RADC Grants

Parent study grants

Study Title PI Grant # Start Date End Date Funding Agency
Rush Alzheimer's Disease Research Center - Religious Orders Study (ROS) Bennett P30AG072975 9/1/21 6/30/26 NIA
Rush Alzheimer's Disease Research Center - African American Clinical Core Barnes P30AG072975 9/1/21 6/30/26 NIA
Rush Alzheimer's Disease Research Center - Latino Core Marquez P30AG072975 9/1/21 6/30/26 NIA
Epidemiologic Study of Neural Reserve and Neurobiology of Aging (MAP) Bennett R01AG017917 9/30/01 3/31/20 NIA
Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease (MARS) Barnes R01AG022018 9/30/04 5/31/26 NIA
Rush Center of Excellence on Disparities in HIV and Aging (CEDHA) Barnes P20MD006886 5/25/12 1/31/19 NIMHD
Pathology, Alzheimer's and Related Diseases Study (PARDoS) Bennett R01AG054058 9/15/16 5/31/23 NIA

Active grants

Study Title PI Grant # Cohort Start Date End Date Funding Agency
1 Dietary factors, Neuroinflammation, Alzheimer's disease biomarkers in Diverse cohorts Agarwal R01AG085483 MAP, MARS, Clinical Core, Latino Core 09/15/2024 06/30/2029 NIA
2 Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease Barnes R01AG022018 09/30/2004 05/31/2026 NIA
3 Rush Alzheimer's Disease Research Center Bennett P30AG072975 09/01/2021 06/30/2026 NIA
4 Epidemiologic Study of Decision Making in Preclinical Alzheimer's Disease Boyle R01AG033678 MAP 09/15/2009 12/31/2026 NIA
5 Characterizing the Behavior Profile of Healthy Cognitive Aging Boyle R01AG034374 ROS, MAP 08/15/2009 04/30/2027 NIA
6 Identifying resilience proteins in key motor tissues that drive motor and cognitive decline and offset the negative effects of ADRD pathologies within and outside the brain Buchman R01AG075728 04/01/2022 01/31/2027 NIA
7 A Novel Epigenetic Clock for Brain Aging Grodstein R01AG069904 08/01/2021 04/30/2026 NIA
8 Use of Healthcare Across the Full Continuum of Cognitive Health and Decline in Older Adults Grodstein, Bynum 1R01AG079226-01 ROS, MAP, MARS, Clinical Core, Latino Core 09/30/2022 06/30/2027 NIA
9 Predictors and consequences of the timing and accuracy of clinical dementia diagnosis James, Power R01AG072559 ROS, MAP, MARS, Clinical Core, Latino Core 02/15/2022 01/31/2027 NIA
10 Small vessel disease contributions to neurodegeneration in Alzheimer's disease Kapasi K01AG075177 08/15/2022 07/31/2027 NIA
11 Neuropathologic-Epidemiological Study of Metallomics and Alzheimer’s Disease Schneider R01AG054057 09/01/2016 12/31/2026 NIA
12 Rush Alzheimer's Disease Research Center Schneider P30AG072975 ROS, Clinical Core, Latino Core 09/01/2021 06/30/2026 NIA
13 Uncovering intrinsic and extrinsic determinants of selective cellular and regional vulnerability in Alzheimer’s Disease Wang R01AG074082 04/15/2022 03/31/2027 NIA
14 Investigating the Effect of APOE Alleles on Neuro-Immunity of Human Brain Borders in Normal Aging and Alzheimer's Disease Using Sigle-Cell Multi-Omics and In Vitro Organoids Wang R01AG079223 09/01/2022 05/31/2027 NIA

Completed grants

Study Title PI Grant # Cohort Start Date End Date Funding Agency
1 Diet, Cognition, and Neuroimaging in African American Older Adults Agarwal 07/01/2021 06/30/2022 Rush Internal Grant
