Study Publications for MAP

Overview of Cohort — Memory and Aging Project (MAP)

Religious Orders Study and Rush Memory and Aging Project
Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA.
J Alzheimers Dis. 64(s1):S161-S189. PubMed PMID: 29865057
Published date: 2018 Jun 12

Overview of Cohort — Memory and Aging Project (MAP)

Overview and findings from the rush Memory and Aging Project.
Bennett DA, Schneider JA, Buchman AS, Barnes LL, Boyle PA, Wilson RS.
Curr Alzheimer Res. 9(6):646-63. PubMed PMID: 22471867
Published date: 2012 Jul


Other Publications

cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM
Cell reports 28 (7):1799-1813.e5. PubMed PMID: 31412248
Published date: 2019 Aug 13
Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease.
Canchi S, Raao B, Masliah D, Rosenthal SB, Sasik R, Fisch KM, De Jager PL, Bennett DA, Rissman RA
Cell reports 28 (4):1103-1116.e4. PubMed PMID: 31340147
Published date: 2019 Jul 23
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
Mahoney ER, Dumitrescu L, Moore AM, Cambronero FE, De Jager PL, Koran MEI, Petyuk VA, Robinson RAS, Goyal S, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ
Molecular psychiatry. PubMed PMID: 31332262
Published date: 2019 Jul 22
Association of Lifespan Cognitive Reserve Indicator With Dementia Risk in the Presence of Brain Pathologies.
Xu H, Yang R, Qi X, Dintica C, Song R, Bennett DA, Xu W
JAMA neurology. PubMed PMID: 31302677
Published date: 2019 Jul 14
Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons.
Kapasi A, Yu L, Stewart CC, Schneider JA, Bennett DA, Boyle PA
Alzheimer disease and associated disorders. PubMed PMID: 31305319
Published date: 2019 Jul 10
Associations of health and financial literacy with mortality in advanced age.
Stewart CC, Yu L, Lamar M, Wilson RS, Bennett DA, Boyle PA
Aging clinical and experimental research. PubMed PMID: 31273677
Published date: 2019 Jul 04
Alzheimer's disease frequency peaks in the tenth decade and is lower afterwards.
Farfel JM, Yu L, Boyle PA, Leurgans S, Shah RC, Schneider JA, Bennett DA
Acta neuropathologica communications 7 (1):104. PubMed PMID: 31269985
Published date: 2019 Jul 03
Different combinations of mobility metrics derived from a wearable sensor are associated with distinct health outcomes in older adults.
Buchman AS, Dawe RJ, Leurgans SE, Curran TA, Truty T, Yu L, Barnes LL, Hausdorff JM, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences. PubMed PMID: 31246244
Published date: 2019 Jun 27
Associations Between Depression, Traumatic Brain Injury, and Cognitively-Defined Late-Onset Alzheimer's Disease Subgroups.
Bauman J, Gibbons LE, Moore M, Mukherjee S, McCurry SM, McCormick W, Bowen JD, Trittschuh E, Glymour M, Mez J, Saykin AJ, Dams-O'Conner K, Bennett DA, Larson EB, Crane PK
Journal of Alzheimer's disease : JAD 70 (2):609-617. PubMed PMID: 31256124
Published date: 2019 Jun 24
Quantitative mobility metrics from a wearable sensor predict incident parkinsonism in older adults.
von Coelln R, Dawe RJ, Leurgans SE, Curran TA, Truty T, Yu L, Barnes LL, Shulman JM, Shulman LM, Bennett DA, Hausdorff JM, Buchman AS
Parkinsonism & related disorders. PubMed PMID: 31272924
Published date: 2019 Jun 22
Financial and health literacy discrepancies with cognition in older adults.
Weissberger GH, Han SD, Yu L, Barnes LL, Bennett DA, Boyle PA
Neuropsychology. PubMed PMID: 31204814
Published date: 2019 Jun 17
A coordinated multi-study analysis of the longitudinal association between handgrip strength and cognitive function in older adults.
Zammit AR, Piccinin AM, Duggan EC, Koval A, Clouston S, Robitaille A, Brown CL, Handschuh P, Wu C, Jarry V, Finkel D, Graham RB, Muniz-Terrera G, Bjrk MP, Bennett D, Deeg DJ, Johansson B, Katz MJ, Kaye J, Lipton RB, Martin M, Pederson NL, Spiro A, Zimpric
The journals of gerontology. Series B, Psychological sciences and social sciences. PubMed PMID: 31187137
Published date: 2019 Jun 11
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
Nagpal S, Meng X, Epstein MP, Tsoi LC, Patrick M, Gibson G, De Jager PL, Bennett DA, Wingo AP, Wingo TS, Yang J
American journal of human genetics 105 (2):258-266. PubMed PMID: 31230719
Published date: 2019 Jun 10
Motoric cognitive risk syndrome and predictors of transition to dementia: A multicenter study.
Verghese J, Wang C, Bennett DA, Lipton RB, Katz MJ, Ayers E
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (7):870-877. PubMed PMID: 31164315
Published date: 2019 Jun 01
Strawberry Consumption Associated with Reduced Alzheimer's Dementia Risk (FS05-06-19).
Agarwal P, Wang Y, Holland T, Bennett D, Morris M
Current developments in nutrition. PubMed PMID: 31223711
Published date: 2019 Jun
Rate of brain aging and APOE 4 are synergistic risk factors for Alzheimer's disease.
Glorioso CA, Pfenning AR, Lee SS, Bennett DA, Sibille EL, Kellis M, Guarente LP
Life science alliance. PubMed PMID: 31133613
Published date: 2019 Jun
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, Lunetta KL
Aging cell 18 (4):e12964. PubMed PMID: 31144443
Published date: 2019 May 29
Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer's Disease Patients.
Tobin MK, Musaraca K, Disouky A, Shetti A, Bheri A, Honer WG, Kim N, Dawe RJ, Bennett DA, Arfanakis K, Lazarov O
Cell stem cell 24 (6):974-982.e3. PubMed PMID: 31130513
Published date: 2019 May 16
Genome-wide association studies of alcohol dependence, DSM-IV criterion count, and individual criteria.
Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hari
Genes, brain, and behavior 18 (6):e12579. PubMed PMID: 31090166
Published date: 2019 May 14
Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology.
Arvanitakis Z, Capuano AW, Brey R, Fleischman DA, Arfanakis K, Buchman AS, Schneider JA, Levine SR, Bennett DA
Neuroepidemiology 53 (1-2):1-8. PubMed PMID: 31067547
Published date: 2019 May 08
Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease.
Tosto G, Vardarajan B, Sariya S, Brickman AM, Andrews H, Manly JJ, Schupf N, Reyes-Dumeyer D, Lantigua R, Bennett DA, De Jager PL, Mayeux R
JAMA neurology. PubMed PMID: 31058951
Published date: 2019 May 06
Total daily physical activity and the risk of parkinsonism in community-dwelling older adults.
Oveisgharan S, Yu L, Dawe RJ, Bennett DA, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences. PubMed PMID: 31046115
Published date: 2019 May 02
Single-cell transcriptomic analysis of Alzheimer's disease.
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH
Nature 570 (7761):332-337. PubMed PMID: 31042697
Published date: 2019 May 01
Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.
Yu L, Petyuk VA, Tasaki S, Boyle PA, Gaiteri C, Schneider JA, De Jager PL, Bennett DA
JAMA neurology 34 (4):493-511. PubMed PMID: 31009033
Published date: 2019 Apr 22
White matter correlates of scam susceptibility in community-dwelling older adults.
Lamar M, Arfanakis K, Yu L, Zhang S, Han SD, Fleischman DA, Bennett DA, Boyle PA
Brain imaging and behavior. PubMed PMID: 30895444
Published date: 2019 Mar 20
Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.
Buchman AS, Yu L, Wilson RS, Leurgans SE, Nag S, Shulman JL, Barnes LL, Schneider JA, Bennett DA
Neurology 92 (16):e1821-e1830. PubMed PMID: 30894446
Published date: 2019 Mar 20
Healthcare and Financial Decision Making and Incident Adverse Cognitive Outcomes among Older Adults.
Stewart CC, Yu L, Wilson RS, Bennett DA, Boyle PA
Journal of the American Geriatrics Society 67 (8):1590-1595. PubMed PMID: 30882910
Published date: 2019 Mar 18
Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons.
Capuano AW, Wilson RS, Honer WG, Petyuk VA, Leurgans SE, Yu L, Gatchel JR, Arnold S, Bennett DA, Arvanitakis Z
Journal of affective disorders. PubMed PMID: 30875674
Published date: 2019 Mar 08
A Multi-Study Coordinated Meta-Analysis of Pulmonary Function and Cognition in Aging.
Duggan EC, Piccinin AM, Clouston S, Koval AV, Robitaille A, Zammit AR, Wu C, Brown CL, Lee LO, Finkel D, Beasley WH, Kaye J, Muniz-Terrera G, Katz M, Lipton RB, Deeg D, Bennett DA, Björk MP, Johansson B, Spiro A, Weuve J, Hofer SM
The journals of gerontology. Series A, Biological sciences and medical sciences. PubMed PMID: 30825374
Published date: 2019 Mar 02
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.
Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (3):441-452. PubMed PMID: 30503768
Published date: 2019 Mar
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A, tau, immunity and lipid processing.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, R
Nature genetics 51 (3):414-430. PubMed PMID: 30820047
Published date: 2019 03
Associations of literacy with diabetes indicators in older adults.
Lamar M, Wilson RS, Yu L, James BD, Stewart CC, Bennett DA, Boyle PA
Journal of epidemiology and community health 73 (3):250-255. PubMed PMID: 30530520
Published date: 2019 Mar
Hippocampal gene expression patterns linked to late-life physical activity oppose age and AD-related transcriptional decline.
Berchtold NC, Prieto GA, Phelan M, Gillen DL, Baldi P, Bennett DA, Buchman AS, Cotman CW
Neurobiology of aging. PubMed PMID: 30927700
Published date: 2019 Feb 20
Education and cognitive reserve in old age.
Wilson RS, Yu L, Lamar M, Schneider JA, Boyle PA, Bennett DA
Neurology 92 (10):e1041-e1050. PubMed PMID: 30728309
Published date: 2019 Feb 06
Disentangling the genetics of lean mass.
Karasik D, Zillikens MC, Hsu YH, Aghdassi A, Akesson K, Amin N, Barroso I, Bennett DA, Bertram L, Bochud M, Borecki IB, Broer L, Buchman AS, Byberg L, Campbell H, Campos-Obando N, Cauley JA, Cawthon PM, Chambers JC, Chen Z, Cho NH, Choi HJ, Chou WC, Cummi
The American journal of clinical nutrition 109 (2):276-287. PubMed PMID: 30721968
Published date: 2019 Feb 05
Investigation of frailty as a moderator of the relationship between neuropathology and dementia in Alzheimer's disease: a cross-sectional analysis of data from the Rush Memory and Aging Project.
Wallace LMK, Theou O, Godin J, Andrew MK, Bennett DA, Rockwood K
The Lancet. Neurology 18 (2):177-184. PubMed PMID: 30663607
Published date: 2019 Feb
Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.
Makkinejad N, Schneider JA, Yu J, Leurgans SE, Kotrotsou A, Evia AM, Bennett DA, Arfanakis K
Neurobiology of aging 77 (11):104-111. PubMed PMID: 30784812
Published date: 2019 Jan 31
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
Felsky D, Roostaei T, Nho K, Risacher SL, Bradshaw EM, Petyuk V, Schneider JA, Saykin A, Bennett DA, De Jager PL
Nature communications 10 (1):409. PubMed PMID: 30679421
Published date: 2019 Jan 24
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, Kukull WA, Tosun D, Weiner MW, Sperling RA, Bennett DA, Hyman BT, Andreassen OA, Dale AM,
Brain : a journal of neurology 142 (2):460-470. PubMed PMID: 30689776
Published date: 2019 Jan 24
Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
Wilson RS, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Bennett DA, Boyle PA
Neurology 92 (8):e831-e840. PubMed PMID: 30674595
Published date: 2019 Jan 23
Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain.
Dintica CS, Marseglia A, Rizzuto D, Wang R, Seubert J, Arfanakis K, Bennett DA, Xu W
Neurology 92 (7):e700-e709. PubMed PMID: 30651382
Published date: 2019 Jan 16
Physical activity, common brain pathologies, and cognition in community-dwelling older adults.
Buchman AS, Yu L, Wilson RS, Lim A, Dawe RJ, Gaiteri C, Leurgans SE, Schneider JA, Bennett DA
Neurology 92 (8):e811-e822. PubMed PMID: 30651386
Published date: 2019 Jan 16
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartans
Neurology. PubMed PMID: 30651383
Published date: 2019 Jan 16
Causes and Patterns of Dementia: An Update in the Era of Redefining Alzheimer's Disease.
James BD, Bennett DA
Annual review of public health. PubMed PMID: 30642228
Published date: 2019 Jan 14
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
Karlsson Linnér R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Zünd CL, Bao Y, Buzdugan L, Caplin AH, Chen CY, Eibich P, F
Nature genetics 51 (2):245-257. PubMed PMID: 30643258
Published date: 2019 Jan 14
Cognitive decline after elective and nonelective hospitalizations in older adults.
James BD, Wilson RS, Capuano AW, Boyle PA, Shah RC, Lamar M, Ely EW, Bennett DA, Schneider JA
Neurology 92 (7):e690-e699. PubMed PMID: 30635482
Published date: 2019 Jan 11
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupki
Communications biology. PubMed PMID: 31396565
Published date: 2019
Cognition may link cortical IGFBP5 levels with motor function in older adults.
Buchman AS, Yu L, Petyuk VA, Gaiteri C, Tasaki S, Blizinsky KD, Schneider JA, De Jager PL, Bennett DA
PloS one 14 (8):e0220968. PubMed PMID: 31404102
Published date: 2019
Expanding instrumented gait testing in the community setting: A portable, depth-sensing camera captures joint motion in older adults.
Dawe RJ, Yu L, Leurgans SE, Truty T, Curran T, Hausdorff JM, Wimmer MA, Block JA, Bennett DA, Buchman AS
PloS one 14 (5):e0215995. PubMed PMID: 31091267
Published date: 2019
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL
Nature neuroscience 22 (1):37-46. PubMed PMID: 30559478
Published date: 2019 Jan
DNA methylation variability in Alzheimer's disease.
Huo Z, Zhu Y, Yu L, Yang J, De Jager P, Bennett DA, Zhao J
Neurobiology of aging. PubMed PMID: 30660039
Published date: 2018 Dec 21
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
Mukherjee S, Mez J, Trittschuh EH, Saykin AJ, Gibbons LE, Fardo DW, Wessels M, Bauman J, Moore M, Choi SE, Gross AL, Rich J, Louden DKN, Sanders RE, Grabowski TJ, Bird TD, McCurry SM, Snitz BE, Kamboh MI, Lopez OL, De Jager PL, Bennett DA, Keene CD, Larso
Molecular psychiatry. PubMed PMID: 30514930
Published date: 2018 Dec 04
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
Beecham GW, Vardarajan B, Blue E, Bush W, Jaworski J, Barral S, DeStefano A, Hamilton-Nelson K, Kunkle B, Martin ER, Naj A, Rajabli F, Reitz C, Thornton T, van Duijn C, Goate A, Seshadri S, Farrer LA, Boerwinkle E, Schellenberg G, Haines JL, Wijsman E, Ma
Neurology. Genetics 4 (6):e286. PubMed PMID: 30569016
Published date: 2018 Dec
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V, Starks T, Byfield GE, Sierra Lopez CB, McCauley JL, Acosta H, Chinea A, Kunkle BW, Reitz C, Farrer LA, Schellenberg GD, Vardar
PLoS genetics 14 (12):e1007791. PubMed PMID: 30517106
Published date: 2018 12
Subtypes Based on Neuropsychological Performance Predict Incident Dementia: Findings from the Rush Memory and Aging Project.
Zammit AR, Muniz-Terrera G, Katz MJ, Hall CB, Ezzati A, Bennett DA, Lipton RB
Journal of Alzheimer's disease : JAD 67 (1):125-135. PubMed PMID: 30507576
Published date: 2018 Nov 29
Quantitative Assessment of Pathological Tau Burden in Essential Tremor: A Postmortem Study.
Farrell K, Cosentino S, Iida MA, Chapman S, Bennett DA, Faust PL, Louis ED, Crary JF
Journal of neuropathology and experimental neurology 78 (1):31-37. PubMed PMID: 30476290
Published date: 2018 Nov 23
Spinal motor neurons and motor function in older adults.
Buchman AS, Leurgans SE, VanderHorst VGJM, Nag S, Schneider JA, Bennett DA
Journal of neurology 266 (1):174-182. PubMed PMID: 30446967
Published date: 2018 Nov 16
Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies.
Boyle PA, Yu L, Leurgans SE, Wilson RS, Brookmeyer R, Schneider JA, Bennett DA
Annals of neurology 85 (1):114-124. PubMed PMID: 30421454
Published date: 2018 Nov 12
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vanc
Acta neuropathologica 137 (2):209-226. PubMed PMID: 30413934
Published date: 2018 Nov 09
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
Sullivan SE, Liao M, Smith RV, White C, Lagomarsino VN, Xu J, Taga M, Bennett DA, De Jager PL, Young-Pearse TL
Human molecular genetics 28 (5):718-735. PubMed PMID: 30371777
Published date: 2018 Oct 26
In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.
Hanko V, Apple AC, Alpert KI, Warren KN, Schneider JA, Arfanakis K, Bennett DA, Wang L
Neurobiology of aging. PubMed PMID: 30453234
Published date: 2018 Oct 25
The transition between turning and sitting in patients with Parkinson's disease: A wearable device detects an unexpected sequence of events.
Weiss A, Herman T, Mirelman A, Shiratzky SS, Giladi N, Barnes LL, Bennett DA, Buchman AS, Hausdorff JM
Gait & posture. PubMed PMID: 30380506
Published date: 2018 Oct 21
Sex differences in Alzheimer's disease and common neuropathologies of aging.
Oveisgharan S, Arvanitakis Z, Yu L, Farfel J, Schneider JA, Bennett DA
Acta neuropathologica 136 (6):887-900. PubMed PMID: 30334074
Published date: 2018 Oct 17
APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults.
