Documentation
Overviews and Timelines
Cohort Study Designs
Substudies
Variables
Standard Dataset Variables
Omics
Dynamic Reports
Requests
PARDoS
Login / Create Account
Feedback
×
Feedback
Please create an account and log in to leave feedback.
Home
Documentation
Variables
Variable Index
Variable Index
Variable search by name
No variables found!
Combine using:
AND
OR
All categories and variables:
Include study cohorts:
ROS
MAP
MARS
Clinical Core
LATC
Currently filtering using:
All categories and variables
Category
Subcategory
Variable
Actigraphy
Actigraphy data
Average total daily activity
Actical activity measure - Average total daily activity (MAP only)
Average daily activity per active hour
Actical activity measure - Average activity per hour of activity (MAP only)
Average daily inactivity
Actical activity measure - Average percentage of day without activity (MAP only)
Affect and Personality
NEO
Neuroticism
Neuroticism from NEO Five-Factor Inventory - Sum of 12 items
Extraversion
Extraversion from NEO Five-Factor Inventory - Sum of 6 items
Openness
Openness from NEO Five-Factor Inventory - Sum of 12 items (ROS only)
Agreeableness
Agreeableness from NEO Five-Factor Inventory - Sum of 12 items (ROS only)
Conscientiousness
Conscientiousness from NEO Five-Factor Inventory - Sum of 12 items
Negative affect
Anger
Anger - Sum of 10 items
Anger-in
Tendency to internally experience anger - Sum of 8 items
Anger-out
Tendency to outwardly express anger - Sum of 8 items (ROS only)
Anxiety (10 items)
Level of anxiety - Sum of 10 items (ROS, MAP, LATC only)
Anxiety (20 items)
Level of anxiety - Sum of 20 items (ROS only)
Negative life events
Negative life events in the past year - Sum of 18 items (MAP only)
Negative social exchange
Frequency of negative social exchange in the past month - Average of 12 items (MAP only)
PANAS score
Positive and Negative Affect Schedule - Average of 10 items (MAP only)
Perceived stress
Perceived stress in past month - Average of 4 items
Childhood adversity
Total adverse experience
Childhood adversity: Total adverse experience - Sum of subscales
Emotional neglect
Childhood adversity subscale: Emotional neglect - Sum of 6 items
Financial need
Childhood adversity subscale: Financial need - Sum of 2 items
Parental intimidation
Childhood adversity subscale: Parental intimidation - Sum of 4 items
Parental violence
Childhood adversity subscale: Parental violence - Sum of 2 items
Family problems and separation
Childhood adversity subscale: Family problems and separation - Sum of 8 items
Temperament and Character Inventory
Novelty seeking
Novelty seeking scale - Sum of 40 items (MAP only)
Exploratory excitability
Novelty seeking subscale: Exploratory excitability - Sum of 11 items (MAP only)
Impulsiveness
Novelty seeking subscale: Impulsiveness - Sum of 10 items (MAP only)
Extravagance
Novelty seeking subscale: Extravagance - Sum of 10 items (MAP only)
Disorderliness
Novelty seeking subscale: Disorderliness - Sum of 9 items
Harm avoidance
Harm avoidance scale - Sum of 35 items
Anticipatory worry
Harm avoidance subscale: Anticipatory worry - Sum of 11 items
Fear of uncertainty
Harm avoidance subscale: Fear of uncertainty - Sum of 7 items
Shyness
Harm avoidance subscale: Shyness - Sum of 8 items
Fatigability
Harm avoidance subscale: Fatigability - Sum of 9 items
ApoE and TOMM40
ApoE
ApoE genotype
Apolipoprotein E genotype
TOMM40
TOMM40 genotype
Translocase of outer mitochondrial membrane 40 genotype
Blood Measures
Inflammatory markers
Age-related inflammation
Age-related inflammation
Ratio of good to bad inflammation
Ratio of good to bad inflammation
Vascular inflammation - 2 items
Vascular inflammation based on 2 inflammatory markers
Vascular inflammation - 3 items
Vascular inflammation based on 3 inflammatory markers
CRP level
Log transformed level of C-reactive protein
IL-1beta level
Log transformed level of interleukin-1beta
IL-1RA level
Log transformed level of interleukin-1 receptor agonist
IL-10 level
Log transformed level of interleukin-10
IL-6 level
Log transformed level of interleukin-6
IL-6R level
Log transformed level of interleukin-6 receptor
MMP9 level
Log transformed level of matrix metallopeptidase 9
TNF-alpha level
Log transformed level of tumor necrosis factor-alpha
VCAM level
Log transformed level of vascular cell adhesion molecule
