RADC Grants

Parent study grants

Study Title PI Grant # Start Date End Date Funding Agency
Rush Alzheimer's Disease Research Center - Religious Orders Study (ROS) Bennett P30AG072975 9/1/21 6/30/26 NIA
Rush Alzheimer's Disease Research Center - African American Clinical Core Barnes P30AG072975 9/1/21 6/30/26 NIA
Rush Alzheimer's Disease Research Center - Latino Core Marquez P30AG072975 9/1/21 6/30/26 NIA
Epidemiologic Study of Neural Reserve and Neurobiology of Aging (MAP) Bennett R01AG017917 9/30/01 3/31/20 NIA
Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease (MARS) Barnes R01AG022018 9/30/04 5/31/26 NIA
Rush Center of Excellence on Disparities in HIV and Aging (CEDHA) Barnes P20MD006886 5/25/12 1/31/19 NIMHD
Pathology, Alzheimer's and Related Diseases Study (PARDoS) Bennett R01AG054058 9/15/16 5/31/23 NIA

Active grants

Study Title PI Grant # Cohort Start Date End Date Funding Agency
1 Dietary factors, Neuroinflammation, Neurovegetative biomarkers and Alzheimer’s Disease in Diverse cohorts Agarwal R01AG085483 09/15/2024 06/30/2029 NIA
2 Dietary factors, Neuroinflammation, Alzheimer's disease biomarkers in Diverse cohorts Agarwal R01AG085483 MAP, MARS, Clinical Core, Latino Core 09/15/2024 06/30/2029 NIA
3 MIND Diet and Dementia Prevention in Ischemic Stroke Patients Aggarwal R01AG062637 09/01/2020 05/31/2026 NIA
4 Examining the brain iron dysregulation in LATE-NC in older adults Agrawal ROS, MAP 07/01/2025 06/30/2026 Rush Faculty Scholors Program
5 In-vivo MRI-based prediction of TDP43 pathology in aging Arfanakis R01AG064233 08/15/2019 04/30/2026 NIA
6 The role of blood and brain 5-hydroxymethylcytosine in linking vascular risk factors to ADRD in older White and Black persons Arvanitakis R01AG074549 08/15/2021 07/31/2026 NIA
7 Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease Barnes R01AG022018 09/30/2004 05/31/2026 NIA
8 Epidemiologic Study of Neural Reserve and Neurobiology of Aging Bennett R01AG017917 09/30/2001 05/31/2026 NIA
9 Rush Alzheimer's Disease Research Center Bennett P30AG072975 09/01/2021 06/30/2026 NIA
10 Whole genome sequencing and admixture analyses of neuropathologic traits in USA and Brazil Bennett R01AG075927 08/15/2023 07/31/2028 NIA
11 Mapping the joint-nerve interactome of the the knee Bennett UC2AR082186 09/23/2022 08/31/2027 NIAMS
12 A Pathway to Precision Medicine for Alzheimer’s Disease and Related Dementias Bennett ROS, MAP 11/08/2024 11/07/2029 Angell Foundation
13 Epidemiologic Study of Decision Making in Preclinical Alzheimer's Disease Boyle R01AG033678 MAP 09/15/2009 12/31/2026 NIA
14 Characterizing the Behavior Profile of Healthy Cognitive Aging Boyle R01AG034374 ROS, MAP 08/15/2009 04/30/2027 NIA
15 Identifying resilience proteins in key motor tissues that drive motor and cognitive decline and offset the negative effects of ADRD pathologies within and outside the brain Buchman R01AG075728 04/01/2022 01/31/2027 NIA
16 Thinking about walking: Can digital phenotyping of mobility improve the prediction of Alzheimer's dementia and inform on the pathologies and proteins contributing to this association Buchman R01AG079133 09/01/2022 05/31/2027 NIA
17 A Novel Epigenetic Clock for Brain Aging Grodstein R01AG069904 08/01/2021 04/30/2026 NIA
18 Mexican Teachers Cohort Study: Genetics and Cognitive Function Grodstein U01AG084547 09/30/2024 08/31/2029 NIA
19 Use of Healthcare Across the Full Continuum of Cognitive Health and Decline in Older Adults Grodstein, Bynum 1R01AG079226-01 ROS, MAP, MARS, Clinical Core, Latino Core 09/30/2022 06/30/2027 NIA