Lamar M, Yu L, Rubin LH, James BD, Barnes LL, Farfel JM, Gaiteri C, Buchman AS, Bennett DA, Schneider JA
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (2):258-266. PubMed PMID: 30321502
Published date: 2018 Oct 12
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, Louie G, Kueider-Paisley A, Moseley MA, Thompson JW, St John Williams L, Tenenbaum JD, Blach C, Baillie R, Han X, Bhattacharyya S, Toledo JB, Schafferer S, Klein S, Koal T, Risacher SL, Kling M
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (1):76-92. PubMed PMID: 30337151
Published date: 2018 Oct 08
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, Bennett DA, De Jager PL
Nature genetics 50 (11):1584-1592. PubMed PMID: 30297968
Published date: 2018 Oct 08
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral AB amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reduc
Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME
Molecular psychiatry 24 (3):431-446. PubMed PMID: 30283032
Published date: 2018 Oct 03
Deconstructing and targeting the genomic architecture of human neurodegeneration.
De Jager PL, Yang HS, Bennett DA
Nature neuroscience 21 (10):1310-1317. PubMed PMID: 30258235
Published date: 2018 Oct
Dietary Patterns and Self-reported Incident Disability in Elderly.
Agarwal P, Wang Y, Buchman AS, Bennett DA, Morris MC
The journals of gerontology. Series A, Biological sciences and medical sciences. PubMed PMID: 30247552
Published date: 2018 Sep 21
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
Lim ASP, Gaiteri C, Yu L, Sohail S, Swardfager W, Tasaki S, Schneider JA, Paquet C, Stuss DT, Masellis M, Black SE, Hugon J, Buchman AS, Barnes LL, Bennett DA, De Jager PL
PLoS medicine 15 (9):e1002647. PubMed PMID: 30180184
Published date: 2018 Sep
Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study.
Yang HS, Yu L, White CC, Chibnik LB, Chhatwal JP, Sperling RA, Bennett DA, Schneider JA, De Jager PL
The Lancet. Neurology 17 (9):773-781. PubMed PMID: 30093249
Published date: 2018 Sep
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, De Jager P, Schneider JA, Morris CM, McKeith IG, Perry RH, Lovestone S, Woltjer RL
Brain : a journal of neurology 141 (9):2721-2739. PubMed PMID: 30137212
Published date: 2018 Aug 20
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples
Molecular psychiatry. PubMed PMID: 30108311
Published date: 2018 Aug 14
Differences in the Associations between Memory Complaints and Depressive Symptoms among Black and White Older Adults.
Hill NL, Mogle J, Bhargava S, Whitaker E, Bhang IY, Capuano AW, Arvanitakis Z, Bennett DA, Barnes LL
The journals of gerontology. Series B, Psychological sciences and social sciences. PubMed PMID: 30102393
Published date: 2018 Aug 09
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.
Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, Ikram MA, Mayeux R, Farrer LA, Haines JL, Pericak-Vance MA, Schellenbe
Neurobiology of aging. PubMed PMID: 30201328
Published date: 2018 Aug 09
A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA
Scientific data. PubMed PMID: 30084846
Published date: 2018 Aug 07
Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
Bove RM, Patrick E, Aubin CM, Srivastava G, Schneider JA, Bennett DA, De Jager PL, Chibnik LB
PloS one 13 (7):e0199073. PubMed PMID: 30052629
Published date: 2018
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
Felsky D, Patrick E, Schneider JA, Mostafavi S, Gaiteri C, Patsopoulos N, Bennett DA, De Jager PL
Molecular neurodegeneration 13 (1):38. PubMed PMID: 30041668
Published date: 2018 Jul 24
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linne?r R, Fontana MA, Kundu T, Lee C, Li H, Li R, Royer R, Timshel PN, Walters RK, Willoughby EA, Yengo L, Alver M, Bao Y, Clark DW, Day FR, Furlotte
Nature genetics 50 (8):1112-1121. PubMed PMID: 30038396
Published date: 2018 Jul 23
Late-life blood pressure association with cerebrovascular and Alzheimer disease pathology.
Arvanitakis Z, Capuano AW, Lamar M, Shah RC, Barnes LL, Bennett DA, Schneider JA
Neurology 91 (6):e517-e525. PubMed PMID: 29997190
Published date: 2018 Jul 11
White matter correlates of temporal discounting in older adults.
Han SD, Arfanakis K, Fleischman DA, Yu L, Bennett DA, Boyle PA
Brain structure & function 223 (8):3653-3663. PubMed PMID: 29992469
Published date: 2018 Jul 10
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, John
Acta neuropathologica 136 (6):857-872. PubMed PMID: 29967939
Published date: 2018 Jul 02
Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation.
Cheng H, Xuan H, Green CD, Han Y, Sun N, Shen H, McDermott J, Bennett DA, Lan F, Han JJ
Proceedings of the National Academy of Sciences of the United States of America 115 (29):7611-7616. PubMed PMID: 29967166
Published date: 2018 Jul 02
Association of Financial Literacy With Hospitalization in Community-dwelling Older Adults.
James BD, Wilson RS, Shah RC, Yu L, Arvanitakis Z, Bennett DA, Boyle PA
Medical care 56 (7):596-602. PubMed PMID: 29901572
Published date: 2018 Jul
Combined neuropathological pathways account for age-related risk of dementia.
Power MC, Mormino E, Soldan A, James BD, Yu L, Armstrong NM, Bangen KJ, Delano-Wood L, Lamar M, Lim YY, Nudelman K, Zahodne L, Gross AL, Mungas D, Widaman KF, Schneider J
Annals of neurology 84 (1):10-22. PubMed PMID: 29944741
Published date: 2018 Jul
Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics.
Gaiteri C, Dawe R, Mostafavi S, Blizinsky KD, Tasaki S, Komashko V, Yu L, Wang Y, Schneider JA, Arfanakis K, De Jager PL, Bennett DA
Brain imaging and behavior 13 (4):963-972. PubMed PMID: 29934819
Published date: 2018 Jun 22
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT
Neuron 99 (1):64-82.e7. PubMed PMID: 29937276
Published date: 2018 Jun 21
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Yu L, Petyuk VA, Gaiteri C, Mostafavi S, Young-Pearse T, Shah RC, Buchman AS, Schneider JA, Piehowski PD, Sontag RL, Fillmore TL, Shi T, Smith RD, De Jager PL, Bennett DA
Annals of neurology 84 (1):78-88. PubMed PMID: 29908079
Published date: 2018 Jun 16
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D, Akbarian S, Roussos P, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK
American journal of human genetics 102 (6):1169-1184. PubMed PMID: 29805045
Published date: 2018 Jun 07
Tau Activates Transposable Elements in Alzheimer's Disease.
Guo C, Jeong HH, Hsieh YC, Klein HU, Bennett DA, De Jager PL, Liu Z, Shulman JM
Cell reports 23 (10):2874-2880. PubMed PMID: 29874575
Published date: 2018 Jun 05
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL
Nature neuroscience 21 (6):811-819. PubMed PMID: 29802388
Published date: 2018 Jun
Watershed microinfarct pathology and cognition in older persons.
Kapasi A, Leurgans SE, James BD, Boyle PA, Arvanitakis Z, Nag S, Bennett DA, Buchman AS, Schneider JA
Neurobiology of aging. PubMed PMID: 29935416
Published date: 2018 May 30
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoum
Nature communications 9 (1):2098. PubMed PMID: 29844566
Published date: 2018 May 29
Religious Orders Study and Rush Memory and Aging Project.
Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA
Journal of Alzheimer's disease : JAD 64 (s1):S161-S189. PubMed PMID: 29865057
Published date: 2018 May 26
Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults.
Dawe RJ, Yu L, Schneider JA, Arfanakis K, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29908416
Published date: 2018 May 23
Variability and Coupling of Olfactory Identification and Episodic Memory in Older Adults.
Knight JE, Bennett DA, Piccinin AM
The journals of gerontology. Series B, Psychological sciences and social sciences. PubMed PMID: 29762752
Published date: 2018 May 14
APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.
Oveisgharan S, Buchman AS, Yu L, Farfel J, Hachinski V, Gaiteri C, De Jager PL, Schneider JA, Bennett DA
Neurology 90 (24):e2127-e2134. PubMed PMID: 29752306
Published date: 2018 May 11
Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnso
JAMA neurology 75 (8):989-998. PubMed PMID: 29801024
Published date: 2018 May 07
Fractal regulation and incident Alzheimer's disease in elderly individuals.
Li P, Yu L, Lim ASP, Buchman AS, Scheer FAJL, Shea SA, Schneider JA, Bennett DA, Hu K
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (9):1114-1125. PubMed PMID: 29733807
Published date: 2018 May 04
TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.
Nag S, Yu L, Boyle PA, Leurgans SE, Bennett DA, Schneider JA
Acta neuropathologica communications 6 (1):33. PubMed PMID: 29716643
Published date: 2018 May 01
Positional effects revealed in Illumina methylation array and the impact on analysis.
Jiao C, Zhang C, Dai R, Xia Y, Wang K, Giase G, Chen C, Liu C
Epigenomics 10 (5):643-659. PubMed PMID: 29469594
Published date: 2018 May
Effect of Antidepressant Medication Use and Social Engagement on the Level of Depressive Symptoms in Community-Dwelling, Older African Americans and Whites With Dementia.
Rodrigues J, Capuano AW, Barnes LL, Bennett DA, Shah RC
Journal of aging and health 31 (7):898264318772983. PubMed PMID: 29742953
Published date: 2018 May 01
Brain pathology is related to total daily physical activity in older adults.
Buchman AS, Dawe RJ, Yu L, Lim A, Wilson RS, Schneider JA, Bennett DA
Neurology 90 (21):e1911-e1919. PubMed PMID: 29695600
Published date: 2018 Apr 25
An epigenetic biomarker of aging for lifespan and healthspan.
Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S
Aging 10 (4):573-591. PubMed PMID: 29676998
Published date: 2018 04 18
Association Between Quantitative Gait and Balance Measures and Total Daily Physical Activity in Community-Dwelling Older Adults.
Dawe RJ, Leurgans SE, Yang J, Bennett JM, Hausdorff JM, Lim AS, Gaiteri C, Bennett DA, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (5):636-642. PubMed PMID: 28957994
Published date: 2018 Apr 17
Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.
Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM
Genome medicine 10 (1):26. PubMed PMID: 29598827
Published date: 2018 Mar 29
Correlates of healthcare and financial decision making among older adults without dementia.
Stewart CC, Yu L, Wilson RS, Bennett DA, Boyle PA
Health psychology : official journal of the Division of Health Psychology, American Psychological Association 37 (7):618-626. PubMed PMID: 29565601
Published date: 2018 Mar 22
Neurodegenerative disease and cognitive retest learning.
Wilson RS, Capuano AW, Yu L, Yang J, Kim N, Leurgans SE, Lamar M, Schneider JA, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29558667
Published date: 2018 Mar 17
Time-to-event data with time-varying biomarkers measured only at study entry, with applications to Alzheimer's disease.
Lee C, Betensky RA
Statistics in medicine 37 (6):914-932. PubMed PMID: 29266591
Published date: 2018 Mar 15
Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, Lunnon K
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (12):1580-1588. PubMed PMID: 29550519
Published date: 2018 Mar 14
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Wang X, Philip VM, Ananda G, White CC, Malhotra A, Michalski PJ, Karuturi KRM, Chintalapudi SR, Acklin C, Sasner M, Bennett DA, De Jager PL, Howell GR, Carter GW
Genetics 209 (1):51-64. PubMed PMID: 29507048
Published date: 2018 Mar 05
Frontotemporal dysregulation of the SNARE protein interactome is associated with faster cognitive decline in old age.
Ramos-Miguel A, Jones AA, Sawada K, Barr AM, Bayer TA, Falkai P, Leurgans SE, Schneider JA, Bennett DA, Honer WG
Neurobiology of disease. PubMed PMID: 29496544
Published date: 2018 Feb 26
A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans.
McAninch EA, Rajan KB, Evans DA, Jo S, Chaker L, Peeters RP, Bennett DA, Mash DC, Bianco AC
The Journal of clinical endocrinology and metabolism 103 (5):1818-1826. PubMed PMID: 29481662
Published date: 2018 Feb 22
Memory complaints, dementia, and neuropathology in older blacks and whites.
Arvanitakis Z, Leurgans SE, Fleischman DA, Schneider JA, Rajan KB, Pruzin JJ, Shah RC, Evans DA, Barnes LL, Bennett DA
Annals of neurology 83 (4):718-729. PubMed PMID: 29466839
Published date: 2018 Feb 21
Longitudinal Modeling of Functional Decline Associated with Pathologic Alzheimer's Disease in Older Persons without Cognitive Impairment.
Wang D, Schultz T, Novak GP, Baker S, Bennett DA, Narayan VA
Journal of Alzheimer's disease : JAD 62 (2):855-865. PubMed PMID: 29480187
Published date: 2018
Accelerometer Physical Activity is Associated with Greater Gray Matter Volumes in Older Adults without Dementia or Mild Cognitive Impairment.
Halloway S, Arfanakis K, Wilbur J, Schoeny ME, Pressler SJ
The journals of gerontology. Series B, Psychological sciences and social sciences. PubMed PMID: 29432610
Published date: 2018 Feb 08
A transcriptomic atlas of aged human microglia.
Olah M, Patrick E, Villani AC, Xu J, White CC, Ryan KJ, Piehowski P, Kapasi A, Nejad P, Cimpean M, Connor S, Yung CJ, Frangieh M, McHenry A, Elyaman W, Petyuk V, Schneider JA, Bennett DA, De Jager PL, Bradshaw EM
Nature communications 9 (1):539. PubMed PMID: 29416036
Published date: 2018 Feb 07
CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P
Neurology. Genetics 4 (1):e216. PubMed PMID: 29473050
Published date: 2018 Feb
Transitions across cognitive states and death among older adults in relation to education: A multistate survival model using data from six longitudinal studies.
Robitaille A, van den Hout A, Machado RJM, Bennett DA, C?ukic? I, Deary IJ, Hofer SM, Hoogendijk EO, Huisman M, Johansson B, Koval AV, van der Noordt M, Piccinin AM, Rijnhart JJM, Singh-Manoux A, Skoog J, Skoog I, Starr J, Vermunt L, Clouston S, Muniz Ter
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (4):462-472. PubMed PMID: 29396108
Published date: 2018 Jan 25
Loneliness 5 years ante-mortem is associated with disease-related differential gene expression in postmortem dorsolateral prefrontal cortex.
Canli T, Yu L, Yu X, Zhao H, Fleischman D, Wilson RS, De Jager PL, Bennett DA
Translational psychiatry 8 (1):2. PubMed PMID: 29317593
Published date: 2018 Jan 10
Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline.
Tasaki S, Gaiteri C, Mostafavi S, Yu L, Wang Y, De Jager PL, Bennett DA
Frontiers in genetics. PubMed PMID: 30140277
Published date: 2018
Bivariate Causal Discovery and Its Applications to Gene Expression and Imaging Data Analysis.
Jiao R, Lin N, Hu Z, Bennett DA, Jin L, Xiong M
Frontiers in genetics. PubMed PMID: 30233639
Published date: 2018
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, Jun G, Kunkle B, Kuzma A, Lee JJ, Lunetta KL, Ma Y, Martin E, Naj A, Nato AQ, Navas P, Nguy
Dementia and geriatric cognitive disorders 45 (1-2):1-17. PubMed PMID: 29486463
Published date: 2018
Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly.
Lee S, Zhou X, Gao Y, Vardarajan B, Reyes-Dumeyer D, Rajan KB, Wilson RS, Evans DA, Besser LM, Kukull WA, Bennett DA, Brickman AM, Schupf N, Mayeux R, Barral S
PloS one 13 (11):e0206803. PubMed PMID: 30462667
Published date: 2018
Best practices and lessons learned from reuse of 4 patient-derived metabolomics datasets in Alzheimer's disease.
Tenenbaum JD, Blach C
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. PubMed PMID: 29218889
Published date: 2018
Population Neuroscience: Dementia Epidemiology Serving Precision Medicine and Population Health.
Ganguli M, Albanese E, Seshadri S, Bennett DA, Lyketsos C, Kukull WA, Skoog I, Hendrie HC
Alzheimer disease and associated disorders 32 (1):1-9. PubMed PMID: 29319603
Published date: 2018 Jan-Mar
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
Peloso GM, van der Lee SJ, Destefano AL, Seshardi S
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 30422133
Published date: 2018
MIND Diet Associated with Reduced Incidence and Delayed Progression of ParkinsonismA in Old Age.
Agarwal P, Wang Y, Buchman AS, Holland TM, Bennett DA, Morris MC
The journal of nutrition, health & aging 22 (10):1211-1215. PubMed PMID: 30498828
Published date: 2018
The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia.
Tasaki S, Gaiteri C, Mostafavi S, De Jager PL, Bennett DA
Frontiers in neuroscience. PubMed PMID: 30349450
Published date: 2018
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.
Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eri
Psychosomatic medicine 80 (3):242-251. PubMed PMID: 29280852
Published date: 2017 Dec 27
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM
Science translational medicine. PubMed PMID: 29263232
Published date: 2017 Dec 20
Nutrients and bioactives in green leafy vegetables and cognitive decline: Prospective study.
Morris MC, Wang Y, Barnes LL, Bennett DA, Dawson-Hughes B, Booth SL
Neurology 90 (3):e214-e222. PubMed PMID: 29263222
Published date: 2017 Dec 20
Ex-vivo quantitative susceptibility mapping of human brain hemispheres.
Evia AM, Kotrotsou A, Tamhane AA, Dawe RJ, Kapasi A, Leurgans SE, Schneider JA, Bennett DA, Arfanakis K
PloS one 12 (12):e0188395. PubMed PMID: 29261693
Published date: 2017
Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.
Peera Kommaddi R, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, Shaw E, Bennett DA, Nair D, Ravindranath V
The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (5):1085-1099. PubMed PMID: 29246925
Published date: 2017 Dec 15
Person-specific contribution of neuropathologies to cognitive loss in old age.
Boyle PA, Yu L, Wilson RS, Leurgans SE, Schneider JA, Bennett DA
Annals of neurology 83 (1):74-83. PubMed PMID: 29244218
Published date: 2017 Dec 15
Inventory of real world data sources in Parkinson's disease.
Tanguy A, Jo?nsson L, Ishihara L
BMC neurology 17 (1):213. PubMed PMID: 29216834
Published date: 2017 Dec 08
A variant in PPP4R3A protects against alzheimer-related metabolic decline.
Christopher L, Napolioni V, Khan RR, Han SS, Greicius MD
Annals of neurology 82 (6):900-911. PubMed PMID: 29130521
Published date: 2017 Dec
Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study.
Klaver AC, Coffey MP, Bennett DA, Loeffler DA
Translational neurodegeneration. PubMed PMID: 29204273
Published date: 2017
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan
Acta neuropathologica 135 (1):85-93. PubMed PMID: 29177679
Published date: 2017 Nov 24
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL
Stem cell reports 9 (6):1868-1884. PubMed PMID: 29153990
Published date: 2017 Nov 13
Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA
JAMA neurology 74 (12):1473-1480. PubMed PMID: 29084334
Published date: 2017 Oct 30
Sleep fragmentation and Parkinson's disease pathology in older adults without Parkinson's disease.