Pathogens
CMV serostatus
Cytomegalovirus serostatus in serum
Gliadin serostatus
Gliadin serostatus in serum
HSV-1 serostatus
Herpes simplex virus type 1 serostatus in serum
Toxoplasma serostatus
Toxoplasma serostatus in serum
Toxoplasma serostatus (IU)
Toxoplasma serostatus in serum (international units)
Routine laboratory tests
Anemia
Anemia calculated from hemoglobin using WHO criteria
Blood urea nitrogen (BUN)
Blood urea nitrogen in blood samples
Calcium level
Calcium level in blood samples
Carbon dioxide level
Carbon dioxide level in blood samples
Chloride level
Chloride level in blood samples
Cholesterol/HDL ratio
Ratio of total cholesterol to HDL in blood samples
Creatinine level
Creatinine level in blood samples
Estimated glomerular filtration rate
Glomerular filtration rate based on Modified Diet in Renal Disease study
Fasting status
Fasting status at time of blood draw
Glucose level
Glucose level in blood samples
Hematocrit
Hematocrit in blood samples
Hemoglobin
Hemoglobin in blood samples
Hemoglobin A1c level
Hemoglobin A1c in blood samples
HDL cholesterol level
HDL cholesterol level in blood samples
LDL cholesterol level
LDL cholesterol level in blood samples
Mean corpuscular hemoglobin (MCH)
Mean corpuscular hemoglobin in blood samples
Mean corpuscular hemoglobin concentration (MCHC)
Mean corpuscular hemoglobin concentration in blood samples
Mean corpuscular volume (MCV)
Mean corpuscular volume in blood samples
Platelet count
Platelet count in blood samples
Potassium level
Potassium level in blood samples
RBC count
Red blood cell (RBC) count in blood samples
RBC distribution width
Red blood cell distribution width in blood samples
Sodium level
Sodium level in blood samples
TSH level
Thyroid-stimulating hormone level in blood samples
Total cholesterol level
Total cholesterol level in blood samples
Triglyceride level
Triglyceride level in blood samples
WBC count
White blood cell (WBC) count in blood samples
Brain Proteins
Presynaptic proteins (ELISA)
Complexin-I (inhibitory)
Complexin-I protein density - Average of 6 regions (MAP only)
Complexin-II (excitatory)
Complexin-II protein density - Average of 6 regions (MAP only)
SNAP-25
Synaptosomal-associated protein 25 (SNAP-25) density - Average of 6 regions (MAP only)
Synaptophysin
Synaptophysin protein density - Average of 6 regions (MAP only)
Syntaxin-1
Synatxin-1 protein density - Average of 6 regions (MAP only)
VAMP
Vesicle-associated membrane protein (VAMP) density - Average of 6 regions (MAP only)
Mean complexin density
Mean complexin density - Average of 6 regions (MAP only)
Mean SNARE protein density
Mean SNARE protein density - Average of 6 regions (MAP only)
Mean SNARE protein-protein interactions
Mean SNARE protein-protein interactions - Average of 6 regions (MAP only)
SRM proteomics
TMT proteomics
Clinical Diagnosis
Dementia
Clinical cognitive diagnosis summary
Clinical diagnosis of cognitive status (Alzheimer's dementia, other dementia, MCI, or no impairment)
Age at first Alzheimer's dementia dx
Age at cycle where first Alzheimer's dementia diagnosis was given
Final consensus diagnosis
Final consensus cognitive diagnosis
Clinical consensus diagnosis of cognitive status at time of death
Parkinson's disease
Clinical Parkinson's disease
Diagnosis of Parkinson's disease made by clinician based on clinical review
Stroke
Stroke diagnosis
Diagnosis of stroke made by clinician
Cognition
Global cognition
Global cognitive function
Global cognitive function - Average of 19 tests
Domains
Episodic memory
Episodic memory domain - Average of 7 tests
Working memory
Working memory domain - Average of 3 tests
Semantic memory
Semantic memory domain - Average of 3 tests
Perceptual speed
Perceptual speed domain - Average of 4 tests
Visuospatial ability/perceptual orientation
Visuospatial ability/perceptual orientation domain - Average of 2 tests
Test scores
Estimated MMSE
MMSE, or estimated MMSE score based on MoCA
Telephone cognitive test battery
Phone cog indicator
Indicator of cognitive testing over phone
Self-reported cognitive concerns
Memory trouble
Presence of memory complaints
Estimated slopes
Random slope of global cognition (demographics)
Estimated slope for global cognition controlled for demographics
Random slope of episodic memory (demographics)