20 Predictors and consequences of the timing and accuracy of clinical dementia diagnosis James, Power R01AG072559 ROS, MAP, MARS, Clinical Core, Latino Core 02/15/2022 01/31/2027 NIA
21 Small vessel disease contributions to neurodegeneration in Alzheimer's disease Kapasi K01AG075177 08/15/2022 07/31/2027 NIA
22 Vascular inflammation in AD Kapasi 900515-0626-02 ROS, MAP, MARS, Clinical Core 07/01/2025 06/30/2026 NIA P30
23 Culturally relevant contributors to cognitive and MRI changes in older Latinos Lamar R01AG062711 01/01/2020 11/30/2026 NIA
24 Mapping the perivascular reticular network in health, aging, and AD Mehta R01AG083765 09/01/2023 08/31/2026 NIH, NIA/NINDS
25 Molecular mechanisms linking cerebrovascular pathologies to AD/ADRD in older adults-Resubmission Oveisgharan R01AG088643 ROS, MAP 07/01/2025 04/30/2030 NIH-NIA
26 Neuropathologic-Epidemiological Study of Metallomics and Alzheimer’s Disease Schneider R01AG054057 09/01/2016 12/31/2026 NIA
27 Rush Alzheimer's Disease Research Center Schneider P30AG072975 ROS, Clinical Core, Latino Core 09/01/2021 06/30/2026 NIA
28 Uncovering intrinsic and extrinsic determinants of selective cellular and regional vulnerability in Alzheimer’s Disease Wang R01AG074082 04/15/2022 03/31/2027 NIA
29 Investigating the Effect of APOE Alleles on Neuro-Immunity of Human Brain Borders in Normal Aging and Alzheimer's Disease Using Sigle-Cell Multi-Omics and In Vitro Organoids Wang R01AG079223 09/01/2022 05/31/2027 NIA
30 Spatial Mapping and Functional Interrogation of Long Noncoding RNAs in Alzheimer’s Disease Wang R01AG074082 ROS, MAP 04/15/2022 03/31/2027 NIA

Completed grants

Study Title PI Grant # Cohort Start Date End Date Funding Agency
1 Diet, Cognition, and Neuroimaging in African American Older Adults Agarwal 07/01/2021 06/30/2022 Rush Internal Grant
2 Maximizing the MIND trial: Analyzing the link between nutrient intake and Parkinson’s Disease characteristics Agarwal 12/23/2020 10/31/2022 Consolidated Anti-Aging Foudnation
3 Diet and Cognition in Older Diverse Men and Women Agarwal AARG-21-852512 01/01/2022 12/31/2023 Alzheimer's Association
4 Dietary Factors, Food security, and Cognition among Older Latinxs Agarwal P30AG072975 01/01/2022 12/31/2022 NIA
5 Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementia Arfanakis UF1NS100599 09/01/2016 07/31/2023 NIA
6 Diffusion anisotropy predicts early AD pathology Arfanakis Contract #23282007 MAP 01/01/2012 12/31/2012 IDPH
7 Post mortem MR imaging of brain tissue in Alzheimer's Disease Arfanakis ROS, MAP, Clinical Core 01/01/2006 12/31/2013 IDPH
8 Oxidative Stress, Aging and Alzheimer's Disease Arvanitakis K23AG023675 ROS 01/15/2005 12/31/2009 NIA
9 Markers of Oxidative Stress and Aging Arvanitakis NIRG-04-1007 ROS 10/01/2004 09/30/2006 Alzheimer's Association
10 Vascular Cognitive and Motor Decline: Impact of aPL Arvanitakis R01AG040039 ROS, MAP 09/30/2011 05/31/2018 NIA
11 Mechanisms linking insulin resistance to brain structure, pathology, and function Arvanitakis, Ahima, Arnold R01NS084965 ROS 07/01/2014 06/30/2021 NINDS
12 Linking peripheral and brain insulin resistance to AD neuropathology and cognition Arvanitakis, Arnold, Ahima RF1AG059621 MAP 08/15/2018 04/30/2023 NIA
13 MIND Diet Intervention to Prevent Alzheimer's Disease Barnes R01AG052583 04/01/2016 03/31/2023 NIA
14 Lipidomics and Brain Health in Older Community Dwelling African Americans Barnes 01/01/2022 12/31/2022 Internal Philanthropic
15 Stress, inflammatory markers, and cognitive decline in older adults Barnes IIRG-07-59818 MAP, MARS 09/01/2007 08/31/2010 Alzheimer's Association