Sohail S, Yu L, Schneider JA, Bennett DA, Buchman AS, Lim ASP
Movement disorders : official journal of the Movement Disorder Society 32 (12):1729-1737. PubMed PMID: 29082554
Published date: 2017 Oct 30
Fish Intake, Genetic Predisposition to Alzheimer Disease, and Decline in Global Cognition and Memory in 5 Cohorts of Older Persons.
Samieri C, Morris MC, Bennett DA, Berr C, Amouyel P, Dartigues JF, Tzourio C, Chasman DI, Grodstein F
American journal of epidemiology 187 (5):933-940. PubMed PMID: 29053784
Published date: 2017 Oct 19
Genetic influence of plasma homocysteine on Alzheimer's disease.
Roostaei T, Felsky D, Nazeri A, De Jager PL, Schneider JA, Bennett DA, Voineskos AN
Neurobiology of aging. PubMed PMID: 29102475
Published date: 2017 Oct 13
Traumatic brain injury may not increase the risk of Alzheimer disease.
Weiner MW, Crane PK, Montine TJ, Bennett DA, Veitch DP
Neurology 89 (18):1923-1925. PubMed PMID: 28978654
Published date: 2017 Oct 04
Ultra-rare mutations in
Vardarajan BN, Tosto G, Lefort R, Yu L, Bennett DA, De Jager PL, Barral S, Reyes-Dumeyer D, Nagy PL, Lee JH, Cheng R, Medrano M, Lantigua R, Rogaeva E, St George-Hyslop P, Mayeux R
Neurology. Genetics 3 (5):e178. PubMed PMID: 28852706
Published date: 2017 Oct
Spinal Lewy body pathology in older adults without an antemortem diagnosis of Parkinson's disease.
Buchman AS, Nag S, Leurgans SE, Miller J, VanderHorst VGJM, Bennett DA, Schneider JA
Brain pathology (Zurich, Switzerland) 28 (4):560-568. PubMed PMID: 28960595
Published date: 2017 Sep 28
Spinal Arteriolosclerosis Is Common in Older Adults and Associated With Parkinsonism.
Buchman AS, Leurgans SE, Nag S, VanderHorst VGJM, Kapasi A, Schneider JA, Bennett DA
Stroke 48 (10):2792-2798. PubMed PMID: 28931619
Published date: 2017 Sep 20
Age and the association of dementia-related pathology with trajectories of cognitive decline.
Jansen WJ, Wilson RS, Visser PJ, Nag S, Schneider JA, James BD, Leurgans SE, Capuano AW, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29078129
Published date: 2017 Sep 05
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
Ng B, White CC, Klein HU, Sieberts SK, McCabe C, Patrick E, Xu J, Yu L, Gaiteri C, Bennett DA, Mostafavi S, De Jager PL
Nature neuroscience 20 (10):1418-1426. PubMed PMID: 28869584
Published date: 2017 Sep 04
Body Mass Index and Decline in Cognitive Function in Older Black and White Persons.
Arvanitakis Z, Capuano AW, Bennett DA, Barnes LL
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (2):198-203. PubMed PMID: 28961897
Published date: 2017 Aug 07
UNC5C variants are associated with cerebral amyloid angiopathy.
Yang HS, White CC, Chibnik LB, Klein HU, Schneider JA, Bennett DA, De Jager PL
Neurology. Genetics 3 (4):e176. PubMed PMID: 28761931
Published date: 2017 Aug
Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Zillikens MC, Demissie S, Hsu YH, Yerges-Armstrong LM, Chou WC, Stolk L, Livshits G, Broer L, Johnson T, Koller DL, Kutalik Z, Luan J, Malkin I, Ried JS, Smith AV, Thorleifsson G, Vandenput L, Hua Zhao J, Zhang W, Aghdassi A, A?kesson K, Amin N, Baier LJ,
Nature communications 8 (1):80. PubMed PMID: 28724990
Published date: 2017 Jul 19
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P,
Nature genetics 49 (9):1373-1384. PubMed PMID: 28714976
Published date: 2017 Jul 17
APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Yang J, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
PloS one 12 (7):e0180356. PubMed PMID: 28672022
Published date: 2017
Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
Patrick E, Rajagopal S, Wong HA, McCabe C, Xu J, Tang A, Imboywa SH, Schneider JA, Pochet N, Krichevsky AM, Chibnik LB, Bennett DA, De Jager PL
Molecular neurodegeneration 12 (1):51. PubMed PMID: 28668092
Published date: 2017 Jul 01
Purpose in Life and Hospitalization for Ambulatory Care-Sensitive Conditions in Old Age.
Wilson RS, Capuano AW, James BD, Amofa P, Arvanitakis Z, Shah R, Bennett DA, Boyle PA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 26 (3):364-374. PubMed PMID: 28780129
Published date: 2017 Jun 30
Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 9 (12):430. PubMed PMID: 28624335
Published date: 2017 Jun 15
A translational approach to capture gait signatures of neurological disorders in mice and humans.
Broom L, Ellison BA, Worley A, Wagenaar L, So?rberg E, Ashton C, Bennett DA, Buchman AS, Saper CB, Shih LC, Hausdorff JM, VanderHorst VG
Scientific reports 7 (1):3225. PubMed PMID: 28607434
Published date: 2017 Jun 12
Decline in Literacy and Incident AD Dementia Among Community-Dwelling Older Persons.
Yu L, Wilson RS, Han SD, Leurgans S, Bennett DA, Boyle PA
Journal of aging and health 30 (9):898264317716361. PubMed PMID: 28645223
Published date: 2017 Jun 01
A Dopamine Receptor genetic variant enhances perceptual speed in cognitive healthy subjects.
Barral S, Habeck C, Gazes E, De Jager PL, Bennett DA, Stern Y
Alzheimer's & dementia (New York, N. Y.) 3 (2):254-261. PubMed PMID: 28993814
Published date: 2017 Jun
How Does Psychosocial Behavior Contribute to Cognitive Health in Old Age?
Wilson RS, Bennett DA
Brain sciences. PubMed PMID: 28545247
Published date: 2017 May 23
Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.
Lu AT, Hannon E, Levine ME, Crimmins EM, Lunnon K, Mill J, Geschwind DH, Horvath S
Nature communications. PubMed PMID: 28516910
Published date: 2017 05 18
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemensc
Acta neuropathologica 133 (5):839-856. PubMed PMID: 28247064
Published date: 2017 May
Expanding the Toolkit for Studies of Aging.
Buchman AS, Boyle PA, Bennett DA
The journal of prevention of Alzheimer's disease 4 (2):69-70. PubMed PMID: 29177136
Published date: 2017
Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
Lim AS, Klein HU, Yu L, Chibnik LB, Ali S, Xu J, Bennett DA, De Jager PL
Nature communications. PubMed PMID: 28368004
Published date: 2017 Apr 03
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL
PLoS medicine 14 (4):e1002287. PubMed PMID: 28441426
Published date: 2017 Apr
Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.
Yu L, Dawe RJ, Buchman AS, Boyle PA, Schneider JA, Arfanakis K, Bennett DA
Behavioural brain research 322 (Pt B):233-240. PubMed PMID: 27596378
Published date: 2017 Mar 30
Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
Chibnik LB, White CC, Mukherjee S, Raj T, Yu L, Larson EB, Montine TJ, Keene CD, Sonnen J, Schneider JA, Crane PK, Shulman JM, Bennett DA, De Jager PL
Molecular psychiatry 23 (6):1521-1529. PubMed PMID: 28322283
Published date: 2017 Mar 21
Decreased cortical FADD protein is associated with clinical dementia and cognitive decline in an elderly community sample.
Ramos-Miguel A, Garci?a-Sevilla JA, Barr AM, Bayer TA, Falkai P, Leurgans SE, Schneider JA, Bennett DA, Honer WG, Garci?a-Fuster MJ
Molecular neurodegeneration 12 (1):26. PubMed PMID: 28320441
Published date: 2017 Mar 20
Genetic epistasis regulates amyloid deposition in resilient aging.
Felsky D, Xu J, Chibnik LB, Schneider JA, Knight J, Kennedy JL, Bennett DA, De Jager PL, Voineskos AN
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (10):1107-1116. PubMed PMID: 28322202
Published date: 2017 Mar 17
Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery.
Bennett DA
PLoS medicine 14 (3):e1002256. PubMed PMID: 28291788
Published date: 2017 Mar
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Va
PLoS medicine 14 (3):e1002258. PubMed PMID: 28323831
Published date: 2017 03
Author response: Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Bennett DA
Neurology 88 (9):920. PubMed PMID: 28242853
Published date: 2017 Feb 28
Author response: Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Bennett DA
Neurology 88 (9):919-920. PubMed PMID: 28242851
Published date: 2017 Feb 28
Outcomes after diagnosis of mild cognitive impairment in a large autopsy series.
Abner EL, Kryscio RJ, Schmitt FA, Fardo DW, Moga DC, Ighodaro ET, Jicha GA, Yu L, Dodge HH, Xiong C, Woltjer RL, Schneider JA, Cairns NJ, Bennett DA, Nelson PT
Annals of neurology 81 (4):549-559. PubMed PMID: 28224671
Published date: 2017 Feb 22
Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease.
Geifman N, Brinton RD, Kennedy RE, Schneider LS, Butte AJ
Alzheimer's research & therapy 9 (1):10. PubMed PMID: 28212683
Published date: 2017 Feb 17
TOMM40'523 variant and cognitive decline in older persons with APOE ?3/3 genotype.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
Neurology 88 (7):661-668. PubMed PMID: 28108637
Published date: 2017 Feb 14
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (7):727-738. PubMed PMID: 28183528
Published date: 2017 Feb 06
Walking Pace and the Risk of Cognitive Decline and Dementia in Elderly Populations: A Meta-analysis of Prospective Cohort Studies.
Quan M, Xun P, Chen C, Wen J, Wang Y, Wang R, Chen P, He K
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (2):266-270. PubMed PMID: 27927757
Published date: 2017 02
Genetic architecture of age-related cognitive decline in African Americans.
Raj T, Chibnik LB, McCabe C, Wong A, Replogle JM, Yu L, Gao S, Unverzagt FW, Stranger B, Murrell J, Barnes L, Hendrie HC, Foroud T, Krichevsky A, Bennett DA, Hall KS, Evans DA, De Jager PL
Neurology. Genetics 3 (1):e125. PubMed PMID: 28078323
Published date: 2017 Feb
Novel genetic loci associated with hippocampal volume.
Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivie?res S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Be
Nature communications. PubMed PMID: 28098162
Published date: 2017 Jan 18
TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD.
Nag S, Yu L, Wilson RS, Chen EY, Bennett DA, Schneider JA
Neurology 88 (7):653-660. PubMed PMID: 28087828
Published date: 2017 Jan 13
Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline.
Boyle PA, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Wilson RS, Bennett DA
Brain : a journal of neurology 140 (3):804-812. PubMed PMID: 28082297
Published date: 2017 Jan 12
The complex genetics of gait speed: genome-wide meta-analysis approach.
Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JA, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, P
Aging 9 (1):209-246. PubMed PMID: 28077804
Published date: 2017 Jan 10
A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
Zhao J, Zhu Y, Yang J, Li L, Wu H, De Jager PL, Jin P, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):674-688. PubMed PMID: 28089213
Published date: 2017 Jan 06
Are latent variable models preferable to composite score approaches when assessing risk factors of change? Evaluation of type-I error and statistical power in longitudinal cognitive studies.
Proust-Lima C, Philipps V, Dartigues JF, Bennett DA, Glymour MM, Jacqmin-Gadda H, Samieri C
Statistical methods in medical research 28 (7):962280217739658. PubMed PMID: 29165049
Published date: 2017 Jan 01
Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology.
Yarchoan M, James BD, Shah RC, Arvanitakis Z, Wilson RS, Schneider J, Bennett DA, Arnold SE
Journal of Alzheimer's disease : JAD 56 (2):699-706. PubMed PMID: 28035936
Published date: 2016 Dec 30
Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease.
Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye JA, Lyons DE, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA, Kryscio RJ, Abner EL
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):613-623. PubMed PMID: 28017827
Published date: 2016 Dec 23
Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.
Hill WD, Davies G, Harris SE, Hagenaars SP, Liewald DC, Penke L, Gale CR, Deary IJ
Translational psychiatry 6 (12):e980. PubMed PMID: 27959336
Published date: 2016 Dec 13
A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Carrasquillo MM, Allen M, Burgess JD, Wang X, Strickland SL, Aryal S, Siuda J, Kachadoorian ML, Medway C, Younkin CS, Nair A, Wang C, Chanana P, Serie D, Nguyen T, Lincoln S, Malphrus KG, Morgan K, Golde TE, Price ND, White CC, De Jager PL, Bennett DA, As
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):663-673. PubMed PMID: 27939925
Published date: 2016 Dec 08
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttensch?n HN, Byrne EM, B?rglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E,
Biological psychiatry 82 (5):322-329. PubMed PMID: 28049566
Published date: 2016 Dec 08
Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults.
Buchman NM, Leurgans SE, Shah RJ, VanderHorst V, Wilson RS, Bachner YG, Tanne D, Schneider JA, Bennett DA, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (9):1295-1301. PubMed PMID: 27927762
Published date: 2016 Dec 07
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteri?a ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivie?res S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Arms
Nature neuroscience 19 (12):1569-1582. PubMed PMID: 27694991
Published date: 2016 Dec
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linne?r RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonza
Nature genetics 48 (12):1591. PubMed PMID: 27898078
Published date: 2016 Nov 29
Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
Dong J, Wyss A, Yang J, Price TR, Nicolas A, Nalls M, Tranah G, Franceschini N, Xu Z, Schulte C, Alonso A, Cummings SR, Fornage M, Zaykin D, Li L, Huang X, Kritchevsky S, Liu Y, Gasser T, Wilson RS, De Jager PL, Singleton AB, Pinto JM, Harris T, Mosley TH
Molecular neurobiology 54 (10):8021-8032. PubMed PMID: 27878761
Published date: 2016 Nov 23
Genetic variants linked to education predict longevity.
Marioni RE, Ritchie SJ, Joshi PK, Hagenaars SP, Okbay A, Fischer K, Adams MJ, Hill WD, Davies G, Nagy R, Amador C, La?ll K, Metspalu A, Liewald DC, Campbell A, Wilson JF, Hayward C, Esko T, Porteous DJ, Gale CR, Deary IJ
Proceedings of the National Academy of Sciences of the United States of America 113 (47):13366-13371. PubMed PMID: 27799538
Published date: 2016 Nov 22
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1.
Cronin P, McCarthy MJ, Lim AS, Salmon DP, Galasko D, Masliah E, De Jager PL, Bennett DA, Desplats P
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):689-700. PubMed PMID: 27883893
Published date: 2016 Nov 21
Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.
Ramos-Miguel A, Sawada K, Jones AA, Thornton AE, Barr AM, Leurgans SE, Schneider JA, Bennett DA, Honer WG
Acta neuropathologica 133 (3):395-407. PubMed PMID: 27866231
Published date: 2016 Nov 19
Addendum: REST and stress resistance in ageing and Alzheimer's disease.
T L, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaia?covo MP, Yankner BA
Nature 540 (7633):470. PubMed PMID: 27851730
Published date: 2016 Nov 16
Self-Reported Sleep in Older African Americans and White Americans.
Turner AD, Lim AS, Leurgans SE, Bennett DA, Buchman AS, Barnes LL
Ethnicity & disease 26 (4):521-528. PubMed PMID: 27773979
Published date: 2016 Oct 20
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ, Haines JL
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (2):119-129. PubMed PMID: 27770636
Published date: 2016 Oct 20
Diabetes, Hemoglobin A1C, and Regional Alzheimer Disease and Infarct Pathology.
Pruzin JJ, Schneider JA, Capuano AW, Leurgans SE, Barnes LL, Ahima RS, Arnold SE, Bennett DA, Arvanitakis Z
Alzheimer disease and associated disorders 31 (1):41-47. PubMed PMID: 27755004
Published date: 2016 Oct 17
White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age.
Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA
Annals of clinical and translational neurology 3 (10):791-800. PubMed PMID: 27752514
Published date: 2016 Oct
TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
James BD, Wilson RS, Boyle PA, Trojanowski JQ, Bennett DA, Schneider JA
Brain : a journal of neurology 139 (11):2983-2993. PubMed PMID: 27694152
Published date: 2016 Sep 30
Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model.
Do Carmo S, Hanzel CE, Jacobs ML, Machnes Z, Iulita MF, Yang J, Yu L, Ducatenzeiler A, Danik M, Breuillaud LS, Bennett DA, Szyf M, Cuello AC
Scientific reports. PubMed PMID: 27681803
Published date: 2016
Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gu?mu?s? ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF,
Nature neuroscience 19 (11):1442-1453. PubMed PMID: 27668389
Published date: 2016 Sep 26
Transition Between the Timed up and Go Turn to Sit Subtasks: Is Timing Everything?
Weiss A, Mirelman A, Giladi N, Barnes LL, Bennett DA, Buchman AS, Hausdorff JM
Journal of the American Medical Directors Association 17 (9):864.e9-864.e15. PubMed PMID: 27569715
Published date: 2016 Sep 1
The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
Klein HU, Bennett DA, De Jager PL
Acta neuropathologica 132 (4):503-14. PubMed PMID: 27573688
Published date: 2016 Aug 29
Personality Polygenes, Positive Affect, and Life Satisfaction.
Weiss A, Baselmans BM, Hofer E, Yang J, Okbay A, Lind PA, Miller MB, Nolte IM, Zhao W, Hagenaars SP, Hottenga JJ, Matteson LK, Snieder H, Faul JD, Hartman CA, Boyle PA, Tiemeier H, Mosing MA, Pattie A, Davies G, Liewald DC, Schmidt R, De Jager PL, Heath A
Twin research and human genetics : the official journal of the International Society for Twin Studies 19 (5):1-11. PubMed PMID: 27546527
Published date: 2016 Aug 22
The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.
Tosto G, Bird TD, Bennett DA, Boeve BF, Brickman AM, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Graff-Radford NR, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R
JAMA neurology 73 (10):1231-1237. PubMed PMID: 27533593
Published date: 2016 Aug 15
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.
Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL
Genome biology 17 (1):171. PubMed PMID: 27511193
Published date: 2016 08 11
Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Leurgans SE, Yu L, Wilson RS, Lim AS, James BD, Shulman JM, Bennett DA
Neurology 87 (10):1036-44. PubMed PMID: 27488597
Published date: 2016 Aug 3
Reduced pCREB in Alzheimer's disease prefrontal cortex is reflected in peripheral blood mononuclear cells.