Estimated slope for episodic memory controlled for demographics
Random slope of working memory (demographics)
Estimated slope for working memory controlled for demographics
Random slope of semantic memory (demographics)
Estimated slope for semantic memory controlled for demographics
Random slope of perceptual speed (demographics)
Estimated slope for perceptual speed controlled for demographics
Random slope of visuospatial ability/perceptual orientation (demographics)
Estimated slope for visuospatial ability/perceptual orientation controlled for demographics
Random slope of global cognition (demographics + pathology)
Estimated slope for global cognition controlled for demographics and pathology
Random slope of episodic memory (demographics + pathology)
Estimated slope for episodic memory controlled for demographics and pathology
Random slope of working memory (demographics + pathology)
Estimated slope for working memory controlled for demographics and pathology
Random slope of semantic memory (demographics + pathology)
Estimated slope for semantic memory controlled for demographics and pathology
Random slope of perceptual speed (demographics + pathology)
Estimated slope for perceptual speed controlled for demographics and pathology
Random slope of visuospatial ability/perceptual orientation (demog + pathology)
Estimated slope for visuospatial ability/perceptual orientation controlled for demographics and pathology
Cognitively-defined AD subgrouping
Cultural Experiences
Perceptions of Alzheimer's disease risk
Risk factor - genetics
Perception of genetics as an Alzheimer's disease risk factor (MARS only)
Risk factor - mental illness
Perception of mental illness as an Alzheimer's disease risk factor (MARS only)
Risk factor - stress
Perception of stress as an Alzheimer's disease risk factor (MARS only)
Risk factor - age
Perception of age as an Alzheimer's disease risk factor (MARS only)
Risk factor - God's will
Perception of God's will as an Alzheimer's disease risk factor (MARS only)
Risk factor - head injury
Perception of head injury as an Alzheimer's disease risk factor (MARS only)
Risk factor - toxin exposure
Perception of toxin exposure as an Alzheimer's disease risk factor (MARS only)
Risk factor - alcohol
Perception of alcohol as an Alzheimer's disease risk factor (MARS only)
Risk factor - smoking
Perception of smoking as an Alzheimer's disease risk factor (MARS only)
Decision Making and Behavioral Economics
Decision making ability
Financial decision making
Financial decision making ability - Sum of 6 items
Healthcare decision making
Healthcare decision making ability - Sum of 6 items
Decision making (Total)
Decision making ability, Total - Sum of 12 items
Scam susceptibility
Measure of susceptibility to scams - Average of 5 items
Fraud victimhood
Self-reported fraud victimhood
Decision making style
Risk tolerance
Willingness to take risks in general
Risk aversion
Risk aversion tendency coefficient
Temporal discounting - large stakes
Temporal discounting tendency for large stakes
Temporal discounting - small stakes
Temporal discounting tendency for small stakes
Literacy
Financial literacy
Financial literacy percentage
Health literacy
Health Literacy Percent
Literacy total
Total health and financial literacy percent
Confidence in domain-specific knowledge
Confidence: Healthcare knowledge
Self-reported confidence rating of healthcare knowledge - Average of 4 items
Confidence: Institutional knowledge
Self-reported confidence rating of institutional knowledge - Average of 9 items
Demographics
Sex
Sex
Education
Years of education
Race
Racial group
Spanish ethnicity
Spanish/Hispanic/Latino origin
Marital status
Marital status at baseline
Age at baseline
Age at baseline assessment
Age at visit
Age at visit (longitudinal)
Age at death
Age at death
Death status
Indicates whether participant died
Depression
Clinical depression
Diagnosis of major depressive disorder made by clinician based on clinical review
Depressive symptoms
Measure of depressive symptoms (Modified CES-D)
Digital Pen Device
Digital pen device data
Number of strokes (Command)
Total number of strokes in command condition
Number of strokes (Copy)
Total number of strokes in copy condition
Completion time (Command)
Total time to completion of command condition
Completion time (Copy)
