 (11):2946-53. PubMed PMID: 26341746
Published date: 2015 Aug 15
Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families.
Barral S, Vardarajan BN, Faber KM, Bird TD, Tsuang D, Bennett DA, Rosenberg R, Boeve BF, Graff-Radford NR, Goate AM, Farlow M, Lantigua R, Medrano MZ, Wang X, Kamboh MI, Barmada MM, Schaid DJ, Foroud TM, Weamer EA, Ottman R, Sweet RA, Mayeux R
Neurobiology of aging 36 (11):3116.e9-3116.e16. PubMed PMID: 26359528
Published date: 2015 Aug 15
GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.
Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, McDonald BC, Yoder KK, Hutchins GD, West JD, Tallman EF, Gao S, Foroud TM, Farlow MR, De Jager PL, Bennett DA, Aisen PS, Petersen RC, Jack CR, Toga AW, Green RC, Jagust WJ, Weiner MW, Saykin AJ
Brain : a journal of neurology 138 (Pt 10):3076-3088. PubMed PMID: 26268530
Published date: 2015 Aug 11
Late-life depression is not associated with dementia-related pathology.
Wilson RS, Boyle PA, Capuano AW, Shah RC, Hoganson GM, Nag S, Bennett DA
Neuropsychology 30 (2):135-42. PubMed PMID: 26237627
Published date: 2015 Aug 3
Motoric cognitive risk syndrome: multicenter incidence study.
Mahlknecht P, Kiechl S, Willeit J, Poewe W, Seppi K, Verghese J, Kowal P, Bennett DA
Neurology 85 (4):388-9. PubMed PMID: 26215881
Published date: 2015 Jul 28
Author response.
Verghese J, Kowal P, Bennett DA
Neurology 85 (4):389. PubMed PMID: 26436154
Published date: 2015 Jul 28
Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease.
Rangasamy SB, Corbett GT, Roy A, Modi KK, Bennett DA, Mufson EJ, Ghosh S, Pahan K
Journal of Alzheimer's disease : JAD 47 (2):385-402. PubMed PMID: 26401561
Published date: 2015 Jul 24
Change in motor function and adverse health outcomes in older African-Americans.
Buchman AS, Wilson RS, Leurgans SE, Bennett DA, Barnes LL
Experimental gerontology. PubMed PMID: 26209439
Published date: 2015 Jul 21
GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.
Hohman TJ, Chibnik L, Bush WS, Jefferson AL, De Jaeger PL, Thornton-Wells TA, Bennett DA, Schneider JA
Neurotoxicity research 28 (3):232-8. PubMed PMID: 26194614
Published date: 2015 Jul 21
Mixed pathology is more likely in black than white decedents with Alzheimer dementia.
Barnes LL, Leurgans S, Aggarwal NT, Shah RC, Arvanitakis Z, James BD, Buchman AS, Bennett DA, Schneider JA
Neurology 85 (6):528-34. PubMed PMID: 26180136
Published date: 2015 Jul 15
Clinical Features of Alzheimer Disease With and Without Lewy Bodies.
Chung EJ, Babulal GM, Monsell SE, Cairns NJ, Roe CM, Morris JC
JAMA neurology 72 (7):789-96. PubMed PMID: 25985321
Published date: 2015 Jul
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV
Nature neuroscience 18 (7):978-87. PubMed PMID: 26005850
Published date: 2015 Jul
Neuropathologic correlates of regional brain volumes in a community cohort of older adults.
Kotrotsou A, Schneider JA, Bennett DA, Leurgans SE, Dawe RJ, Boyle PA, Golak T, Arfanakis K
Neurobiology of aging 36 (10):2798-805. PubMed PMID: 26195068
Published date: 2015 Jun 30
Reply to Itzhaki.
Barnes LL, Capuano AW, Aiello AE, Turner AD, Yolken RH, Torrey EF, Bennett DA
The Journal of infectious diseases 211 (12):2024. PubMed PMID: 25635124
Published date: 2015 Jun 15
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Mukherjee S, Walter S, Kauwe JS, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (12):1439-51. PubMed PMID: 26079416
Published date: 2015 Jun 12
Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
stergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA
PLoS medicine 12 (6):e1001841; discussion. PubMed PMID: 26079503
Published date: 2015 Jun
Alzheimer's loci: epigenetic associations and interaction with genetic factors.
Chibnik LB, Yu L, Eaton ML, Srivastava G, Schneider JA, Kellis M, Bennett DA, De Jager PL
Annals of clinical and translational neurology 2 (6):636-47. PubMed PMID: 26125039
Published date: 2015 Jun
Vascular contributions to cognitive impairment and dementia including Alzheimer's disease.
Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (6):710-7. PubMed PMID: 25510382
Published date: 2015 Jun
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
Yang J, Yu L, Gaiteri C, Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA
The international journal of biochemistry & cell biology. PubMed PMID: 26003740
Published date: 2015 May 20
Cognitive activity, cognitive function, and brain diffusion characteristics in old age.
Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, Fleischman DA, Bennett DA
Brain imaging and behavior 10 (2):455-63. PubMed PMID: 25982658
Published date: 2015 May 16
Cognitive aging in older Black and White persons.
Wilson RS, Capuano AW, Sytsma J, Bennett DA, Barnes LL
Psychology and aging 30 (2):279-85. PubMed PMID: 25961876
Published date: 2015 May 11
PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.
Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, Montine TJ, Nelson PT, Schmitt F, Schneider JA, Serrano-Pozo A, Thal DR, Toledo JB, T
Acta neuropathologica 129 (5):757-62. PubMed PMID: 25778618
Published date: 2015 May
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J, Willems
Molecular psychiatry 20 (6):735-43. PubMed PMID: 25917368
Published date: 2015 Apr 28
Effect of common neuropathologies on progression of late life cognitive impairment.
Yu L, Boyle PA, Leurgans S, Schneider JA, Kryscio RJ, Wilson RS, Bennett DA
Neurobiology of aging 36 (7):2225-31. PubMed PMID: 25976345
Published date: 2015 Apr 22
α-Synuclein pathology accumulates in sacral spinal visceral sensory pathways.
VanderHorst VG, Samardzic T, Saper CB, Anderson MP, Nag S, Schneider JA, Bennett DA, Buchman AS
Annals of neurology 78 (1):142-9. PubMed PMID: 25893830
Published date: 2015 Apr 20
Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.
Perez SE, He B, Nadeem M, Wuu J, Scheff SW, Abrahamson EE, Ikonomovic MD, Mufson EJ
Biological psychiatry 77 (8):693-703. PubMed PMID: 24529280
Published date: 2015 Apr 15
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Sch
Molecular psychiatry 21 (2):189-97. PubMed PMID: 25869804
Published date: 2015 Apr 14
Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology.
Perez SE, He B, Nadeem M, Wuu J, Ginsberg SD, Ikonomovic MD, Mufson EJ
Journal of neuropathology and experimental neurology 74 (4):345-58. PubMed PMID: 25756588
Published date: 2015 Apr
Dementia: Cognitive resilience in APOE*ε4 carriers—is race important?
Barnes LL, Bennett DA
Nature reviews. Neurology 11 (4):190-1. PubMed PMID: 25799927
Published date: 2015 Apr
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, To?glhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikan
Neurobiology of aging 36 (4):1765.e7-16. PubMed PMID: 25670335
Published date: 2015 Apr
PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease.
Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, Frosch MP, Ghetti B, Foroud TM, Honig LS, Marder K, Vonsattel JP, Gol
Neurology 84 (10):972-80. PubMed PMID: 25663231
Published date: 2015 Mar 10
Conscientiousness, dementia related pathology, and trajectories of cognitive aging.
Wilson RS, Boyle PA, Yu L, Segawa E, Sytsma J, Bennett DA
Psychology and aging 30 (1):74-82. PubMed PMID: 25664558
Published date: 2015 Mar
The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia.
Abner EL, Schmitt FA, Nelson PT, Lou W, Wan L, Gauriglia R, Dodge HH, Woltjer RL, Yu L, Bennet DA, Schneider JA, Chen R, Masaki K, Katz MJ, Lipton RB, Dickson DW, Lim KO, Hemmy LS, Cairns NJ, Grant E, Tyas SL, Xiong C, Fardo DW, Kryscio RJ
Observational studies 1 (2015):56-73. PubMed PMID: 25984574
Published date: 2015 Mar
Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease.
Nag S, Yu L, Capuano AW, Wilson RS, Leurgans SE, Bennett DA, Schneider JA
Annals of neurology 77 (6):942-52. PubMed PMID: 25707479
Published date: 2015 Feb 23
Integrative analysis of 111 reference human epigenomes.
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coar
Nature 518 (7539):317-30. PubMed PMID: 25693563
Published date: 2015 Feb 19
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Yu L, De Jager PL, Yang J, Trojanowski JQ, Bennett DA, Schneider JA
Neurology 84 (9):927-34. PubMed PMID: 25653292
Published date: 2015 Feb 4
B-lymphocyte-mediated delayed cognitive impairment following stroke.
Doyle KP, Quach LN, Sole? M, Axtell RC, Nguyen TV, Soler-Llavina GJ, Jurado S, Han J, Steinman L, Longo FM, Schneider JA, Malenka RC, Buckwalter MS
The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (5):2133-45. PubMed PMID: 25653369
Published date: 2015 Feb 04
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, Postmus I, Smith AV, Smith JA, Thalamuthu A, Thomson R, Vitart V, Wang J,
Molecular psychiatry 20 (2):183-92. PubMed PMID: 25644384
Published date: 2015 Feb 3
From Neurodegeneration to Brain Health: An Integrated Approach.
Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz WK, Wang Y, Whitehouse P, Lerner A
Journal of Alzheimer's disease : JAD 46 (1):271-83. PubMed PMID: 25720413
Published date: 2015
Irregular 24-hour activity rhythms and the metabolic syndrome in older adults.
Sohail S, Yu L, Bennett DA, Buchman AS, Lim AS
Chronobiology international 32 (6):802-13. PubMed PMID: 26061588
Published date: 2015
Relationship between Auditory and Cognitive Abilities in Older Adults.
Sheft S, Shafiro V, Wang E, Barnes LL, Shah RC
PloS one 10 (8):e0134330. PubMed PMID: 26237423
Published date: 2015
Prevalence of Traumatic Brain Injury in Early Versus Late-Onset Alzheimer's Disease.
Mendez MF, Paholpak P, Lin A, Zhang JY, Teng E
Journal of Alzheimer's disease : JAD 47 (4):985-93. PubMed PMID: 26401777
Published date: 2015
Latent Classes of Neuropsychiatric Symptoms in NACC Controls and Conversion to Mild Cognitive Impairment or Dementia.
Leoutsakos JM, Forrester SN, Lyketsos CG, Smith GS
Journal of Alzheimer's disease : JAD 48 (2):483-93. PubMed PMID: 26402012
Published date: 2015
Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease.
Pivtoraiko VN, Abrahamson EE, Leurgans SE, DeKosky ST, Mufson EJ, Ikonomovic MD
Neurobiology of aging 36 (1):12-9. PubMed PMID: 25048160
Published date: 2015 Jan
Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease.
Scheff SW, Price DA, Ansari MA, Roberts KN, Schmitt FA, Ikonomovic MD, Mufson EJ
Journal of Alzheimer's disease : JAD 43 (3):1073-90. PubMed PMID: 25147118
Published date: 2015
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA
The journals of gerontology. Series A, Biological sciences and medical sciences 70 (1):110-8. PubMed PMID: 25199915
Published date: 2015 Jan
Antipsychotic Use in a Diverse Population With Dementia: A Retrospective Review of the National Alzheimer's Coordinating Center Database.
Xiong GL, Filshtein T, Beckett LA, Hinton L
The Journal of neuropsychiatry and clinical neurosciences 27 (4):326-32. PubMed PMID: 26488486
Published date: 2015 Fall
Genetic diversity is a predictor of mortality in humans.
Bihlmeyer NA, Brody JA, Smith A, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza S, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M,
BMC genetics 15 (1):1274. PubMed PMID: 25543667
Published date: 2014 Dec 29
A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.
Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL
Annals of neurology 77 (3):469-77. PubMed PMID: 25545807
Published date: 2014 Dec 26
Residual decline in cognition after adjustment for common neuropathologic conditions.
Yu L, Boyle PA, Segawa E, Leurgans S, Schneider JA, Wilson RS, Bennett DA
Neuropsychology 29 (3):335-43. PubMed PMID: 25495832
Published date: 2014 Dec 15
Motoric cognitive risk syndrome: Multicenter incidence study.
Verghese J, Ayers E, Barzilai N, Bennett DA, Buchman AS, Holtzer R, Katz MJ, Lipton RB, Wang C
Neurology 83 (24):2278-84. PubMed PMID: 25361778
Published date: 2014 Dec 09
Primary age-related tauopathy (PART): a common pathology associated with human aging.
Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA
Acta neuropathologica 128 (6):755-66. PubMed PMID: 25348064
Published date: 2014 Dec
Brain pathology contributes to simultaneous change in physical frailty and cognition in old age.
Buchman AS, Yu L, Wilson RS, Boyle PA, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 69 (12):1536-44. PubMed PMID: 25136002
Published date: 2014 Dec
Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell
Biological psychiatry 77 (8):749-63. PubMed PMID: 25648963
Published date: 2014 Nov 25
Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets.
Gross AL, Sherva R, Mukherjee S, Newhouse S, Kauwe JS, Munsie LM, Waterston LB, Bennett DA, Jones RN, Green RC, Crane PK
Neuroepidemiology 43 (3-4):194-205. PubMed PMID: 25402421
Published date: 2014 Nov 13
FASTKD2 is associated with memory and hippocampal structure in older adults.
Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Aisen PS, Petersen RC, Jack CR, Shaw LM, Trojanowski JQ, Weiner MW, Green RC, Toga AW, De
Molecular psychiatry 20 (10):1197-204. PubMed PMID: 25385369
Published date: 2014 Nov 11
Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.
Yu L, Chibnik LB, Srivastava GP, Pochet N, Yang J, Xu J, Kozubek J, Obholzer N, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA
JAMA neurology 72 (1):15-24. PubMed PMID: 25365775
Published date: 2014 Nov 3
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.
Lim AS, Srivastava GP, Yu L, Chibnik LB, Xu J, Buchman AS, Schneider JA, Myers AJ, Bennett DA, De Jager PL
PLoS genetics 10 (11):e1004792. PubMed PMID: 25375876
Published date: 2014 Nov
Relation of antiphospholipid antibodies to postmortem brain infarcts in older people.
Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Capuano AW, Yu L, Leurgans SE, Bennett DA, Levine SR
Circulation 131 (2):182-9. PubMed PMID: 25301832
Published date: 2014 Oct 9
Theoretical impact of Florbetapir (18F) amyloid imaging on diagnosis of alzheimer dementia and detection of preclinical cortical amyloid.
Beach TG, Schneider JA, Sue LI, Serrano G, Dugger BN, Monsell SE, Kukull W
Journal of neuropathology and experimental neurology 73 (10):948-53. PubMed PMID: 25192053
Published date: 2014 Oct
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer
JAMA neurology 71 (11):1394-404. PubMed PMID: 25199842
Published date: 2014 Sep 8
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P
PLoS genetics 10 (9):e1004606. PubMed PMID: 25188341
Published date: 2014 Sep
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA
Annals of neurology 76 (3):379-92. PubMed PMID: 25043464
Published date: 2014 Sep
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T, Goate A, Graff-Radford NR, Kamboh MI, Kukull WA, Manly JJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (6):609-618.e11. PubMed PMID: 25172201
Published date: 2014 Aug 26
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissn
Nature neuroscience 17 (9):1156-63. PubMed PMID: 25129075
Published date: 2014 Aug 17
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J
Nature neuroscience 17 (9):1164-70. PubMed PMID: 25129077
Published date: 2014 Aug 17
Cytomegalovirus infection and risk of Alzheimer disease in older black and white individuals.
Barnes LL, Capuano AW, Aiello AE, Turner AD, Yolken RH, Torrey EF, Bennett DA
The Journal of infectious diseases 211 (2):230-7. PubMed PMID: 25108028
Published date: 2014 Aug 8
Parahippocampal white matter volume predicts Alzheimer's disease risk in cognitively normal old adults.
Stoub TR, Detoledo-Morrell L, Dickerson BC
Neurobiology of aging 35 (8):1855-61. PubMed PMID: 24656833
Published date: 2014 Aug
Clinical-pathologic study of depressive symptoms and cognitive decline in old age.
Wilson RS, Capuano AW, Boyle PA, Hoganson GM, Hizel LP, Shah RC, Nag S, Schneider JA, Arnold SE, Bennett DA
Neurology 83 (8):702-9. PubMed PMID: 25080520
Published date: 2014 Jul 30
Motoric cognitive risk syndrome: multicountry prevalence and dementia risk.