Bartolotti N, Bennett DA, Lazarov O
Molecular psychiatry 21 (9):1158-66. PubMed PMID: 27480489
Published date: 2016 Aug 2
Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, De Jager PL, Bradshaw EM
Neurology. Genetics 2 (4):e90. PubMed PMID: 27504496
Published date: 2016 Aug
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Valenca GT, Srivastava GP, Oliveira-Filho J, White CC, Yu L, Schneider JA, Buchman AS, Shulman JM, Bennett DA, De Jager PL
PloS one 11 (7):e0157452. PubMed PMID: 27458716
Published date: 2016
Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings.
Crane PK, Gibbons LE, Dams-O'Connor K, Trittschuh E, Leverenz JB, Keene CD, Sonnen J, Montine TJ, Bennett DA, Leurgans S, Schneider JA, Larson EB
JAMA neurology 73 (9):1062-9. PubMed PMID: 27400367
Published date: 2016 Jul 11
Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Farfel JM, Yu L, Buchman AS, Schneider JA, De Jager PL, Bennett DA
Neurology 87 (5):489-96. PubMed PMID: 27371493
Published date: 2016 Jul 1
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Ev
Aging cell 15 (5):792-800. PubMed PMID: 27325353
Published date: 2016 Jun 21
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.
Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF,
Journal of Alzheimer's disease : JAD 53 (3):921-32. PubMed PMID: 27340842
Published date: 2016 Jun 18
Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study.
Arvanitakis Z, Capuano AW, Leurgans SE, Bennett DA, Schneider JA
The Lancet. Neurology 15 (9):934-43. PubMed PMID: 27312738
Published date: 2016 Jun 13
Genetic variants in Alzheimer disease - molecular and brain network approaches.
Gaiteri C, Mostafavi S, Honey CJ, De Jager PL, Bennett DA
Nature reviews. Neurology 12 (7):413-27. PubMed PMID: 27282653
Published date: 2016 Jun 10
Postmortem MRI: a novel window into the neurobiology of late life cognitive decline.
Dawe RJ, Yu L, Leurgans SE, Schneider JA, Buchman AS, Arfanakis K, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 27459937
Published date: 2016 Jun 6
Association of financial and health literacy with cognitive health in old age.
Wilson RS, Yu L, James BD, Bennett DA, Boyle PA
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition 24 (2):1-12. PubMed PMID: 27263546
Published date: 2016 Jun 4
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC
PLoS biology 14 (6):e1002472. PubMed PMID: 27254664
Published date: 2016 Jun
Genome-wide association study identifies 74 loci associated with educational attainment.
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Con
Nature 533 (7604):539-42. PubMed PMID: 27225129
Published date: 2016 May 26
Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis.
Sajeev G, Weuve J, Jackson JW, VanderWeele TJ, Bennett DA, Grodstein F, Blacker D
Epidemiology (Cambridge, Mass.) 27 (5):732-42. PubMed PMID: 27227783
Published date: 2016 May 25
Associations of APOE ε4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia.
Stewart CC, Boyle PA, James BD, Yu L, Han SD, Bennett DA
The journals of gerontology. Series B, Psychological sciences and social sciences 73 (5):778-786. PubMed PMID: 27174891
Published date: 2016 May 12
APOE ε4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline.
van de Rest O, Wang Y, Barnes LL, Tangney C, Bennett DA, Morris MC
Neurology 86 (22):2063-70. PubMed PMID: 27164694
Published date: 2016 May 4
Assessment of the genetic variance of late-onset Alzheimer's disease.
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK
Neurobiology of aging. PubMed PMID: 27036079
Published date: 2016 May
The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK
Neurobiology of aging. PubMed PMID: 27103524
Published date: 2016 May
Sigmoidal mixed models for longitudinal data.
Capuano AW, Wilson RS, Leurgans SE, Dawson JD, Bennett DA, Hedeker D
Statistical methods in medical research 27 (3):863-875. PubMed PMID: 27130491
Published date: 2016 Apr 28
Response to Letter Regarding Article, "Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People".
Lim AS, Bennett DA, Buchman AS
Stroke 47 (6):e175. PubMed PMID: 27118794
Published date: 2016 Apr 26
Temporal course of neurodegenerative effects on cognition in old age.
Wilson RS, Capuano AW, Bennett DA, Schneider JA, Boyle PA
Neuropsychology 30 (5):591-9. PubMed PMID: 27111293
Published date: 2016 Apr 25
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linne?r RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonza
Nature genetics 48 (6):624-33. PubMed PMID: 27089181
Published date: 2016 Apr 18
Occupational cognitive requirements and late-life cognitive aging.
Pool LR, Weuve J, Wilson RS, Bültmann U, Evans DA, Mendes de Leon CF
Neurology 86 (15):1386-1392. PubMed PMID: 26984944
Published date: 2016 04 12
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.
Allen GI, Amoroso N, Anghel C, Balagurusamy V, Bare CJ, Beaton D, Bellotti R, Bennett DA, Boehme K, Boutros PC, Caberlotto L, Caloian C, Campbell F, Neto EC, Chang YC, Chen B, Chen CY, Chien TY, Clark T, Das S, Davatzikos C, Deng J, Dillenberger D, Dobson
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (6):645-53. PubMed PMID: 27079753
Published date: 2016 Apr 11
Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.
Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 36 (4):819-30. PubMed PMID: 26762507
Published date: 2016 Apr
Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.
Roostaei T, Nazeri A, Felsky D, De Jager PL, Schneider JA, Pollock BG, Bennett DA, Voineskos AN
Molecular psychiatry 22 (2):287-295. PubMed PMID: 27021820
Published date: 2016 Mar 29
Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.
Yu L, Chibnik L, Yang J, McCabe C, Xu J, Schneider JA, De Jager PL, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (9):942-51. PubMed PMID: 27016692
Published date: 2016 Mar 23
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.
Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, Wellmann J, Cornelis MC, Ollila HM, Yu L, Smith JA, Pilling LC, Isaacs A, Palotie A, Zhuang WV, Zonderman A, Faul JD, Sutin A, Meirelles O, Mulas A,
Psychological medicine 46 (8):1-11. PubMed PMID: 26997408
Published date: 2016 Mar 21
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T,
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (3):233-43. PubMed PMID: 26092349
Published date: 2016 Mar
Independent and interactive impacts of hypertension and diabetes mellitus on verbal memory: A coordinated analysis of longitudinal data from England, Sweden, and the United States.
Kelly A, Calamia M, Koval A, Terrera GM, Piccinin AM, Clouston S, Hassing LB, Bennett DA, Johansson B, Hofer SM
Psychology and aging 31 (3):262-73. PubMed PMID: 26913926
Published date: 2016 Feb 25
Financial literacy is associated with white matter integrity in old age.
Han SD, Boyle PA, Arfanakis K, Fleischman D, Yu L, James BD, Bennett DA
NeuroImage. PubMed PMID: 26899784
Published date: 2016 Feb 17
Assessing the genetic overlap between BMI and cognitive function.
Marioni RE, Yang J, Dykiert D, Mo?ttus R, Campbell A, Davies G, Hayward C, Porteous DJ, Visscher PM, Deary IJ
Molecular psychiatry 21 (10):1477-82. PubMed PMID: 26857597
Published date: 2016 Feb 9
The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts.
Arvanitakis Z, Capuano AW, Leurgans SE, Buchman AS, Bennett DA, Schneider JA
Brain pathology (Zurich, Switzerland) 27 (1):77-85. PubMed PMID: 26844934
Published date: 2016 Feb 4
Association of Seafood Consumption, Brain Mercury Level, and APOE ε4 Status With Brain Neuropathology in Older Adults.
Morris MC, Brockman J, Schneider JA, Wang Y, Bennett DA, Tangney CC, van de Rest O
JAMA 315 (5):489-97. PubMed PMID: 26836731
Published date: 2016 Feb 2
Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, Haines JL, Thornton-Wells TA
Neurobiology of aging. PubMed PMID: 26827652
Published date: 2016 Feb
Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.
Ebbert MTW, Boehme KL, Wadsworth ME, Staley LA, Mukherjee S, Crane PK, Ridge PG, Kauwe JSK
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (2):121-129. PubMed PMID: 26449541
Published date: 2016 Feb
Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA
Neurology 86 (8):735-41. PubMed PMID: 26819457
Published date: 2016 Jan 27
Olfactory Dysfunction in Older Adults is Associated with Feelings of Depression and Loneliness.
Sivam A, Wroblewski KE, Alkorta-Aranburu G, Barnes LL, Wilson RS, Bennett DA, Pinto JM
Chemical senses 41 (4):293-9. PubMed PMID: 26809485
Published date: 2016 Jan 24
Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.
Abner EL, Nelson PT, Kryscio RJ, Schmitt FA, Fardo DW, Woltjer RL, Cairns NJ, Yu L, Dodge HH, Xiong C, Masaki K, Tyas SL, Bennett DA, Schneider JA, Arvanitakis Z
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (8):882-9. PubMed PMID: 26812281
Published date: 2016 Jan 23
Sleep Fragmentation, Cerebral Arteriolosclerosis, and Brain Infarct Pathology in Community-Dwelling Older People.
Lim AS, Yu L, Schneider JA, Bennett DA, Buchman AS
Stroke 47 (2):516-8. PubMed PMID: 26768207
Published date: 2016 Jan 14
The Fine-Gray Model Under Interval Censored Competing Risks Data.
Li C
Journal of multivariate analysis. PubMed PMID: 26543275
Published date: 2016 Jan 01
Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.
Levine ME, Lu AT, Bennett DA, Horvath S
Aging 7 (12):1198-211. PubMed PMID: 26684672
Published date: 2015 Dec 18
Loss of Munc18-1 long splice variant in GABAergic terminals is associated with cognitive decline and increased risk of dementia in a community sample.
Ramos-Miguel A, Hercher C, Beasley CL, Barr AM, Bayer TA, Falkai P, Leurgans SE, Schneider JA, Bennett DA, Honer WG
Molecular neurodegeneration 10 (1):65. PubMed PMID: 26628003
Published date: 2015
Identifying the Association Between Alzheimer's Disease and Parkinson's Disease Using Genome-Wide Association Studies and Protein-Protein Interaction Network.
Liu G, Bao X, Jiang Y, Liao M, Jiang Q, Feng R, Zhang L, Ma G, Chen Z, Wang G, Wang R, Zhao B, Li K
Molecular neurobiology 52 (3):1629-1636. PubMed PMID: 25370933
Published date: 2015 Dec
Antihypertensive and Statin Medication Use and Motor Function in Community-Dwelling Older Adults.
Perlman A, Shah RC, Bennett DA, Buchman AS, Matok I
Journal of the American Medical Directors Association 17 (3):220-224. PubMed PMID: 26597419
Published date: 2015 Nov 17
Examination of the Factor Structure of a Global Cognitive Function Battery across Race and Time.
Barnes LL, Yumoto F, Capuano A, Wilson RS, Bennett DA, Tractenberg RE
Journal of the International Neuropsychological Society : JINS 22 (1):1-10. PubMed PMID: 26563713
Published date: 2015 Nov 13
Change in Cognitive Abilities in Older Latinos.
Wilson RS, Capuano AW, Marquez DX, Amofa P, Barnes LL, Bennett DA
Journal of the International Neuropsychological Society : JINS 22 (1):1-8. PubMed PMID: 26553103
Published date: 2015 Nov 10
Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons.
Boyle PA, Yu L, Nag S, Leurgans S, Wilson RS, Bennett DA, Schneider JA
Neurology 85 (22):1930-6. PubMed PMID: 26537052
Published date: 2015 Nov 4
Aging and Financial Decision Making.
Gamble K, Boyle P, Yu L, Bennett D
Management science 61 (11):2603-2610. PubMed PMID: 26622068
Published date: 2015 Nov
Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.
Dong J, Yang J, Tranah G, Franceschini N, Parimi N, Alkorta-Aranburu G, Xu Z, Alonso A, Cummings SR, Fornage M, Huang X, Kritchevsky S, Liu Y, London S, Niu L, Wilson RS, De Jager PL, Yu L, Singleton AB, Harris T, Mosley TH, Pinto JM, Bennett DA, Chen H
Medicine 94 (47):e1892. PubMed PMID: 26632684
Published date: 2015 Nov
Mild Cognitive Impairment and Susceptibility to Scams in Old Age.
Han SD, Boyle PA, James BD, Yu L, Bennett DA
Journal of Alzheimer's disease : JAD 49 (3):845-51. PubMed PMID: 26519434
Published date: 2015 Oct 22
Author Response.
Schneider JA, Yu L, Bennett DA
Neurology 85 (15):1355. PubMed PMID: 26744756
Published date: 2015 Oct 13
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Dickson DW, Rademakers R, Nicholson AM, Schneider JA, Yu L, Bennett DA
Neurology 85 (15):1354-5. PubMed PMID: 26459943
Published date: 2015 Oct 13
Common variants in DRD2 are associated with sleep duration: the CARe consortium.
Cade BE, Gottlieb DJ, Lauderdale DS, Bennett DA, Buchman AS, Buxbaum SG, De Jager PL, Evans DS, Fu?lo?p T, Gharib SA, Johnson WC, Kim H, Larkin EK, Lee SK, Lim AS, Punjabi NM, Shin C, Stone KL, Tranah GJ, Weng J, Yaffe K, Zee PC, Patel SR, Zhu X, Red
Human molecular genetics 25 (1):167-79. PubMed PMID: 26464489
Published date: 2015 Oct 13
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpela?inen TO, Lu Y, Ma?gi R, Mihailov E, Pers TH, Ru?eger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD,
PLoS genetics 11 (10):e1005378. PubMed PMID: 26426971
Published date: 2015 Oct
CD33 modulates TREM2: convergence of Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL
Nature neuroscience 18 (11):1556-8. PubMed PMID: 26414614
Published date: 2015 Sep 28
Association of APOE with tau-tangle pathology with and without β-amyloid.
Farfel JM, Yu L, De Jager PL, Schneider JA, Bennett DA
Neurobiology of aging. PubMed PMID: 26481403
Published date: 2015 Sep 28
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC
JAMA neurology 72 (11):1313-23. PubMed PMID: 26366463
Published date: 2015 Sep 14
Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology.
Buchman AS, Wilson RS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 71 (4):549-56. PubMed PMID: 26362440
Published date: 2015 Sep 10
Quantile regression with a change-point model for longitudinal data: An application to the study of cognitive changes in preclinical alzheimer's disease.
Li C, Dowling NM, Chappell R
Biometrics 71 (3):625-35. PubMed PMID: 25892034
Published date: 2015 Sep
Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults.
Lim AS, Fleischman DA, Dawe RJ, Yu L, Arfanakis K, Buchman AS, Bennett DA
Sleep 39 (1):227-35. PubMed PMID: 26350471
Published date: 2015 Aug 31
Temporal course and pathologic basis of unawareness of memory loss in dementia.
Wilson RS, Boyle PA, Yu L, Barnes LL, Sytsma J, Buchman AS, Bennett DA, Schneider JA
Neurology 85 (11):984-91. PubMed PMID: 26311746
Published date: 2015 Aug 26
APOE and cerebral amyloid angiopathy in community-dwelling older persons.
Yu L, Boyle PA, Nag S, Leurgans S, Buchman AS, Wilson RS, Arvanitakis Z, Farfel JM, De Jager PL, Bennett DA, Schneider JA
Neurobiology of aging 36 (11):2946-53. PubMed PMID: 26341746
Published date: 2015 Aug 15
GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.
Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, McDonald BC, Yoder KK, Hutchins GD, West JD, Tallman EF, Gao S, Foroud TM, Farlow MR, De Jager PL, Bennett DA, Aisen PS, Petersen RC, Jack CR, Toga AW, Green RC, Jagust WJ, Weiner MW, Saykin AJ
Brain : a journal of neurology 138 (Pt 10):3076-3088. PubMed PMID: 26268530
Published date: 2015 Aug 11
Late-life depression is not associated with dementia-related pathology.
Wilson RS, Boyle PA, Capuano AW, Shah RC, Hoganson GM, Nag S, Bennett DA
Neuropsychology 30 (2):135-42. PubMed PMID: 26237627
Published date: 2015 Aug 3
Author response.
Verghese J, Kowal P, Bennett DA
Neurology 85 (4):389. PubMed PMID: 26436154
Published date: 2015 Jul 28
Motoric cognitive risk syndrome: multicenter incidence study.
Mahlknecht P, Kiechl S, Willeit J, Poewe W, Seppi K, Verghese J, Kowal P, Bennett DA
Neurology 85 (4):388-9. PubMed PMID: 26215881
Published date: 2015 Jul 28
GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.
Hohman TJ, Chibnik L, Bush WS, Jefferson AL, De Jaeger PL, Thornton-Wells TA, Bennett DA, Schneider JA
Neurotoxicity research 28 (3):232-8. PubMed PMID: 26194614
Published date: 2015 Jul 21
Mixed pathology is more likely in black than white decedents with Alzheimer dementia.
Barnes LL, Leurgans S, Aggarwal NT, Shah RC, Arvanitakis Z, James BD, Buchman AS, Bennett DA, Schneider JA
Neurology 85 (6):528-34. PubMed PMID: 26180136
Published date: 2015 Jul 15
Neuropathologic correlates of regional brain volumes in a community cohort of older adults.
Kotrotsou A, Schneider JA, Bennett DA, Leurgans SE, Dawe RJ, Boyle PA, Golak T, Arfanakis K
Neurobiology of aging 36 (10):2798-805. PubMed PMID: 26195068
Published date: 2015 Jun 30
Grey matter correlates of susceptibility to scams in community-dwelling older adults.
Duke Han S, Boyle PA, Yu L, Arfanakis K, James BD, Fleischman DA, Bennett DA
Brain imaging and behavior 10 (2):524-32. PubMed PMID: 26100658
Published date: 2015 Jun 23
Reply to Itzhaki.
Barnes LL, Capuano AW, Aiello AE, Turner AD, Yolken RH, Torrey EF, Bennett DA
The Journal of infectious diseases 211 (12):2024. PubMed PMID: 25635124
Published date: 2015 Jun 15
MIND diet slows cognitive decline with aging.
Morris MC, Tangney CC, Wang Y, Sacks FM, Barnes LL, Bennett DA, Aggarwal NT
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (9):1015-22. PubMed PMID: 26086182
Published date: 2015 Jun 15
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Mukherjee S, Walter S, Kauwe JS, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (12):1439-51. PubMed PMID: 26079416
Published date: 2015 Jun 12
Irregular 24-hour activity rhythms and the metabolic syndrome in older adults.
Sohail S, Yu L, Bennett DA, Buchman AS, Lim AS
Chronobiology international 32 (6):1-12. PubMed PMID: 26061588
Published date: 2015 Jun 10
Alzheimer's loci: epigenetic associations and interaction with genetic factors.
