Study Publications for ROS

Overview of Cohort — Religious Orders Study (ROS)

Religious Orders Study and Rush Memory and Aging Project
Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA.
J Alzheimers Dis. 64(s1):S161-S189. PubMed PMID: 29865057
Published date: 2018 Jun 12

Overview and findings from the religious orders study.
Bennett DA, Schneider JA, Arvanitakis Z, Wilson RS.
Curr Alzheimer Res. 9(6):628-45. PubMed PMID: 22471860
Published date: 2012 Jul;


Other Publications

Proportion of cognitive loss attributable to terminal decline.
Wilson RS, Yu L, Leurgans SE, Bennett DA, Boyle PA
Neurology. PubMed PMID: 31792096
Published date: 2019 Dec 02
Time course of neuropsychiatric symptoms and cognitive diagnosis in National Alzheimer's Coordinating Centers volunteers.
Wise EA, Rosenberg PB, Lyketsos CG, Leoutsakos JM
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 31024987
Published date: 2019 Dec
Braak neurofibrillary tangle staging prediction from invivo MRI metrics.
Dallaire-Throux C, Beheshti I, Potvin O, Dieumegarde L, Saikali S, Duchesne S
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 31517022
Published date: 2019 Dec
What Is Dementia?
Arvanitakis Z, Bennett DA
JAMA 322 (17):1728. PubMed PMID: 31688886
Published date: 2019 11 05
APOE 4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease.
Moore AM, Mahoney E, Dumitrescu L, De Jager PL, Koran MEI, Petyuk VA, Robinson RA, Ruderfer DM, Cox NJ, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ
Neurobiology of aging. PubMed PMID: 31791659
Published date: 2019 Nov 05
Brain and blood metabolome for Alzheimer's dementia: findings from a targeted metabolomics analysis.
Huo Z, Yu L, Yang J, Zhu Y, Bennett DA, Zhao J
Neurobiology of aging. PubMed PMID: 31785839
Published date: 2019 Nov 05
Cognitive and functional progression of dementia in two longitudinal studies.
Wang Y, Haaksma ML, Ramakers IHGB, Verhey FRJ, van de Flier WM, Scheltens P, van Maurik I, Olde Rikkert MGM, Leoutsakos JS, Melis RJF
International journal of geriatric psychiatry 34 (11):1623-1632. PubMed PMID: 31318090
Published date: 2019 Nov
Associations of autozygosity with a broad range of human phenotypes.
Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK, Lin K, Zhao JH, Deelen P, Rohde R, Schurmann C, Guo X, Giulianini F, Zhang W, Medina-Gomez C, Karlsson R, Bao Y, Bartz TM, Baumbach C, Biino G, Bixley MJ, Brumat M, Chai J
Nature communications 10 (1):4957. PubMed PMID: 31673082
Published date: 2019 Oct 31
Diagnosis and Management of Dementia: Review.
Arvanitakis Z, Shah RC, Bennett DA
JAMA 322 (16):1589-1599. PubMed PMID: 31638686
Published date: 2019 Oct 22
Genetic architecture of subcortical brain structures in 38,851 individuals.
Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desri
Nature genetics 51 (11):1624-1636. PubMed PMID: 31636452
Published date: 2019 Oct 21
Association Between High School Personality Phenotype and Dementia 54 Years Later in Results From a National US Sample.
Chapman BP, Huang A, Peters K, Horner E, Manly J, Bennett DA, Lapham S
JAMA psychiatry. PubMed PMID: 31617877
Published date: 2019 Oct 16
Hospitalization, Alzheimer's and Related Neuropathologies, and Cognitive Decline.
James BD, Wilson RS, Capuano AW, Boyle PA, Shah RC, Lamar M, Ely EW, Bennett DA, Schneider JA
Annals of neurology 86 (6):844-852. PubMed PMID: 31614018
Published date: 2019 Oct 15
Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM
Cell reports 29 (2):301-316.e10. PubMed PMID: 31597093
Published date: 2019 Oct 08
Genetic risk for Alzheimer's dementia predicts motor deficits through multi-omic systems in older adults.
Tasaki S, Gaiteri C, Petyuk VA, Blizinsky KD, De Jager PL, Buchman AS, Bennett DA
Translational psychiatry 9 (1):241. PubMed PMID: 31582723
Published date: 2019 Oct 03
Regulation of lifespan by neural excitation and REST.
Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaicovo MP, Yankner BA
Nature 574 (7778):359-364. PubMed PMID: 31619788
Published date: 2019 Oct
Common age-related neuropathologies and yearly variability in cognition.
Yu L, Wang T, Wilson RS, Leurgans S, Schneider JA, Bennett DA, Boyle PA
Annals of clinical and translational neurology 6 (11):2140-2149. PubMed PMID: 31568713
Published date: 2019 Sep 30
The Health and Retirement Study Harmonized Cognitive Assessment Protocol Project: Study Design and Methods.
Langa KM, Ryan LH, McCammon RJ, Jones RN, Manly JJ, Levine DA, Sonnega A, Farron M, Weir DR
Neuroepidemiology. PubMed PMID: 31563909
Published date: 2019 Sep 27
Accelerometer Physical Activity is Associated with Greater Gray Matter Volumes in Older Adults Without Dementia or Mild Cognitive Impairment.
Halloway S, Arfanakis K, Wilbur J, Schoeny ME, Pressler SJ
The journals of gerontology. Series B, Psychological sciences and social sciences 74 (7):1142-1151. PubMed PMID: 29432610
Published date: 2019 Sep 15
Sex differences in mixed neuropathologies in community-dwelling older adults.
Barnes LL, Lamar M, Schneider JA
Brain research. PubMed PMID: 31128096
Published date: 2019 Sep 15
Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.
Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, Bennett DA, Gearing M, Juncos JL, Kramer J, Lee SE, Yokoyama JS, Mendez MF, Chui
Alzheimer disease and associated disorders 33 (4):327-330. PubMed PMID: 31513029
Published date: 2019 Sep 10
Sex differences in the genetic predictors of Alzheimer's pathology.
Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Bush WS, Gifford KA, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Deming Y, Chao MJ, Huentelman M, Martin ER, Hamilton-Nelson K, S
Brain : a journal of neurology 142 (9):2581-2589. PubMed PMID: 31497858
Published date: 2019 Sep 01
The Multilingual Naming Test (MINT) as a Measure of Picture Naming Ability in Alzheimer's Disease.
Stasenko A, Jacobs DM, Salmon DP, Gollan TH
Journal of the International Neuropsychological Society : JINS 25 (8):821-833. PubMed PMID: 31248465
Published date: 2019 Sep
Factors influencing attrition in 35 Alzheimer's Disease Centers across the USA: a longitudinal examination of the National Alzheimer's Coordinating Center's Uniform Data Set.
Burke SL, Hu T, Naseh M, Fava NM, O'Driscoll J, Alvarez D, Cottler LB, Duara R
Aging clinical and experimental research 31 (9):1283-1297. PubMed PMID: 30535620
Published date: 2019 Sep
Trajectories of neuropsychiatric symptoms over time in healthy volunteers and risk of MCI and dementia.
Leoutsakos JS, Wise EA, Lyketsos CG, Smith GS
International journal of geriatric psychiatry 34 (12):1865-1873. PubMed PMID: 31452260
Published date: 2019 Aug 26
Cognitive function and neuropathological outcomes: a forward-looking approach.
Munoz E, Filshtein T, Bettcher BM, McLaren D, Hedden T, Tommet D, Mungas D, Therneau T
Journal of neurology 266 (12):2920-2928. PubMed PMID: 31435771
Published date: 2019 Aug 21
Using Transcriptomic Hidden Variables to Infer Context-Specific Genotype Effects in the Brain.
Ng B, Casazza W, Patrick E, Tasaki S, Novakovsky G, Felsky D, Ma Y, Bennett DA, Gaiteri C, De Jager PL, Mostafavi S
American journal of human genetics 105 (3):562-572. PubMed PMID: 31447098
Published date: 2019 Aug 21
Insulin and adipokine signaling and their cross-regulation in postmortem human brain.
Wang HY, Capuano AW, Khan A, Pei Z, Lee KC, Bennett DA, Ahima RS, Arnold SE, Arvanitakis Z
Neurobiology of aging. PubMed PMID: 31539648
Published date: 2019 Aug 20
Cognitive heterogeneity in probable Alzheimer disease: Clinical and neuropathologic features.
Qiu Y, Jacobs DM, Messer K, Salmon DP, Feldman HH
Neurology 93 (8):e778-e790. PubMed PMID: 31320469
Published date: 2019 Aug 20
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE 4 on Alzheimer's Disease Risk in a Multiracial Sample.
Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, Chong A, Byun MS, Seo S, Ko PW, Han JW, McLean C, Farrell J, Lunetta KL, Miyashita A, Hara N, Won S, Choi SM, Ha JM, Jeong J
Journal of clinical medicine. PubMed PMID: 31426376
Published date: 2019 Aug 16
cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis.
Ojelade SA, Lee TV, Giagtzoglou N, Yu L, Ugur B, Li Y, Duraine L, Zuo Z, Petyuk V, De Jager PL, Bennett DA, Arenkiel BR, Bellen HJ, Shulman JM
Cell reports 28 (7):1799-1813.e5. PubMed PMID: 31412248
Published date: 2019 Aug 13
Depression, subjective cognitive decline, and the risk of neurocognitive disorders.
Liew TM
Alzheimer's research & therapy 11 (1):70. PubMed PMID: 31399132
Published date: 2019 Aug 09
The Association Between the Number of Neuropsychological Measures and the Base Rate of Low Scores.
Oltra-Cucarella J, Snchez-SanSegundo M, Rubio-Aparicio M, Arango-Lasprilla JC, Ferrer-Cascales R
Assessment. PubMed PMID: 31364385
Published date: 2019 Jul 31
Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Dat
Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML
Alzheimer's research & therapy 11 (1):64. PubMed PMID: 31351489
Published date: 2019 Jul 27
Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline.
Kim N, Yu L, Dawe R, Petyuk VA, Gaiteri C, De Jager PL, Schneider JA, Arfanakis K, Bennett DA
Neurobiology of aging. PubMed PMID: 31479860
Published date: 2019 Jul 26
Group differences in normal neuropsychological test performance for older non-Hispanic White and Black/African American adults.
Werry AE, Daniel M, Bergstrm B
Neuropsychology 33 (8):1089-1100. PubMed PMID: 31343234
Published date: 2019 Jul 25
Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology.
Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Chen Y, Chen K, Chao MV, Counts SE, Mufson EJ
Neurobiology of disease. PubMed PMID: 31349032
Published date: 2019 Jul 23
Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer's Disease.
Canchi S, Raao B, Masliah D, Rosenthal SB, Sasik R, Fisch KM, De Jager PL, Bennett DA, Rissman RA
Cell reports 28 (4):1103-1116.e4. PubMed PMID: 31340147
Published date: 2019 Jul 23
Brain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer's disease.
Mahoney ER, Dumitrescu L, Moore AM, Cambronero FE, De Jager PL, Koran MEI, Petyuk VA, Robinson RAS, Goyal S, Schneider JA, Bennett DA, Jefferson AL, Hohman TJ
Molecular psychiatry. PubMed PMID: 31332262
Published date: 2019 Jul 22
Alzheimer's disease frequency peaks in the tenth decade and is lower afterwards.
Farfel JM, Yu L, Boyle PA, Leurgans S, Shah RC, Schneider JA, Bennett DA
Acta neuropathologica communications 7 (1):104. PubMed PMID: 31269985
Published date: 2019 Jul 03
The impact of cardiovascular risk factors on cognition in Hispanics and non-Hispanic whites.
Stickel A, McKinnon A, Ruiz J, Grilli MD, Ryan L
Learning & memory (Cold Spring Harbor, N.Y.) 26 (7):235-244. PubMed PMID: 31209118
Published date: 2019 Jul
Clinical diagnoses among individuals with primary age-related tauopathy versus Alzheimer's neuropathology.
Teylan M, Besser LM, Crary JF, Mock C, Gauthreaux K, Thomas NM, Chen YC, Kukull WA
Laboratory investigation; a journal of technical methods and pathology 99 (7):1049-1055. PubMed PMID: 30710118
Published date: 2019 Jul
Discriminative Ability of Montreal Cognitive Assessment Subtests and Items in Racial and Ethnic Minority Groups.
Milani SA, Marsiske M, Striley CW
Alzheimer disease and associated disorders 33 (3):226-232. PubMed PMID: 31058685
Published date: 2019 Jul-Sep
Associations Between Depression, Traumatic Brain Injury, and Cognitively-Defined Late-Onset Alzheimer's Disease Subgroups.