Verghese J, Annweiler C, Ayers E, Barzilai N, Beauchet O, Bennett DA, Bridenbaugh SA, Buchman AS, Callisaya ML, Camicioli R, Capistrant B, Chatterji S, De Cock AM, Ferrucci L, Giladi N, Guralnik JM, Hausdorff JM, Holtzer R, Kim KW, Kowal P, Kressig R
Neurology 83 (8):718-26. PubMed PMID: 25031288
Published date: 2014 Jul 16
At the interface of sensory and motor dysfunctions and Alzheimer's disease.
Albers MW, Gilmore GC, Kaye J, Murphy C, Wingfield A, Bennett DA, Boxer AL, Buchman AS, Cruickshanks KJ, Devanand DP, Duffy CJ, Gall CM, Gates GA, Granholm AC, Hensch T, Holtzer R, Hyman BT, Lin FR, McKee AC, Morris JC, Petersen RC, Silbert LC, Strub
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (1):70-98. PubMed PMID: 25022540
Published date: 2014 Jul 8
Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions.
Serrano GE, Sabbagh MN, Sue LI, Hidalgo JA, Schneider JA, Bedell BJ, Van Deerlin VM, Suh E, Akiyama H, Joshi AD, Pontecorvo MJ, Mintun MA, Beach TG
Journal of Alzheimer's disease : JAD 42 (3):813-21. PubMed PMID: 24927705
Published date: 2014 Jun 13
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, D
PloS one 9 (6):e94661. PubMed PMID: 24922517
Published date: 2014
Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise? - authors' reply.
Greenberg SM, Al-Shahi Salman R, Biessels GJ, van Buchem M, Cordonnier C, Lee JM, Montaner J, Schneider JA, Smith EE, Vernooij M, Werring DJ
The Lancet. Neurology 13 (6):540. PubMed PMID: 24849857
Published date: 2014 Jun
Missense variant in TREML2 protects against Alzheimer's disease.
Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux
Neurobiology of aging 35 (6):1510.e19-26. PubMed PMID: 24439484
Published date: 2014 Jun
Epigenomics of Alzheimer's disease.
Bennett DA, Yu L, Yang J, Srivastava GP, Aubin C, De Jager PL
Translational research : the journal of laboratory and clinical medicine 165 (1):200-220. PubMed PMID: 24905038
Published date: 2014 May 16
Life extension factor klotho enhances cognition.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-O M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL, Mucke L
Cell reports 7 (4):1065-76. PubMed PMID: 24813892
Published date: 2014 May 7
Fragile X gene expansions are not associated with dementia.
Hall DA, Bennett DA, Filley CM, Shah RC, Kluger B, Ouyang B, Berry-Kravis E
Neurobiology of aging 35 (11):2637-2638. PubMed PMID: 24958193
Published date: 2014 May 2
A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases.
Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH
Journal of neuropathology and experimental neurology 73 (5):467-73. PubMed PMID: 24709683
Published date: 2014 May
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, Kawas CH, Cribbs DH, Bennett DA, Schneider JA, Larson EB, Crane PK, Valladares O, Schmitt
Acta neuropathologica 127 (6):825-43. PubMed PMID: 24770881
Published date: 2014 Apr 27
An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease.
Langbaum JB, Hendrix SB, Ayutyanont N, Chen K, Fleisher AS, Shah RC, Barnes LL, Bennett DA, Tariot PN, Reiman EM
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (6):666-74. PubMed PMID: 24751827
Published date: 2014 Apr 18
Alzheimer's disease in African Americans: risk factors and challenges for the future.
Barnes LL, Bennett DA
Health affairs (Project Hope) 33 (4):580-6. PubMed PMID: 24711318
Published date: 2014 Apr
Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits.
Ohta Y, Tremblay C, Schneider JA, Bennett DA, Calon F, Julien JP
Acta neuropathologica communications 2 (1):37. PubMed PMID: 24690380
Published date: 2014 Apr 1
Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.
Counts SE, Alldred MJ, Che S, Ginsberg SD, Mufson EJ
Neuropharmacology. PubMed PMID: 24445080
Published date: 2014 Apr
Outcome markers for clinical trials in cerebral amyloid angiopathy.
Greenberg SM, Al-Shahi Salman R, Biessels GJ, van Buchem M, Cordonnier C, Lee JM, Montaner J, Schneider JA, Smith EE, Vernooij M, Werring DJ
The Lancet. Neurology 13 (4):419-28. PubMed PMID: 24581702
Published date: 2014 Apr
Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
Shulman JM, Yu L, Buchman AS, Evans DA, Schneider JA, Bennett DA, De Jager PL
JAMA neurology 71 (4):429-35. PubMed PMID: 24514572
Published date: 2014 Apr
REST and stress resistance in ageing and Alzheimer's disease.
Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA
Nature 507 (7493):448-54. PubMed PMID: 24670762
Published date: 2014 Mar 27
Advances in the prevention of Alzheimer's disease and dementia.
Solomon A, Mangialasche F, Richard E, Andrieu S, Bennett DA, Breteler M, Fratiglioni L, Hooshmand B, Khachaturian AS, Schneider LS, Skoog I, Kivipelto M
Journal of internal medicine 275 (3):229-50. PubMed PMID: 24605807
Published date: 2014 Mar
Contribution of Alzheimer disease to mortality in the United States.
James BD, Leurgans SE, Hebert LE, Scherr PA, Yaffe K, Bennett DA
Neurology 82 (12):1045-50. PubMed PMID: 24598707
Published date: 2014 Mar 5
Ex vivo T2 relaxation: associations with age-related neuropathology and cognition.
Dawe RJ, Bennett DA, Schneider JA, Leurgans SE, Kotrotsou A, Boyle PA, Arfanakis K
Neurobiology of aging 35 (7):1549-61. PubMed PMID: 24582637
Published date: 2014 Feb 6
Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.
Bennett DA, Yu L, De Jager PL
Biochemical pharmacology 88 (4):617-630. PubMed PMID: 24508835
Published date: 2014 Feb 6
The nature, significance, and glucagon-like peptide-1 analog treatment of brain insulin resistance in Alzheimer's disease.
Talbot K, Wang HY
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (1 Suppl):S12-25. PubMed PMID: 24529520
Published date: 2014 Feb
Gene-behavior interaction of depressive symptoms and the apolipoprotein E {varepsilon}4 allele on cognitive decline.
Rajan KB, Wilson RS, Skarupski KA, Mendes de Leon CF, Evans DA
Psychosomatic medicine 76 (2):101-8. PubMed PMID: 24434953
Published date: 2014 Feb
Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues.
Song W, Zukor H, Liberman A, Kaduri S, Arvanitakis Z, Bennett DA, Schipper HM
Experimental neurology 254C (10):78-89. PubMed PMID: 24440642
Published date: 2014 Jan 15
Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment.
Leblanc AC, Ramcharitar J, Afonso V, Hamel E, Bennett DA, Pakavathkumar P, Albrecht S
Cell death and differentiation 21 (5):696-706. PubMed PMID: 24413155
Published date: 2014 Jan 10
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.
Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH
Journal of the American Chemical Society 136 (1):299-310. PubMed PMID: 24397771
Published date: 2014 Jan 8
Correlation between visual acuity and cognitive functions.
Elyashiv SM, Shabtai EL, Belkin M
The British journal of ophthalmology 98 (1):129-32. PubMed PMID: 24169658
Published date: 2014 Jan
Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates.
Dugger BN, Clark CM, Serrano G, Mariner M, Bedell BJ, Coleman RE, Doraiswamy PM, Lu M, Fleisher AS, Reiman EM, Sabbagh MN, Sadowsky CH, Schneider JA, Zehntner SP, Carpenter AP, Joshi AD, Mintun MA, Pontecorvo MJ, Skovronsky DM, Sue LI, Beach TG
Journal of neuropathology and experimental neurology 73 (1):72-80. PubMed PMID: 24335535
Published date: 2014 Jan
Prevalence of mixed pathologies in the aging brain.
Rahimi J, Kovacs GG
Alzheimer's research & therapy 6 (9):82. PubMed PMID: 25419243
Published date: 2014
Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
Kelley CM, Powers BE, Velazquez R, Ash JA, Ginsberg SD, Strupp BJ, Mufson EJ
Brain pathology (Zurich, Switzerland) 24 (1):33-44. PubMed PMID: 23802663
Published date: 2014 Jan
Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease.
Mufson EJ, Ward S, Binder L
Neuro-degenerative diseases 13 (2-3):151-3. PubMed PMID: 24029627
Published date: 2014
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.
Raj T, Ryan KJ, Replogle JM, Chibnik LB, Rosenkrantz L, Tang A, Rothamel K, Stranger BE, Bennett DA, Evans DA, De Jager PL, Bradshaw EM
Human molecular genetics 23 (10):2729-36. PubMed PMID: 24381305
Published date: 2013 Dec 30
Cognitive and social lifestyle: links with neuropathology and cognition in late life.
Bennett DA, Arnold SE, Valenzuela MJ, Brayne C, Schneider JA
Acta neuropathologica 127 (1):137-50. PubMed PMID: 24356982
Published date: 2013 Dec 20
Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women.
Bove R, Secor E, Chibnik LB, Barnes LL, Schneider JA, Bennett DA, De Jager PL
Neurology 82 (3):222-9. PubMed PMID: 24336141
Published date: 2013 Dec 11
Evidence needs to be translated, whether or not it is complete.
Dacks PA, Bennett DA, Fillit HM
JAMA neurology 71 (2):137-8. PubMed PMID: 24297103
Published date: 2013 Dec 2
Reply to Itzhaki and Klapper.
Lurain NS, Hanson BA, Martinson J, Leurgans SE, Landay AL, Bennett DA, Schneider JA
The Journal of infectious diseases 209 (6):974. PubMed PMID: 24280368
Published date: 2013 Nov 26
The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
Felsky D, Szeszko P, Yu L, Honer WG, De Jager PL, Schneider JA, Malhotra AK, Lencz T, Ikuta T, Pipitone J, Chakravarty MM, Lobaugh NJ, Mulsant BH, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN
Molecular psychiatry 19 (10):1125-32. PubMed PMID: 24166411
Published date: 2013 Oct 29
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Li
Nature genetics 45 (12):1452-8. PubMed PMID: 24162737
Published date: 2013 Oct 27
TREM2 and neurodegenerative disease.
Reitz C, Mayeux R
The New England journal of medicine 369 (16):1564-5. PubMed PMID: 24131184
Published date: 2013 Oct 17
Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
Yu L, Boyle PA, Leurgans S, Schneider JA, Bennett DA
Neurobiology of aging 35 (4):819-26. PubMed PMID: 24199961
Published date: 2013 Oct 9
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.
Chou SH, Shulman JM, Keenan BT, Secor EA, Buchman AS, Schneider J, Bennett DA, De Jager PL
Cerebrovascular diseases (Basel, Switzerland) 36 (3):181-8. PubMed PMID: 24135527
Published date: 2013
TDP-43 pathology, cognitive decline, and dementia in old age.
Wilson RS, Yu L, Trojanowski JQ, Chen EY, Boyle PA, Bennett DA, Schneider JA
JAMA neurology 70 (11):1418-24. PubMed PMID: 24080705
Published date: 2013 Sep 30
A 2-process model for neuropathology of Alzheimer's disease.
Mungas D, Tractenberg R, Schneider JA, Crane PK, Bennett DA
Neurobiology of aging 35 (2):301-8. PubMed PMID: 24080173
Published date: 2013 Sep 27
Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells.
Zhou L, Wei C, Huang W, Bennett DA, Dickson DW, Wang R, Wang D
American journal of translational research 5 (6):608-621. PubMed PMID: 24093058
Published date: 2013
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wi
Proceedings of the National Academy of Sciences of the United States of America 110 (41):16562-16567. PubMed PMID: 24023061
Published date: 2013 Sep 10
Relation of neuropathology with cognitive decline among older persons without dementia.
Boyle PA, Yu L, Wilson RS, Schneider JA, Bennett DA
Frontiers in aging neuroscience. PubMed PMID: 24058343
Published date: 2013
Cognitive frailty.
Buchman AS, Bennett DA
The journal of nutrition, health & aging 17 (9):738-9. PubMed PMID: 24154644
Published date: 2013
Cerebrospinal fluid tau cleaved by caspase-6 reflects brain levels and cognition in aging and Alzheimer disease.
Ramcharitar J, Albrecht S, Afonso VM, Kaushal V, Bennett DA, Leblanc AC
Journal of neuropathology and experimental neurology 72 (9):824-832. PubMed PMID: 23965742
Published date: 2013 Sep
Charting a dynamic DNA methylation landscape of the human genome.
Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A
Nature 500 (7463):477-81. PubMed PMID: 23925113
Published date: 2013 Aug 7
Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition.
Negash S, Wilson R, Leurgans S, Wolk D, Schneider J, Buchman A, Bennett D, Arnold S
Current Alzheimer research 10 (8):844-851. PubMed PMID: 23919768
Published date: 2013 Aug 6
The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.
Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA, Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C
PLoS genetics 9 (8):e1003685. PubMed PMID: 23990795
Published date: 2013 Aug
Very low levels of education and cognitive reserve: a clinicopathologic study.
Farfel JM, Nitrini R, Suemoto CK, Grinberg LT, Ferretti RE, Leite RE, Tampellini E, Lima L, Farias DS, Neves RC, Rodriguez RD, Menezes PR, Fregni F, Bennett DA, Pasqualucci CA, Jacob Filho W
Neurology 81 (7):650-657. PubMed PMID: 23873971
Published date: 2013 Jul 19
Aging, the central nervous system, and mobility.
Rosso AL, Studenski SA, Chen WG, Aizenstein HJ, Alexander NB, Bennett DA, Black SE, Camicioli R, Carlson MC, Ferrucci L, Guralnik JM, Hausdorff JM, Kaye J, Launer LJ, Lipsitz LA, Verghese J, Rosano C
The journals of gerontology. Series A, Biological sciences and medical sciences 68 (11):1379-86. PubMed PMID: 23843270
Published date: 2013 Jul 10
Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA
JAMA neurology 70 (9):1-7. PubMed PMID: 23836404
Published date: 2013 Jul 8
Caspase-6 activity predicts lower episodic memory ability in aged individuals.
Ramcharitar J, Afonso VM, Albrecht S, Bennett DA, LeBlanc AC
Neurobiology of aging 34 (7):1815-24. PubMed PMID: 23402898
Published date: 2013 Jul
PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ.
Arsenault D, Dal-Pan A, Tremblay C, Bennett DA, Guitton MJ, De Koninck Y, Tonegawa S, Calon F
The Journal of neuroscience : the official journal of the Society for Neuroscience 33 (26):10729-10740. PubMed PMID: 23804095
Published date: 2013 Jun 26
Much of late life cognitive decline is not due to common neurodegenerative pathologies.
Boyle PA, Wilson RS, Yu L, Barr AM, Honer WG, Schneider JA, Bennett DA
Annals of neurology 74 (3):478-489. PubMed PMID: 23798485
Published date: 2013 Jun 24
The red cell distribution width and anemia in association with prevalent dementia.
Weuve J, Mendes de Leon CF, Bennett DA, Dong X, Evans DA
Alzheimer disease and associated disorders 28 (2):99-105. PubMed PMID: 23751369
Published date: 2013 Jun 6
Cognitive decline in older persons initiating anticholinergic medications.
Shah RC, Janos AL, Kline JE, Yu L, Leurgans SE, Wilson RS, Wei P, Bennett DA, Heilman KM, Tsao JW
PloS one 8 (5):e64111. PubMed PMID: 23741303
Published date: 2013
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, E
Science (New York, N.Y.) 340 (6139):1467-1471. PubMed PMID: 23722424
Published date: 2013 May 30
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A, Morris MC, Evans DA, Johnson K, Sperling RA, Schneider JA, Bennett DA, De Jager PL
Nature neuroscience 16 (7):848-50. PubMed PMID: 23708142
Published date: 2013 May 23
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R
Translational psychiatry 3 (5):e256. PubMed PMID: 23673467
Published date: 2013 May 14
Virological and immunological characteristics of human cytomegalovirus infection associated with Alzheimer disease.
Lurain NS, Hanson BA, Martinson J, Leurgans SE, Landay AL, Bennett DA, Schneider JA
The Journal of infectious diseases 208 (4):564-72. PubMed PMID: 23661800
Published date: 2013 May 9
APOE ε4, Alzheimer's disease pathology, cerebrovascular disease, and cognitive change over the years prior to death.