Chibnik LB, Yu L, Eaton ML, Srivastava G, Schneider JA, Kellis M, Bennett DA, De Jager PL
Annals of clinical and translational neurology 2 (6):636-47. PubMed PMID: 26125039
Published date: 2015 Jun
Discrepancies between cognition and decision making in older adults.
Han SD, Boyle PA, James BD, Yu L, Barnes LL, Bennett DA
Aging clinical and experimental research 28 (1):99-108. PubMed PMID: 25995167
Published date: 2015 May 21
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
Yang J, Yu L, Gaiteri C, Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA
The international journal of biochemistry & cell biology. PubMed PMID: 26003740
Published date: 2015 May 20
Cognitive activity, cognitive function, and brain diffusion characteristics in old age.
Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, Fleischman DA, Bennett DA
Brain imaging and behavior 10 (2):455-63. PubMed PMID: 25982658
Published date: 2015 May 16
Cognitive aging in older Black and White persons.
Wilson RS, Capuano AW, Sytsma J, Bennett DA, Barnes LL
Psychology and aging 30 (2):279-85. PubMed PMID: 25961876
Published date: 2015 May 11
Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans.
Wang JL, Lim AS, Chiang WY, Hsieh WH, Lo MT, Schneider JA, Buchman AS, Bennett DA, Hu K, Saper CB
Annals of neurology 78 (2):317-22. PubMed PMID: 25921596
Published date: 2015 Apr 29
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J, Willems
Molecular psychiatry 20 (6):735-43. PubMed PMID: 25917368
Published date: 2015 Apr 28
Poorer Financial and Health Literacy Among Community-Dwelling Older Adults With Mild Cognitive Impairment.
Han SD, Boyle PA, James BD, Yu L, Bennett DA
Journal of aging and health 27 (6):1105-17. PubMed PMID: 25903976
Published date: 2015 Apr 22
Effect of common neuropathologies on progression of late life cognitive impairment.
Yu L, Boyle PA, Leurgans S, Schneider JA, Kryscio RJ, Wilson RS, Bennett DA
Neurobiology of aging 36 (7):2225-31. PubMed PMID: 25976345
Published date: 2015 Apr 22
α-Synuclein pathology accumulates in sacral spinal visceral sensory pathways.
VanderHorst VG, Samardzic T, Saper CB, Anderson MP, Nag S, Schneider JA, Bennett DA, Buchman AS
Annals of neurology 78 (1):142-9. PubMed PMID: 25893830
Published date: 2015 Apr 20
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Sch
Molecular psychiatry 21 (2):189-97. PubMed PMID: 25869804
Published date: 2015 Apr 14
Mild cognitive impairment is associated with poorer decision-making in community-based older persons.
Han SD, Boyle PA, James BD, Yu L, Bennett DA
Journal of the American Geriatrics Society 63 (4):676-83. PubMed PMID: 25850350
Published date: 2015 Apr 6
Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment.
Arvanitakis Z, Fleischman DA, Arfanakis K, Leurgans SE, Barnes LL, Bennett DA
Brain structure & function 221 (4):2135-46. PubMed PMID: 25833685
Published date: 2015 Apr 2
Cognitive decline is associated with risk aversion and temporal discounting in older adults without dementia.
James BD, Boyle PA, Yu L, Han SD, Bennett DA
PloS one 10 (4):e0121900. PubMed PMID: 25838074
Published date: 2015
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, To?glhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikan
Neurobiology of aging 36 (4):1765.e7-16. PubMed PMID: 25670335
Published date: 2015 Apr
Dementia: Cognitive resilience in APOE*ε4 carriers—is race important?
Barnes LL, Bennett DA
Nature reviews. Neurology 11 (4):190-1. PubMed PMID: 25799927
Published date: 2015 Apr
Purpose in life and cerebral infarcts in community-dwelling older people.
Yu L, Boyle PA, Wilson RS, Levine SR, Schneider JA, Bennett DA
Stroke 46 (4):1071-6. PubMed PMID: 25791714
Published date: 2015 Mar 19
Physical activity, motor function, and white matter hyperintensity burden in healthy older adults.
Fleischman DA, Yang J, Arfanakis K, Arvanitakis Z, Leurgans SE, Turner AD, Barnes LL, Bennett DA, Buchman AS
Neurology 84 (13):1294-300. PubMed PMID: 25762710
Published date: 2015 Mar 11
Conscientiousness, dementia related pathology, and trajectories of cognitive aging.
Wilson RS, Boyle PA, Yu L, Segawa E, Sytsma J, Bennett DA
Psychology and aging 30 (1):74-82. PubMed PMID: 25664558
Published date: 2015 Mar
Variation in longevity gene KLOTHO is associated with greater cortical volumes.
Yokoyama JS, Sturm VE, Bonham LW, Klein E, Arfanakis K, Yu L, Coppola G, Kramer JH, Bennett DA, Miller BL, Dubal DB
Annals of clinical and translational neurology 2 (3):215-30. PubMed PMID: 25815349
Published date: 2015 Mar
Establishing Composite Cognitive Endpoints for Use in Preclinical Alzheimer's Disease Trials.
Langbaum JB, Hendrix S, Ayutyanont N, Bennett DA, Shah RC, Barnes LL, Lopera F, Reiman EM, Tariot PN
The journal of prevention of Alzheimer's disease 2 (1):2-3. PubMed PMID: 26273569
Published date: 2015 Mar
The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia.
Abner EL, Schmitt FA, Nelson PT, Lou W, Wan L, Gauriglia R, Dodge HH, Woltjer RL, Yu L, Bennet DA, Schneider JA, Chen R, Masaki K, Katz MJ, Lipton RB, Dickson DW, Lim KO, Hemmy LS, Cairns NJ, Grant E, Tyas SL, Xiong C, Fardo DW, Kryscio RJ
Observational studies 1 (2015):56-73. PubMed PMID: 25984574
Published date: 2015 Mar
Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease.
Nag S, Yu L, Capuano AW, Wilson RS, Leurgans SE, Bennett DA, Schneider JA
Annals of neurology 77 (6):942-52. PubMed PMID: 25707479
Published date: 2015 Feb 23
Integrative analysis of 111 reference human epigenomes.
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coar
Nature 518 (7539):317-30. PubMed PMID: 25693563
Published date: 2015 Feb 19
MIND diet associated with reduced incidence of Alzheimer's disease.
Morris MC, Tangney CC, Wang Y, Sacks FM, Bennett DA, Aggarwal NT
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (9):1007-14. PubMed PMID: 25681666
Published date: 2015 Feb 11
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Yu L, De Jager PL, Yang J, Trojanowski JQ, Bennett DA, Schneider JA
Neurology 84 (9):927-34. PubMed PMID: 25653292
Published date: 2015 Feb 4
B-lymphocyte-mediated delayed cognitive impairment following stroke.
Doyle KP, Quach LN, Sole? M, Axtell RC, Nguyen TV, Soler-Llavina GJ, Jurado S, Han J, Steinman L, Longo FM, Schneider JA, Malenka RC, Buckwalter MS
The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (5):2133-45. PubMed PMID: 25653369
Published date: 2015 Feb 04
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, Postmus I, Smith AV, Smith JA, Thalamuthu A, Thomson R, Vitart V, Wang J,
Molecular psychiatry 20 (2):183-92. PubMed PMID: 25644384
Published date: 2015 Feb 3
Relationship between Auditory and Cognitive Abilities in Older Adults.
Sheft S, Shafiro V, Wang E, Barnes LL, Shah RC
PloS one 10 (8):e0134330. PubMed PMID: 26237423
Published date: 2015
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA
The journals of gerontology. Series A, Biological sciences and medical sciences 70 (1):110-8. PubMed PMID: 25199915
Published date: 2015 Jan
Post-mortem brain pathology is related to declining respiratory function in community-dwelling older adults.
Buchman AS, Yu L, Wilson RS, Dawe RJ, VanderHorst V, Schneider JA, Bennett DA
Frontiers in aging neuroscience. PubMed PMID: 26539108
Published date: 2015
Genetic diversity is a predictor of mortality in humans.
Bihlmeyer NA, Brody JA, Smith A, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza S, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M,
BMC genetics 15 (1):1274. PubMed PMID: 25543667
Published date: 2014 Dec 29
A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.
Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL
Annals of neurology 77 (3):469-77. PubMed PMID: 25545807
Published date: 2014 Dec 26
Residual decline in cognition after adjustment for common neuropathologic conditions.
Yu L, Boyle PA, Segawa E, Leurgans S, Schneider JA, Wilson RS, Bennett DA
Neuropsychology 29 (3):335-43. PubMed PMID: 25495832
Published date: 2014 Dec 15
Negative social interactions and risk of mild cognitive impairment in old age.
Wilson RS, Boyle PA, James BD, Leurgans SE, Buchman AS, Bennett DA
Neuropsychology 29 (4):561-70. PubMed PMID: 25495828
Published date: 2014 Dec 15
Motoric cognitive risk syndrome: Multicenter incidence study.
Verghese J, Ayers E, Barzilai N, Bennett DA, Buchman AS, Holtzer R, Katz MJ, Lipton RB, Wang C
Neurology 83 (24):2278-84. PubMed PMID: 25361778
Published date: 2014 Dec 09
Brain pathology contributes to simultaneous change in physical frailty and cognition in old age.
Buchman AS, Yu L, Wilson RS, Boyle PA, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 69 (12):1536-44. PubMed PMID: 25136002
Published date: 2014 Dec
Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell
Biological psychiatry 77 (8):749-63. PubMed PMID: 25648963
Published date: 2014 Nov 25
Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets.
Gross AL, Sherva R, Mukherjee S, Newhouse S, Kauwe JS, Munsie LM, Waterston LB, Bennett DA, Jones RN, Green RC, Crane PK
Neuroepidemiology 43 (3-4):194-205. PubMed PMID: 25402421
Published date: 2014 Nov 13
FASTKD2 is associated with memory and hippocampal structure in older adults.
Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Aisen PS, Petersen RC, Jack CR, Shaw LM, Trojanowski JQ, Weiner MW, Green RC, Toga AW, De
Molecular psychiatry 20 (10):1197-204. PubMed PMID: 25385369
Published date: 2014 Nov 11
Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.
Yu L, Chibnik LB, Srivastava GP, Pochet N, Yang J, Xu J, Kozubek J, Obholzer N, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA
JAMA neurology 72 (1):15-24. PubMed PMID: 25365775
Published date: 2014 Nov 3
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.
Lim AS, Srivastava GP, Yu L, Chibnik LB, Xu J, Buchman AS, Schneider JA, Myers AJ, Bennett DA, De Jager PL
PLoS genetics 10 (11):e1004792. PubMed PMID: 25375876
Published date: 2014 Nov
Subsets of a large cognitive battery better power clinical trials on early stage Alzheimer's disease.
Xiong C, Weng H, Bennett DA, Boyle PA, Shah RC, Fague S, Hall CB, Lipton RB, Morris JC
Neuroepidemiology 43 (2):131-9. PubMed PMID: 25376544
Published date: 2014
Relation of DASH- and Mediterranean-like dietary patterns to cognitive decline in older persons.
Tangney CC, Li H, Wang Y, Barnes L, Schneider JA, Bennett DA, Morris MC
Neurology 83 (16):1410-6. PubMed PMID: 25230996
Published date: 2014 Oct 14
Relation of antiphospholipid antibodies to postmortem brain infarcts in older people.
Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Capuano AW, Yu L, Leurgans SE, Bennett DA, Levine SR
Circulation 131 (2):182-9. PubMed PMID: 25301832
Published date: 2014 Oct 9
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer
JAMA neurology 71 (11):1394-404. PubMed PMID: 25199842
Published date: 2014 Sep 8
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P
PLoS genetics 10 (9):e1004606. PubMed PMID: 25188341
Published date: 2014 Sep
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA
Annals of neurology 76 (3):379-92. PubMed PMID: 25043464
Published date: 2014 Sep
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T, Goate A, Graff-Radford NR, Kamboh MI, Kukull WA, Manly JJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (6):609-618.e11. PubMed PMID: 25172201
Published date: 2014 Aug 26
Sleep is related to neuron numbers in the ventrolateral preoptic/intermediate nucleus in older adults with and without Alzheimer's disease.
Lim AS, Ellison BA, Wang JL, Yu L, Schneider JA, Buchman AS, Bennett DA, Saper CB
Brain : a journal of neurology 137 (Pt 10):2847-2861. PubMed PMID: 25142380
Published date: 2014 Aug 20
Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition.
Fleischman DA, Leurgans S, Arfanakis K, Arvanitakis Z, Barnes LL, Boyle PA, Han SD, Bennett DA
Brain structure & function 219 (6):2029-49. PubMed PMID: 23955313
Published date: 2014 Aug 17
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissn
Nature neuroscience 17 (9):1156-63. PubMed PMID: 25129075
Published date: 2014 Aug 17
Early life instruction in foreign language and music and incidence of mild cognitive impairment.
Wilson RS, Boyle PA, Yang J, James BD, Bennett DA
Neuropsychology 29 (2):292-302. PubMed PMID: 25110933
Published date: 2014 Aug 11
Cytomegalovirus infection and risk of Alzheimer disease in older black and white individuals.
Barnes LL, Capuano AW, Aiello AE, Turner AD, Yolken RH, Torrey EF, Bennett DA
The Journal of infectious diseases 211 (2):230-7. PubMed PMID: 25108028
Published date: 2014 Aug 8
Parahippocampal white matter volume predicts Alzheimer's disease risk in cognitively normal old adults.
Stoub TR, Detoledo-Morrell L, Dickerson BC
Neurobiology of aging 35 (8):1855-61. PubMed PMID: 24656833
Published date: 2014 Aug
Clinical-pathologic study of depressive symptoms and cognitive decline in old age.
Wilson RS, Capuano AW, Boyle PA, Hoganson GM, Hizel LP, Shah RC, Nag S, Schneider JA, Arnold SE, Bennett DA
Neurology 83 (8):702-9. PubMed PMID: 25080520
Published date: 2014 Jul 30
Motoric cognitive risk syndrome: multicountry prevalence and dementia risk.
Verghese J, Annweiler C, Ayers E, Barzilai N, Beauchet O, Bennett DA, Bridenbaugh SA, Buchman AS, Callisaya ML, Camicioli R, Capistrant B, Chatterji S, De Cock AM, Ferrucci L, Giladi N, Guralnik JM, Hausdorff JM, Holtzer R, Kim KW, Kowal P, Kressig R
Neurology 83 (8):718-26. PubMed PMID: 25031288
Published date: 2014 Jul 16
At the interface of sensory and motor dysfunctions and Alzheimer's disease.
Albers MW, Gilmore GC, Kaye J, Murphy C, Wingfield A, Bennett DA, Boxer AL, Buchman AS, Cruickshanks KJ, Devanand DP, Duffy CJ, Gall CM, Gates GA, Granholm AC, Hensch T, Holtzer R, Hyman BT, Lin FR, McKee AC, Morris JC, Petersen RC, Silbert LC, Strub
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (1):70-98. PubMed PMID: 25022540
Published date: 2014 Jul 8
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, D
PloS one 9 (6):e94661. PubMed PMID: 24922517
Published date: 2014
Missense variant in TREML2 protects against Alzheimer's disease.
Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux
Neurobiology of aging 35 (6):1510.e19-26. PubMed PMID: 24439484
Published date: 2014 Jun
Epigenomics of Alzheimer's disease.
Bennett DA, Yu L, Yang J, Srivastava GP, Aubin C, De Jager PL
Translational research : the journal of laboratory and clinical medicine 165 (1):200-220. PubMed PMID: 24905038
Published date: 2014 May 16
Life extension factor klotho enhances cognition.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-O M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL, Mucke L
Cell reports 7 (4):1065-76. PubMed PMID: 24813892
Published date: 2014 May 7
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, Kawas CH, Cribbs DH, Bennett DA, Schneider JA, Larson EB, Crane PK, Valladares O, Schmitt
Acta neuropathologica 127 (6):825-43. PubMed PMID: 24770881
Published date: 2014 Apr 27
Harm avoidance is associated with progression of parkinsonism in community-dwelling older adults: a prospective cohort study.
Buchman AS, Yu L, Wilson RS, Shulman JM, Boyle PA, Bennett DA
BMC geriatrics 14 (1):54. PubMed PMID: 24754876
Published date: 2014 Apr 23
An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease.
Langbaum JB, Hendrix SB, Ayutyanont N, Chen K, Fleisher AS, Shah RC, Barnes LL, Bennett DA, Tariot PN, Reiman EM
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (6):666-74. PubMed PMID: 24751827
Published date: 2014 Apr 18
Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
Shulman JM, Yu L, Buchman AS, Evans DA, Schneider JA, Bennett DA, De Jager PL
JAMA neurology 71 (4):429-35. PubMed PMID: 24514572
Published date: 2014 Apr
REST and stress resistance in ageing and Alzheimer's disease.
Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA
Nature 507 (7493):448-54. PubMed PMID: 24670762
Published date: 2014 Mar 27
Association between performance on Timed Up and Go subtasks and mild cognitive impairment: further insights into the links between cognitive and motor function.
Mirelman A, Weiss A, Buchman AS, Bennett DA, Giladi N, Hausdorff JM
Journal of the American Geriatrics Society 62 (4):673-8. PubMed PMID: 24635699
Published date: 2014 Mar 17
Contribution of Alzheimer disease to mortality in the United States.
James BD, Leurgans SE, Hebert LE, Scherr PA, Yaffe K, Bennett DA
Neurology 82 (12):1045-50. PubMed PMID: 24598707
Published date: 2014 Mar 5
Associations of cerebrovascular and Alzheimer's disease pathology with brain atrophy.
Crystal H, Schneider J, Bennett D, Leurgans S, Levine S
Current Alzheimer research 11 (4):309-16. PubMed PMID: 24597507
Published date: 2014 Mar 2
Brain tocopherols related to Alzheimer's disease neuropathology in humans.
Morris MC, Schneider JA, Li H, Tangney CC, Nag S, Bennett DA, Honer WG, Barnes LL
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (1):32-9. PubMed PMID: 24589434
Published date: 2014 Feb 28
Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.
Bennett DA, Yu L, De Jager PL
Biochemical pharmacology 88 (4):617-630. PubMed PMID: 24508835
Published date: 2014 Feb 6
Ex vivo T2 relaxation: associations with age-related neuropathology and cognition.
Dawe RJ, Bennett DA, Schneider JA, Leurgans SE, Kotrotsou A, Boyle PA, Arfanakis K
Neurobiology of aging 35 (7):1549-61. PubMed PMID: 24582637
Published date: 2014 Feb 6
Correlates of susceptibility to scams in older adults without dementia.