Total time to completion of copy condition
Percent ink time (Command)
Total time pen is in contact with paper in command condition
Percent ink time (Copy)
Total time pen is in contact with paper in copy condition
Percent think time (Command)
Total time pen is not in contact with paper in command condition
Percent think time (Copy)
Total time pen is not in contact with paper in copy condition
Latency time (Command)
Total latency time in command condition
Latency time (Copy)
Total latency time in copy condition
Disabilities
Basic activities of daily living
Basic activities of daily living - Sum of 6 items
Instrumental activities of daily living
Instrumental activities of daily living - Sum of 8 items
Mobility disability
Mobility disability - Sum of 3 items (Rosow-Breslau scale)
Female Reproductive History
Hormone replacement therapy
HRT
Hormone replacement therapy use
HRT injection
Hormone replacement therapy use: Injection
HRT patch
Hormone replacement therapy use: Patch
HRT pill
Hormone replacement therapy use: Pill
HRT vaginal cream or suppository
Hormone replacement therapy use: Vaginal cream or suppository
Age at start of HRT
Age at first use of hormone replacement therapy
Current HRT use
Current use of hormone replacement therapy
Age at end of HRT
Age at last use of hormone replacement therapy
Menopause/menarche
Menarche age
Age at first occurrence of menstruation
Menopause age
Age at menopause
Cause of menopause
Cause of menopause: Natural or surgical
Surgical cause of menopause
Cause of menopause: Surgical procedure
Surgical cause of menopause - other
Cause of menopause: Other surgical procedure
Frailty
Frailty (categorical)
Categorical frailty measure - 3 levels
Lifestyle
Life space measures
Life space
Distance traveled from home in daily life
Cognitive activity
Cognitive activity - late life
Frequency of participation in cognitively stimulating activity in late life - Average of 7 items
Cognitive activity - middle age
Frequency of participation in cognitively stimulating activity in middle (adult) age - Average of 9 items
Cognitive activity - young adult
Frequency of participation in cognitively stimulating activity as a young adult - Average of 10 items
Cognitive activity - childhood
Frequency of participation in cognitively stimulating activity in childhood - Average of 11 items
Cognitive activity - lifetime (total)
Frequency of participation in cognitively stimulating activity in lifetime - Average of 4 subscales
Driving
Licensed to drive
Currently licensed to drive
Driving status
Driving in past 12 months
Driving frequency
Days driven in a typical week
Physical activity and BMI
BMI
Body mass index
Physical activity (5 items)
Hours of physical activity in late life - Sum of 5 items
Social engagement
Social activity - late life
Frequency of participation in social activity in late life
Social network size
Size of social network based on the number of children, family, and friends seen at least once a month
Loneliness
Perceived social isolation (loneliness)
Perceived social support
Multidemensional Scale of Perceived Social Support - Average of 4 items
Perceived discrimination
Self-reported frequency of discrimination
Alcohol and tobacco use
Alcohol use
Grams of alcohol used per day at baseline
Lifetime daily alcohol intake
Self-reported lifetime daily alcohol intake - baseline
Baseline smoking status (3-level)
Smoking status at baseline (never, former, current smoker)
Medical Conditions
Blood pressure
Systolic blood pressure
Systolic blood pressure - Average of 3 readings
Diastolic blood pressure
Diastolic blood pressure - Average of 3 readings
History of hypertension
Self-reported history of hypertension
Cancer
Cancer at baseline
Self-reported history of cancer at baseline
Diabetes
History of diabetes
Self-reported history of diabetes
Diabetes based on self-report and medication use
Diabetes (self-report + Rx)
Falls
Falls in past year
Falls over the past year, self-reported
Head injury
Head injury loss of consciousness
Self-reported history of head injury with loss of consciousness at baseline
Brain injury severity score
BISQ - Brain injury severity score based on ACRM criteria
Blows to head
BISQ - Total number of blows to head
TBI
BISQ - Presence of traumatic brain injury
TBI with LOC
BISQ - Traumatic brain injury with loss of consciousness