Yu L, Boyle P, Schneider JA, Segawa E, Wilson RS, Leurgans S, Bennett DA
Psychology and aging 28 (4):1015-23. PubMed PMID: 23647000
Published date: 2013 May 6
Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.
Fung WL, Naylor MG, Bennett DA, Lange C, Blacker D
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 162 (7):770-8. PubMed PMID: 23650207
Published date: 2013 May 6
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, Macdonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ,
Cell 153 (3):707-720. PubMed PMID: 23622250
Published date: 2013 Apr 25
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fa
JAMA : the journal of the American Medical Association 309 (14):1483-92. PubMed PMID: 23571587
Published date: 2013 Apr 10
An inflection point in gene discovery efforts for neurodegenerative diseases: from syndromic diagnoses toward endophenotypes and the epigenome.
De Jager PL, Bennett DA
JAMA neurology 70 (6):1-8. PubMed PMID: 23571780
Published date: 2013 Apr 9
Brain amyloid-β oligomers in ageing and Alzheimer's disease.
Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH
Brain : a journal of neurology 136 (Pt 5):1383-98. PubMed PMID: 23576130
Published date: 2013 Apr 9
Estimating cerebral microinfarct burden from autopsy samples.
Westover MB, Bianchi MT, Yang C, Schneider JA, Greenberg SM
Neurology 80 (15):1365-9. PubMed PMID: 23486880
Published date: 2013 Apr 9
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, L
Neuron 78 (2):256-68. PubMed PMID: 23562540
Published date: 2013 Apr 3
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M
PloS one 8 (4):e58618. PubMed PMID: 23565137
Published date: 2013
Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Lim AS, Myers AJ, Yu L, Buchman AS, Duffy JF, De Jager PL, Bennett DA
Journal of biological rhythms 28 (2):117-29. PubMed PMID: 23606611
Published date: 2013 Apr
What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function.
Hausdorff JM, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 68 (4):409-11. PubMed PMID: 23401565
Published date: 2013 Apr
Sleep complaints and incident disability in a community-based cohort study of older persons.
Park M, Buchman AS, Lim AS, Leurgans SE, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 22 (7):718-26. PubMed PMID: 23567404
Published date: 2013 Mar 25
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Green RC
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (1):45-52. PubMed PMID: 23535033
Published date: 2013 Mar 24
Synapse stability in the precuneus early in the progression of Alzheimer's disease.
Scheff SW, Price DA, Schmitt FA, Roberts KN, Ikonomovic MD, Mufson EJ
Journal of Alzheimer's disease : JAD 35 (3):599-609. PubMed PMID: 23478309
Published date: 2013
Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease.
Ertekin-Taner N, De Jager PL, Yu L, Bennett DA
Current genetic medicine reports 1 (1):39-51. PubMed PMID: 23482655
Published date: 2013 Mar
Worship attendance and the disability process in community-dwelling older adults.
Fitchett G, Benjamins MR, Skarupski KA, Mendes de Leon CF
The journals of gerontology. Series B, Psychological sciences and social sciences 68 (2):235-45. PubMed PMID: 23325504
Published date: 2013 Mar
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman E
Annals of human genetics 77 (2):85-105. PubMed PMID: 23360175
Published date: 2013 Mar
Ex vivo MR volumetry of human brain hemispheres.
Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K
Magnetic resonance in medicine 71 (1):364-74. PubMed PMID: 23440751
Published date: 2013 Feb 25
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease.
Bennett DA, Hu WT, Holtzman D, Shaw L, Trojanowski J, Soares H
Neurology 80 (7):690-1. PubMed PMID: 23400321
Published date: 2013 Feb 12
Genome-wide chromatin state transitions associated with developmental and environmental cues.
Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE
Cell 152 (3):642-54. PubMed PMID: 23333102
Published date: 2013 Jan 31
Microvascular brain pathology and late-life motor impairment.
Buchman AS, Yu L, Boyle PA, Levine SR, Nag S, Schneider JA, Bennett DA
Neurology 80 (8):712-8. PubMed PMID: 23365057
Published date: 2013 Jan 30
High blood pressure and cognitive decline in mild cognitive impairment.
Goldstein FC, Levey AI, Steenland NK
Journal of the American Geriatrics Society 61 (1):67-73. PubMed PMID: 23301925
Published date: 2013 Jan
A genome-wide association study of depressive symptoms.
Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Ge
Biological psychiatry 73 (7):667-78. PubMed PMID: 23290196
Published date: 2013 Jan 2
An exploration of clinical dementia phenotypes among individuals with and without traumatic brain injury.
Dams-O'Connor K, Spielman L, Hammond FM, Sayed N, Culver C, Diaz-Arrastia R
NeuroRehabilitation 32 (2):199-209. PubMed PMID: 23535782
Published date: 2013 Jan 1
Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Turk M, Hardy J, Reiman EM, Saykin AJ
PloS one 7 (12):e50640. PubMed PMID: 23227193
Published date: 2012
AD pathology and cerebral infarctions are associated with memory and executive functioning one and five years before death.
Yang FM, Grigorenko A, Tommet D, Farias ST, Mungas D, Bennett DA, Jones RN, Crane PK
Journal of clinical and experimental neuropsychology 35 (1):24-34. PubMed PMID: 23205616
Published date: 2012 Dec 3
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, Brayne C, Gill M, Lawlor B, Lynch A, Craig D, McGuinness B, Johnston J, Holmes C, Living
Molecular psychiatry 17 (12):1316-27. PubMed PMID: 22005930
Published date: 2012 Dec
The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.
Larson M, Sherman MA, Amar F, Nuvolone M, Schneider JA, Bennett DA, Aguzzi A, Lesné SE
The Journal of neuroscience : the official journal of the Society for Neuroscience 32 (47):16857-16871. PubMed PMID: 23175838
Published date: 2012 Nov 21
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
Whitcomb DC, Larusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Albert MS, Albin RL, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barnes LL, Beach TG, Beecham GW, Beekly D, B
Nature genetics 44 (12):1349-54. PubMed PMID: 23143602
Published date: 2012 Nov 11
Trends in Alzheimer's disease and dementia in the asian-pacific region.
Aggarwal NT, Tripathi M, Dodge HH, Alladi S, Anstey KJ
International journal of Alzheimer's disease. PubMed PMID: 23304631
Published date: 2012
Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study.
Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR
Neuroepidemiology 40 (2):73-84. PubMed PMID: 23095514
Published date: 2012 Oct 24
Molecular mechanisms of cortical degeneration in Parkinson disease.
Shulman JM, Schneider JA
Neurology 79 (17):1750-1. PubMed PMID: 23019261
Published date: 2012 Oct 23
GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.
Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Trojanowski JQ, Schellenberg GD, Yearout D, Huston
Neurology 79 (19):1944-1950. PubMed PMID: 23035075
Published date: 2012 Oct 3
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies.
Schneider JA, Arvanitakis Z, Yu L, Boyle PA, Leurgans SE, Bennett DA
Brain : a journal of neurology 135 (Pt 10):3005-14. PubMed PMID: 23065790
Published date: 2012 Oct
Relation of neuropathology to cognition in persons without cognitive impairment.
Bennett DA, Wilson RS, Boyle PA, Buchman AS, Schneider JA
Annals of neurology 72 (4):599-609. PubMed PMID: 23109154
Published date: 2012 Oct
The natural history of cognitive decline in Alzheimer's disease.
Wilson RS, Segawa E, Boyle PA, Anagnos SE, Hizel LP, Bennett DA
Psychology and aging 27 (4):1008-17. PubMed PMID: 22946521
Published date: 2012 Sep 3
Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family Study.
Swaminathan S, Shen L, Kim S, Inlow M, West JD, Faber KM, Foroud T, Mayeux R, Saykin AJ
Current Alzheimer research 9 (7):801-14. PubMed PMID: 22486522
Published date: 2012 Sep
High CRP with "normal" cognition: a resilient phenotype in old age.
Buchman AS, Bennett DA
Neurology 79 (11):1078-9. PubMed PMID: 22895579
Published date: 2012 Aug 15
Reply.
Buchman AS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA
Annals of neurology 72 (2):298. PubMed PMID: 22926865
Published date: 2012 Aug
Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
Larson ME, Sherman MA, Greimel S, Kuskowski M, Schneider JA, Bennett DA, Lesné SE
The Journal of neuroscience : the official journal of the Society for Neuroscience 32 (30):10253-66. PubMed PMID: 22836259
Published date: 2012 Jul 25
Overview and findings from the religious orders study.
Bennett DA, Schneider JA, Arvanitakis Z, Wilson RS
Current Alzheimer research 9 (6):628-45. PubMed PMID: 22471860
Published date: 2012 Jul
The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia.
Barnes LL, Shah RC, Aggarwal NT, Bennett DA, Schneider JA
Current Alzheimer research 9 (6):734-45. PubMed PMID: 22471868
Published date: 2012 Jul
Age-related changes in parahippocampal white matter integrity: a diffusion tensor imaging study.
Rogalski E, Stebbins GT, Barnes CA, Murphy CM, Stoub TR, George S, Ferrari C, Shah RC, deToledo-Morrell L
Neuropsychologia 50 (8):1759-65. PubMed PMID: 22561887
Published date: 2012 Jul
Longitudinal epidemiologic clinical-pathologic studies of aging and Alzheimer's disease.
Bennett DA, Launer LJ
Current Alzheimer research 9 (6):617-20. PubMed PMID: 22715984
Published date: 2012 Jul
Alzheimer's disease can spare local metacognition despite global anosognosia: revisiting the confidence-accuracy relationship in episodic memory.
Gallo DA, Cramer SJ, Wong JT, Bennett DA
Neuropsychologia 50 (9):2356-64. PubMed PMID: 22722068
Published date: 2012 Jul
Age-related changes in the mesial temporal lobe: the parahippocampal white matter region.
Stoub TR, Barnes CA, Shah RC, Stebbins GT, Ferrari C, deToledo-Morrell L
Neurobiology of aging 33 (7):1168-76. PubMed PMID: 21459484
Published date: 2012 Jul
TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease.
Valant V, Keenan BT, Anderson CD, Shulman JM, Devan WJ, Ayres AM, Schwab K, Goldstein JN, Viswanathan A, Greenberg SM, Bennett DA, De Jager PL, Rosand J, Biffi A
Translational stroke research 3 (Suppl 1):102-12. PubMed PMID: 24323865
Published date: 2012 Jul
Selected findings from the Religious Orders Study and Rush Memory and Aging Project.
Bennett DA, Wilson RS, Arvanitakis Z, Boyle PA, de Toledo-Morrell L, Schneider JA
Journal of Alzheimer's disease : JAD 33 (0):S397-403. PubMed PMID: 22647261
Published date: 2012 May 29
Terminal decline in motor function.
Wilson RS, Segawa E, Buchman AS, Boyle PA, Hizel LP, Bennett DA
Psychology and aging 27 (4):998-1007. PubMed PMID: 22612603
Published date: 2012 May 21
Dementia from Alzheimer disease and mixed pathologies in the oldest old.
James BD, Bennett DA, Boyle PA, Leurgans S, Schneider JA
JAMA 307 (17):1798-800. PubMed PMID: 22550192
Published date: 2012 May 2
Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
Arnold SE, Louneva N, Cao K, Wang LS, Han LY, Wolk DA, Negash S, Leurgans SE, Schneider JA, Buchman AS, Wilson RS, Bennett DA
Neurobiology of aging 34 (1):157-68. PubMed PMID: 22554416
Published date: 2012 May 1
Common variants at 12q14 and 12q24 are associated with hippocampal volume.
Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA
Nature genetics 44 (5):545-51. PubMed PMID: 22504421
Published date: 2012 May
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.
Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kövari E, Kukull WA, Leverenz
Journal of neuropathology and experimental neurology 71 (5):362-81. PubMed PMID: 22487856
Published date: 2012 May
Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y, Wilson RS, Foroud T, Ott J, Mayeux R
Neurology 78 (19):1464-1471. PubMed PMID: 22539578
Published date: 2012 Apr 25
Terminal dedifferentiation of cognitive abilities.
Wilson RS, Segawa E, Hizel LP, Boyle PA, Bennett DA
Neurology 78 (15):1116-22. PubMed PMID: 22491858
Published date: 2012 Apr 10
Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
Raj T, Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, De Jager PL
American journal of human genetics 90 (4):720-6. PubMed PMID: 22482808
Published date: 2012 Apr 6
Hippocampal drebrin loss in mild cognitive impairment.
Counts SE, He B, Nadeem M, Wuu J, Scheff SW, Mufson EJ
Neuro-degenerative diseases 10 (1-4):216-9. PubMed PMID: 22310934
Published date: 2012
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE
The Journal of clinical investigation 122 (4):1316-38. PubMed PMID: 22476197
Published date: 2012 Mar 22
Cerebral microinfarcts: the invisible lesions.
Smith EE, Schneider JA, Wardlaw JM, Greenberg SM
The Lancet. Neurology 11 (3):272-82. PubMed PMID: 22341035
Published date: 2012 Mar
Cerebral microinfarcts: the invisible lesions.
Smith EE, Schneider JA, Wardlaw JM, Greenberg SM
The Lancet. Neurology 11 (3):272-82. PubMed PMID: 22341035
Published date: 2012 Mar
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Pankratz N, Beecham GW, DeStefano AL, Dawson TM, Doheny KF, Factor SA, Hamza TH, Hung AY, Hyman BT, Ivinson AJ, Krainc D, Latourelle JC, Clark LN, Marder K, Martin ER, Mayeux R, Ross OA, Scherzer CR, Simon DK, Tanner C, Vance JM, Wszolek ZK, Zabetian
Annals of neurology 71 (3):370-84. PubMed PMID: 22451204
Published date: 2012 Mar
Patterns of focal gray matter atrophy are associated with bradykinesia and gait disturbances in older adults.
Rosano C, Bennett DA, B Newman A, Venkatraman V, Yaffe K, Harris T, Kritchevsky S, J Aizenstein H
The journals of gerontology. Series A, Biological sciences and medical sciences 67 (9):957-62. PubMed PMID: 22367436
Published date: 2012 Feb 24
Plasma biomarkers of depressive symptoms in older adults.
Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, Wilson RS, Shaw LM
Translational psychiatry 2 (1):e65. PubMed PMID: 22832727
Published date: 2012 Feb 21
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline.
Keenan BT, Shulman JM, Chibnik LB, Raj T, Tran D, Sabuncu MR, Allen AN, Corneveaux JJ, Hardy JA, Huentelman MJ, Lemere CA, Myers AJ, Nicholson-Weller A, Reiman EM, Evans DA, Bennett DA, De Jager PL
Human molecular genetics 21 (10):2377-2388. PubMed PMID: 22343410
Published date: 2012 Feb 17
Nigral pathology and parkinsonian signs in elders without Parkinson disease.
Buchman AS, Shulman JM, Nag S, Leurgans SE, Arnold SE, Morris MC, Schneider JA, Bennett DA
Annals of neurology 71 (2):258-66. PubMed PMID: 22367997
Published date: 2012 Feb
Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families.
Cruchaga C, Haller G, Chakraverty S, Mayo K, Vallania FL, Mitra RD, Faber K, Williamson J, Bird T, Diaz-Arrastia R, Foroud TM, Boeve BF, Graff-Radford NR, St Jean P, Lawson M, Ehm MG, Mayeux R, Goate AM
PloS one 7 (2):e31039. PubMed PMID: 22312439
Published date: 2012
Recruitment and enrollment of caregivers for a lifestyle physical activity clinical trial.
Etkin CD, Farran CJ, Barnes LL, Shah RC
Research in nursing & health 35 (1):70-81. PubMed PMID: 22083931
Published date: 2012 Feb
Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease.
Perez SE, Getova DP, He B, Counts SE, Geula C, Desire L, Coutadeur S, Peillon H, Ginsberg SD, Mufson EJ
The American journal of pathology 180 (2):526-40. PubMed PMID: 22142809
Published date: 2012 Feb
Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.
Biffi A, Shulman JM, Jagiella JM, Cortellini L, Ayres AM, Schwab K, Brown DL, Silliman SL, Selim M, Worrall BB, Meschia JF, Slowik A, De Jager PL, Greenberg SM, Schneider JA, Bennett DA, Rosand J
Neurology 78 (5):334-41. PubMed PMID: 22262751
Published date: 2012 Jan 31
Amyloid pathology in persons with "normal" cognition.
Buchman AS, Bennett DA
Neurology 78 (4):228-229. PubMed PMID: 22189449
Published date: 2012 Jan 24
Mild cognitive impairment: pathology and mechanisms.
Mufson EJ, Binder L, Counts SE, DeKosky ST, de Toledo-Morrell L, Ginsberg SD, Ikonomovic MD, Perez SE, Scheff SW
Acta neuropathologica 123 (1):13-30. PubMed PMID: 22101321
Published date: 2012 Jan
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach.
Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, Hyman BT
Acta neuropathologica 123 (1):1-11. PubMed PMID: 22101365
Published date: 2012 Jan
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.
Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, Trojanowski JQ, Vinters HV, Montine TJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 8 (1):1-13. PubMed PMID: 22265587
Published date: 2012 Jan
Correlation of amyloid PET ligand florbetapir F 18 binding with Aβ aggregation and neuritic plaque deposition in postmortem brain tissue.
Choi SR, Schneider JA, Bennett DA, Beach TG, Bedell BJ, Zehntner SP, Krautkramer MJ, Kung HF, Skovronsky DM, Hefti F, Clark CM
Alzheimer disease and associated disorders 26 (1):8-16. PubMed PMID: 22354138
Published date: 2012 Jan
A random change point model for cognitive decline in Alzheimer's disease and mild cognitive impairment.
Yu L, Boyle P, Wilson RS, Segawa E, Leurgans S, De Jager PL, Bennett DA
Neuroepidemiology 39 (2):73-83. PubMed PMID: 22814083
Published date: 2012
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Perica
PLoS genetics 8 (6):e1002707. PubMed PMID: 22685416
Published date: 2012
Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease.
Huang JY, Hafez DM, James BD, Bennett DA, Marr RA
Journal of Alzheimer's disease : JAD 28 (2):433-41. PubMed PMID: 22008264
Published date: 2012 Jan 1
Evidence for angiogenesis in Parkinson's disease, incidental Lewy body disease, and progressive supranuclear palsy.
Desai Bradaric B, Patel A, Schneider JA, Carvey PM, Hendey B
Journal of neural transmission (Vienna, Austria : 1996) 119 (1):59-71. PubMed PMID: 21748523
Published date: 2012 Jan
A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ, Rosand J, Daly MJ, Myers AJ, Reiman EM, Bennett DA, Evans DA
Neurobiology of aging 33 (5):1017.e1-1017.e15. PubMed PMID: 22054870
Published date: 2011 Nov 3
Cerebrovascular disease pathology and parkinsonian signs in old age.
Buchman AS, Leurgans SE, Nag S, Bennett DA, Schneider JA
Stroke 42 (11):3183-9. PubMed PMID: 21885844
Published date: 2011 Nov
Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Vana L, Kanaan NM, Ugwu IC, Wuu J, Mufson EJ, Binder LI
The American journal of pathology 179 (5):2533-50. PubMed PMID: 21945902
Published date: 2011 Nov
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, Dejager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S
Science (New York, N.Y.) 334 (6060):1241-5. PubMed PMID: 22033521
Published date: 2011 Oct 27
Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Mufson EJ, Alldred MJ, Counts SE, Wuu J, Nixon RA, Che S
Journal of chemical neuroanatomy 42 (2):102-10. PubMed PMID: 21669283
Published date: 2011 Oct
Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease.
Counts SE, Che S, Ginsberg SD, Mufson EJ
Journal of chemical neuroanatomy 42 (2):111-7. PubMed PMID: 21397006
Published date: 2011 Oct
Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease.
Counts SE, Che S, Ginsberg SD, Mufson EJ
Journal of chemical neuroanatomy 42 (2):111-7. PubMed PMID: 21397006
Published date: 2011 Oct
Cognitive decline in the elderly: an analysis of population heterogeneity.
Hayden KM, Reed BR, Manly JJ, Tommet D, Pietrzak RH, Chelune GJ, Yang FM, Revell AJ, Bennett DA, Jones RN
Age and ageing 40 (6):684-9. PubMed PMID: 21890481
Published date: 2011 Sep 2
Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease.
Tremblay C, St-Amour I, Schneider J, Bennett DA, Calon F
Journal of neuropathology and experimental neurology 70 (9):788-98. PubMed PMID: 21865887
Published date: 2011 Sep
Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them.
Reid MC, Bennett DA, Chen WG, Eldadah BA, Farrar JT, Ferrell B, Gallagher RM, Hanlon JT, Herr K, Horn SD, Inturrisi CE, Lemtouni S, Lin YW, Michaud K, Morrison RS, Neogi T, Porter LL, Solomon DH, Von Korff M, Weiss K, Witter J, Zacharoff KL
Pain medicine (Malden, Mass.) 12 (9):1336-1357. PubMed PMID: 21834914
Published date: 2011 Aug 11
ELISA measurement of specific non-antigen-bound antibodies to Aβ1-42 monomer and soluble oligomers in sera from Alzheimer's disease, mild cognitively impaired, and noncognitively impaired subjects.
Klaver AC, Coffey MP, Smith LM, Bennett DA, Finke JM, Dang L, Loeffler DA
Journal of neuroinflammation 8 (1):93. PubMed PMID: 21827691
Published date: 2011 Aug 9
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.
Gorelick PB, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, Launer LJ, Laurent S, Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C, Arnett DK, Bennett DA, Chui HC, Higashida RT, Lindquist R, Nilsson PM, Roman GC, Sellke FW, Sesha
Stroke 42 (9):2672-2713. PubMed PMID: 21778438
Published date: 2011 Jul 21
Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease.
Ikonomovic MD, Klunk WE, Abrahamson EE, Wuu J, Mathis CA, Scheff SW, Mufson EJ, DeKosky ST
Neurology 77 (1):39-47. PubMed PMID: 21700583
Published date: 2011 Jul 5
Datasets for special series on cognitive reserve.
Bennett DA, Barnes LL
Journal of the International Neuropsychological Society : JINS 17 (4):587-92. PubMed PMID: 23131599
Published date: 2011 Jul
Cognitive activities during adulthood are more important than education in building reserve.
Reed BR, Dowling M, Tomaszewski Farias S, Sonnen J, Strauss M, Schneider JA, Bennett DA, Mungas D
Journal of the International Neuropsychological Society : JINS 17 (4):615-24. PubMed PMID: 23131600
Published date: 2011 Jul
Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
Ewers M, Schmitz S, Hansson O, Walsh C, Fitzpatrick A, Bennett D, Minthon L, Trojanowski JQ, Shaw LM, Faluyi YO, Vellas B, Dubois B, Blennow K, Buerger K, Teipel SJ, Weiner M, Hampel H
Neurobiology of aging 33 (8):1599-608. PubMed PMID: 21684041
Published date: 2011 Jun 16
Uncovering the genetic architecture of white matter disease.
Aggarwal NT, De Jager PL
Annals of neurology 69 (6):907-8. PubMed PMID: 21681793
Published date: 2011 Jun
Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment.
Trivedi MA, Stoub TR, Murphy CM, George S, deToledo-Morrell L, Shah RC, Whitfield-Gabrieli S, Gabrieli JD, Stebbins GT
Brain imaging and behavior 5 (2):126-36. PubMed PMID: 21328083
Published date: 2011 Jun
Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project.
Negash S, Bennett DA, Wilson RS, Schneider JA, Arnold SE
Current Alzheimer research 8 (4):336-40. PubMed PMID: 21222592
Published date: 2011 Jun
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kau
Nature genetics 43 (5):436-41. PubMed PMID: 21460841
Published date: 2011 May
Assessing family caregiver skill in managing behavioral symptoms of Alzheimer's disease.
Farran CJ, Fogg LG, McCann JJ, Etkin C, Dong X, Barnes LL
Aging & mental health 15 (4):510-21. PubMed PMID: 21500018
Published date: 2011 May
Loss of motor function in preclinical Alzheimer's disease.
Buchman AS, Bennett DA
Expert review of neurotherapeutics 11 (5):665-76. PubMed PMID: 21539487
Published date: 2011 May
Assessment of cognition in early dementia.
Silverberg NB, Ryan LM, Carrillo MC, Sperling R, Petersen RC, Posner HB, Snyder PJ, Hilsabeck R, Gallagher M, Raber J, Rizzo A, Possin K, King J, Kaye J, Ott BR, Albert MS, Wagster MV, Schinka JA, Cullum CM, Farias ST, Balota D, Rao S, Loewenstein D,
Alzheimer's & dementia : the journal of the Alzheimer's Association 7 (3):e60-e76. PubMed PMID: 23559893
Published date: 2011 May 1
Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.
Bruno AM, Huang JY, Bennett DA, Marr RA, Hastings ML, Stutzmann GE
Neurobiology of aging 33 (5):1001.e1-6. PubMed PMID: 21531043
Published date: 2011 Apr 29
Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults.
Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L
Neurology 76 (16):1395-402. PubMed PMID: 21490323
Published date: 2011 Apr 19
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.
Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, Gearing M, Beach TG, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF,
Archives of neurology 68 (4):488-97. PubMed PMID: 21482928
Published date: 2011 Apr
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.
Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, Gearing M, Beach TG, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF,
Archives of neurology 68 (4):488-97. PubMed PMID: 21482928
Published date: 2011 Apr
Smoking in midlife and dementia in old age: risk across the life course.
James BD, Bennett DA
Archives of neurology 68 (3):365-8. PubMed PMID: 21403022
Published date: 2011 Mar
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, Hardy JA, Huentelman MJ, Corneveaux JJ, Reiman EM, Evans DA, Bennett DA, De Jager PL
Annals of neurology 69 (3):560-9. PubMed PMID: 21391232
Published date: 2011 Mar
Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment.
Wilson RS, Leurgans SE, Boyle PA, Bennett DA
Archives of neurology 68 (3):351-6. PubMed PMID: 21403020
Published date: 2011 Mar
Microinfarct pathology, dementia, and cognitive systems.
Arvanitakis Z, Leurgans SE, Barnes LL, Bennett DA, Schneider JA
Stroke 42 (3):722-7. PubMed PMID: 21212395
Published date: 2011 Mar
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL
American journal of human genetics 88 (2):232-8. PubMed PMID: 21295279
Published date: 2011 Feb 11
Analysis of postmortem ventricular cerebrospinal fluid from patients with and without dementia indicates association of vitamin E with neuritic plaques and specific measures of cognitive performance.
Hensley K, Barnes LL, Christov A, Tangney C, Honer WG, Schneider JA, Bennett DA, Morris MC
Journal of Alzheimer's disease : JAD 24 (4):767-74. PubMed PMID: 21321395
Published date: 2011
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, Mayeux R
PLoS genetics 7 (2):e1001308. PubMed PMID: 21379329
Published date: 2011 Feb
Cerebral amyloid angiopathy pathology and cognitive domains in older persons.
Arvanitakis Z, Leurgans SE, Wang Z, Wilson RS, Bennett DA, Schneider JA
Annals of neurology 69 (2):320-7. PubMed PMID: 21387377
Published date: 2011 Feb
Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer's disease.
Scheff SW, Price DA, Schmitt FA, Scheff MA, Mufson EJ
Journal of Alzheimer's disease : JAD 24 (3):547-57. PubMed PMID: 21297265
Published date: 2011
Musculoskeletal pain is associated with incident mobility disability in community-dwelling elders.
Shah RC, Buchman AS, Boyle PA, Leurgans SE, Wilson RS, Andersson GB, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 66 (1):82-8. PubMed PMID: 20966101
Published date: 2011 Jan
Heritability of different forms of memory in the Late Onset Alzheimer's Disease Family Study.
Wilson RS, Barral S, Lee JH, Leurgans SE, Foroud TM, Sweet RA, Graff-Radford N, Bird TD, Mayeux R, Bennett DA
Journal of Alzheimer's disease : JAD 23 (2):249-55. PubMed PMID: 20930268
Published date: 2011
Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study.
Dawe RJ, Bennett DA, Schneider JA, Arfanakis K
PloS one 6 (10):e26286. PubMed PMID: 22043314
Published date: 2011
Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults.
Dowling NM, Tomaszewski Farias S, Reed BR, Sonnen JA, Strauss ME, Schneider JA, Bennett DA, Mungas D
Journal of the International Neuropsychological Society : JINS 17 (4):1-13. PubMed PMID: 21092373
Published date: 2010 Nov 22
Antemortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies.
Kantarci K, Yang C, Schneider JA, Senjem ML, Reyes DA, Lowe VJ, Barnes LL, Aggarwal NT, Bennett DA, Smith GE, Petersen RC, Jack CR, Boeve BF
Neurobiology of aging 33 (5):878-85. PubMed PMID: 20961664
Published date: 2010 Oct 18
Relation of cardiac ventricular repolarization and global cognitive performance in a community population.
Lucas BP, Mendes de Leon CF, Prineas RJ, Bienias JL, Evans DA
The American journal of cardiology 106 (8):1169-73. PubMed PMID: 20920659
Published date: 2010 Oct 15
False recollection of emotional pictures in Alzheimer's disease.
Gallo DA, Foster KT, Wong JT, Bennett DA
Neuropsychologia 48 (12):3614-8. PubMed PMID: 20727904
Published date: 2010 Oct
Where vascular meets neurodegenerative disease.
Schneider JA, Bennett DA
Stroke 41 (10 Suppl):S144-6. PubMed PMID: 20876491
Published date: 2010 Oct
Is there a link between cancer and Alzheimer disease?
Bennett DA
Neurology 75 (13):1216-7. PubMed PMID: 20922851
Published date: 2010 Sep 28
Neurodegenerative basis of age-related cognitive decline.
Wilson RS, Leurgans SE, Boyle PA, Schneider JA, Bennett DA
Neurology 75 (12):1070-8. PubMed PMID: 20844243
Published date: 2010 Sep 21
Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Mufson EJ, Counts SE, Wuu J, Alldred MJ, Nixon RA, Che S
Journal of Alzheimer's disease : JAD 22 (2):631-639. PubMed PMID: 20847427
Published date: 2010 Aug 30
Loss of basic lexical knowledge in old age.
Wilson RS, Krueger KR, Boyle PA, Bennett DA
Journal of neurology, neurosurgery, and psychiatry 82 (4):369-72. PubMed PMID: 20802026
Published date: 2010 Aug 27
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Ma
Archives of neurology 67 (12):1473-1484. PubMed PMID: 20697030
Published date: 2010 Aug 9
Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression.
Ginsberg SD, Alldred MJ, Counts SE, Cataldo AM, Neve RL, Jiang Y, Wuu J, Chao MV, Mufson EJ, Nixon RA, Che S
Biological psychiatry 68 (10):885-93. PubMed PMID: 20655510
Published date: 2010 Jul 22
Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.
Wang S, Wang R, Chen L, Bennett DA, Dickson DW, Wang DS
Journal of neurochemistry 115 (1):47-57. PubMed PMID: 20663017
Published date: 2010 Jul 17
Iterative image reconstruction for PROPELLER-MRI using the nonuniform fast fourier transform.
Tamhane AA, Anastasio MA, Gui M, Arfanakis K
Journal of magnetic resonance imaging : JMRI 32 (1):211-7. PubMed PMID: 20578028
Published date: 2010 Jul
Telephone assessment of cognitive function in the late-onset Alzheimer's disease family study.
Wilson RS, Leurgans SE, Foroud TM, Sweet RA, Graff-Radford N, Mayeux R, Bennett DA
Archives of neurology 67 (7):855-61. PubMed PMID: 20625093
Published date: 2010 Jul
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley
Human molecular genetics 19 (16):3295-301. PubMed PMID: 20534741
Published date: 2010 Jun 9
Staff training in assisted living: evaluating treatment fidelity.
Teri L, McKenzie GL, Pike KC, Farran CJ, Beck C, Paun O, Lafazia D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 18 (6):502-9. PubMed PMID: 19910884
Published date: 2010 Jun
Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J
Neurobiology of aging 32 (12):2113-22. PubMed PMID: 20452100
Published date: 2010 May 6
Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans.
Soetanto A, Wilson RS, Talbot K, Un A, Schneider JA, Sobiesk M, Kelly J, Leurgans S, Bennett DA, Arnold SE
Archives of general psychiatry 67 (5):448-57. PubMed PMID: 20439826
Published date: 2010 May
Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation.
Halawani D, Tessier S, Anzellotti D, Bennett DA, Latterich M, LeBlanc AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 30 (17):6132-42. PubMed PMID: 20427671
Published date: 2010 Apr 28
Inability of plasma and urine F2A-isoprostane levels to differentiate mild cognitive impairment from Alzheimer's disease.
Mufson EJ, Leurgans S
Neuro-degenerative diseases 7 (1-3):139-42. PubMed PMID: 20197693
Published date: 2010
Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease.
Wang C, Stebbins GT, Medina DA, Shah RC, Bammer R, Moseley ME, Detoledo-Morrell L
Neurobiology of aging 33 (1):43-52. PubMed PMID: 20359781
Published date: 2010 Mar 30
Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease.