James BD, Boyle PA, Bennett DA
Journal of elder abuse & neglect 26 (2):107-22. PubMed PMID: 24499279
Published date: 2014
Gene-behavior interaction of depressive symptoms and the apolipoprotein E {varepsilon}4 allele on cognitive decline.
Rajan KB, Wilson RS, Skarupski KA, Mendes de Leon CF, Evans DA
Psychosomatic medicine 76 (2):101-8. PubMed PMID: 24434953
Published date: 2014 Feb
A self-report risk index to predict occurrence of dementia in three independent cohorts of older adults: the ANU-ADRI.
Anstey KJ, Cherbuin N, Herath PM, Qiu C, Kuller LH, Lopez OL, Wilson RS, Fratiglioni L
PloS one 9 (1):e86141. PubMed PMID: 24465922
Published date: 2014
Associations between quantitative mobility measures derived from components of conventional mobility testing and Parkinsonian gait in older adults.
Buchman AS, Leurgans SE, Weiss A, Vanderhorst V, Mirelman A, Dawe R, Barnes LL, Wilson RS, Hausdorff JM, Bennett DA
PloS one 9 (1):e86262. PubMed PMID: 24465997
Published date: 2014 Jan 22
Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Rep
Vardarajan BN, Faber KM, Bird TD, Bennett DA, Rosenberg R, Boeve BF, Graff-Radford NR, Goate AM, Farlow M, Sweet RA, Lantigua R, Medrano MZ, Ottman R, Schaid DJ, Foroud TM, Mayeux R
JAMA neurology 71 (3):315-23. PubMed PMID: 24425039
Published date: 2014 Jan 13
Prevalence of mixed pathologies in the aging brain.
Rahimi J, Kovacs GG
Alzheimer's research & therapy 6 (9):82. PubMed PMID: 25419243
Published date: 2014
Correlation between visual acuity and cognitive functions.
Elyashiv SM, Shabtai EL, Belkin M
The British journal of ophthalmology 98 (1):129-32. PubMed PMID: 24169658
Published date: 2014 Jan
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.
Raj T, Ryan KJ, Replogle JM, Chibnik LB, Rosenkrantz L, Tang A, Rothamel K, Stranger BE, Bennett DA, Evans DA, De Jager PL, Bradshaw EM
Human molecular genetics 23 (10):2729-36. PubMed PMID: 24381305
Published date: 2013 Dec 30
Harm avoidance and cerebral infarction.
Wilson RS, Boyle PA, Levine SR, Yu L, Hoganson GM, Buchman AS, Schneider JA, Bennett DA
Neuropsychology 28 (2):305-11. PubMed PMID: 24364391
Published date: 2013 Dec 23
Cognitive and social lifestyle: links with neuropathology and cognition in late life.
Bennett DA, Arnold SE, Valenzuela MJ, Brayne C, Schneider JA
Acta neuropathologica 127 (1):137-50. PubMed PMID: 24356982
Published date: 2013 Dec 20
Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women.
Bove R, Secor E, Chibnik LB, Barnes LL, Schneider JA, Bennett DA, De Jager PL
Neurology 82 (3):222-9. PubMed PMID: 24336141
Published date: 2013 Dec 11
Evidence needs to be translated, whether or not it is complete.
Dacks PA, Bennett DA, Fillit HM
JAMA neurology 71 (2):137-8. PubMed PMID: 24297103
Published date: 2013 Dec 2
The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
Felsky D, Szeszko P, Yu L, Honer WG, De Jager PL, Schneider JA, Malhotra AK, Lencz T, Ikuta T, Pipitone J, Chakravarty MM, Lobaugh NJ, Mulsant BH, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN
Molecular psychiatry 19 (10):1125-32. PubMed PMID: 24166411
Published date: 2013 Oct 29
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Li
Nature genetics 45 (12):1452-8. PubMed PMID: 24162737
Published date: 2013 Oct 27
Modification of the relationship of the apolipoprotein E ε4 allele to the risk of Alzheimer disease and neurofibrillary tangle density by sleep.
Lim AS, Yu L, Kowgier M, Schneider JA, Buchman AS, Bennett DA
JAMA neurology 70 (12):1544-51. PubMed PMID: 24145819
Published date: 2013 Oct 21
TREM2 and neurodegenerative disease.
Reitz C, Mayeux R
The New England journal of medicine 369 (16):1564-5. PubMed PMID: 24131184
Published date: 2013 Oct 17
Brainstem aminergic nuclei and late-life depressive symptoms.
Wilson RS, Nag S, Boyle PA, Hizel LP, Yu L, Buchman AS, Shah RC, Schneider JA, Arnold SE, Bennett DA
JAMA psychiatry 70 (12):1320-8. PubMed PMID: 24132763
Published date: 2013 Oct 16
Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age.
Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Bennett DA
Experimental gerontology 48 (12):1489-1498. PubMed PMID: 24135750
Published date: 2013 Oct 14
Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
Yu L, Boyle PA, Leurgans S, Schneider JA, Bennett DA
Neurobiology of aging 35 (4):819-26. PubMed PMID: 24199961
Published date: 2013 Oct 9
Elevated Aβ42 in aged, non-demented individuals with cerebral atherosclerosis.
Sadleir KR, Bennett DA, Schneider JA, Vassar R
Current Alzheimer research 10 (8):785-9. PubMed PMID: 23919773
Published date: 2013 Oct
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.
Chou SH, Shulman JM, Keenan BT, Secor EA, Buchman AS, Schneider J, Bennett DA, De Jager PL
Cerebrovascular diseases (Basel, Switzerland) 36 (3):181-8. PubMed PMID: 24135527
Published date: 2013
A 2-process model for neuropathology of Alzheimer's disease.
Mungas D, Tractenberg R, Schneider JA, Crane PK, Bennett DA
Neurobiology of aging 35 (2):301-8. PubMed PMID: 24080173
Published date: 2013 Sep 27
Internet use and decision making in community-based older adults.
James BD, Boyle PA, Yu L, Bennett DA
Frontiers in psychology. PubMed PMID: 24578696
Published date: 2013
Relation of neuropathology with cognitive decline among older persons without dementia.
Boyle PA, Yu L, Wilson RS, Schneider JA, Bennett DA
Frontiers in aging neuroscience. PubMed PMID: 24058343
Published date: 2013
Cognitive frailty.
Buchman AS, Bennett DA
The journal of nutrition, health & aging 17 (9):738-9. PubMed PMID: 24154644
Published date: 2013
Systemic inflammation in non-demented elderly human subjects: brain microstructure and cognition.
Arfanakis K, Fleischman DA, Grisot G, Barth CM, Varentsova A, Morris MC, Barnes LL, Bennett DA
PloS one 8 (8):e73107. PubMed PMID: 23991174
Published date: 2013
Cognitive decline impairs financial and health literacy among community-based older persons without dementia.
Boyle PA, Yu L, Wilson RS, Segawa E, Buchman AS, Bennett DA
Psychology and aging 28 (3):614-24. PubMed PMID: 23957225
Published date: 2013 Aug 19
Total daily activity declines more rapidly with increasing age in older adults.
Buchman AS, Wilson RS, Yu L, James BD, Boyle PA, Bennett DA
Archives of gerontology and geriatrics 58 (1):74-9. PubMed PMID: 24007938
Published date: 2013 Aug 15
Charting a dynamic DNA methylation landscape of the human genome.
Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A
Nature 500 (7463):477-81. PubMed PMID: 23925113
Published date: 2013 Aug 7
Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition.
Negash S, Wilson R, Leurgans S, Wolk D, Schneider J, Buchman A, Bennett D, Arnold S
Current Alzheimer research 10 (8):844-851. PubMed PMID: 23919768
Published date: 2013 Aug 6
The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.
Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA, Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C
PLoS genetics 9 (8):e1003685. PubMed PMID: 23990795
Published date: 2013 Aug
Using a body-fixed sensor to identify subclinical gait difficulties in older adults with IADL disability: maximizing the output of the timed up and go.
Weiss A, Mirelman A, Buchman AS, Bennett DA, Hausdorff JM
PloS one 8 (7):e68885. PubMed PMID: 23922665
Published date: 2013
Very low levels of education and cognitive reserve: a clinicopathologic study.
Farfel JM, Nitrini R, Suemoto CK, Grinberg LT, Ferretti RE, Leite RE, Tampellini E, Lima L, Farias DS, Neves RC, Rodriguez RD, Menezes PR, Fregni F, Bennett DA, Pasqualucci CA, Jacob Filho W
Neurology 81 (7):650-657. PubMed PMID: 23873971
Published date: 2013 Jul 19
Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA
JAMA neurology 70 (9):1-7. PubMed PMID: 23836404
Published date: 2013 Jul 8
Life-span cognitive activity, neuropathologic burden, and cognitive aging.
Wilson RS, Boyle PA, Yu L, Barnes LL, Schneider JA, Bennett DA
Neurology 81 (4):314-21. PubMed PMID: 23825173
Published date: 2013 Jul 3
Sleep Fragmentation and the Risk of Incident Alzheimer's Disease and Cognitive Decline in Older Persons.
Lim AS, Kowgier M, Yu L, Buchman AS, Bennett DA
Sleep 36 (7):1027-1032. PubMed PMID: 23814339
Published date: 2013
Temporal Discounting Is Associated with an Increased Risk of Mortality among Community-Based Older Persons without Dementia.
Boyle PA, Yu L, Gamble KJ, Bennett DA
PloS one 8 (6):e67376. PubMed PMID: 23826281
Published date: 2013
Much of late life cognitive decline is not due to common neurodegenerative pathologies.
Boyle PA, Wilson RS, Yu L, Barr AM, Honer WG, Schneider JA, Bennett DA
Annals of neurology 74 (3):478-489. PubMed PMID: 23798485
Published date: 2013 Jun 24
Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons.
Fleischman DA, Yu L, Arfanakis K, Han SD, Barnes LL, Arvanitakis Z, Boyle PA, Bennett DA
Frontiers in aging neuroscience. PubMed PMID: 23760360
Published date: 2013
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, E
Science (New York, N.Y.) 340 (6139):1467-1471. PubMed PMID: 23722424
Published date: 2013 May 30
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A, Morris MC, Evans DA, Johnson K, Sperling RA, Schneider JA, Bennett DA, De Jager PL
Nature neuroscience 16 (7):848-50. PubMed PMID: 23708142
Published date: 2013 May 23
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R
Translational psychiatry. PubMed PMID: 23673467
Published date: 2013 May 14
APOE ε4, Alzheimer's disease pathology, cerebrovascular disease, and cognitive change over the years prior to death.
Yu L, Boyle P, Schneider JA, Segawa E, Wilson RS, Leurgans S, Bennett DA
Psychology and aging 28 (4):1015-23. PubMed PMID: 23647000
Published date: 2013 May 6
Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.
Fung WL, Naylor MG, Bennett DA, Lange C, Blacker D
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 162 (7):770-8. PubMed PMID: 23650207
Published date: 2013 May 6
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, Macdonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ,
Cell 153 (3):707-720. PubMed PMID: 23622250
Published date: 2013 Apr 25
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fa
JAMA : the journal of the American Medical Association 309 (14):1483-92. PubMed PMID: 23571587
Published date: 2013 Apr 10
An inflection point in gene discovery efforts for neurodegenerative diseases: from syndromic diagnoses toward endophenotypes and the epigenome.
De Jager PL, Bennett DA
JAMA neurology 70 (6):1-8. PubMed PMID: 23571780
Published date: 2013 Apr 9
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, L
Neuron 78 (2):256-68. PubMed PMID: 23562540
Published date: 2013 Apr 3
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M
PloS one 8 (4):e58618. PubMed PMID: 23565137
Published date: 2013
Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Lim AS, Myers AJ, Yu L, Buchman AS, Duffy JF, De Jager PL, Bennett DA
Journal of biological rhythms 28 (2):117-29. PubMed PMID: 23606611
Published date: 2013 Apr
What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function.
Hausdorff JM, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 68 (4):409-11. PubMed PMID: 23401565
Published date: 2013 Apr
Neural reserve, neuronal density in the locus ceruleus, and cognitive decline.
Wilson RS, Nag S, Boyle PA, Hizel LP, Yu L, Buchman AS, Schneider JA, Bennett DA
Neurology 80 (13):1202-8. PubMed PMID: 23486878
Published date: 2013 Mar 26
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Green RC
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (1):45-52. PubMed PMID: 23535033
Published date: 2013 Mar 24
Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease.
Ertekin-Taner N, De Jager PL, Yu L, Bennett DA
Current genetic medicine reports 1 (1):39-51. PubMed PMID: 23482655
Published date: 2013 Mar
Association of brain pathology with the progression of frailty in older adults.
Buchman AS, Yu L, Wilson RS, Schneider JA, Bennett DA
Neurology 80 (22):2055-61. PubMed PMID: 23635961
Published date: 2013 May 1
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman E
Annals of human genetics 77 (2):85-105. PubMed PMID: 23360175
Published date: 2013 Mar
Ex vivo MR volumetry of human brain hemispheres.
Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K
Magnetic resonance in medicine 71 (1):364-74. PubMed PMID: 23440751
Published date: 2013 Feb 25
The influence of cognitive decline on well-being in old age.
Wilson RS, Boyle PA, Segawa E, Yu L, Begeny CT, Anagnos SE, Bennett DA
Psychology and aging 28 (2):304-13. PubMed PMID: 23421323
Published date: 2013 Feb 18
Neuroticism modifies the association of vision impairment and cognition among community-dwelling older adults.
Gaynes BI, Shah R, Leurgans S, Bennett D
Neuroepidemiology 40 (2):142-6. PubMed PMID: 23221773
Published date: 2013
Genome-wide chromatin state transitions associated with developmental and environmental cues.
Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE
Cell 152 (3):642-54. PubMed PMID: 23333102
Published date: 2013 Jan 31
Microvascular brain pathology and late-life motor impairment.
Buchman AS, Yu L, Boyle PA, Levine SR, Nag S, Schneider JA, Bennett DA
Neurology 80 (8):712-8. PubMed PMID: 23365057
Published date: 2013 Jan 30
Poor decision making is associated with an increased risk of mortality among community-dwelling older persons without dementia.
Boyle PA, Wilson RS, Yu L, Buchman AS, Bennett DA
Neuroepidemiology 40 (4):247-252. PubMed PMID: 23364306
Published date: 2013 Jan 24
Apolipoprotein E and change in episodic memory in blacks and whites.
Barnes LL, Arvanitakis Z, Yu L, Kelly J, De Jager PL, Bennett DA
Neuroepidemiology 40 (3):211-219. PubMed PMID: 23364031
Published date: 2013 Jan 24
A genome-wide association study of depressive symptoms.
Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Ge
Biological psychiatry 73 (7):667-78. PubMed PMID: 23290196
Published date: 2013 Jan 2
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
Whitcomb DC, Larusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Albert MS, Albin RL, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barnes LL, Beach TG, Beecham GW, Beekly D, B
Nature genetics 44 (12):1349-54. PubMed PMID: 23143602
Published date: 2012 Nov 11
Functional connectivity networks associated with chronic musculoskeletal pain in old age.
Duke Han S, Buchman AS, Arfanakis K, Fleischman DA, Bennett DA
International journal of geriatric psychiatry 28 (8):858-67. PubMed PMID: 23124844
Published date: 2012 Nov 5
Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study.
Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR
Neuroepidemiology 40 (2):73-84. PubMed PMID: 23095514
Published date: 2012 Oct 24
Association of total daily physical activity with disability in community-dwelling older persons: a prospective cohort study.
Shah RC, Buchman AS, Leurgans S, Boyle PA, Bennett DA
BMC geriatrics 12 (1):63. PubMed PMID: 23072476
Published date: 2012 Oct 16
Locus coeruleus neuron density and parkinsonism in older adults without Parkinson's disease.
Buchman AS, Nag S, Shulman JM, Lim AS, Vanderhorst VG, Leurgans SE, Schneider JA, Bennett DA
Movement disorders : official journal of the Movement Disorder Society 27 (13):1625-31. PubMed PMID: 23038629
Published date: 2012 Oct 4
GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.
Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Trojanowski JQ, Schellenberg GD, Yearout D, Huston
Neurology 79 (19):1944-1950. PubMed PMID: 23035075
Published date: 2012 Oct 3
Relation of neuropathology to cognition in persons without cognitive impairment.
Bennett DA, Wilson RS, Boyle PA, Buchman AS, Schneider JA
Annals of neurology 72 (4):599-609. PubMed PMID: 23109154
Published date: 2012 Oct
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies.
Schneider JA, Arvanitakis Z, Yu L, Boyle PA, Leurgans SE, Bennett DA
Brain : a journal of neurology 135 (Pt 10):3005-14. PubMed PMID: 23065790
Published date: 2012 Oct
Emotional neglect in childhood and cerebral infarction in older age.
Wilson RS, Boyle PA, Levine SR, Yu L, Anagnos SE, Buchman AS, Schneider JA, Bennett DA
Neurology 79 (15):1534-9. PubMed PMID: 22993291
Published date: 2012 Sep 19
Total daily physical activity and the risk of AD and cognitive decline in older adults.
Abe K, Buchman AS, Yu L, Boyle PA, Wilson RS, Bennett DA
Neurology 79 (10):1071. PubMed PMID: 22946116
Published date: 2012 Sep 4
The natural history of cognitive decline in Alzheimer's disease.
Wilson RS, Segawa E, Boyle PA, Anagnos SE, Hizel LP, Bennett DA
Psychology and aging 27 (4):1008-17. PubMed PMID: 22946521
Published date: 2012 Sep 3
A common polymorphism near PER1 and the timing of human behavioral rhythms.
Lim AS, Chang AM, Shulman JM, Raj T, Chibnik LB, Cain SW, Rothamel K, Benoist C, Myers AJ, Czeisler CA, Buchman AS, Bennett DA, Duffy JF, Saper CB, De Jager PL
Annals of neurology 72 (3):324-34. PubMed PMID: 23034908
Published date: 2012 Sep
Association of cognition with temporal discounting in community based older persons.
Boyle PP, Yu L, Wilson RS, Buchman AS, Laibson D, Bennett DA
BMC geriatrics 12 (1):48. PubMed PMID: 22938391
Published date: 2012 Aug 31
High CRP with "normal" cognition: a resilient phenotype in old age.
Buchman AS, Bennett DA
Neurology 79 (11):1078-9. PubMed PMID: 22895579
Published date: 2012 Aug 15
Association of lower hemoglobin level and neuropathology in community-dwelling older persons.
Shah RC, Schneider JA, Leurgans S, Bennett DA
Journal of Alzheimer's disease : JAD 32 (3):579-86. PubMed PMID: 22869465
Published date: 2012 Aug 2
Reply.