Bauman J, Gibbons LE, Moore M, Mukherjee S, McCurry SM, McCormick W, Bowen JD, Trittschuh E, Glymour M, Mez J, Saykin AJ, Dams-O'Conner K, Bennett DA, Larson EB, Crane PK
Journal of Alzheimer's disease : JAD 70 (2):609-617. PubMed PMID: 31256124
Published date: 2019 Jun 24
TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits.
Nagpal S, Meng X, Epstein MP, Tsoi LC, Patrick M, Gibson G, De Jager PL, Bennett DA, Wingo AP, Wingo TS, Yang J
American journal of human genetics 105 (2):258-266. PubMed PMID: 31230719
Published date: 2019 Jun 10
HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease.
Mahady L, Nadeem M, Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ
Neuropathology and applied neurobiology 45 (4):380-397. PubMed PMID: 30252960
Published date: 2019 Jun
Novel methods for integration and visualization of genomics and genetics data in Alzheimer's disease.
Bihlmeyer NA, Merrill E, Lambert Y, Srivastava GP, Clark TW, Hyman BT, Das S
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (6):788-798. PubMed PMID: 30935898
Published date: 2019 Jun
Rate of brain aging and APOE 4 are synergistic risk factors for Alzheimer's disease.
Glorioso CA, Pfenning AR, Lee SS, Bennett DA, Sibille EL, Kellis M, Guarente LP
Life science alliance 2 (3):2218-9. PubMed PMID: 31133613
Published date: 2019 Jun
Polypharmacy in an Elderly Population: Enhancing Medication Management Through the Use of Clinical Decision Support Software Platforms.
Keine D, Zelek M, Walker JQ, Sabbagh MN
Neurology and therapy 8 (1):79-94. PubMed PMID: 30900186
Published date: 2019 Jun
Motoric cognitive risk syndrome and predictors of transition to dementia: A multicenter study.
Verghese J, Wang C, Bennett DA, Lipton RB, Katz MJ, Ayers E
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (7):870-877. PubMed PMID: 31164315
Published date: 2019 Jun 01
CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, Lunetta KL
Aging cell 18 (4):e12964. PubMed PMID: 31144443
Published date: 2019 May 29
Epigenetic dysregulation of enhancers in neurons is associated with Alzheimer's disease pathology and cognitive symptoms.
Li P, Marshall L, Oh G, Jakubowski JL, Groot D, He Y, Wang T, Petronis A, Labrie V
Nature communications 10 (1):2246. PubMed PMID: 31113950
Published date: 2019 05 21
Genome-wide association studies of alcohol dependence, DSM-IV criterion count, and individual criteria.
Lai D, Wetherill L, Bertelsen S, Carey CE, Kamarajan C, Kapoor M, Meyers JL, Anokhin AP, Bennett DA, Bucholz KK, Chang KK, De Jager PL, Dick DM, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Raj T, Schuckit M, Scott DM, Taylor RE, Tischfield J, Hari
Genes, brain, and behavior 18 (6):e12579. PubMed PMID: 31090166
Published date: 2019 May 14
Antiphospholipid Antibodies: Cognitive and Motor Decline, Neuroimaging and Neuropathology.
Arvanitakis Z, Capuano AW, Brey R, Fleischman DA, Arfanakis K, Buchman AS, Schneider JA, Levine SR, Bennett DA
Neuroepidemiology 53 (1-2):1-8. PubMed PMID: 31067547
Published date: 2019 May 08
Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease.
Tosto G, Vardarajan B, Sariya S, Brickman AM, Andrews H, Manly JJ, Schupf N, Reyes-Dumeyer D, Lantigua R, Bennett DA, De Jager PL, Mayeux R
JAMA neurology. PubMed PMID: 31058951
Published date: 2019 May 06
Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia.
Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (5):686-698. PubMed PMID: 30852157
Published date: 2019 May
Single-cell transcriptomic analysis of Alzheimer's disease.
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH
Nature 570 (7761):332-337. PubMed PMID: 31042697
Published date: 2019 May 01
Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease.
Vglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, Karch CM, Cairns N, Mori H, Schofield PR, Masters CL, Goate A, Buckles V, Fox N,
Brain : a journal of neurology 142 (5):1429-1440. PubMed PMID: 30897203
Published date: 2019 May 01
Association of Cortical β-Amyloid Protein in the Absence of Insoluble Deposits With Alzheimer Disease.