Overk CR, Felder CC, Tu Y, Schober DA, Bales KR, Wuu J, Mufson EJ
Journal of chemical neuroanatomy 40 (1):63-70. PubMed PMID: 20347961
Published date: 2010 Mar 27
Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.
Mufson EJ, Wuu J, Counts SE, Nykjaer A
Neuroscience letters 471 (3):129-33. PubMed PMID: 20085800
Published date: 2010 Mar 8
Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.
Mufson EJ, Wuu J, Counts SE, Nykjaer A
Neuroscience letters 471 (3):129-33. PubMed PMID: 20085800
Published date: 2010 Mar 8
PUTATIVE CSF PROTEIN BIOMARKER CANDIDATES FOR AMNESTIC MILD COGNITIVE IMPAIRMENT.
Counts SE, Mufson EJ
Translational neuroscience 1 (1):2-8. PubMed PMID: 21311725
Published date: 2010 Mar 1
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafm
Nature genetics 42 (3):234-9. PubMed PMID: 20154673
Published date: 2010 Feb 14
Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study.
Sweet RA, Bennett DA, Graff-Radford NR, Mayeux R
Brain : a journal of neurology 133 (Pt 4):1155-1162. PubMed PMID: 20147454
Published date: 2010 Feb 10
Parkinsonian signs and incident falls in older persons without Parkinson's disease.
Buracchio T, Arvanitakis Z, Leurgans S, Bennett DA
Journal of the American Geriatrics Society 58 (1):205-6. PubMed PMID: 20122072
Published date: 2010 Jan
Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
Shulman JM, Chibnik LB, Aubin C, Schneider JA, Bennett DA, De Jager PL
PloS one 5 (6):e11244. PubMed PMID: 20574532
Published date: 2010
Neuroprotective role for galanin in Alzheimer's disease.
Counts SE, Perez SE, Ginsberg SD, Mufson EJ
Experientia supplementum (2012) 102 (11):143-62. PubMed PMID: 21299067
Published date: 2010
Neuroprotective role for galanin in Alzheimer's disease.
Counts SE, Perez SE, Ginsberg SD, Mufson EJ
Experientia supplementum (2012) 102 (11):143-62. PubMed PMID: 21299067
Published date: 2010
Is there a link between cancer and Alzheimer disease?
Bennett DA, Leurgans S
Neurology 74 (2):100-1. PubMed PMID: 20032287
Published date: 2009 Dec 23
Subregional neuroanatomical change as a biomarker for Alzheimer's disease.
Holland D, Brewer JB, Hagler DJ, Fenema-Notestine C, Dale AM, Weiner M, Thal L, Petersen R, Jack CR, Jagust W, Trojanowki J, Toga AW, Beckett L, Green RC, Gamst A, Potter WZ, Montine T, Anders D, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, A
Proceedings of the National Academy of Sciences of the United States of America 106 (49):20954-20959. PubMed PMID: 19996185
Published date: 2009 Dec 8
Increased matrix metalloproteinase 9 activity in mild cognitive impairment.
Bruno MA, Mufson EJ, Wuu J, Cuello AC
Journal of neuropathology and experimental neurology 68 (12):1309-18. PubMed PMID: 19915485
Published date: 2009 Dec
Increased matrix metalloproteinase 9 activity in mild cognitive impairment.
Bruno MA, Mufson EJ, Wuu J, Cuello AC
Journal of neuropathology and experimental neurology 68 (12):1309-18. PubMed PMID: 19915485
Published date: 2009 Dec
Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Journal of Alzheimer's disease : JAD 18 (4):885-96. PubMed PMID: 19749437
Published date: 2009 Dec
Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Journal of Alzheimer's disease : JAD 18 (4):885-96. PubMed PMID: 19749437
Published date: 2009 Dec
The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons.
Boyle PA, Buchman AS, Wilson RS, Kelly JF, Bennett DA
Neuroepidemiology 34 (1):43-9. PubMed PMID: 19907191
Published date: 2010
High blood pressure and microinfarcts: a link between vascular risk factors, dementia, and clinical Alzheimer's disease.
Schneider JA
Journal of the American Geriatrics Society 57 (11):2146-7. PubMed PMID: 20121957
Published date: 2009 Nov
A battery of tests for assessing cognitive function in older Latino persons.
Krueger KR, Wilson RS, Bennett DA, Aggarwal NT
Alzheimer disease and associated disorders 23 (4):384-8. PubMed PMID: 19561439
Published date: 2009 Oct-Dec
Kidney function is associated with the rate of cognitive decline in the elderly.
Buchman AS, Tanne D, Boyle PA, Shah RC, Leurgans SE, Bennett DA
Neurology 73 (12):920-7. PubMed PMID: 19657107
Published date: 2009 Sep 22
The neuropathology of older persons with and without dementia from community versus clinic cohorts.
Schneider JA, Aggarwal NT, Barnes L, Boyle P, Bennett DA
Journal of Alzheimer's disease : JAD 18 (3):691-701. PubMed PMID: 19749406
Published date: 2009
Race differences in emotional adaptation of family caregivers.
Skarupski KA, McCann JJ, Bienias JL, Evans DA
Aging & mental health 13 (5):715-24. PubMed PMID: 19882410
Published date: 2009 Sep
The neuropathology of probable Alzheimer disease and mild cognitive impairment.
Schneider JA, Arvanitakis Z, Leurgans SE, Bennett DA
Annals of neurology 66 (2):200-8. PubMed PMID: 19743450
Published date: 2009 Aug
Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1.
Hascalovici JR, Vaya J, Khatib S, Holcroft CA, Zukor H, Song W, Arvanitakis Z, Bennett DA, Schipper HM
Journal of neurochemistry 110 (4):1241-53. PubMed PMID: 19522732
Published date: 2009 Jun 9
NSAID exposure and risk of Alzheimer disease: is timing everything?
Bennett DA, Whitmer RA
Neurology 72 (22):1884-5. PubMed PMID: 19386996
Published date: 2009 Jun 2
Purpose in life is associated with mortality among community-dwelling older persons.
Boyle PA, Barnes LL, Buchman AS, Bennett DA
Psychosomatic medicine 71 (5):574-9. PubMed PMID: 19414613
Published date: 2009 Jun
Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.
Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST
Archives of neurology 66 (5):646-51. PubMed PMID: 19433665
Published date: 2009 May
Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.
Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST
Archives of neurology 66 (5):646-51. PubMed PMID: 19433665
Published date: 2009 May
Improving dementia care in assisted living residences: addressing staff reactions to training.
Teri L, McKenzie GL, LaFazia D, Farran CJ, Beck C, Huda P, van Leynseele J, Pike KC
Geriatric nursing (New York, N.Y.) 30 (3):153-63. PubMed PMID: 19520226
Published date: 2009 May-Jun
Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles.
Bennett DA, De Jager PL, Leurgans SE, Schneider JA
Neurology 72 (17):1495-503. PubMed PMID: 19398704
Published date: 2009 Apr 28
Evidence of angiogenic vessels in Alzheimer's disease.
Desai BS, Schneider JA, Li JL, Carvey PM, Hendey B
Journal of neural transmission (Vienna, Austria : 1996) 116 (5):587-97. PubMed PMID: 19370387
Published date: 2009 Apr 16
Genetic control of human brain transcript expression in Alzheimer disease.
Webster JA, Gibbs JR, Clarke J, Ray M, Zhang W, Holmans P, Rohrer K, Zhao A, Marlowe L, Kaleem M, McCorquodale DS, Cuello C, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Heward CB, Reim
American journal of human genetics 84 (4):445-58. PubMed PMID: 19361613
Published date: 2009 Apr
The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test battery.
Weintraub S, Salmon D, Mercaldo N, Ferris S, Graff-Radford NR, Chui H, Cummings J, DeCarli C, Foster NL, Galasko D, Peskind E, Dietrich W, Beekly DL, Kukull WA, Morris JC
Alzheimer disease and associated disorders 23 (2):91-101. PubMed PMID: 19474567
Published date: 2009 Apr-Jun
The Spanish translation and adaptation of the Uniform Data Set of the National Institute on Aging Alzheimer's Disease Centers.
Acevedo A, Krueger KR, Navarro E, Ortiz F, Manly JJ, Padilla-Vélez MM, Weintraub S, López OL, Mungas D
Alzheimer disease and associated disorders 23 (2):102-9. PubMed PMID: 19474568
Published date: 2009 Apr-Jun
Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation.
Dawe RJ, Bennett DA, Schneider JA, Vasireddi SK, Arfanakis K
Magnetic resonance in medicine 61 (4):810-8. PubMed PMID: 19189294
Published date: 2009 Apr
Early risk assessment for Alzheimer's disease.
Carrillo MC, Blackwell A, Hampel H, Lindborg J, Sperling R, Schenk D, Sevigny JJ, Ferris S, Bennett DA, Craft S, Hsu T, Klunk W
Alzheimer's & dementia : the journal of the Alzheimer's Association 5 (2):182-96. PubMed PMID: 19328456
Published date: 2009 Mar
Visuoperceptual repetition priming and progression of parkinsonian signs in aging.
Fleischman DA, Buchman AS, Bienias JL, Bennett DA
Neurobiology of aging 30 (3):441-9. PubMed PMID: 17709154
Published date: 2009 Mar
Repetition priming and change in functional ability in older persons without dementia.
Fleischman DA, Bienias JL, Bennett DA
Neuropsychology 23 (1):98-104. PubMed PMID: 19210037
Published date: 2009 Jan
Plasma urate and progression of mild cognitive impairment.
Irizarry MC, Raman R, Schwarzschild MA, Becerra LM, Thomas RG, Peterson RC, Ascherio A, Aisen PS
Neuro-degenerative diseases 6 (1-2):23-8. PubMed PMID: 19066433
Published date: 2009
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.
Julien C, Tremblay C, Emond V, Lebbadi M, Salem N, Bennett DA, Calon F
Journal of neuropathology and experimental neurology 68 (1):48-58. PubMed PMID: 19104446
Published date: 2009 Jan
Changes in parahippocampal white matter integrity in amnestic mild cognitive impairment: a diffusion tensor imaging study.
Rogalski EJ, Murphy CM, deToledo-Morrell L, Shah RC, Moseley ME, Bammer R, Stebbins GT
Behavioural neurology 21 (1):51-61. PubMed PMID: 19847045
Published date: 2009
Developing a Measurement Strategy for Assessing Family Caregiver Skills: Conceptual Issues.
Farran CJ, McCann JJ, Fogg LG, Etkin CD
Alzheimer's care today 10 (3):129-139. PubMed PMID: 20179779
Published date: 2009
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R
Neuron 60 (6):988-1009. PubMed PMID: 19109907
Published date: 2008 Dec 26
Cognitive health in indigenous peoples.
Bennett DA
Neurology 71 (19):1466-7. PubMed PMID: 18799784
Published date: 2008 Nov 4
Cholinergic system during the progression of Alzheimer's disease: therapeutic implications.
Mufson EJ, Counts SE, Perez SE, Ginsberg SD
Expert review of neurotherapeutics 8 (11):1703-18. PubMed PMID: 18986241
Published date: 2008 Nov
Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci.
Lee JH, Cheng R, Graff-Radford N, Foroud T, Mayeux R
Archives of neurology 65 (11):1518-26. PubMed PMID: 19001172
Published date: 2008 Nov
Change in direct measures of physical performance among persons with Alzheimer's disease.
Hebert LE, Scherr PA, McCann JJ, Bienias JL, Evans DA
Aging & mental health 12 (6):729-34. PubMed PMID: 19023724
Published date: 2008 Nov
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS, Bennett DA, Trojanowski JQ, Arnold SE
The American journal of pathology 173 (5):1488-95. PubMed PMID: 18818379
Published date: 2008 Nov
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
Aisen PS, Schneider LS, Sano M, Diaz-Arrastia R, van Dyck CH, Weiner MF, Bottiglieri T, Jin S, Stokes KT, Thomas RG, Thal LJ
JAMA 300 (15):1774-83. PubMed PMID: 18854539
Published date: 2008 Oct 15
Rate of entorhinal and hippocampal atrophy in incipient and mild AD: relation to memory function.
Stoub TR, Rogalski EJ, Leurgans S, Bennett DA, Detoledo-Morrell L
Neurobiology of aging 31 (7):1089-98. PubMed PMID: 18809228
Published date: 2008 Sep 20
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, Beach TG, Mastroeni D, Grover A, Ravid R, Sando SB, Aasly JO, Heun R, Jessen F, Kölsch
Neurobiology of aging 31 (6):901-9. PubMed PMID: 18789830
Published date: 2008 Sep 11
Physical frailty in older persons is associated with Alzheimer disease pathology.
Buchman AS, Schneider JA, Leurgans S, Bennett DA
Neurology 71 (7):499-504. PubMed PMID: 18695161
Published date: 2008 Aug 12
Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trials.
Karlawish J, Kim SY, Knopman D, van Dyck CH, James BD, Marson D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 16 (7):568-74. PubMed PMID: 18556397
Published date: 2008 Jul
Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology.
Arvanitakis Z, Grodstein F, Bienias JL, Schneider JA, Wilson RS, Kelly JF, Evans DA, Bennett DA
Neurology 70 (23):2219-25. PubMed PMID: 18519870
Published date: 2008 Jun 3
Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?
Counts SE, Perez SE, Mufson EJ
Cellular and molecular life sciences : CMLS 65 (12):1842-53. PubMed PMID: 18500641
Published date: 2008 Jun
Statins, incident Alzheimer disease, change in cognitive function, and neuropathology.
Arvanitakis Z, Schneider JA, Wilson RS, Bienias JL, Kelly JF, Evans DA, Bennett DA
Neurology 70 (19 Pt 2):1795-802. PubMed PMID: 18199831
Published date: 2008 May 6
Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease.
Zhu H, Taylor JW, Bennett DA, Younkin SG, Estus S
Neurobiology of aging 29 (5):793-4. PubMed PMID: 17175070
Published date: 2008 May
A lifestyle physical activity intervention for caregivers of persons with Alzheimer's disease.
Farran CJ, Staffileno BA, Gilley DW, McCann JJ, Yan Li, Castro CM, King AC
American journal of Alzheimer's disease and other dementias 23 (2):132-42. PubMed PMID: 18174315
Published date: 2008 Apr-May
Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.
Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, Estus S
Human molecular genetics 17 (7):929-35. PubMed PMID: 18065781
Published date: 2008 Apr 1
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE
Nature neuroscience 11 (4):476-87. PubMed PMID: 18344994
Published date: 2008 Apr
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE
Nature neuroscience 11 (4):476-87. PubMed PMID: 18344994
Published date: 2008 Apr
Change in depressive symptoms during the prodromal phase of Alzheimer disease.
Wilson RS, Arnold SE, Beck TL, Bienias JL, Bennett DA
Archives of general psychiatry 65 (4):439-45. PubMed PMID: 18391132
Published date: 2008 Apr
The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollment.
Karlawish J, Kim SY, Knopman D, van Dyck CH, James BD, Marson D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 16 (3):240-7. PubMed PMID: 18310554
Published date: 2008 Mar
Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scores.
Kelly JF, Bienias JL, Shah A, Meeke KA, Schneider JA, Soriano E, Bennett DA
Current Alzheimer research 5 (1):45-51. PubMed PMID: 18288931
Published date: 2008 Feb
Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology.
Wang DS, Uchikado H, Bennett DA, Schneider JA, Mufson EJ, Wu J, Dickson DW
Journal of Alzheimer's disease : JAD 13 (1):53-66. PubMed PMID: 18334757
Published date: 2008 Feb
fMRI activation changes during successful episodic memory encoding and recognition in amnestic mild cognitive impairment relative to cognitively healthy older adults.
Trivedi MA, Murphy CM, Goetz C, Shah RC, Gabrieli JD, Whitfield-Gabrieli S, Turner DA, Stebbins GT
Dementia and geriatric cognitive disorders 26 (2):123-37. PubMed PMID: 18663302
Published date: 2008
Transcriptome-wide assessment of human brain and lymphocyte senescence.
Hong MG, Myers AJ, Magnusson PK, Prince JA
PloS one 3 (8):e3024. PubMed PMID: 18714388
Published date: 2008
Use of home-based formal services by adult day care clients with Alzheimer's disease.
Skarupski KA, McCann JJ, Bienias JL, Wolinsky FD, Aggarwal NT, Evans DA
Home health care services quarterly 27 (3):217-39. PubMed PMID: 19042238
Published date: 2008
Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Neuro-degenerative diseases 5 (3-4):228-31. PubMed PMID: 18322398
Published date: 2008
Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Neuro-degenerative diseases 5 (3-4):228-31. PubMed PMID: 18322398
Published date: 2008
Plaque complement activation and cognitive loss in Alzheimer's disease.