Loss of consciousness
BISQ - Total number of times with loss of consciousness
Longest LOC
BISQ - Longest period of loss of consciousness
Dazed and confused
BISQ - Total number of times dazed and confused
Thyroid
Thyroid disease
Self-reported history of thyroid disease at baseline
Vascular
Vascular disease risk factors
Cumulative vascular disease risk factors - Average of 3 items
Vascular disease burden - 4 items
Cumulative vascular disease burden - Sum of 4 items
Vascular disease burden - 3 items
Cumulative vascular disease burden - Sum of 3 items
History of claudication
Self-reported history of claudication
History of congestive heart failure
Self-reported history of congestive heart failure
History of heart conditions
Self-reported history of heart conditions
History of stroke
History of stroke based on clinician review
Summary measures
Medical conditions (summary)
Self-reported medical condition - baseline
Medicare Claims
Medicare claims data
Medications
Analgesic
Analgesic medication usage in last 2 weeks
Antibiotic
Antibiotic medication usage in last 2 weeks
Anticholinergic
Anticholinergic medication usage in last 2 weeks
Antihypertensive/diuretic
All antihypertensive/diuretic usage in last 2 weeks
Antineoplastic
Antineoplastic medication usage in last 2 weeks
Cardiac
Cardiac medication usage in last 2 weeks
Dermatologic
Dermatologic medication usage in last 2 weeks
Dental
Dental treatment medication usage in last 2 weeks
Endocrine
Endocrine medication usage in last 2 weeks
Gastrointestinal
Gastrointestinal medication usage in last 2 weeks
Hematologic
Hematologic medication usage in last 2 weeks
Lipid-lowering
Lipid-lowering medication usage in last 2 weeks
Mental health
Mental health medication usage in last 2 weeks
Musculoskeletal
Musculoskeletal medication usage in last 2 weeks
Neurologic
Neurologic medication usage in last 2 weeks
Ophthalmic
Ophthalmic medication usage in last 2 weeks
Platelet inhibitor
Platelet inhibitor medication usage in last 2 weeks
Respiratory
Respiratory medication usage in last 2 weeks
Supplements
Supplement usage in last 2 weeks
Urinary
Urinary condition medication usage in last 2 weeks
Antihypertensive medications
Antihypertensive
Antihypertensive medication usage in last 2 weeks
ACE inhibitors
ACE inhibitor usage in last 2 weeks
Angiotensin II receptor blockers
Angiotensin II receptor blocker usage in last 2 weeks
Antiadrenergics
Antiadrenergic usage in last 2 weeks
Beta blocker medications
Beta blocker medication usage in last 2 weeks
Calcium chanel blocker medications
Calcium channel blocker medication usage in last 2 weeks
Direct renin inhibitor medications
Direct renin inhibitor medication usage in last 2 weeks
Other antihypertensive medications
Other antihypertensive medication usage in last 2 weeks
Diuretic medications
Diuretic medication usage in last 2 weeks
Pure diuretic medications
Pure diuretic medication usage in last 2 weeks
Combination diuretic/hypertension medications
Combination diuretic/hypertension medication usage in last 2 weeks
Cardiac medications
Antianginal medications
Antianginal medication usage in last 2 weeks
Antiarrhythmic medications
Antiarrhythmic medication usage in last 2 weeks
Cardiac glycoside medications
Cardiac glycoside medication usage in last 2 weeks
Endocrine medications
Diabetes medications
Diabetes medication usage in last 2 weeks
Estrogen medications
Estrogen medication usage in last 2 weeks
Lipid-lowering medications
Lipid-lowering nonstatins
Lipid-lowering nonstatin usage in last 2 weeks
Statin medications
Statin medication usage in last 2 weeks
Mental health medications
Anti-anxiety medications
Anti-anxiety medication usage in last 2 weeks
Antimanic medications
Antimanic medication usage in last 2 weeks
Antipsychotic medications
Antipsychotic medication usage in last 2 weeks
Depression medications
Depression medication usage in last 2 weeks
Insomnia medications
Insomnia medication usage in last 2 weeks
Tricyclic agents
Tricyclic agent usage in last 2 weeks
Neurologic medications
Alzheimer's disease medications
Alzheimer's disease medication usage in last 2 weeks
Anticonvulsant medications
Anticonvulsant usage in last 2 weeks
Parkinson's disease medications
Parkinson's disease medication usage in last 2 weeks
Metabolism
Brain insulin
Metabolomics