Buchman AS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA
Annals of neurology 72 (2):298. PubMed PMID: 22926865
Published date: 2012 Aug
Age-related changes in the mesial temporal lobe: the parahippocampal white matter region.
Stoub TR, Barnes CA, Shah RC, Stebbins GT, Ferrari C, deToledo-Morrell L
Neurobiology of aging 33 (7):1168-76. PubMed PMID: 21459484
Published date: 2012 Jul
Longitudinal epidemiologic clinical-pathologic studies of aging and Alzheimer's disease.
Bennett DA, Launer LJ
Current Alzheimer research 9 (6):617-20. PubMed PMID: 22715984
Published date: 2012 Jul
The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia.
Barnes LL, Shah RC, Aggarwal NT, Bennett DA, Schneider JA
Current Alzheimer research 9 (6):734-45. PubMed PMID: 22471868
Published date: 2012 Jul
Overview and findings from the rush Memory and Aging Project.
Bennett DA, Schneider JA, Buchman AS, Barnes LL, Boyle PA, Wilson RS
Current Alzheimer research 9 (6):646-63. PubMed PMID: 22471867
Published date: 2012 Jul
TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease.
Valant V, Keenan BT, Anderson CD, Shulman JM, Devan WJ, Ayres AM, Schwab K, Goldstein JN, Viswanathan A, Greenberg SM, Bennett DA, De Jager PL, Rosand J, Biffi A
Translational stroke research 3 (Suppl 1):102-12. PubMed PMID: 24323865
Published date: 2012 Jul
Total daily activity measured with actigraphy and motor function in community-dwelling older persons with and without dementia.
James BD, Boyle PA, Bennett DA, Buchman AS
Alzheimer disease and associated disorders 26 (3):238-45. PubMed PMID: 21946015
Published date: 2012 Jul-Sep
The impact of health and financial literacy on decision making in community-based older adults.
James BD, Boyle PA, Bennett JS, Bennett DA
Gerontology 58 (6):531-9. PubMed PMID: 22739454
Published date: 2012 Jun 22
Correlates of health and financial literacy in older adults without dementia.
Bennett JS, Boyle PA, James BD, Bennett DA
BMC geriatrics 12 (1):30. PubMed PMID: 22691341
Published date: 2012 Jun 12
Association between cognitive activity and cognitive function in older Hispanics.
Marquine MJ, Segawa E, Wilson RS, Bennett DA, Barnes LL
Journal of the International Neuropsychological Society : JINS 18 (6):1-11. PubMed PMID: 22676914
Published date: 2012 Jun 8
Selected findings from the Religious Orders Study and Rush Memory and Aging Project.
Bennett DA, Wilson RS, Arvanitakis Z, Boyle PA, de Toledo-Morrell L, Schneider JA
Journal of Alzheimer's disease : JAD 33 (0):S397-403. PubMed PMID: 22647261
Published date: 2012 May 29
Dementia from Alzheimer disease and mixed pathologies in the oldest old.
James BD, Bennett DA, Boyle PA, Leurgans S, Schneider JA
JAMA 307 (17):1798-800. PubMed PMID: 22550192
Published date: 2012 May 2
Common variants at 12q14 and 12q24 are associated with hippocampal volume.
Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA
Nature genetics 44 (5):545-51. PubMed PMID: 22504421
Published date: 2012 May
Effect of purpose in life on the relation between Alzheimer disease pathologic changes on cognitive function in advanced age.
Boyle PA, Buchman AS, Wilson RS, Yu L, Schneider JA, Bennett DA
Archives of general psychiatry 69 (5):499-505. PubMed PMID: 22566582
Published date: 2012 May
Relation of driving status to incident life space constriction in community-dwelling older persons: a prospective cohort study.
Shah RC, Maitra K, Barnes LL, James BD, Leurgans S, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 67 (9):984-9. PubMed PMID: 22546958
Published date: 2012 Apr 30
Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y, Wilson RS, Foroud T, Ott J, Mayeux R
Neurology 78 (19):1464-1471. PubMed PMID: 22539578
Published date: 2012 Apr 25
Total daily physical activity and the risk of AD and cognitive decline in older adults.
Buchman AS, Boyle PA, Yu L, Shah RC, Wilson RS, Bennett DA
Neurology 78 (17):1323-9. PubMed PMID: 22517108
Published date: 2012 Apr 18
Influence of late-life cognitive activity on cognitive health.
Wilson RS, Segawa E, Boyle PA, Bennett DA
Neurology 78 (15):1123-9. PubMed PMID: 22491864
Published date: 2012 Apr 10
Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
Raj T, Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, De Jager PL
American journal of human genetics 90 (4):720-6. PubMed PMID: 22482808
Published date: 2012 Apr 6
Perceived discrimination and cognition in older African Americans.
Barnes LL, Lewis TT, Begeny CT, Yu L, Bennett DA, Wilson RS
Journal of the International Neuropsychological Society : JINS 18 (5):1-10. PubMed PMID: 22595035
Published date: 2012 May 18
Total daily physical activity and longevity in old age.
Buchman AS, Yu L, Boyle PA, Shah RC, Bennett DA
Archives of internal medicine 172 (5):444-6. PubMed PMID: 22412115
Published date: 2012 Mar 12
Cerebral microinfarcts: the invisible lesions.
Smith EE, Schneider JA, Wardlaw JM, Greenberg SM
The Lancet. Neurology 11 (3):272-82. PubMed PMID: 22341035
Published date: 2012 Mar
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline.
Keenan BT, Shulman JM, Chibnik LB, Raj T, Tran D, Sabuncu MR, Allen AN, Corneveaux JJ, Hardy JA, Huentelman MJ, Lemere CA, Myers AJ, Nicholson-Weller A, Reiman EM, Evans DA, Bennett DA, De Jager PL
Human molecular genetics 21 (10):2377-2388. PubMed PMID: 22343410
Published date: 2012 Feb 17
Neural intrinsic connectivity networks associated with risk aversion in old age.
Han SD, Boyle PA, Arfanakis K, Fleischman DA, Yu L, Edmonds EC, Bennett DA
Behavioural brain research 227 (1):233-40. PubMed PMID: 22044475
Published date: 2012 Feb 1
Nigral pathology and parkinsonian signs in elders without Parkinson disease.
Buchman AS, Shulman JM, Nag S, Leurgans SE, Arnold SE, Morris MC, Schneider JA, Bennett DA
Annals of neurology 71 (2):258-66. PubMed PMID: 22367997
Published date: 2012 Feb
Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.
Biffi A, Shulman JM, Jagiella JM, Cortellini L, Ayres AM, Schwab K, Brown DL, Silliman SL, Selim M, Worrall BB, Meschia JF, Slowik A, De Jager PL, Greenberg SM, Schneider JA, Bennett DA, Rosand J
Neurology 78 (5):334-41. PubMed PMID: 22262751
Published date: 2012 Jan 31
Neuroticism, Extraversion, and Motor Function in Community-Dwelling Older Persons.
Buchman AS, Boyle PA, Wilson RS, Leurgans SE, Arnold SE, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 78 (5):334-41. PubMed PMID: 22237249
Published date: 2012 Jan 10
A random change point model for cognitive decline in Alzheimer's disease and mild cognitive impairment.
Yu L, Boyle P, Wilson RS, Segawa E, Leurgans S, De Jager PL, Bennett DA
Neuroepidemiology 39 (2):73-83. PubMed PMID: 22814083
Published date: 2012
Cognitive reserve, presynaptic proteins and dementia in the elderly.
Honer WG, Barr AM, Sawada K, Thornton AE, Morris MC, Leurgans SE, Schneider JA, Bennett DA
Translational psychiatry. PubMed PMID: 22832958
Published date: 2012
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Perica
PLoS genetics 8 (6):e1002707. PubMed PMID: 22685416
Published date: 2012
Functional connectivity variations in mild cognitive impairment: associations with cognitive function.
Han SD, Arfanakis K, Fleischman DA, Leurgans SE, Tuminello ER, Edmonds EC, Bennett DA
Journal of the International Neuropsychological Society : JINS 18 (1):39-48. PubMed PMID: 22005016
Published date: 2012 Jan
Increased fragmentation of rest-activity patterns is associated with a characteristic pattern of cognitive impairment in older individuals.
Lim AS, Yu L, Costa MD, Leurgans SE, Buchman AS, Bennett DA, Saper CB
Sleep 35 (5):633-40. PubMed PMID: 22547889
Published date: 2012
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.
Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, Trojanowski JQ, Vinters HV, Montine TJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 8 (1):1-13. PubMed PMID: 22265587
Published date: 2012 Jan
Risk Aversion is Associated with Decision Making among Community-Based Older Persons.
Boyle PA, Yu L, Buchman AS, Bennett DA
Frontiers in psychology. PubMed PMID: 22754545
Published date: 2012
Poor decision making is a consequence of cognitive decline among older persons without Alzheimer's disease or mild cognitive impairment.
Boyle PA, Yu L, Wilson RS, Gamble K, Buchman AS, Bennett DA
PloS one 7 (8):e43647. PubMed PMID: 22916287
Published date: 2012
Plasma and brain fatty acid profiles in mild cognitive impairment and Alzheimer's disease.
Cunnane SC, Schneider JA, Tangney C, Tremblay-Mercier J, Fortier M, Bennett DA, Morris MC
Journal of Alzheimer's disease : JAD 29 (3):691-7. PubMed PMID: 22466064
Published date: 2012 Jan 1
The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease.
Yu L, Shulman JM, Chibnik L, Leurgans S, Schneider JA, De Jager PL, Bennett DA
Aging cell 11 (2):228-233. PubMed PMID: 22122979
Published date: 2011 Nov 28
A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ, Rosand J, Daly MJ, Myers AJ, Reiman EM, Bennett DA, Evans DA
Neurobiology of aging 33 (5):1017.e1-1017.e15. PubMed PMID: 22054870
Published date: 2011 Nov 3
Life space and risk of Alzheimer disease, mild cognitive impairment, and cognitive decline in old age.
James BD, Boyle PA, Buchman AS, Barnes LL, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 19 (11):961-9. PubMed PMID: 21430509
Published date: 2011 Nov
Late-life social activity and cognitive decline in old age.
James BD, Wilson RS, Barnes LL, Bennett DA
Journal of the International Neuropsychological Society : JINS 17 (6):998-1005. PubMed PMID: 22040898
Published date: 2011 Nov
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, Dejager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S
Science (New York, N.Y.) 334 (6060):1241-5. PubMed PMID: 22033521
Published date: 2011 Oct 27
Harm avoidance and risk of Alzheimer's disease.
Wilson RS, Boyle PA, Buchman AS, Yu L, Arnold SE, Bennett DA
Psychosomatic medicine 73 (8):690-6. PubMed PMID: 21949425
Published date: 2011 Oct
A life course model of cognitive activities, socioeconomic status, education, reading ability, and cognition.
Jefferson AL, Gibbons LE, Rentz DM, Carvalho JO, Manly J, Bennett DA, Jones RN
Journal of the American Geriatrics Society 59 (8):1403-11. PubMed PMID: 21797830
Published date: 2011 Aug
A genome-wide association study of aging.
Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman
Neurobiology of aging 32 (11):2109.e15-28. PubMed PMID: 21782286
Published date: 2011 Jul 20
Hemoglobin level in older persons and incident Alzheimer disease: prospective cohort analysis.
Shah RC, Buchman AS, Wilson RS, Leurgans SE, Bennett DA
Neurology 77 (3):219-26. PubMed PMID: 21753176
Published date: 2011 Jul 19
Cognitive activities during adulthood are more important than education in building reserve.
Reed BR, Dowling M, Tomaszewski Farias S, Sonnen J, Strauss M, Schneider JA, Bennett DA, Mungas D
Journal of the International Neuropsychological Society : JINS 17 (4):615-24. PubMed PMID: 23131600
Published date: 2011 Jul
Explaining differences in episodic memory performance among older African Americans and Whites: the roles of factors related to cognitive reserve and test bias.
Fyffe DC, Mukherjee S, Barnes LL, Manly JJ, Bennett DA, Crane PK
Journal of the International Neuropsychological Society : JINS 17 (4):625-38. PubMed PMID: 23131601
Published date: 2011 Jul
Datasets for special series on cognitive reserve.
Bennett DA, Barnes LL
Journal of the International Neuropsychological Society : JINS 17 (4):587-92. PubMed PMID: 23131599
Published date: 2011 Jul
Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment.
Trivedi MA, Stoub TR, Murphy CM, George S, deToledo-Morrell L, Shah RC, Whitfield-Gabrieli S, Gabrieli JD, Stebbins GT
Brain imaging and behavior 5 (2):126-36. PubMed PMID: 21328083
Published date: 2011 Jun
Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project.
Negash S, Bennett DA, Wilson RS, Schneider JA, Arnold SE
Current Alzheimer research 8 (4):336-40. PubMed PMID: 21222592
Published date: 2011 Jun
Cognitive function is associated with the development of mobility impairments in community-dwelling elders.
Buchman AS, Boyle PA, Leurgans SE, Barnes LL, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 19 (6):571-80. PubMed PMID: 21606900
Published date: 2011 Jun
Loss of motor function in preclinical Alzheimer's disease.
Buchman AS, Bennett DA
Expert review of neurotherapeutics 11 (5):665-76. PubMed PMID: 21539487
Published date: 2011 May
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kau
Nature genetics 43 (5):436-41. PubMed PMID: 21460841
Published date: 2011 May
Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study.
Buchman AS, Leurgans SE, Boyle PA, Schneider JA, Arnold SA, Bennett DA
BMC medicine 9 (1):42. PubMed PMID: 21507235
Published date: 2011 Apr 20
Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults.
Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L
Neurology 76 (16):1395-402. PubMed PMID: 21490323
Published date: 2011 Apr 19
Vulnerability to stress, anxiety, and development of dementia in old age.
Wilson RS, Begeny CT, Boyle PA, Schneider JA, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 19 (4):327-34. PubMed PMID: 21427641
Published date: 2011 Apr
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, Hardy JA, Huentelman MJ, Corneveaux JJ, Reiman EM, Evans DA, Bennett DA, De Jager PL
Annals of neurology 69 (3):560-9. PubMed PMID: 21391232
Published date: 2011 Mar
Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment.
Wilson RS, Leurgans SE, Boyle PA, Bennett DA
Archives of neurology 68 (3):351-6. PubMed PMID: 21403020
Published date: 2011 Mar
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL
American journal of human genetics 88 (2):232-8. PubMed PMID: 21295279
Published date: 2011 Feb 11
Relation of late-life social activity with incident disability among community-dwelling older adults.
James BD, Boyle PA, Buchman AS, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 66 (4):467-73. PubMed PMID: 21300745
Published date: 2011 Feb 7
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, Mayeux R
PLoS genetics 7 (2):e1001308. PubMed PMID: 21379329
Published date: 2011 Feb
Lewy bodies and olfactory dysfunction in old age.
Wilson RS, Yu L, Schneider JA, Arnold SE, Buchman AS, Bennett DA
Chemical senses 36 (4):367-73. PubMed PMID: 21257733
Published date: 2011 Jan 21
Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study.
Dawe RJ, Bennett DA, Schneider JA, Arfanakis K
PloS one 6 (10):e26286. PubMed PMID: 22043314
Published date: 2011
Odor identification and mortality in old age.
Wilson RS, Yu L, Bennett DA
Chemical senses 36 (1):63-7. PubMed PMID: 20923931
Published date: 2011 Jan
Quantification of the fragmentation of rest-activity patterns in elderly individuals using a state transition analysis.
Lim AS, Yu L, Costa MD, Buchman AS, Bennett DA, Leurgans SE, Saper CB
Sleep 34 (11):1569-81. PubMed PMID: 22043128
Published date: 2011
Heritability of different forms of memory in the Late Onset Alzheimer's Disease Family Study.
Wilson RS, Barral S, Lee JH, Leurgans SE, Foroud TM, Sweet RA, Graff-Radford N, Bird TD, Mayeux R, Bennett DA
Journal of Alzheimer's disease : JAD 23 (2):249-55. PubMed PMID: 20930268
Published date: 2011
Cognitive function is associated with risk aversion in community-based older persons.
Boyle PA, Yu L, Buchman AS, Laibson DI, Bennett DA
BMC geriatrics. PubMed PMID: 21906402
Published date: 2011
Sources of variability in estimates of the prevalence of Alzheimer's disease in the United States.
Wilson RS, Weir DR, Leurgans SE, Evans DA, Hebert LE, Langa KM, Plassman BL, Small BJ, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 7 (1):74-9. PubMed PMID: 21255745
Published date: 2011 Jan
Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults.
Dowling NM, Tomaszewski Farias S, Reed BR, Sonnen JA, Strauss ME, Schneider JA, Bennett DA, Mungas D
Journal of the International Neuropsychological Society : JINS 17 (4):1-13. PubMed PMID: 21092373
Published date: 2010 Nov 22
Association between life space and risk of mortality in advanced age.
Boyle PA, Buchman AS, Barnes LL, James BD, Bennett DA
Journal of the American Geriatrics Society 58 (10):1925-30. PubMed PMID: 20831722
Published date: 2010 Oct
Where vascular meets neurodegenerative disease.
Schneider JA, Bennett DA
Stroke 41 (10 Suppl):S144-6. PubMed PMID: 20876491
Published date: 2010 Oct
Regional brain cortical thinning and systemic inflammation in older persons without dementia.
Fleischman DA, Arfanakis K, Kelly JF, Rajendran N, Buchman AS, Morris MC, Barnes LL, Bennett DA
Journal of the American Geriatrics Society 58 (9):1823-5. PubMed PMID: 20863359
Published date: 2010 Sep
Musculoskeletal pain and incident disability in community-dwelling older adults.
Buchman AS, Shah RC, Leurgans SE, Boyle PA, Wilson RS, Bennett DA
Arthritis care & research 62 (9):1287-93. PubMed PMID: 20853470
Published date: 2010 Sep
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Ma
Archives of neurology 67 (12):1473-1484. PubMed PMID: 20697030
Published date: 2010 Aug 9
Telephone assessment of cognitive function in the late-onset Alzheimer's disease family study.
Wilson RS, Leurgans SE, Foroud TM, Sweet RA, Graff-Radford N, Mayeux R, Bennett DA
Archives of neurology 67 (7):855-61. PubMed PMID: 20625093
Published date: 2010 Jul
Purpose in life is associated with a reduced risk of incident disability among community-dwelling older persons.
Boyle PA, Buchman AS, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 18 (12):1093-102. PubMed PMID: 20808115
Published date: 2010 Jun 10
Kidney function is associated with the rate of cognitive decline in the elderly.