2 Maximizing the MIND trial: Analyzing the link between nutrient intake and Parkinson’s Disease characteristics Agarwal 12/23/2020 10/31/2022 Consolidated Anti-Aging Foudnation
3 Diet and Cognition in Older Diverse Men and Women Agarwal AARG-21-852512 01/01/2022 12/31/2023 Alzheimer's Association
4 Dietary Factors, Food security, and Cognition among Older Latinxs Agarwal P30AG072975 01/01/2022 12/31/2022 NIA
5 MIND Diet and Dementia Prevention in Ischemic Stroke Patients Aggarwal R01AG062637 09/01/2020 05/31/2025 NIA
6 Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementia Arfanakis UF1NS100599 09/01/2016 07/31/2023 NIA
7 In-vivo MRI-based prediction of TDP43 pathology in aging Arfanakis R01AG064233 08/15/2019 04/30/2024 NIA
8 Diffusion anisotropy predicts early AD pathology Arfanakis Contract #23282007 MAP 01/01/2012 12/31/2012 IDPH
9 Post mortem MR imaging of brain tissue in Alzheimer's Disease Arfanakis ROS, MAP, Clinical Core 01/01/2006 12/31/2013 IDPH
10 The role of blood and brain 5-hydroxymethylcytosine in linking vascular risk factors to ADRD in older White and Black persons Arvanitakis RF1AG074549 08/15/2021 07/31/2024 NIA
11 Oxidative Stress, Aging and Alzheimer's Disease Arvanitakis K23AG023675 ROS 01/15/2005 12/31/2009 NIA
12 Markers of Oxidative Stress and Aging Arvanitakis NIRG-04-1007 ROS 10/01/2004 09/30/2006 Alzheimer's Association
13 Vascular Cognitive and Motor Decline: Impact of aPL Arvanitakis R01AG040039 ROS, MAP 09/30/2011 05/31/2018 NIA
14 Mechanisms linking insulin resistance to brain structure, pathology, and function Arvanitakis, Ahima, Arnold R01NS084965 ROS 07/01/2014 06/30/2021 NINDS
15 Linking peripheral and brain insulin resistance to AD neuropathology and cognition Arvanitakis, Arnold, Ahima RF1AG059621 MAP 08/15/2018 04/30/2023 NIA
16 MIND Diet Intervention to Prevent Alzheimer's Disease Barnes R01AG052583 04/01/2016 03/31/2023 NIA
17 Lipidomics and Brain Health in Older Community Dwelling African Americans Barnes 01/01/2022 12/31/2022 Internal Philanthropic
18 Stress, inflammatory markers, and cognitive decline in older adults Barnes IIRG-07-59818 MAP, MARS 09/01/2007 08/31/2010 Alzheimer's Association
19 CEDHA Administrative Supplement: Sex differences in trauma and resilience Barnes P20MD006886-S1 CEDHA 02/01/2015 01/31/2018 NIMHD
20 Racial Differences in Late-Life Cognitive decline and risk of Alzheimer's Disease — Administrative Supplement Barnes RF1AG022018-11S1 MARS 06/01/2018 03/31/2021 NIA
21 MRI markers of brain aging and risk factors for cognitive decline in older African Americans Barnes R01AG056405 MARS 09/01/2018 05/31/2023 NIA
22 Epidemiologic Study of Neural Reserve and Neurobiology of Aging Bennett R01AG017917 09/30/2001 05/31/2024 NIA
23 African Ancestry and the Genomic Architecture of AD and Other Common Neurodegenerative Disease Neuropathologies Bennett R01AG054058 09/15/2016 05/31/2024 NIA
24 Rush Alzheimer's Disease Core Center - Religious Orders Study (ROS) Bennett P30AG010161 ROS 09/30/1991 06/30/2021 NIA
25 Rush Alzheimer's Disease Core Center - Clinical Core Bennett P30AG010161 Clinical Core 09/30/1991 06/30/2021 NIA
26 Rush Alzheimer's Disease Core Center - Latino Core Bennett P30AG010161 Latino Core 09/01/2015 06/30/2021 NIA