Bile acid
Brain metabolomics
Serum metabolomics
Brain lipidomics
Serum lipidomics
Motor and Gait
Gait device
Motor function measures
Motor function
Motor function composite - Average of 10 tests
Motor dexterity
Motor function partial composite: Dexterity
Motor gait
Motor function partial composite: Gait
Motor hand strength
Motor function partial composite: Hand strength
UPDRS
Parkinsonism
Classification of parkinsonism based on number of parkinsonian signs present - 3 level
Parkinsonian signs
Global parkinsonian summary score
Bradykinesia score
Parkinsonian signs domain: Bradykinesia
Gait score
Parkinsonian signs domain: Gait
Rigidity score
Parkinsonian signs domain: Rigidity
Tremor score
Parkinsonian signs domain: Tremor
Neck, Low Back and Joint Pain
Presence of joint pain
Presence of pain or aching in joints
Joint pain (5 areas)
Joint pain in 5 areas
Joint pain (3 areas)
Joint pain in 3 areas
Lower extremity joint pain
Pain in joints of the lower extermities
Upper extremity joint pain
Pain in joints of the upper extremities
Cervical radiculopathy
Cervical radiculopathy based on self-report
Lumbar radiculopathy
Lumbar radiculopathy based on self-report
Foot pain
Foot pain based on self-report
Hand pain
Hand pain based on self-report
Hip pain
Hip pain based on self-report
Knee pain
Knee pain based on self-report
Neck pain
Neck pain based on self-report
Low back pain
Low back pain based on self-report
Neuroimaging
Ex vivo magnetic resonance imaging (MRI)
In vivo magnetic resonance imaging (MRI)
Gray matter volume
Gray matter volume - percent of intracranial volume
White matter volume
White matter volume - percent of intracranial volume
Cerebrospinal fluid volume
Cerebrospinal fluid volume - percent of intracranial volume
Intracranial volume
Intracranial volume (mm<sup>3</sup>)
White matter hyperintensities volume
Log10 of percent intracranial volume occupied by white matter hyperintensities
ARTS score
Arteriolosclerosis biomarker score
Brain age
Estimated brain age based on structural brain MRI data
Cortical thickness (AD signature)
Cortical thickness for the Alzheimer's disease signature
Nutrition
Diet scores
DASH diet score
Dietary Approach to Stop Hypertension (DASH) diet score
MedDiet score
Mediterranean diet score (MedDiet score)
MIND diet score
Mediterranean-DASH diet intervention for neurodegenerative delay (MIND) diet score
Dietary components
Dietary nutrients
Olfaction
Brief Smell Identification Test measures
Brief Smell Identification Test
Measure of odor identificaiton using the Brief Smell Identification Test
OLFACT device measures
Odor sensitivity
Odor threshold test
Odor identification - phase one
Odor identification - Sum of 10 items (MAP only)
Odor identification - phase two
Odor identification - Sum of 20 items (MAP only)
Odor memory - hits
Odor memory component: Says old, is old (MAP only)
Odor memory - correct rejections
Odor memory component: Says new, is new (MAP only)
Odor memory - incorrect rejections
Odor memory component: Says new, is old (MAP only)
Odor memory - misses
Odor memory component: Says old, is new (MAP only)
Pathology
Alzheimer's disease
A score
Amyloid beta plaque score based on Thal plaque phase (4 levels)
Braak stage
Semiquantitative measure of neurofibrillary tangles
B score
NFT stage (4 levels), derived from Braak Stage
CERAD score
Semiquantitative measure of neuritic plaques
C score
Neuritic plaque score (4 levels), derived from CERAD
Global AD pathology burden
Global burden of AD pathology based on 5 regions
AD neuropathologic change (4 levels)
AD neuropathologic change based on NIA-AA criteria - 4 levels
AD neuropathologic change (2 levels)
AD neuropathologic change based on NIA-AA criteria - 2 levels
NIA-Reagan diagnosis of AD - OLD
NIA-Reagan Diagnosis of Alzheimer's disease - 4 levels (none to high likelihood)
NIA-Reagan diagnosis of AD (dichotomous) - OLD
Presence of AD based on NIA-Reagan diagnosis criteria - dichotomous
Beta-Amyloid
Diffuse plaque burden
Diffuse plaque summary based on 5 regions
Neuritic plaque burden
Neuritic plaque summary based on 5 regions
Amyloid density (8 regions)
Amyloid density after square root transformation
Amyloid - OLD
Overall amyloid level - Mean of 8 brain regions
Neurofibrillary tangles
Neurofibrillary tangles (NFT)
Semi-quantitative summary measure from 5 brain regions