Menkes DL, Buchman AS, Shah RJ, Boyle PA, Bennett DA
Neurology 74 (20):1656; author reply 1. PubMed PMID: 20479368
Published date: 2010 May 18
Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J
Neurobiology of aging 32 (12):2113-22. PubMed PMID: 20452100
Published date: 2010 May 6
Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease.
Wang C, Stebbins GT, Medina DA, Shah RC, Bammer R, Moseley ME, Detoledo-Morrell L
Neurobiology of aging 33 (1):43-52. PubMed PMID: 20359781
Published date: 2010 Mar 30
Effect of a purpose in life on risk of incident Alzheimer disease and mild cognitive impairment in community-dwelling older persons.
Boyle PA, Buchman AS, Barnes LL, Bennett DA
Archives of general psychiatry 67 (3):304-10. PubMed PMID: 20194831
Published date: 2010 Mar
Physical frailty is associated with incident mild cognitive impairment in community-based older persons.
Boyle PA, Buchman AS, Wilson RS, Leurgans SE, Bennett DA
Journal of the American Geriatrics Society 58 (2):248-55. PubMed PMID: 20070417
Published date: 2010 Feb
Parkinsonian signs and incident falls in older persons without Parkinson's disease.
Buracchio T, Arvanitakis Z, Leurgans S, Bennett DA
Journal of the American Geriatrics Society 58 (1):205-6. PubMed PMID: 20122072
Published date: 2010 Jan
Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
Shulman JM, Chibnik LB, Aubin C, Schneider JA, Bennett DA, De Jager PL
PloS one 5 (6):e11244. PubMed PMID: 20574532
Published date: 2010
Loneliness and the rate of motor decline in old age: the Rush Memory and Aging Project, a community-based cohort study.
Buchman AS, Boyle PA, Wilson RS, James BD, Leurgans SE, Arnold SE, Bennett DA
BMC geriatrics. PubMed PMID: 20969786
Published date: 2010
Diabetes and cognitive systems in older black and white persons.
Arvanitakis Z, Bennett DA, Wilson RS, Barnes LL
Alzheimer disease and associated disorders 24 (1):37-42. PubMed PMID: 19568148
Published date: 2010 Jan-Mar
MRI-based volumetric measurement of the substantia innominata in amnestic MCI and mild AD.
George S, Mufson EJ, Leurgans S, Shah RC, Ferrari C, Detoledo-Morrell L
Neurobiology of aging 32 (10):1756-64. PubMed PMID: 20005600
Published date: 2009 Dec 10
Pulmonary function, muscle strength, and incident mobility disability in elders.
Buchman AS, Boyle PA, Leurgans SE, Evans DA, Bennett DA
Proceedings of the American Thoracic Society 6 (7):581-7. PubMed PMID: 19934353
Published date: 2009 Dec 1
The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons.
Boyle PA, Buchman AS, Wilson RS, Kelly JF, Bennett DA
Neuroepidemiology 34 (1):43-9. PubMed PMID: 19907191
Published date: 2010
Association of muscle strength with the risk of Alzheimer disease and the rate of cognitive decline in community-dwelling older persons.
Boyle PA, Buchman AS, Wilson RS, Leurgans SE, Bennett DA
Archives of neurology 66 (11):1339-44. PubMed PMID: 19901164
Published date: 2009 Nov
Kidney function is associated with the rate of cognitive decline in the elderly.
Buchman AS, Tanne D, Boyle PA, Shah RC, Leurgans SE, Bennett DA
Neurology 73 (12):920-7. PubMed PMID: 19657107
Published date: 2009 Sep 22
The neuropathology of probable Alzheimer disease and mild cognitive impairment.
Schneider JA, Arvanitakis Z, Leurgans SE, Bennett DA
Annals of neurology 66 (2):200-8. PubMed PMID: 19743450
Published date: 2009 Aug
Olfactory impairment in presymptomatic Alzheimer's disease.
Wilson RS, Arnold SE, Schneider JA, Boyle PA, Buchman AS, Bennett DA
Annals of the New York Academy of Sciences. PubMed PMID: 19686220
Published date: 2009 Jul
Association between late-life social activity and motor decline in older adults.
Buchman AS, Boyle PA, Wilson RS, Fleischman DA, Leurgans S, Bennett DA
Archives of internal medicine 169 (12):1139-46. PubMed PMID: 19546415
Published date: 2009 Jun 22
Purpose in life is associated with mortality among community-dwelling older persons.
Boyle PA, Barnes LL, Buchman AS, Bennett DA
Psychosomatic medicine 71 (5):574-9. PubMed PMID: 19414613
Published date: 2009 Jun
Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles.
Bennett DA, De Jager PL, Leurgans SE, Schneider JA
Neurology 72 (17):1495-503. PubMed PMID: 19398704
Published date: 2009 Apr 28
Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation.
Dawe RJ, Bennett DA, Schneider JA, Vasireddi SK, Arfanakis K
Magnetic resonance in medicine 61 (4):810-8. PubMed PMID: 19189294
Published date: 2009 Apr
Age-associated reduction of asymmetry in prefrontal function and preservation of conceptual repetition priming.
Bergerbest D, Gabrieli JD, Whitfield-Gabrieli S, Kim H, Stebbins GT, Bennett DA, Fleischman DA
NeuroImage 45 (1):237-46. PubMed PMID: 19015038
Published date: 2009 Mar 1
Relation of hemoglobin to level of cognitive function in older persons.
Shah RC, Wilson RS, Tang Y, Dong X, Murray A, Bennett DA
Neuroepidemiology 32 (1):40-6. PubMed PMID: 19001795
Published date: 2009
Change in frailty and risk of death in older persons.
Buchman AS, Wilson RS, Bienias JL, Bennett DA
Experimental aging research 35 (1):61-82. PubMed PMID: 19173102
Published date: 2009 Jan-Mar
Social engagement and cognitive function in old age.
Krueger KR, Wilson RS, Kamenetsky JM, Barnes LL, Bienias JL, Bennett DA
Experimental aging research 35 (1):45-60. PubMed PMID: 19173101
Published date: 2009 Jan-Mar
Apolipoprotein E e4 allele is associated with more rapid motor decline in older persons.
Buchman AS, Boyle PA, Wilson RS, Beck TL, Kelly JF, Bennett DA
Alzheimer disease and associated disorders 23 (1):63-9. PubMed PMID: 19266700
Published date: 2009 Jan-Mar
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R
Neuron 60 (6):988-1009. PubMed PMID: 19109907
Published date: 2008 Dec 26
Pulmonary function, muscle strength and mortality in old age.
Buchman AS, Boyle PA, Wilson RS, Gu L, Bienias JL, Bennett DA
Mechanisms of ageing and development 129 (11):625-31. PubMed PMID: 18755207
Published date: 2008 Nov
Physical frailty in older persons is associated with Alzheimer disease pathology.
Buchman AS, Schneider JA, Leurgans S, Bennett DA
Neurology 71 (7):499-504. PubMed PMID: 18695161
Published date: 2008 Aug 12
Total daily activity is associated with cognition in older persons.
Buchman AS, Wilson RS, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 16 (8):697-701. PubMed PMID: 18669949
Published date: 2008 Aug
Odor identification and progression of parkinsonian signs in older persons.
Wilson RS, Arnold SE, Buchman AS, Tang Y, Bennett DA
Experimental aging research 34 (3):173-87. PubMed PMID: 18568978
Published date: 2008 Jul-Sep
Processing resources reduce the effect of Alzheimer pathology on other cognitive systems.
Boyle PA, Wilson RS, Schneider JA, Bienias JL, Bennett DA
Neurology 70 (17):1534-42. PubMed PMID: 18354077
Published date: 2008 Apr 22
fMRI activation changes during successful episodic memory encoding and recognition in amnestic mild cognitive impairment relative to cognitively healthy older adults.
Trivedi MA, Murphy CM, Goetz C, Shah RC, Gabrieli JD, Whitfield-Gabrieli S, Turner DA, Stebbins GT
Dementia and geriatric cognitive disorders 26 (2):123-37. PubMed PMID: 18663302
Published date: 2008
Respiratory muscle strength predicts decline in mobility in older persons.
Buchman AS, Boyle PA, Wilson RS, Leurgans S, Shah RC, Bennett DA
Neuroepidemiology 31 (3):174-80. PubMed PMID: 18784416
Published date: 2008
Mixed brain pathologies account for most dementia cases in community-dwelling older persons.
Schneider JA, Arvanitakis Z, Bang W, Bennett DA
Neurology 69 (24):2197-204. PubMed PMID: 17568013
Published date: 2007 Dec 11
Relation of cognitive activity to risk of developing Alzheimer disease.
Wilson RS, Scherr PA, Schneider JA, Tang Y, Bennett DA
Neurology 69 (20):1911-20. PubMed PMID: 17596582
Published date: 2007 Nov 13
Physical activity and leg strength predict decline in mobility performance in older persons.
Buchman AS, Wilson RS, Boyle PA, Tang Y, Fleischman DA, Bennett DA
Journal of the American Geriatrics Society 55 (10):1618-23. PubMed PMID: 17697103
Published date: 2007 Oct
Repetition priming in aging and Alzheimer's disease: an integrative review and future directions.
Fleischman DA
Cortex; a journal devoted to the study of the nervous system and behavior 43 (7):889-97. PubMed PMID: 17941347
Published date: 2007 Oct
Estimation of the mediation effect with a binary mediator.
Li Y, Schneider JA, Bennett DA
Statistics in medicine 26 (18):3398-414. PubMed PMID: 17066450
Published date: 2007 Aug 15
Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons.
Schneider JA, Boyle PA, Arvanitakis Z, Bienias JL, Bennett DA
Annals of neurology 62 (1):59-66. PubMed PMID: 17503514
Published date: 2007 Jul
Olfactory identification and incidence of mild cognitive impairment in older age.
Wilson RS, Schneider JA, Arnold SE, Tang Y, Boyle PA, Bennett DA
Archives of general psychiatry 64 (7):802-8. PubMed PMID: 17606814
Published date: 2007 Jul
Lower extremity motor function and disability in mild cognitive impairment.
Boyle PA, Wilson RS, Buchman AS, Aggarwal NT, Tang Y, Arvanitakis Z, Kelly J, Bennett DA
Experimental aging research 33 (3):355-71. PubMed PMID: 17497375
Published date: 2007 Jul-Sep
Chronic distress and incidence of mild cognitive impairment.
Wilson RS, Schneider JA, Boyle PA, Arnold SE, Tang Y, Bennett DA
Neurology 68 (24):2085-92. PubMed PMID: 17562829
Published date: 2007 Jun 12
Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly.
Buchman AS, Boyle PA, Wilson RS, Tang Y, Bennett DA
Psychosomatic medicine 69 (5):483-9. PubMed PMID: 17556640
Published date: 2007 Jun
Diabetes and parkinsonian signs in older persons.
Arvanitakis Z, Wilson RS, Bienias JL, Bennett DA
Alzheimer disease and associated disorders 21 (2):144-9. PubMed PMID: 17545740
Published date: 2007 Apr-Jun
Physical activity and motor decline in older persons.
Buchman AS, Boyle PA, Wilson RS, Bienias JL, Bennett DA
Muscle & nerve 35 (3):354-62. PubMed PMID: 17143881
Published date: 2007 Mar
Confounding in the Estimation of Mediation Effects.
Li Y, Bienias JL, Bennett DA
Computational statistics & data analysis 51 (6):3173-3186. PubMed PMID: 17940582
Published date: 2007 Mar 1
Loneliness and risk of Alzheimer disease.
Wilson RS, Krueger KR, Arnold SE, Schneider JA, Kelly JF, Barnes LL, Tang Y, Bennett DA
Archives of general psychiatry 64 (2):234-40. PubMed PMID: 17283291
Published date: 2007 Feb
Physical activity is associated with incident disability in community-based older persons.
Boyle PA, Buchman AS, Wilson RS, Bienias JL, Bennett DA
Journal of the American Geriatrics Society 55 (2):195-201. PubMed PMID: 17302655
Published date: 2007 Feb
Terminal cognitive decline: accelerated loss of cognition in the last years of life.
Wilson RS, Beck TL, Bienias JL, Bennett DA
Psychosomatic medicine 69 (2):131-7. PubMed PMID: 17327212
Published date: 2007 Feb-Mar
Change in motor function and risk of mortality in older persons.
Buchman AS, Wilson RS, Boyle PA, Bienias JL, Bennett DA
Journal of the American Geriatrics Society 55 (1):11-9. PubMed PMID: 17233680
Published date: 2007 Jan
Parkinsonian signs and functional disability in old age.
Fleischman DA, Wilson RS, Schneider JA, Bienias JL, Bennett DA
Experimental aging research 33 (1):59-76. PubMed PMID: 17132564
Published date: 2007 Jan-Mar
Correlates of life space in a volunteer cohort of older adults.
Barnes LL, Wilson RS, Bienias JL, de Leon CF, Kim HJ, Buchman AS, Bennett DA
Experimental aging research 33 (1):77-93. PubMed PMID: 17132565
Published date: 2007 Jan-Mar
Memory complaints are related to Alzheimer disease pathology in older persons.
Barnes LL, Schneider JA, Boyle PA, Bienias JL, Bennett DA
Neurology 67 (9):1581-5. PubMed PMID: 17101887
Published date: 2006 Nov 14
The relation of lifetime cognitive activity and lifetime access to resources to late-life cognitive function in older African Americans.
Barnes LL, Wilson RS, de Leon CF, Bennett DA
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition 13 (3-4):516-28. PubMed PMID: 16887787
Published date: 2006 Sep-Dec
Mild cognitive impairment: risk of Alzheimer disease and rate of cognitive decline.
Boyle PA, Wilson RS, Aggarwal NT, Tang Y, Bennett DA
Neurology 67 (3):441-5. PubMed PMID: 16894105
Published date: 2006 Aug 8
Harm avoidance and disability in old age.
Wilson RS, Buchman AS, Arnold SE, Shah RC, Tang Y, Bennett DA
Experimental aging research 32 (3):243-61. PubMed PMID: 16754467
Published date: 2006 Jul-Sep
Postmortem indices linking risk factors to cognition: results from the Religious Order Study and the Memory and Aging Project.
Bennett DA
Alzheimer disease and associated disorders 20 (3 Suppl 2):S63-8. PubMed PMID: 16917198
Published date: 2006 Jul-Sep
Neuropathology of older persons without cognitive impairment from two community-based studies.
Bennett DA, Schneider JA, Arvanitakis Z, Kelly JF, Aggarwal NT, Shah RC, Wilson RS
Neurology 66 (12):1837-44. PubMed PMID: 16801647
Published date: 2006 Jun 27
Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer's disease.
Stoub TR, deToledo-Morrell L, Stebbins GT, Leurgans S, Bennett DA, Shah RC
Proceedings of the National Academy of Sciences of the United States of America 103 (26):10041-5. PubMed PMID: 16785436
Published date: 2006 Jun 27
The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study.
Bennett DA, Schneider JA, Tang Y, Arnold SE, Wilson RS
The Lancet. Neurology 5 (5):406-12. PubMed PMID: 16632311
Published date: 2006 May
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, Bennett DA, Leurgans S, Turner DA, Stebbins GT
Neurobiology of aging 27 (5):663-72. PubMed PMID: 16005548
Published date: 2006 May
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, Bennett DA, Leurgans S, Turner DA, Stebbins GT
Neurobiology of aging 27 (5):663-72. PubMed PMID: 16005548
Published date: 2006 May
Childhood adversity and psychosocial adjustment in old age.
Wilson RS, Krueger KR, Arnold SE, Barnes LL, Mendes de Leon CF, Bienias JL, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 14 (4):307-15. PubMed PMID: 16582039
Published date: 2006 Apr
Diabetes and function in different cognitive systems in older individuals without dementia.
Arvanitakis Z, Wilson RS, Li Y, Aggarwal NT, Bennett DA
Diabetes care 29 (3):560-5. PubMed PMID: 16505506
Published date: 2006 Mar
Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study.
Bennett DA, Schneider JA, Aggarwal NT, Arvanitakis Z, Shah RC, Kelly JF, Fox JH, Cochran EJ, Arends D, Treinkman AD, Wilson RS
Neuroepidemiology 27 (3):169-76. PubMed PMID: 17035694
Published date: 2006
Odor identification and decline in different cognitive domains in old age.
Wilson RS, Arnold SE, Tang Y, Bennett DA
Neuroepidemiology 26 (2):61-7. PubMed PMID: 16352908
Published date: 2006
Chronic psychological distress and risk of Alzheimer's disease in old age.
Wilson RS, Arnold SE, Schneider JA, Kelly JF, Tang Y, Bennett DA
Neuroepidemiology 27 (3):143-53. PubMed PMID: 16974109
Published date: 2006
Parkinsonian signs in subjects with mild cognitive impairment.
Boyle PA, Wilson RS, Aggarwal NT, Arvanitakis Z, Kelly J, Bienias JL, Bennett DA
Neurology 65 (12):1901-6. PubMed PMID: 16380610
Published date: 2005 Dec 27
Parkinsonian signs and cognitive function in old age.
Fleischman DA, Wilson RS, Bienias JL, Bennett DA
Journal of the International Neuropsychological Society : JINS 11 (5):591-7. PubMed PMID: 16212686
Published date: 2005 Sep
Early and late life cognitive activity and cognitive systems in old age.
Wilson RS, Barnes LL, Krueger KR, Hoganson G, Bienias JL, Bennett DA
Journal of the International Neuropsychological Society : JINS 11 (4):400-7. PubMed PMID: 16209420
Published date: 2005 Jul
MRI predictors of risk of incident Alzheimer disease: a longitudinal study.
Stoub TR, Bulgakova M, Leurgans S, Bennett DA, Fleischman D, Turner DA, deToledo-Morrell L
Neurology 64 (9):1520-4. PubMed PMID: 15883311
Published date: 2005 May 10
Proneness to psychological distress and risk of Alzheimer disease in a biracial community.
Wilson RS, Barnes LL, Bennett DA, Li Y, Bienias JL, Mendes de Leon CF, Evans DA
Neurology 64 (2):380-2. PubMed PMID: 15668449
Published date: 2005 Jan 25
The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort.
Bennett DA, Schneider JA, Buchman AS, Mendes de Leon C, Bienias JL, Wilson RS
Neuroepidemiology 25 (4):163-75. PubMed PMID: 16103727
Published date: 2005
MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD.
deToledo-Morrell L, Stoub TR, Bulgakova M, Wilson RS, Bennett DA, Leurgans S, Wuu J, Turner DA
Neurobiology of aging 25 (9):1197-203. PubMed PMID: 15312965
Published date: 2004 Oct
Assessment of lifetime participation in cognitively stimulating activities.
Wilson R, Barnes L, Bennett D
Journal of clinical and experimental neuropsychology 25 (5):634-42. PubMed PMID: 12815501
Published date: 2003 Aug