27 Rush Alzheimer's Disease Core Center (Rush ADCC) Bennett P30AG010161 ROS, Clinical Core, Latino Core 08/15/1997 06/30/2023 NIA
28 Degraded Rationality: Subclinical Neuropathology and Neuroeconomic Behavior in Older Persons Bennett R21AG030765 MAP 09/01/2007 06/30/2010 NIA
29 Cognitive Decline and Dementia: Life Experiences and the Brain Histone Epigenome Bennett RC2AG036547 ROS, MAP 09/30/2009 08/31/2012 NIA
30 Role of TOMM40 '523 and APOE in risk of incident MCI and Alzheimer's disease in longitudinal cohort studies of aging and dementia Bennett ROS, Clinical Core 01/27/2014 01/26/2015 Zinfandel
31 Risk Factors, Pathology, and Clinical Expressions of AD Bennett R01AG015819 ROS, MAP 07/01/1998 04/30/2024 NIA
32 Exploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences Bennett, De Jager RF1AG036042 ROS, MAP 09/15/2009 08/31/2022 NIA
33 Deconstructing and modeling the single cell architecture of the Alzheimer brain Bennett, De Jager RF1AG057473 ROS, MAP 09/15/2017 08/31/2021 NIA
34 Pathway discovery, validation and compound identification for Alzheimer's disease Bennett, De Jager U01AG046152 ROS, MAP 09/20/2013 08/31/2019 NIA
35 Multi-omic network-directed proteoform discovery, dissection and functional validation to prioritize novel AD therapeutic targets Bennett, De Jager U01AG061356 ROS, MAP 09/30/2018 08/31/2023 NIA
36 Epidemiology of racial differences in decision making among older adults Boyle 09/15/2018 06/30/2023 NIA
37 Effects of Vascular Disease in Mild Cognitive Impairment Boyle K23AG23040 MAP 05/01/2004 04/30/2009 NIA
38 Epidemiology of racial differences in decision making among older adults Boyle R01AG060376 MARS 09/15/2018 06/30/2023 NIA
39 Impaired Gait in Older Adults: Pathologies of Alzheimer's disease and Related Disorders Buchman 08/01/2017 03/31/2023 NIA
40 Risk Factors and the Neurobiologic Substrate of Frailty Buchman R01AG024480 MAP 07/01/2005 06/30/2012 NIA
41 Brain and Spinal Cord Microvascular Pathology in Late-Life Motor Impairment Buchman R01AG043379 MAP 09/30/2012 05/31/2018 NIA
42 Spinal cord and brainstem pathology contributions to late-life gait impairment Buchman R01AG047976 MAP 04/15/2015 01/31/2022 NIA
43 Impaired Gait in Older Adults: Pathologies of Alzheimer's disease and Related Disorders Buchman R01AG056352 MAP 08/01/2017 03/31/2022 NIA
44 The Clinical Profile of Parkinson's Disease (PD) Pathology Buchman R01NS078009 ROS, MAP 09/15/2012 06/30/2018 NINDS
45 Elucidating the Molecular Drivers of Impaired Mobility Within and Outside the CNS in Alzheimer's Disease and Related Disorders Buchman R01AG059732 MAP 05/01/2019 02/29/2024 NIA
46 Quantifying Lower Extremity Joint Motion in Community-Dwelling Older Adults to Elucidate its Contributions to Mobility Limitations, Incident Mobility Disability, and Falls Dawe 09/01/2019 04/30/2024 NIA
47 Quantifying Lower Extremity Joint Motion in Community-Dwelling Older Adults to Elucidate its Contributions to Mobility Limitations, Incident Mobility Disability, and Falls Dawe K25AG061254 MAP 09/01/2019 04/30/2024 NIA
48 Exploring the Role of the Brain Transcriptome in Cognitive Decline De Jager R01AG036836 ROS, MAP 09/15/2011 08/31/2016 NIA