16 CEDHA Administrative Supplement: Sex differences in trauma and resilience Barnes P20MD006886-S1 CEDHA 02/01/2015 01/31/2018 NIMHD
17 Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease — Administrative Supplement Barnes RF1AG022018-11S1 MARS 06/01/2018 03/31/2021 NIA
18 MRI markers of brain aging and risk factors for cognitive decline in older African Americans Barnes R01AG056405 MARS 09/01/2018 05/31/2023 NIA
19 African Ancestry and the Genomic Architecture of AD and Other Common Neurodegenerative Disease Neuropathologies Bennett R01AG054058 09/15/2016 05/31/2024 NIA
20 Rush Alzheimer's Disease Core Center - Religious Orders Study (ROS) Bennett P30AG010161 ROS 09/30/1991 06/30/2021 NIA
21 Rush Alzheimer's Disease Core Center - Clinical Core Bennett P30AG010161 Clinical Core 09/30/1991 06/30/2021 NIA
22 Rush Alzheimer's Disease Core Center - Latino Core Bennett P30AG010161 Latino Core 09/01/2015 06/30/2021 NIA
23 Rush Alzheimer's Disease Core Center (Rush ADCC) Bennett P30AG010161 ROS, Clinical Core, Latino Core 08/15/1997 06/30/2023 NIA
24 Degraded Rationality: Subclinical Neuropathology and Neuroeconomic Behavior in Older Persons Bennett R21AG030765 MAP 09/01/2007 06/30/2010 NIA
25 Cognitive Decline and Dementia: Life Experiences and the Brain Histone Epigenome Bennett RC2AG036547 ROS, MAP 09/30/2009 08/31/2012 NIA
26 Role of TOMM40 '523 and APOE in risk of incident MCI and Alzheimer's disease in longitudinal cohort studies of aging and dementia Bennett ROS, Clinical Core 01/27/2014 01/26/2015 Zinfandel
27 Risk Factors, Pathology, and Clinical Expressions of AD Bennett R01AG015819 ROS, MAP 07/01/1998 04/30/2024 NIA
28 Exploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences Bennett, De Jager RF1AG036042 ROS, MAP 09/15/2009 08/31/2022 NIA
29 Deconstructing and modeling the single cell architecture of the Alzheimer brain Bennett, De Jager RF1AG057473 ROS, MAP 09/15/2017 08/31/2021 NIA
30 Pathway discovery, validation and compound identification for Alzheimer's disease Bennett, De Jager U01AG046152 ROS, MAP 09/20/2013 08/31/2019 NIA
31 Multi-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targets Bennett, De Jager U01AG061356 ROS, MAP 09/30/2018 08/31/2023 NIA
32 Epidemiology of racial differences in decision making among older adults Boyle 09/15/2018 06/30/2023 NIA
33 Effects of Vascular Disease in Mild Cognitive Impairment Boyle K23AG23040 MAP 05/01/2004 04/30/2009 NIA
34 Epidemiology of racial differences in decision making among older adults Boyle R01AG060376 MARS 09/15/2018 06/30/2023 NIA
35 Impaired Gait in Older Adults: Pathologies of Alzheimer's disease and Related Disorders Buchman 08/01/2017 03/31/2023 NIA
36 Risk Factors and the Neurobiologic Substrate of Frailty Buchman R01AG024480 MAP 07/01/2005 06/30/2012 NIA
37 Brain and Spinal Cord Microvascular Pathology in Late-Life Motor Impairment Buchman R01AG043379 MAP 09/30/2012 05/31/2018 NIA
38 Spinal cord and brainstem pathology contributions to late-life gait impairment Buchman R01AG047976 MAP 04/15/2015 01/31/2022 NIA
39 Impaired Gait in Older Adults: Pathologies of Alzheimer's disease and Related Disorders Buchman R01AG056352 MAP 08/01/2017 03/31/2022 NIA
40 The Clinical Profile of Parkinson's Disease (PD) Pathology Buchman R01NS078009 ROS, MAP 09/15/2012 06/30/2018 NINDS
41 Elucidating the Molecular Drivers of Impaired Mobility Within and Outside the CNS in Alzheimer's Disease and Related Disorders Buchman R01AG059732 MAP 05/01/2019 02/29/2024 NIA
42 Quantifying Lower Extremity Joint Motion in Community-Dwelling Older Adults to Elucidate its Contributions to Mobility Limitations, Incident Mobility Disability, and Falls Dawe 09/01/2019 04/30/2024 NIA