Tangle density (8 regions)
Tangle density after square root transformation
PHF Tau Tangle Density - OLD
Quantitative summary measure from 8 brain regions
Lewy body/PD
Lewy Body disease
Pathologic diagnosis of Lewy body diseases - 4 stages
Lewy bodies (7 regions)
Presence of Lewy bodies in 7 regions (includes amygdala)
Vascular - Infarcts (Presence of)
Presence of one or more gross chronic infarcts
Cerebral Infarctions - Binary - Gross-Chronic-Any Location
Presence of one or more chronic microinfarcts
Cerebral Infarctions - Binary - Micro-Chronic-Any Location
Presence of one or more chronic infarcts
Cerebral Infarctions - Binary - Chronic-Any Size/Location
Vascular - General measures
Cerebral atherosclerosis
Cerebral Atherosclerosis Rating - 4 levels (None - severe)
Cerebral amyloid angiopathy
Cerebral amyloid angiopathy - 4 stages
Arteriolosclerosis
Arteriolosclerosis - 4 stages
Hippocampal sclerosis
Presence of hippocampal sclerosis
Presence of hippocampal sclerosis in mid-hippocampus
TDP-43
TDP-43 stage
TDP-43 pathology - 4 stages (8 regions)
Autopsy - General
Post-mortem interval
Time interval in hours from time of death to autopsy
Pulmonary Function
Pulmonary function composite
Pulmonary Function Composite - Average of 3 components (MAP/CEDHA only)
Maximal inspiratory pressure
Maximal inspiratory pressure (in cm H2O) (MAP only)
Maximal expiratory pressure
Maximal expiratory pressure (in cm H2O) (MAP only)
Possible COPD
Possible COPD - Average of 2 trials
Sleep and Circadian Rhythms
Sensor device measures
Transition probability - Activity to rest
Actical sleep measure - Probability of transitioning from active state to rest state (MAP only)
Transition probability - Rest to activity
Actical sleep measure - Probability of transitioning from rest state to active state (MAP only)
Interdaily stability
Actical measure - Interdaily stability (MAP only)
Intradaily variability
Actical measure - Intradaily variability (MAP only)
Sleep questionnaire
REM sleep behavior disorder: Screen
Presence of possible REM sleep behavior disorder (Mayo Sleep Questionnaire)
REM sleep behavior disorder: Severity
Severity of possible REM sleep behavior disorder (Mayo Sleep Questionnaire)
Restless Legs Syndrome: Screen
Presence of possible Restless Leg Syndrome (Mayo Sleep Questionnaire)
Restless Legs Syndrome: Severity
Severity of possible Restless Legs Syndrome (Mayo Sleep Questionnaire)
SES and Cognitive Resources
SES
Income
Income level at baseline (10-level)
Income - Age 40
Income level at age 40 (10-level)
Parental education level
Years of education completed by parents - Average of 2 items
Maternal education
Years of education completed by mother
Paternal education
Years of education completed by father
Early life SES
Early life socioeconomic status - Average of 3 items
Subjective SES
Subjective socioeconomic status - Average of 2 items
Resources
Total cognitive resources
Access to materials that support cognitive activity - Total (Age 12 and 40)
Cognitive resources - Age 12
Access to materials that support cognitive activity - Age 12
Cognitive resources - Age 40
Access to materials that support cognitive activity - Age 40
Vision
Visual acuity
Near-vision acuity based on Rosenbaum Pocket Vision Screener
Well-being
Purpose in life
Sense of purpose in life
Satisfaction with life
Satisfaction With Life Scale - Average of 5 items
Overall satisfaction
Overall satisfaction with life rating - 1 question
Overall happiness
Overall happiness rating - 1 question
Time horizon
Perceived time horizon - Average of 6 items
Well-being scale
Overall well-being
Overall well-being - Average of 18 items
Hedonic well-being
Well-being subscale: Hedonic - Average of 9 items
Eudaimonic well-being
Well-being subscale: Eudaimonic - Average of 9 items
Well-being: Autonomy
Well-being component: Autonomy - Average of 3 items
Well-being: Environmental mastery
Well-being component: Environmental mastery - Average of 3 items
Well-being: Growth
Well-being component: Growth - Average of 3 items
Well-being: Positive relations with others
Well-being component: Positive relations with others - Average of 3 items
Well-being: Purpose in life
Well-being component: Purpose in life - Average of 3 items
Well-being: Self-acceptance
Well-being component: Self-acceptance - Average of 3 items