49 Identifying the molecular systems, networks, and key molecules that underlie cognitive resilience Gaiteri 09/15/2017 05/31/2023 NIA
50 Identifying the origins of resilience through human single cell molecular networks, then testing them in diverse, resilient, human IPS lines Gaiteri 09/30/2018 05/31/2024 NIA
51 Identifying the molecular systems, networks, and key molecules that underlie cognitive resilience Gaiteri R01AG057911 ROS, MAP 09/15/2017 05/31/2023 NIA
52 Identifying the origins of resilience through human single cell molecular networks, then testing them in diverse, resilient, human IPS lines Gaiteri R01AG061798 ROS, MAP 09/30/2018 05/31/2025 NIA
53 Rush Alzheimer's Disease Core Center-Diversity Supplement Glover P30AG010161-27S1 MAP, MARS, Clinical Core, Latino Core 04/01/2018 03/31/2020 NIA
54 Brain Imaging of Impaired Financial & Healthcare Decision-Making in Old Age Han Contract #23282006 ROS 01/01/2012 12/31/2012 IDPH
55 Neural Correlates of Impaired Financial & Health Care Decision-Making in Old Age Han K23AG040625 MAP 08/15/2012 04/30/2018 NIA, AFAR
56 Supplement to Neural Correlates of Impaired Financial & Health Care Decision-Making in Old Age Han K23AG040625-S1 Clinical Core 09/15/2014 04/30/2015 NIA
57 Cognitive decline after hospitalization in older adults: predictors and pathogenesis James K01AG050823 MAP 08/15/2015 04/30/2020 NIA
58 Metabolic Networks and Pathways in Alzheimer's Disease Kaddurah-Daouk R01AG046171-S ROS, MAP 05/01/2016 05/31/2019 NIA
59 Rush Alzheimer's Disease Core Center — Administrative Supplement Kapasi P30AG010161-28S1 ROS, Clinical Core, Latino Core 09/30/2018 06/30/2021 NIA
60 Culturally relevant contributors to cognitive and MRI changes in older Latinos Lamar R01AG062711 01/01/2020 11/30/2024 NIA
61 Evaluation of a Kidney Transplant Program for Undocumented Immigrants Lange-Maia 02/01/2020 01/31/2023 Gift of Hope
62 Multilevel Contributors to Cognitive and Physical Function Decline in Older African Americans Lange-Maia R03AG071943 06/01/2021 05/31/2023 NIA
63 Sleep, Circadian Rhythms, and Mechanisms of Cognitive Decline in the Human Brain Lim R01AG052488 MAP 03/15/2017 02/28/2025 NIA
64 A Multi-modal Imaging Model to Predict Mobility in Older Adults Poole 09/01/2019 04/30/2023 NIA
65 Diet Patterns and Alzheimer’s Disease and Other Dementias Schneider 08/01/2017 04/30/2023 NIA
66 Characterizing TDP-43 related hippocampal degeneration and memory loss in aging Schneider R01AG067482 06/01/2020 03/31/2025 NIA
67 Epidemiologic study of TDP-43 pathology in aging and dementia Schneider R01AG042210 ROS, MAP 07/01/2012 03/31/2019 NIA
68 Multimodal MRI biomarkers of small vessel disease for older persons with and without dementia Schneider, Arfanakis UH3NS100599 ROS, MAP 09/30/2016 07/31/2021 NINDS
69 Neurobiologic Study of Psychological Distress & Dementia Wilson R01AG024871 ROS 07/01/2006 04/30/2013 NIA
70 Application of Latent and Integrative Approaches to Understand the Spectrum of Cognitive Aging Zammit K01AG054700 03/15/2017 02/28/2023 NIA
71 Physical and mental health pathways to cognitive decline in World Trade Center responders: The roles of pulmonary function and post-traumatic stress disorder Zammit R21AG074708 08/01/2021 04/30/2023 NIA