Loeffler DA, Camp DM, Bennett DA
Journal of neuroinflammation. PubMed PMID: 18334032
Published date: 2008
Mixed brain pathologies account for most dementia cases in community-dwelling older persons.
Schneider JA, Arvanitakis Z, Bang W, Bennett DA
Neurology 69 (24):2197-204. PubMed PMID: 17568013
Published date: 2007 Dec 11
Efficacy of behavioral interventions for dementia caregivers.
Farran CJ, Gilley DW, McCann JJ, Bienias JL, Lindeman DA, Evans DA
Western journal of nursing research 29 (8):944-60. PubMed PMID: 17596639
Published date: 2007 Dec
Neuronal LR11/sorLA expression is reduced in mild cognitive impairment.
Sager KL, Wuu J, Leurgans SE, Rees HD, Gearing M, Mufson EJ, Levey AI, Lah JJ
Annals of neurology 62 (6):640-7. PubMed PMID: 17721864
Published date: 2007 Dec
Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease.
Tremblay C, Pilote M, Phivilay A, Emond V, Bennett DA, Calon F
Journal of Alzheimer's disease : JAD 12 (4):377-90. PubMed PMID: 18198424
Published date: 2007 Dec
Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.
Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, Mufson EJ
Archives of neurology 64 (12):1771-6. PubMed PMID: 18071042
Published date: 2007 Dec
Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.
Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, Mufson EJ
Archives of neurology 64 (12):1771-6. PubMed PMID: 18071042
Published date: 2007 Dec
Mild cognitive impairment.
Aggarwal NT
Panminerva medica 49 (4):183-9. PubMed PMID: 18091670
Published date: 2007 Dec
A survey of genetic human cortical gene expression.
Myers AJ, Gibbs JR, Webster JA, Rohrer K, Zhao A, Marlowe L, Kaleem M, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Holmans P, Heward CB, Reiman EM, Stephan D, Hardy J
Nature genetics 39 (12):1494-9. PubMed PMID: 17982457
Published date: 2007 Dec
Paradoxical upregulation of glutamatergic presynaptic boutons during mild cognitive impairment.
Bell KF, Bennett DA, Cuello AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 27 (40):10810-7. PubMed PMID: 17913914
Published date: 2007 Oct 3
Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment.
Wilson RS, Schneider JA, Arnold SE, Bienias JL, Bennett DA
Archives of general psychiatry 64 (10):1204-12. PubMed PMID: 17909133
Published date: 2007 Oct
Repetition priming in aging and Alzheimer's disease: an integrative review and future directions.
Fleischman DA
Cortex; a journal devoted to the study of the nervous system and behavior 43 (7):889-97. PubMed PMID: 17941347
Published date: 2007 Oct
Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer disease.
Ikonomovic MD, Abrahamson EE, Isanski BA, Wuu J, Mufson EJ, DeKosky ST
Archives of neurology 64 (9):1312-7. PubMed PMID: 17846271
Published date: 2007 Sep
Estimation of the mediation effect with a binary mediator.
Li Y, Schneider JA, Bennett DA
Statistics in medicine 26 (18):3398-414. PubMed PMID: 17066450
Published date: 2007 Aug 15
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Man
Acta neuropathologica 114 (1):5-22. PubMed PMID: 17579875
Published date: 2007 Jul
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, Goate AM, Morris JC, Mishra M, Kwong LK, Stieber A, Xu Y, Forman MS, Troj
The American journal of pathology 171 (1):227-40. PubMed PMID: 17591968
Published date: 2007 Jul
Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons.
Schneider JA, Boyle PA, Arvanitakis Z, Bienias JL, Bennett DA
Annals of neurology 62 (1):59-66. PubMed PMID: 17503514
Published date: 2007 Jul
Chronic distress and incidence of mild cognitive impairment.
Wilson RS, Schneider JA, Boyle PA, Arnold SE, Tang Y, Bennett DA
Neurology 68 (24):2085-92. PubMed PMID: 17562829
Published date: 2007 Jun 12
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A
Neuron 54 (5):713-20. PubMed PMID: 17553421
Published date: 2007 Jun 7
Nursing home placement, day care use, and cognitive decline in Alzheimer's disease.
Wilson RS, McCann JJ, Li Y, Aggarwal NT, Gilley DW, Evans DA
The American journal of psychiatry 164 (6):910-5. PubMed PMID: 17541050
Published date: 2007 Jun
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.
Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ
Neurology 68 (18):1501-8. PubMed PMID: 17470753
Published date: 2007 May 1
Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment.
Assaraf MI, Diaz Z, Liberman A, Miller WH, Arvanitakis Z, Li Y, Bennett DA, Schipper HM
Journal of neuropathology and experimental neurology 66 (5):389-98. PubMed PMID: 17483696
Published date: 2007 May
Quetiapine for agitation or psychosis in patients with dementia and parkinsonism.
Kurlan R, Cummings J, Raman R, Thal L
Neurology 68 (17):1356-63. PubMed PMID: 17452579
Published date: 2007 Apr 24
Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.
Berger Z, Roder H, Hanna A, Carlson A, Rangachari V, Yue M, Wszolek Z, Ashe K, Knight J, Dickson D, Andorfer C, Rosenberry TL, Lewis J, Hutton M, Janus C
The Journal of neuroscience : the official journal of the Society for Neuroscience 27 (14):3650-62. PubMed PMID: 17409229
Published date: 2007 Apr 4
Activation of caspase-6 in aging and mild cognitive impairment.
Albrecht S, Bourdeau M, Bennett D, Mufson EJ, Bhattacharjee M, LeBlanc AC
The American journal of pathology 170 (4):1200-9. PubMed PMID: 17392160
Published date: 2007 Apr
Cortical biochemistry in MCI and Alzheimer disease: lack of correlation with clinical diagnosis.
Forman MS, Mufson EJ, Leurgans S, Pratico D, Joyce S, Leight S, Lee VM, Trojanowski JQ
Neurology 68 (10):757-63. PubMed PMID: 17339583
Published date: 2007 Mar 6
The significance of Pin1 in the development of Alzheimer's disease.
Wang S, Simon BP, Bennett DA, Schneider JA, Malter JS, Wang DS
Journal of Alzheimer's disease : JAD 11 (1):13-23. PubMed PMID: 17361031
Published date: 2007 Mar
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.
Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, Forman MS, Van Deerlin V, de Silva R, Hardy J
Neurobiology of disease 25 (3):561-70. PubMed PMID: 17174556
Published date: 2007 Mar
Confounding in the Estimation of Mediation Effects.
Li Y, Bienias JL, Bennett DA
Computational statistics & data analysis 51 (6):3173-3186. PubMed PMID: 17940582
Published date: 2007 Mar 1
Vascular dementia: emerging trends.
Aggarwal NT, Decarli C
Seminars in neurology 27 (1):66-77. PubMed PMID: 17226743
Published date: 2007 Feb
Chronic distress, age-related neuropathology, and late-life dementia.
Wilson RS, Arnold SE, Schneider JA, Li Y, Bennett DA
Psychosomatic medicine 69 (1):47-53. PubMed PMID: 17244848
Published date: 2007 Jan
Grip strength and the risk of incident Alzheimer's disease.
Buchman AS, Wilson RS, Boyle PA, Bienias JL, Bennett DA
Neuroepidemiology 29 (1-2):66-73. PubMed PMID: 17925596
Published date: 2007
Editorial comment on 'Prevalence of dementia in the United States: the aging, demographics, and memory study' by Plassman et al.
Bennett DA
Neuroepidemiology 29 (1-2):133-5. PubMed PMID: 17975327
Published date: 2007
Body mass index in older persons is associated with Alzheimer disease pathology.
Buchman AS, Schneider JA, Wilson RS, Bienias JL, Bennett DA
Neurology 67 (11):1949-54. PubMed PMID: 17159099
Published date: 2006 Dec 12
Diabetes is related to cerebral infarction but not to AD pathology in older persons.
Arvanitakis Z, Schneider JA, Wilson RS, Li Y, Arnold SE, Wang Z, Bennett DA
Neurology 67 (11):1960-5. PubMed PMID: 17159101
Published date: 2006 Dec 12
Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease.
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Bennett DA
Archives of neurology 63 (12):1763-9. PubMed PMID: 17172617
Published date: 2006 Dec
Association of daytime napping and Parkinsonian signs in Alzheimer's disease.
Park M, Comella CL, Leurgans SE, Fan W, Wilson RS, Bennett DA
Sleep medicine 7 (8):614-8. PubMed PMID: 17023213
Published date: 2006 Dec
Cognitive decline in old age: separating retest effects from the effects of growing older.
Wilson RS, Li Y, Bienias JL, Bennett DA
Psychology and aging 21 (4):774-89. PubMed PMID: 17201497
Published date: 2006 Dec
The amyloid pathology progresses in a neurotransmitter-specific manner.
Bell KF, Ducatenzeiler A, Ribeiro-da-Silva A, Duff K, Bennett DA, Cuello AC
Neurobiology of aging 27 (11):1644-57. PubMed PMID: 16271419
Published date: 2006 Nov
ADCS Prevention Instrument Project: overview and initial results.
Ferris SH, Aisen PS, Cummings J, Galasko D, Salmon DP, Schneider L, Sano M, Whitehouse PJ, Edland S, Thal LJ
Alzheimer disease and associated disorders 20 (4 Suppl 3):S109-23. PubMed PMID: 17135805
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: development of a brief verbal memory test for primary prevention clinical trials.
Salmon DP, Cummings JL, Jin S, Sano M, Sperling RA, Zamrini E, Petersen RC, Edland SD, Thal LJ, Ferris SH
Alzheimer disease and associated disorders 20 (4 Suppl 3):S139-46. PubMed PMID: 17135807
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: behavioral measures in primary prevention trials.
Cummings JL, Raman R, Ernstrom K, Salmon D, Ferris SH
Alzheimer disease and associated disorders 20 (4 Suppl 3):S147-51. PubMed PMID: 17135808
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: assessment of instrumental activities of daily living for community-dwelling elderly individuals in dementia prevention clinical trials.
Galasko D, Bennett DA, Sano M, Marson D, Kaye J, Edland SD
Alzheimer disease and associated disorders 20 (4 Suppl 3):S152-69. PubMed PMID: 17135809
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: the Mail-In Cognitive Function Screening Instrument (MCFSI).
Walsh SP, Raman R, Jones KB, Aisen PS
Alzheimer disease and associated disorders 20 (4 Suppl 3):S170-8. PubMed PMID: 17135810
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: quality of life assessment (QOL).
Patterson MB, Whitehouse PJ, Edland SD, Sami SA, Sano M, Smyth K, Weiner MF
Alzheimer disease and associated disorders 20 (4 Suppl 3):S179-90. PubMed PMID: 17135811
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: pharmacoeconomics: assessing health-related resource use among healthy elderly.
Sano M, Zhu CW, Whitehouse PJ, Edland S, Jin S, Ernstrom K, Thomas RG, Thal LJ, Ferris SH
Alzheimer disease and associated disorders 20 (4 Suppl 3):S191-202. PubMed PMID: 17135812
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: pilot testing of a book club as a psychosocial intervention and recruitment and retention strategy.
Whitehouse PJ, Rajcan JL, Sami SA, Patterson MB, Smyth KA, Edland SD, George DR
Alzheimer disease and associated disorders 20 (4 Suppl 3):S203-8. PubMed PMID: 17135813
Published date: 2006 Oct-Dec
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.
Scheff SW, Price DA, Schmitt FA, Mufson EJ
Neurobiology of aging 27 (10):1372-84. PubMed PMID: 16289476
Published date: 2006 Oct
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.
Scheff SW, Price DA, Schmitt FA, Mufson EJ
Neurobiology of aging 27 (10):1372-84. PubMed PMID: 16289476
Published date: 2006 Oct
The relation of lifetime cognitive activity and lifetime access to resources to late-life cognitive function in older African Americans.
Barnes LL, Wilson RS, de Leon CF, Bennett DA
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition 13 (3-4):516-28. PubMed PMID: 16887787
Published date: 2006 Sep-Dec
Blood pressure and lower limb function in older persons.
Shah RC, Wilson RS, Bienias JL, Arvanitakis Z, Evans DA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 61 (8):839-43. PubMed PMID: 16912102
Published date: 2006 Aug
Early involvement of small inhibitory cortical interneurons in Alzheimer's disease.
Koliatsos VE, Kecojevic A, Troncoso JC, Gastard MC, Bennett DA, Schneider JA
Acta neuropathologica 112 (2):147-62. PubMed PMID: 16758165
Published date: 2006 Aug
Reno-cerebrovascular disease? The incognito kidney in cognition and stroke.
Monk RD, Bennett DA
Neurology 67 (2):196-8. PubMed PMID: 16864806
Published date: 2006 Jul 25
Diabetes mellitus, dementia, and cognitive function in older persons.
Arvanitakis Z, Wilson RS, Bennett DA
The journal of nutrition, health & aging 10 (4):287-91. PubMed PMID: 16886098
Published date: 2006 Jul-Aug
Postmortem indices linking risk factors to cognition: results from the Religious Order Study and the Memory and Aging Project.
Bennett DA
Alzheimer disease and associated disorders 20 (3 Suppl 2):S63-8. PubMed PMID: 16917198
Published date: 2006 Jul-Sep
Single cell gene expression profiling in Alzheimer's disease.
Ginsberg SD, Che S, Counts SE, Mufson EJ
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 3 (3):302-18. PubMed PMID: 16815214
Published date: 2006 Jul
Personality and incident disability in older persons.
Krueger KR, Wilson RS, Shah RC, Tang Y, Bennett DA
Age and ageing 35 (4):428-33. PubMed PMID: 16788082
Published date: 2006 Jul
Neuropathology of older persons without cognitive impairment from two community-based studies.
Bennett DA, Schneider JA, Arvanitakis Z, Kelly JF, Aggarwal NT, Shah RC, Wilson RS
Neurology 66 (12):1837-44. PubMed PMID: 16801647
Published date: 2006 Jun 27
Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer's disease.
Stoub TR, deToledo-Morrell L, Stebbins GT, Leurgans S, Bennett DA, Shah RC
Proceedings of the National Academy of Sciences of the United States of America 103 (26):10041-5. PubMed PMID: 16785436
Published date: 2006 Jun 27
Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment.
Counts SE, Nadeem M, Lad SP, Wuu J, Mufson EJ
Journal of neuropathology and experimental neurology 65 (6):592-601. PubMed PMID: 16783169
Published date: 2006 Jun
Secular trends in stroke incidence and survival, and the occurrence of dementia.
Bennett DA
Stroke 37 (5):1144-5. PubMed PMID: 16601209
Published date: 2006 May
Casein kinase-1 isoforms differentially associate with neurofibrillary and granulovacuolar degeneration lesions.
Kannanayakal TJ, Tao H, Vandre DD, Kuret J
Acta neuropathologica 111 (5):413-21. PubMed PMID: 16557393
Published date: 2006 May
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, Bennett DA, Leurgans S, Turner DA, Stebbins GT
Neurobiology of aging 27 (5):663-72. PubMed PMID: 16005548
Published date: 2006 May
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, Bennett DA, Leurgans S, Turner DA, Stebbins GT
Neurobiology of aging 27 (5):663-72. PubMed PMID: 16005548
Published date: 2006 May
Cognitive decline and survival in Alzheimer's disease.
Wilson RS, Li Y, Aggarwal NT, McCann JJ, Gilley DW, Bienias JL, Barnes LL, Evans DA
International journal of geriatric psychiatry 21 (4):356-62. PubMed PMID: 16534773
Published date: 2006 Apr
Cognitive decline and survival in Alzheimer's disease.
Wilson RS, Li Y, Aggarwal NT, McCann JJ, Gilley DW, Bienias JL, Barnes LL, Evans DA
International journal of geriatric psychiatry 21 (4):356-62. PubMed PMID: 16534773
Published date: 2006 Apr
Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease.
Ginsberg SD, Che S, Wuu J, Counts SE, Mufson EJ
Journal of neurochemistry 97 (2):475-87. PubMed PMID: 16539663
Published date: 2006 Apr
Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease.
Ginsberg SD, Che S, Wuu J, Counts SE, Mufson EJ
Journal of neurochemistry 97 (2):475-87. PubMed PMID: 16539663
Published date: 2006 Apr
Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.
Counts SE, Chen EY, Che S, Ikonomovic MD, Wuu J, Ginsberg SD, Dekosky ST, Mufson EJ
Dementia and geriatric cognitive disorders 21 (4):205-14. PubMed PMID: 16410678
Published date: 2006
Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.
Counts SE, Chen EY, Che S, Ikonomovic MD, Wuu J, Ginsberg SD, Dekosky ST, Mufson EJ
Dementia and geriatric cognitive disorders 21 (4):205-14. PubMed PMID: 16410678
Published date: 2006
Cognitive leisure activities, but not watching TV, for future brain benefits.
