Variable Details
Cognition
- Random slope of global cognition (demographics)
- Random slope of episodic memory (demographics)
- Random slope of working memory (demographics)
- Random slope of semantic memory (demographics)
- Random slope of perceptual speed (demographics)
- Random slope of visuospatial ability/perceptual orientation (demographics)
- Random slope of global cognition (demographics + pathology)
- Random slope of episodic memory (demographics + pathology)
- Random slope of working memory (demographics + pathology)
- Random slope of semantic memory (demographics + pathology)
- Random slope of perceptual speed (demographics + pathology)
- Random slope of visuospatial ability/perceptual orientation (demog + pathology)
Available Studies
ROS, MAP, MARS, Clinical Core
Categories
Cognition
Random slope of global cognition (demographics + pathology)
Estimated slope for global cognition controlled for demographics and pathology
The random slope of global cognition (demographics + pathology) is the estimated person-specific rate of change in the global cognition variable over time, controlled for the following demographics and pathology. It comes from a linear mixed effects model with global cognition as the outcome.
Demographics:
- Age at death
- Sex
- Years of education
Pathology:
- Global AD pathology burden
- Amyloid beta
- PHF tau tangles
- Gross chronic cerebral infarctions
- Chronic microinfarctions
- Lewy body disease
- TDP-43
- Hippocampal sclerosis
- Cerebral amyloid angiopathy
- Cerebral atherosclerosis
- Arteriolosclerosis
Notes: Time in this model refers to years from date of death.
The listed reference describes the model adjusting for demographics.