Yu L, Petyuk VA, Tasaki S, Boyle PA, Gaiteri C, Schneider JA, De Jager PL, Bennett DA
JAMA neurology 34 (4):493-511. PubMed PMID: 31009033
Published date: 2019 Apr 22
Cholinesterase Inhibitors May Not Benefit Mild Cognitive Impairment and Mild Alzheimer Disease Dementia.
Han JY, Besser LM, Xiong C, Kukull WA, Morris JC
Alzheimer disease and associated disorders 33 (2):87-94. PubMed PMID: 30633043
Published date: 2019 Apr-Jun
Confidence Intervals for the Area Under the Receiver Operating Characteristic Curve in the Presence of Ignorable Missing Data.
Cho H, Matthews GJ, Harel O
International statistical review = Revue internationale de statistique 87 (1):152-177. PubMed PMID: 31007356
Published date: 2019 Apr
Progressive parkinsonism in older adults is related to the burden of mixed brain pathologies.
Buchman AS, Yu L, Wilson RS, Leurgans SE, Nag S, Shulman JL, Barnes LL, Schneider JA, Bennett DA
Neurology 92 (16):e1821-e1830. PubMed PMID: 30894446
Published date: 2019 Mar 20
White matter correlates of scam susceptibility in community-dwelling older adults.
Lamar M, Arfanakis K, Yu L, Zhang S, Han SD, Fleischman DA, Bennett DA, Boyle PA
Brain imaging and behavior. PubMed PMID: 30895444
Published date: 2019 Mar 20
Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons.
Capuano AW, Wilson RS, Honer WG, Petyuk VA, Leurgans SE, Yu L, Gatchel JR, Arnold S, Bennett DA, Arvanitakis Z
Journal of affective disorders. PubMed PMID: 30875674
Published date: 2019 Mar 08
Integrative approach to sporadic Alzheimer's disease:deficiency of TYROBPin cerebral A amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing A
Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME
Molecular psychiatry 24 (3):431-446. PubMed PMID: 30283032
Published date: 2019 03
Prioritizing Parkinson's disease genes using population-scale transcriptomic data.
Li YI, Wong G, Humphrey J, Raj T
Nature communications 10 (1):994. PubMed PMID: 30824768
Published date: 2019 03 01
Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A, tau, immunity and lipid processing.
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, R
Nature genetics 51 (3):414-430. PubMed PMID: 30820047
Published date: 2019 03
A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease.
Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (3):441-452. PubMed PMID: 30503768
Published date: 2019 Mar
Sedentary Time and White Matter Hyperintensity Volume in Older Adults.
Bronas UG, Steffen A, Dion C, Boots EA, Arfanakis K, Marquez DX, Lamar M
Medicine and science in sports and exercise 51 (8):1613-1618. PubMed PMID: 30817720
Published date: 2019 Feb 20
Beta-amyloid pathology in human brain microvessel extracts from the parietal cortex: relation with cerebral amyloid angiopathy and Alzheimer's disease.
Bourassa P, Tremblay C, Schneider JA, Bennett DA, Calon F
Acta neuropathologica 137 (5):801-823. PubMed PMID: 30729296
Published date: 2019 Feb 07
Education and cognitive reserve in old age.
Wilson RS, Yu L, Lamar M, Schneider JA, Boyle PA, Bennett DA
Neurology 92 (10):e1041-e1050. PubMed PMID: 30728309
Published date: 2019 Feb 06
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
Karlsson Linnr R, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Tino SP, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Trzaskowski M, Vlaming R, Znd CL, Bao Y, Buzdugan L, Caplin AH, Chen CY, Eibich P, Fonta
Nature genetics 51 (2):245-257. PubMed PMID: 30643258
Published date: 2019 02
Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults.
Makkinejad N, Schneider JA, Yu J, Leurgans SE, Kotrotsou A, Evia AM, Bennett DA, Arfanakis K
Neurobiology of aging 77 (11):104-111. PubMed PMID: 30784812
Published date: 2019 Jan 31
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Tan CH, Bonham LW, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Yokoyama JS, Rabinovici GD, Miller BL, Yaffe K, Schellenberg GD, Kauppi K, Holland D, McEvoy LK, Kukull WA, Tosun D, Weiner MW, Sperling RA, Bennett DA, Hyman BT, Andreassen OA, Dale AM,
Brain : a journal of neurology 142 (2):460-470. PubMed PMID: 30689776
Published date: 2019 Jan 24
Neuropathological correlates and genetic architecture of microglial activation in elderly human brain.