Rundek T, Bennett DA
Neurology 66 (6):794-5. PubMed PMID: 16567692
Published date: 2006 Mar 28
Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Che S, Counts SE, Mufson EJ
Journal of neurochemistry 96 (5):1401-8. PubMed PMID: 16478530
Published date: 2006 Mar
Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Che S, Counts SE, Mufson EJ
Journal of neurochemistry 96 (5):1401-8. PubMed PMID: 16478530
Published date: 2006 Mar
Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus.
Dubelaar EJ, Mufson EJ, ter Meulen WG, Van Heerikhuize JJ, Verwer RW, Swaab DF
Journal of neuropathology and experimental neurology 65 (3):257-66. PubMed PMID: 16651887
Published date: 2006 Mar
Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus.
Dubelaar EJ, Mufson EJ, ter Meulen WG, Van Heerikhuize JJ, Verwer RW, Swaab DF
Journal of neuropathology and experimental neurology 65 (3):257-66. PubMed PMID: 16651887
Published date: 2006 Mar
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment.
Schipper HM, Bennett DA, Liberman A, Bienias JL, Schneider JA, Kelly J, Arvanitakis Z
Neurobiology of aging 27 (2):252-61. PubMed PMID: 16399210
Published date: 2006 Feb
Hallucinations, cognitive decline, and death in Alzheimer's disease.
Wilson RS, Tang Y, Aggarwal NT, Gilley DW, McCann JJ, Bienias JL, Evans DA
Neuroepidemiology 26 (2):68-75. PubMed PMID: 16352909
Published date: 2006
Nurr1 in Parkinson's disease and related disorders.
Chu Y, Le W, Kompoliti K, Jankovic J, Mufson EJ, Kordower JH
The Journal of comparative neurology 494 (3):495-514. PubMed PMID: 16320253
Published date: 2006 Jan 20
Substantia nigra tangles are related to gait impairment in older persons.
Schneider JA, Li JL, Li Y, Wilson RS, Kordower JH, Bennett DA
Annals of neurology 59 (1):166-73. PubMed PMID: 16374822
Published date: 2006 Jan
Relation of blood pressure to risk of incident Alzheimer's disease and change in global cognitive function in older persons.
Shah RC, Wilson RS, Bienias JL, Arvanitakis Z, Evans DA, Bennett DA
Neuroepidemiology 26 (1):30-6. PubMed PMID: 16254451
Published date: 2006
Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study.
Bennett DA, Schneider JA, Aggarwal NT, Arvanitakis Z, Shah RC, Kelly JF, Fox JH, Cochran EJ, Arends D, Treinkman AD, Wilson RS
Neuroepidemiology 27 (3):169-76. PubMed PMID: 17035694
Published date: 2006
Parkinsonian signs in subjects with mild cognitive impairment.
Boyle PA, Wilson RS, Aggarwal NT, Arvanitakis Z, Kelly J, Bienias JL, Bennett DA
Neurology 65 (12):1901-6. PubMed PMID: 16380610
Published date: 2005 Dec 27
Change in cognitive function in Alzheimer's disease in African-American and white persons.
Barnes LL, Wilson RS, Li Y, Gilley DW, Bennett DA, Evans DA
Neuroepidemiology 26 (1):16-22. PubMed PMID: 16254449
Published date: 2006
Racial differences in the progression of cognitive decline in Alzheimer disease.
Barnes LL, Wilson RS, Li Y, Aggarwal NT, Gilley DW, McCann JJ, Evans DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 13 (11):959-67. PubMed PMID: 16286439
Published date: 2005 Nov
Hallucinations and mortality in Alzheimer disease.
Wilson RS, Krueger KR, Kamenetsky JM, Tang Y, Gilley DW, Bennett DA, Evans DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 13 (11):984-90. PubMed PMID: 16286442
Published date: 2005 Nov
Mild cognitive impairment in different functional domains and incident Alzheimer's disease.
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Bennett DA
Journal of neurology, neurosurgery, and psychiatry 76 (11):1479-84. PubMed PMID: 16227534
Published date: 2005 Nov
Repetition priming and recognition memory in younger and older persons: temporal stability and performance.
Fleischman DA, Gabrieli JD, Wilson RS, Moro TT, Bennett DA
Neuropsychology 19 (6):750-9. PubMed PMID: 16351350
Published date: 2005 Nov
Neuroticism, extraversion, and mortality in a defined population of older persons.
Wilson RS, Krueger KR, Gu L, Bienias JL, Mendes de Leon CF, Evans DA
Psychosomatic medicine 67 (6):841-5. PubMed PMID: 16314587
Published date: 2005 Nov-Dec
High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures.
Lopez MF, Mikulskis A, Kuzdzal S, Bennett DA, Kelly J, Golenko E, DiCesare J, Denoyer E, Patton WF, Ediger R, Sapp L, Ziegert T, Lynch C, Kramer S, Whiteley GR, Wall MR, Mannion DP, Della Cioppa G, Rakitan JS, Wolfe GM
Clinical chemistry 51 (10):1946-54. PubMed PMID: 16081505
Published date: 2005 Oct
Socioeconomic characteristics of the community in childhood and cognition in old age.
Wilson RS, Scherr PA, Bienias JL, Mendes de Leon CF, Everson-Rose SA, Bennett DA, Evans DA
Experimental aging research 31 (4):393-407. PubMed PMID: 16147459
Published date: 2005 Oct-Dec
Change in body mass index and risk of incident Alzheimer disease.
Buchman AS, Wilson RS, Bienias JL, Shah RC, Evans DA, Bennett DA
Neurology 65 (6):892-7. PubMed PMID: 16186530
Published date: 2005 Sep 27
Education modifies the association of amyloid but not tangles with cognitive function.
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE
Neurology 65 (6):953-5. PubMed PMID: 16186546
Published date: 2005 Sep 27
Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people.
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Berry-Kravis E, Arnold SE
Journal of neurology, neurosurgery, and psychiatry 76 (9):1194-9. PubMed PMID: 16107349
Published date: 2005 Sep
Parkinsonian signs and cognitive function in old age.
Fleischman DA, Wilson RS, Bienias JL, Bennett DA
Journal of the International Neuropsychological Society : JINS 11 (5):591-7. PubMed PMID: 16212686
Published date: 2005 Sep
Implicit memory and Alzheimer's disease neuropathology.
Fleischman DA, Wilson RS, Gabrieli JD, Schneider JA, Bienias JL, Bennett DA
Brain : a journal of neurology 128 (Pt 9):2006-15. PubMed PMID: 15975947
Published date: 2005 Sep
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.
Newman J, Rissman RA, Sarsoza F, Kim RC, Dick M, Bennett DA, Cotman CW, Rohn TT, Head E
Acta neuropathologica 110 (2):135-44. PubMed PMID: 15986225
Published date: 2005 Aug
Relationship between Alzheimer's disease clinical stage and Gq/11 in subcellular fractions of frontal cortex.
Kelly JF, Storie K, Skamra C, Bienias J, Beck T, Bennett DA
Journal of neural transmission (Vienna, Austria : 1996) 112 (8):1049-56. PubMed PMID: 15583959
Published date: 2005 Aug
Detailed assessment of activities of daily living in moderate to severe Alzheimer's disease.
Galasko D, Schmitt F, Thomas R, Jin S, Bennett D
Journal of the International Neuropsychological Society : JINS 11 (4):446-53. PubMed PMID: 16209425
Published date: 2005 Jul
Risk of late-onset Alzheimer's disease associated with BDNF C270T polymorphism.
Olin D, MacMurray J, Comings DE
Neuroscience letters 381 (3):275-8. PubMed PMID: 15896483
Published date: 2005 Jun 24
Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease.
Zhu H, Gopalraj RK, Kelly JF, Bennett DA, Estus S
Neuroscience letters 381 (1-2):36-41. PubMed PMID: 15882786
Published date: 2005 Jun 10-17
Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.
Peng S, Wuu J, Mufson EJ, Fahnestock M
Journal of neurochemistry 93 (6):1412-21. PubMed PMID: 15935057
Published date: 2005 Jun
Sex differences in the clinical manifestations of Alzheimer disease pathology.
Barnes LL, Wilson RS, Bienias JL, Schneider JA, Evans DA, Bennett DA
Archives of general psychiatry 62 (6):685-91. PubMed PMID: 15939846
Published date: 2005 Jun
MRI predictors of risk of incident Alzheimer disease: a longitudinal study.
Stoub TR, Bulgakova M, Leurgans S, Bennett DA, Fleischman D, Turner DA, deToledo-Morrell L
Neurology 64 (9):1520-4. PubMed PMID: 15883311
Published date: 2005 May 10
The apolipoprotein E epsilon4 allele increases the odds of chronic cerebral infarction [corrected] detected at autopsy in older persons.
Schneider JA, Bienias JL, Wilson RS, Berry-Kravis E, Evans DA, Bennett DA
Stroke 36 (5):954-9. PubMed PMID: 15774818
Published date: 2005 May
Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease.
Bodner SM, Berrettini W, van Deerlin V, Bennett DA, Wilson RS, Trojanowski JQ, Arnold SE
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 134B (1):1-5. PubMed PMID: 15635706
Published date: 2005 Apr 5
The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease.
Counts SE, Mufson EJ
Journal of neuropathology and experimental neurology 64 (4):263-72. PubMed PMID: 15835262
Published date: 2005 Apr
Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions.
Bennett DA, Schneider JA, Bienias JL, Evans DA, Wilson RS
Neurology 64 (5):834-41. PubMed PMID: 15753419
Published date: 2005 Mar 8
Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease.
Ikonomovic MD, Mufson EJ, Wuu J, Bennett DA, DeKosky ST
Archives of neurology 62 (3):425-30. PubMed PMID: 15767507
Published date: 2005 Mar
Gender differences in upper extremity motor performance of older persons.
Buchman AS, Wilson RS, Bienias JL, Bennett DA
Geriatrics & gerontology international 5 (1):59-65. PubMed PMID: 25782068
Published date: 2005 Mar
Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease.
Georganopoulou DG, Chang L, Nam JM, Thaxton CS, Mufson EJ, Klein WL, Mirkin CA
Proceedings of the National Academy of Sciences of the United States of America 102 (7):2273-6. PubMed PMID: 15695586
Published date: 2005 Feb 15
The apolipoprotein E epsilon4 allele and incident Alzheimer's disease in persons with mild cognitive impairment.
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Berry-Kravis E, Bennett DA
Neurocase 11 (1):3-7. PubMed PMID: 15804918
Published date: 2005 Feb
Proneness to psychological distress and risk of Alzheimer disease in a biracial community.
Wilson RS, Barnes LL, Bennett DA, Li Y, Bienias JL, Mendes de Leon CF, Evans DA
Neurology 64 (2):380-2. PubMed PMID: 15668449
Published date: 2005 Jan 25
Immunization therapy for Alzheimer disease?
Bennett DA, Holtzman DM
Neurology 64 (1):10-2. PubMed PMID: 15642896
Published date: 2005 Jan 11
Genetic association of low density lipoprotein receptor and Alzheimer's disease.
Gopalraj RK, Zhu H, Kelly JF, Mendiondo M, Pulliam JF, Bennett DA, Estus S
Neurobiology of aging 26 (1):1-7. PubMed PMID: 15585340
Published date: 2005 Jan
Assessment of cognitive decline in old age with brief tests amenable to telephone administration.
Wilson RS, Bennett DA
Neuroepidemiology 25 (1):19-25. PubMed PMID: 15855801
Published date: 2005
A longitudinal study of implicit and explicit memory in old persons.
Fleischman DA, Wilson RS, Gabrieli JD, Bienias JL, Bennett DA
Psychology and aging 19 (4):617-25. PubMed PMID: 15584787
Published date: 2004 Dec
Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.
Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ
Annals of neurology 56 (4):520-31. PubMed PMID: 15455399
Published date: 2004 Oct
MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD.
deToledo-Morrell L, Stoub TR, Bulgakova M, Wilson RS, Bennett DA, Leurgans S, Wuu J, Turner DA
Neurobiology of aging 25 (9):1197-203. PubMed PMID: 15312965
Published date: 2004 Oct
Diabetes mellitus and progression of rigidity and gait disturbance in older persons.
Arvanitakis Z, Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA
Neurology 63 (6):996-1001. PubMed PMID: 15452289
Published date: 2004 Sep 28
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.
Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 24 (36):7895-902. PubMed PMID: 15356202
Published date: 2004 Sep 8
Subregional analysis of GABA(A) receptor subunit mRNAs in the hippocampus of older persons with and without cognitive impairment.
Rissman RA, Bennett DA, Armstrong DM
Journal of chemical neuroanatomy 28 (1-2):17-25. PubMed PMID: 15363487
Published date: 2004 Sep
A longitudinal study of parkinsonism and disability in a community population of older people.
Murray AM, Bennett DA, Mendes de Leon CF, Beckett LA, Evans DA
The journals of gerontology. Series A, Biological sciences and medical sciences 59 (8):864-70. PubMed PMID: 15345740
Published date: 2004 Aug
Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease.
Peng S, Wuu J, Mufson EJ, Fahnestock M
Journal of neuropathology and experimental neurology 63 (6):641-9. PubMed PMID: 15217092
Published date: 2004 Jun
Personality and mortality in old age.
Wilson RS, Mendes de Leon CF, Bienias JL, Evans DA, Bennett DA
The journals of gerontology. Series B, Psychological sciences and social sciences 59 (3):P110-6. PubMed PMID: 15118013
Published date: 2004 May
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function.
Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA
Archives of neurology 61 (5):661-6. PubMed PMID: 15148141
Published date: 2004 May
Caring for self while caring for others: the two-track life of coping with Alzheimer's disease.
Farran CJ, Loukissa DA, Lindeman DA, McCann JJ, Bienias JL
Journal of gerontological nursing 30 (5):38-46. PubMed PMID: 15152743
Published date: 2004 May
Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology.
Schneider JA, Wilson RS, Bienias JL, Evans DA, Bennett DA
Neurology 62 (7):1148-55. PubMed PMID: 15079015
Published date: 2004 Apr 13
Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older persons.
Bennett DA, Wilson RS, Schneider JA, Bienias JL, Arnold SE
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 12 (2):211-9. PubMed PMID: 15010350
Published date: 2004 Mar-Apr
Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function.
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE
Archives of neurology 61 (3):378-84. PubMed PMID: 15023815
Published date: 2004 Mar
Mild cognitive impairment.
Bennett DA
Clinics in geriatric medicine 20 (1):15-25. PubMed PMID: 15062484
Published date: 2004 Feb
Premorbid proneness to distress and episodic memory impairment in Alzheimer's disease.
Wilson RS, Fleischman DA, Myers RA, Bennett DA, Bienias JL, Gilley DW, Evans DA
Journal of neurology, neurosurgery, and psychiatry 75 (2):191-5. PubMed PMID: 14742585
Published date: 2004 Feb
Depressive symptoms and cognitive decline in a community population of older persons.
Wilson RS, Mendes De Leon CF, Bennett DA, Bienias JL, Evans DA
Journal of neurology, neurosurgery, and psychiatry 75 (1):126-9. PubMed PMID: 14707321
Published date: 2004 Jan
Proneness to psychological distress is associated with risk of Alzheimer's disease.
Wilson RS, Evans DA, Bienias JL, Mendes de Leon CF, Schneider JA, Bennett DA
Neurology 61 (11):1479-85. PubMed PMID: 14663028
Published date: 2003 Dec 9
Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.
Mufson EJ, Ginsberg SD, Ikonomovic MD, DeKosky ST
Journal of chemical neuroanatomy 26 (4):233-42. PubMed PMID: 14729126
Published date: 2003 Dec
Rate of cognitive decline and mortality in Alzheimer's disease.
Hui JS, Wilson RS, Bennett DA, Bienias JL, Gilley DW, Evans DA
Neurology 61 (10):1356-61. PubMed PMID: 14638955
Published date: 2003 Nov 25
Negative affect and mortality in older persons.
Wilson RS, Bienias JL, Mendes de Leon CF, Evans DA, Bennett DA
American journal of epidemiology 158 (9):827-35. PubMed PMID: 14585760
Published date: 2003 Nov 1
Depressive symptoms, clinical AD, and cortical plaques and tangles in older persons.
Wilson RS, Schneider JA, Bienias JL, Arnold SE, Evans DA, Bennett DA
Neurology 61 (8):1102-7. PubMed PMID: 14581672
Published date: 2003 Oct 28
Alzheimer's disease caregiving information and skills. Part I: care recipient issues and concerns.