43 Quantifying Lower Extremity Joint Motion in Community-Dwelling Older Adults to Elucidate its Contributions to Mobility Limitations, Incident Mobility Disability, and Falls Dawe K25AG061254 MAP 09/01/2019 04/30/2024 NIA
44 Exploring the Role of the Brain Transcriptome in Cognitive Decline De Jager R01AG036836 ROS, MAP 09/15/2011 08/31/2016 NIA
45 Identifying the molecular systems, networks, and key molecules that underlie cognitive resilience Gaiteri R01AG057911 09/15/2017 05/31/2023 NIA
46 Identifying the origins of resilience through human single cell molecular networks, then testing them in diverse, resilient, human IPS lines Gaiteri R01AG061798 09/30/2018 05/31/2024 NIA
47 Identifying the molecular systems, networks, and key molecules that underlie cognitive resilience Gaiteri R01AG057911 ROS, MAP 09/15/2017 05/31/2023 NIA
48 Identifying the origins of resilience through human single cell molecular networks, then testing them in diverse, resilient, human IPS lines Gaiteri R01AG061798 ROS, MAP 09/30/2018 05/31/2025 NIA
49 Rush Alzheimer's Disease Core Center-Diversity Supplement Glover P30AG010161-27S1 MAP, MARS, Clinical Core, Latino Core 04/01/2018 03/31/2020 NIA
50 Brain Imaging of Impaired Financial & Healthcare Decision-Making in Old Age Han Contract #23282006 ROS 01/01/2012 12/31/2012 IDPH
51 Neural Correlates of Impaired Financial & Health Care Decision-Making in Old Age Han K23AG040625 MAP 08/15/2012 04/30/2018 NIA, AFAR
52 Supplement to Neural Correlates of Impaired Financial & Health Care Decision-Making in Old Age Han K23AG040625-S1 Clinical Core 09/15/2014 04/30/2015 NIA
53 Cognitive decline after hospitalization in older adults: predictors and pathogenesis James K01AG050823 MAP 08/15/2015 04/30/2020 NIA
54 Metabolic Networks and Pathways in Alzheimer's Disease Kaddurah-Daouk R01AG046171-S ROS, MAP 05/01/2016 05/31/2019 NIA
55 Rush Alzheimer's Disease Core Center — Administrative Supplement Kapasi P30AG010161-28S1 ROS, Clinical Core, Latino Core 09/30/2018 06/30/2021 NIA
56 Evaluation of a Kidney Transplant Program for Undocumented Immigrants Lange-Maia 02/01/2020 01/31/2023 Gift of Hope
57 Multilevel Contributors to Cognitive and Physical Function Decline in Older African Americans Lange-Maia R03AG071943 06/01/2021 05/31/2023 NIA
58 Sleep, Circadian Rhythms, and Mechanisms of Cognitive Decline in the Human Brain Lim R01AG052488 MAP 03/15/2017 02/28/2025 NIA
59 A Multi-modal Imaging Model to Predict Mobility in Older Adults Poole K01AG064044 09/01/2019 04/30/2023 NIA
60 Diet Patterns and Alzheimer’s Disease and Other Dementias Schneider R01AG054476 08/01/2017 04/30/2024 NIA
61 Characterizing TDP-43 related hippocampal degeneration and memory loss in aging Schneider R01AG067482 06/01/2020 03/31/2025 NIA
62 Epidemiologic study of TDP-43 pathology in aging and dementia Schneider R01AG042210 ROS, MAP 07/01/2012 03/31/2019 NIA
63 Multimodal MRI biomarkers of small vessel disease for older persons with and without dementia Schneider, Arfanakis UH3NS100599 ROS, MAP 09/30/2016 07/31/2021 NINDS
64 Neurobiologic Study of Psychological Distress & Dementia Wilson R01AG024871 ROS 07/01/2006 04/30/2013 NIA
65 Application of Latent and Integrative Approaches to Understand the Spectrum of Cognitive Aging Zammit K01AG054700 03/15/2017 02/28/2023 NIA
66 Physical and mental health pathways to cognitive decline in World Trade Center responders: The roles of pulmonary function and post-traumatic stress disorder Zammit R21AG074708 08/01/2021 10/31/2024 NIA