Felsky D, Roostaei T, Nho K, Risacher SL, Bradshaw EM, Petyuk V, Schneider JA, Saykin A, Bennett DA, De Jager PL
Nature communications 10 (1):409. PubMed PMID: 30679421
Published date: 2019 Jan 24
Postmortem neurodegenerative markers and trajectories of decline in cognitive systems.
Wilson RS, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Bennett DA, Boyle PA
Neurology 92 (8):e831-e840. PubMed PMID: 30674595
Published date: 2019 Jan 23
Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain.
Dintica CS, Marseglia A, Rizzuto D, Wang R, Seubert J, Arfanakis K, Bennett DA, Xu W
Neurology 92 (7):e700-e709. PubMed PMID: 30651382
Published date: 2019 Jan 16
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.
Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartans
Neurology. PubMed PMID: 30651383
Published date: 2019 Jan 16
Causes and Patterns of Dementia: An Update in the Era of Redefining Alzheimer's Disease.
James BD, Bennett DA
Annual review of public health. PubMed PMID: 30642228
Published date: 2019 Jan 14
Cognitive decline after elective and nonelective hospitalizations in older adults.
James BD, Wilson RS, Capuano AW, Boyle PA, Shah RC, Lamar M, Ely EW, Bennett DA, Schneider JA
Neurology 92 (7):e690-e699. PubMed PMID: 30635482
Published date: 2019 Jan 11
Biomarkers for Alzheimer Dementia in Diverse Racial and Ethnic Minorities-A Public Health Priority.
Barnes LL
JAMA neurology 76 (3):251-253. PubMed PMID: 30615027
Published date: 2019 Jan 07
Abnormal Sleep Behaviours Across the Spectrum of Alzheimer's Disease Severity: Influence of APOE Genotypes and Lewy Bodies.
Koo KYG, Schweizer TA, Fischer CE, Munoz DG
Current Alzheimer research 16 (3):243-250. PubMed PMID: 30605058
Published date: 2019
Genetic Sample Provision Among National Alzheimer's Coordinating Center Participants.
Bardach SH, Jicha GA, Karanth S, Zhang X, Abner EL
Journal of Alzheimer's disease : JAD 69 (1):123-133. PubMed PMID: 30958359
Published date: 2019
Cerebral Amyloid Angiopathy and Neuritic Plaque Pathology Correlate with Cognitive Decline in Elderly Non-Demented Individuals.
Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ
Journal of Alzheimer's disease : JAD 67 (1):411-422. PubMed PMID: 30594928
Published date: 2019
Exploring the Correlation between the Cognitive Benefits of Drug Combinations in a Clinical Database and the Efficacies of the Same Drug Combinations Predicted from a Computational Model.
Anastasio TJ
Journal of Alzheimer's disease : JAD 70 (1):287-302. PubMed PMID: 31177222
Published date: 2019
Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease.
Mufson EJ, Counts SE, Ginsberg SD, Mahady L, Perez SE, Massa SM, Longo FM, Ikonomovic MD
Frontiers in neuroscience. PubMed PMID: 31312116
Published date: 2019
A genome-wide association study identifies genetic loci associated with specific lobar brain volumes.
van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupki
Communications biology. PubMed PMID: 31396565
Published date: 2019
3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice.
Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH
Communications biology. PubMed PMID: 31602409
Published date: 2019
The Pathology of Rapid Cognitive Decline in Clinically Diagnosed Alzheimer's Disease.
Nance C, Ritter A, Miller JB, Lapin B, Banks SJ
Journal of Alzheimer's disease : JAD 70 (4):983-993. PubMed PMID: 31306127
Published date: 2019
Reliability of Medical History Reporting in Older Adults With and Without Cognitive Impairment.
Curcio N, Wilmoth K, LoBue C, Cullum CM
Journal of central nervous system disease. PubMed PMID: 31040738
Published date: 2019
Expanding instrumented gait testing in the community setting: A portable, depth-sensing camera captures joint motion in older adults.
Dawe RJ, Yu L, Leurgans SE, Truty T, Curran T, Hausdorff JM, Wimmer MA, Block JA, Bennett DA, Buchman AS
PloS one 14 (5):e0215995. PubMed PMID: 31091267
Published date: 2019
Parental Perception of the Factors that Affect Diabetes Management in Youth.