Farran CJ, Loukissa D, Perraud S, Paun O
Research in nursing & health 26 (5):366-75. PubMed PMID: 14579257
Published date: 2003 Oct
Cognitive activity and cognitive decline in a biracial community population.
Wilson RS, Bennett DA, Bienias JL, Mendes de Leon CF, Morris MC, Evans DA
Neurology 61 (6):812-6. PubMed PMID: 14504326
Published date: 2003 Sep 23
Assessment of lifetime participation in cognitively stimulating activities.
Wilson R, Barnes L, Bennett D
Journal of clinical and experimental neuropsychology 25 (5):634-42. PubMed PMID: 12815501
Published date: 2003 Aug
Alzheimer disease in the US population: prevalence estimates using the 2000 census.
Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA
Archives of neurology 60 (8):1119-22. PubMed PMID: 12925369
Published date: 2003 Aug
Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.
Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, DeKosky ST
Archives of neurology 60 (8):1143-8. PubMed PMID: 12925373
Published date: 2003 Aug
Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.
Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, DeKosky ST
Archives of neurology 60 (8):1143-8. PubMed PMID: 12925373
Published date: 2003 Aug
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease.
Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J
Archives of neurology 60 (7):940-6. PubMed PMID: 12873849
Published date: 2003 Jul
Education modifies the relation of AD pathology to level of cognitive function in older persons.
Bennett DA, Wilson RS, Schneider JA, Evans DA, Mendes de Leon CF, Arnold SE, Barnes LL, Bienias JL
Neurology 60 (12):1909-15. PubMed PMID: 12821732
Published date: 2003 Jun 24
Gender, cognitive decline, and risk of AD in older persons.
Barnes LL, Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA
Neurology 60 (11):1777-81. PubMed PMID: 12796530
Published date: 2003 Jun 10
Terminal decline in cognitive function.
Wilson RS, Beckett LA, Bienias JL, Evans DA, Bennett DA
Neurology 60 (11):1782-7. PubMed PMID: 12796531
Published date: 2003 Jun 10
Relation of cerebral infarctions to dementia and cognitive function in older persons.
Schneider JA, Wilson RS, Cochran EJ, Bienias JL, Arnold SE, Evans DA, Bennett DA
Neurology 60 (7):1082-8. PubMed PMID: 12682310
Published date: 2003 Apr 8
Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.
Yang Y, Mufson EJ, Herrup K
The Journal of neuroscience : the official journal of the Society for Neuroscience 23 (7):2557-63. PubMed PMID: 12684440
Published date: 2003 Apr 1
Parkinsonianlike signs and risk of incident Alzheimer disease in older persons.
Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA
Archives of neurology 60 (4):539-44. PubMed PMID: 12707067
Published date: 2003 Apr
Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology.
Ikonomovic MD, Mufson EJ, Wuu J, Cochran EJ, Bennett DA, DeKosky ST
Journal of Alzheimer's disease : JAD 5 (1):39-48. PubMed PMID: 12590165
Published date: 2003 Feb
Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease.
Bennett DA, Wilson RS, Schneider JA, Evans DA, Aggarwal NT, Arnold SE, Cochran EJ, Berry-Kravis E, Bienias JL
Neurology 60 (2):246-52. PubMed PMID: 12552039
Published date: 2003 Jan 28
The apolipoprotein E epsilon 2 allele and decline in episodic memory.
Wilson RS, Bienias JL, Berry-Kravis E, Evans DA, Bennett DA
Journal of neurology, neurosurgery, and psychiatry 73 (6):672-7. PubMed PMID: 12438469
Published date: 2002 Dec
Cerebrospinal fluid shunting for Alzheimer's disease?
Bennett DA, McDermott MP
Neurology 59 (8):1126-7. PubMed PMID: 12391336
Published date: 2002 Oct 22
Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.
Ghoshal N, García-Sierra F, Wuu J, Leurgans S, Bennett DA, Berry RW, Binder LI
Experimental neurology 177 (2):475-93. PubMed PMID: 12429193
Published date: 2002 Oct
Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.
Ghoshal N, García-Sierra F, Wuu J, Leurgans S, Bennett DA, Berry RW, Binder LI
Experimental neurology 177 (2):475-93. PubMed PMID: 12429193
Published date: 2002 Oct
Natural history of mild cognitive impairment in older persons.
Bennett DA, Wilson RS, Schneider JA, Evans DA, Beckett LA, Aggarwal NT, Barnes LL, Fox JH, Bach J
Neurology 59 (2):198-205. PubMed PMID: 12136057
Published date: 2002 Jul 23
The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period.
Wilson RS, Schneider JA, Barnes LL, Beckett LA, Aggarwal NT, Cochran EJ, Berry-Kravis E, Bach J, Fox JH, Evans DA, Bennett DA
Archives of neurology 59 (7):1154-60. PubMed PMID: 12117364
Published date: 2002 Jul
Progression of gait disorder and rigidity and risk of death in older persons.
Wilson RS, Schneider JA, Beckett LA, Evans DA, Bennett DA
Neurology 58 (12):1815-9. PubMed PMID: 12084882
Published date: 2002 Jun 25
Individual differences in rates of change in cognitive abilities of older persons.
Wilson RS, Beckett LA, Barnes LL, Schneider JA, Bach J, Evans DA, Bennett DA
Psychology and aging 17 (2):179-93. PubMed PMID: 12061405
Published date: 2002 Jun
Association between blood pressure and cognitive function in a biracial community population of older persons.
Morris MC, Scherr PA, Hebert LE, Bennett DA, Wilson RS, Glynn RJ, Evans DA
Neuroepidemiology 21 (3):123-30. PubMed PMID: 12006775
Published date: 2002 May-Jun
Participation in cognitively stimulating activities and risk of incident Alzheimer disease.
Wilson RS, Mendes De Leon CF, Barnes LL, Schneider JA, Bienias JL, Evans DA, Bennett DA
JAMA 287 (6):742-8. PubMed PMID: 11851541
Published date: 2002 Feb 13
Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
Mufson EJ, Ma SY, Dills J, Cochran EJ, Leurgans S, Wuu J, Bennett DA, Jaffar S, Gilmor ML, Levey AI, Kordower JH
The Journal of comparative neurology 443 (2):136-53. PubMed PMID: 11793352
Published date: 2002 Feb 4
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.
DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, Cochran EJ, Kordower JH, Mufson EJ
Annals of neurology 51 (2):145-55. PubMed PMID: 11835370
Published date: 2002 Feb
Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease.
Mitchell TW, Mufson EJ, Schneider JA, Cochran EJ, Nissanov J, Han LY, Bienias JL, Lee VM, Trojanowski JQ, Bennett DA, Arnold SE
Annals of neurology 51 (2):182-9. PubMed PMID: 11835374
Published date: 2002 Feb
Impaired production priming and intact identification priming in Alzheimer's disease.
Fleischman DA, Monti LA, Dwornik LM, Moro TT, Bennett DA, Gabrieli JD
Journal of the International Neuropsychological Society : JINS 7 (7):785-94. PubMed PMID: 11771621
Published date: 2001 Nov
Annual incidence of Alzheimer disease in the United States projected to the years 2000 through 2050.
Hebert LE, Beckett LA, Scherr PA, Evans DA
Alzheimer disease and associated disorders 15 (4):169-73. PubMed PMID: 11723367
Published date: 2001 Oct-Dec
MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease.
Dickerson BC, Goncharova I, Sullivan MP, Forchetti C, Wilson RS, Bennett DA, Beckett LA, deToledo-Morrell L
Neurobiology of aging 22 (5):747-54. PubMed PMID: 11705634
Published date: 2001 Sep-Oct
Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease.
Chu Y, Cochran EJ, Bennett DA, Mufson EJ, Kordower JH
The Journal of comparative neurology 437 (3):296-307. PubMed PMID: 11494257
Published date: 2001 Aug 27
Type 2 diabetes and cognitive function in community-dwelling elderly women.
Grodstein F, Chen J, Wilson RS, Manson JE
Diabetes care 24 (6):1060-5. PubMed PMID: 11375371
Published date: 2001 Jun
Is the risk of developing Alzheimer's disease greater for women than for men?
Hebert LE, Scherr PA, McCann JJ, Beckett LA, Evans DA
American journal of epidemiology 153 (2):132-6. PubMed PMID: 11159157
Published date: 2001 Jan 15
Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease.
Counts SE, Perez SE, Kahl U, Bartfai T, Bowser RP, Deecher DC, Mash DC, Crawley JN, Mufson EJ
CNS drug reviews 7 (4):445-70. PubMed PMID: 11830760
Published date: 2001 Winter
Decline of language among women and men with Alzheimer's disease.
Hebert LE, Wilson RS, Gilley DW, Beckett LA, Scherr PA, Bennett DA, Evans DA
The journals of gerontology. Series B, Psychological sciences and social sciences 55 (6):P354-60. PubMed PMID: 11078105
Published date: 2000 Nov
Part I. Epidemiology and public health impact of Alzheimer's disease.
Bennett DA
Disease-a-month : DM 46 (10):657-65. PubMed PMID: 11078008
Published date: 2000 Oct
Part II. Clinical diagnosis and course of Alzheimer's disease.
Bennett DA
Disease-a-month : DM 46 (10):666-86. PubMed PMID: 11078009
Published date: 2000 Oct
From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy.
de Toledo-Morrell L, Goncharova I, Dickerson B, Wilson RS, Bennett DA
Annals of the New York Academy of Sciences 911 (6):240-53. PubMed PMID: 10911878
Published date: 2000 Jun
The cross-sectional association between blood pressure and Alzheimer's disease in a biracial community population of older persons.
Morris MC, Scherr PA, Hebert LE, Bennett DA, Wilson RS, Glynn RJ, Evans DA
The journals of gerontology. Series A, Biological sciences and medical sciences 55 (3):M130-6. PubMed PMID: 10795724
Published date: 2000 Mar
Diabetes and change in cognitive function.
Bennett DA
Archives of internal medicine 160 (2):141-3. PubMed PMID: 10647749
Published date: 2000 Jan 24
A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease.
Ghoshal N, Smiley JF, DeMaggio AJ, Hoekstra MF, Cochran EJ, Binder LI, Kuret J
The American journal of pathology 155 (4):1163-72. PubMed PMID: 10514399
Published date: 1999 Oct
Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA.
Melov S, Schneider JA, Coskun PE, Bennett DA, Wallace DC
Neurobiology of aging 20 (5):565-71. PubMed PMID: 10638530
Published date: 1999 Sep-Oct
Entorhinal cortex beta-amyloid load in individuals with mild cognitive impairment.
Mufson EJ, Chen EY, Cochran EJ, Beckett LA, Bennett DA, Kordower JH
Experimental neurology 158 (2):469-90. PubMed PMID: 10415154
Published date: 1999 Aug
Dimensionality of parkinsonian signs in aging and Alzheimer's disease.
Bennett DA, Shannon KM, Beckett LA, Wilson RS
The journals of gerontology. Series A, Biological sciences and medical sciences 54 (4):M191-6. PubMed PMID: 10219010
Published date: 1999 Apr
Word-stem completion priming in healthy aging and Alzheimer's disease: the effects of age, cognitive status, and encoding.
Fleischman DA, Gabrieli JD, Gilley DW, Hauser JD, Lange KL, Dwornik LM, Bennett DA, Wilson RS
Neuropsychology 13 (1):22-30. PubMed PMID: 10067772
Published date: 1999 Jan
Object decision priming in Alzheimer's disease.
Fleischman DA, Gabrieli JD, Reminger SL, Vaidya CJ, Bennett DA
Journal of the International Neuropsychological Society : JINS 4 (5):435-46. PubMed PMID: 9745233
Published date: 1998 Sep
Metric properties of nurses' ratings of parkinsonian signs with a modified Unified Parkinson's Disease Rating Scale.
Bennett DA, Shannon KM, Beckett LA, Goetz CG, Wilson RS
Neurology 49 (6):1580-7. PubMed PMID: 9409350
Published date: 1997 Dec
Alzheimer's disease: in vivo detection of differential vulnerability of brain regions.
Detoledo-Morrell L, Sullivan MP, Morrell F, Wilson RS, Bennett DA, Spencer S
Neurobiology of aging 18 (5):463-8. PubMed PMID: 9390771
Published date: 1997 Sep-Oct
Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
Levey AI, Heilman CJ, Lah JJ, Nash NR, Rees HD, Wakai M, Mirra SS, Rye DB, Nochlin D, Bird TD, Mufson EJ
Annals of neurology 41 (6):742-53. PubMed PMID: 9189035
Published date: 1997 Jun
Around the WORLD backward: an algorithm for scoring the MMSE WORLD item.
Beckett LA, Wilson RS, Bennett DA, Morris MC
Neurology 48 (6):1733-4. PubMed PMID: 9191800
Published date: 1997 Jun
Weight loss in people with Alzheimer's disease: a prospective population based analysis.
Cronin-Stubbs D, Beckett LA, Scherr PA, Field TS, Chown MJ, Pilgrim DM, Bennett DA, Evans DA
BMJ (Clinical research ed.) 314 (7075):178-9. PubMed PMID: 9022430
Published date: 1997 Jan 18
Word-stem completion priming for perceptually and conceptually encoded words in patients with Alzheimer's disease.
Fleischman DA, Gabrieli JD, Rinaldi JA, Reminger SL, Grinnell ER, Lange KL, Shapiro R
Neuropsychologia 35 (1):25-35. PubMed PMID: 8981374
Published date: 1997 Jan
Familial Creutzfeldt-Jakob disease with a five-repeat octapeptide insert mutation.
Cochran EJ, Bennett DA, Cervenkov L, Kenney K, Bernard B, Foster NL, Benson DF, Goldfarb LG, Brown P
Neurology 47 (3):727-33. PubMed PMID: 8797471
Published date: 1996 Sep
Reduced nicotinamide adenine dinucleotide phosphate-diaphorase/nitric oxide synthase profiles in the human hippocampal formation and perirhinal cortex.
Sobreviela T, Mufson EJ
The Journal of comparative neurology 358 (3):440-64. PubMed PMID: 7560297
Published date: 1995 Jul 31
Epidemiology of injury in people with Alzheimer's disease.
Oleske DM, Wilson RS, Bernard BA, Evans DA, Terman EW
Journal of the American Geriatrics Society 43 (7):741-6. PubMed PMID: 7602023
Published date: 1995 Jul
TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin.
Sobreviela T, Clary DO, Reichardt LF, Brandabur MM, Kordower JH, Mufson EJ
The Journal of comparative neurology 350 (4):587-611. PubMed PMID: 7890832
Published date: 1994 Dec 22
Cholinergic innervation in the human hippocampal formation including the entorhinal cortex.
De Lacalle S, Lim C, Sobreviela T, Mufson EJ, Hersh LB, Saper CB
The Journal of comparative neurology 345 (3):321-44. PubMed PMID: 7929905
Published date: 1994 Jul 15
White matter changes: neurobehavioral manifestations of Binswanger's disease and clinical correlates in Alzheimer's disease.
Bennett DA, Gilley DW, Lee S, Cochran EJ
Dementia (Basel, Switzerland) 5 (3-4):148-52. PubMed PMID: 8087170
Published date: 1994 May-Aug
Nerve growth factor-like immunoreactive profiles in the primate basal forebrain and hippocampal formation.
Mufson EJ, Conner JM, Varon S, Kordower JH
The Journal of comparative neurology 341 (4):507-19. PubMed PMID: 8201026
Published date: 1994 Mar 22
Pathological changes in frontal cortex from biopsy to autopsy in Alzheimer's disease.
Bennett DA, Cochran EJ, Saper CB, Leverenz JB, Gilley DW, Wilson RS
Neurobiology of aging 14 (6):589-96. PubMed PMID: 8295661
Published date: 1993 Nov-Dec
Clinical correlates of high signal lesions on magnetic resonance imaging in Alzheimer's disease.
Bennett DA, Gilley DW, Wilson RS, Huckman MS, Fox JH
Journal of neurology 239 (4):186-90. PubMed PMID: 1597684
Published date: 1992 Apr
Memory failure in binswanger's disease and alzheimer's disease.
Bernard BA, Wilson RS, Gilley DW, Bennett DA, Fox JH, Waters WF
The Clinical neuropsychologist 6 (2):230-240. PubMed PMID: 29022447
Published date: 1992 Apr
High-throughput digital quantification of Alzheimer disease pathology and associated infrastructure in large autopsy studies.
Kapasi A, Poirier J, Hedayat A, Scherlek A, Mondal S, Wu T, Gibbons J, Barnes LL, Bennett DA, Leurgans SE, Schneider JA
Journal of neuropathology and experimental neurology 82 (12):976-986. PubMed PMID: 37944065
Published date: 202 3 Nov 20

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