Davis V, Telang SB, Jain S, Davis Ramos MV, Ward MA, Jindal I, Aschkenasy JR, Glover CM, Shah RC
Clinical diabetes : a publication of the American Diabetes Association 37 (1):50-56. PubMed PMID: 30705497
Published date: 2019 Jan
Cognition may link cortical IGFBP5 levels with motor function in older adults.
Buchman AS, Yu L, Petyuk VA, Gaiteri C, Tasaki S, Blizinsky KD, Schneider JA, De Jager PL, Bennett DA
PloS one 14 (8):e0220968. PubMed PMID: 31404102
Published date: 2019
Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study.
Oh G, Abner EL, Fardo DW, Freeman PR, Moga DC
PloS one 14 (1):e0210341. PubMed PMID: 30633773
Published date: 2019
Disease severity and minimal clinically important differences in clinical outcome assessments for Alzheimer's disease clinical trials.
Andrews JS, Desai U, Kirson NY, Zichlin ML, Ball DE, Matthews BR
Alzheimer's & dementia (New York, N. Y.). PubMed PMID: 31417957
Published date: 2019
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL
Nature neuroscience 22 (1):37-46. PubMed PMID: 30559478
Published date: 2019 Jan
Associations between Comorbid TDP-43, Lewy Body Pathology, and Neuropsychiatric Symptoms in Alzheimer's Disease.
Bayram E, Shan G, Cummings JL
Journal of Alzheimer's disease : JAD 69 (4):953-961. PubMed PMID: 31127776
Published date: 2019
DNA methylation variability in Alzheimer's disease.
Huo Z, Zhu Y, Yu L, Yang J, De Jager P, Bennett DA, Zhao J
Neurobiology of aging. PubMed PMID: 30660039
Published date: 2018 Dec 21
Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model.
Wang H, Li Y, Ryder JW, Hole JT, Ebert PJ, Airey DC, Qian HR, Logsdon B, Fisher A, Ahmed Z, Murray TK, Cavallini A, Bose S, Eastwood BJ, Collier DA, Dage JL, Miller BB, Merchant KM, O'Neill MJ, Demattos RB
Molecular neurodegeneration 13 (1):65. PubMed PMID: 30558641
Published date: 2018 12 17
Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.
Mukherjee S, Mez J, Trittschuh EH, Saykin AJ, Gibbons LE, Fardo DW, Wessels M, Bauman J, Moore M, Choi SE, Gross AL, Rich J, Louden DKN, Sanders RE, Grabowski TJ, Bird TD, McCurry SM, Snitz BE, Kamboh MI, Lopez OL, De Jager PL, Bennett DA, Keene CD, Larso
Molecular psychiatry. PubMed PMID: 30514930
Published date: 2018 Dec 04
Performance validity in older adults: Observed versus predicted false positive rates in relation to number of tests administered.
Davis JJ
Journal of clinical and experimental neuropsychology 40 (10):1013-1021. PubMed PMID: 29779432
Published date: 2018 12
Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations.
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V, Starks T, Byfield GE, Sierra Lopez CB, McCauley JL, Acosta H, Chinea A, Kunkle BW, Reitz C, Farrer LA, Schellenberg GD, Vardar
PLoS genetics 14 (12):e1007791. PubMed PMID: 30517106
Published date: 2018 12
Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease.
Beecham GW, Vardarajan B, Blue E, Bush W, Jaworski J, Barral S, DeStefano A, Hamilton-Nelson K, Kunkle B, Martin ER, Naj A, Rajabli F, Reitz C, Thornton T, van Duijn C, Goate A, Seshadri S, Farrer LA, Boerwinkle E, Schellenberg G, Haines JL, Wijsman E, Ma
Neurology. Genetics 4 (6):e286. PubMed PMID: 30569016
Published date: 2018 Dec
Bias in parameter estimates due to omitting gene-environment interaction terms in case-control studies.
Lobach I
Genetic epidemiology 42 (8):838-845. PubMed PMID: 30302820
Published date: 2018 12
Toward Prevention of Mild Cognitive Impairment in Older Adults With Depression: An Observational Study of Potentially Modifiable Risk Factors.
Gallagher D, Kiss A, Lanctot KL, Herrmann N
The Journal of clinical psychiatry. PubMed PMID: 30549490
Published date: 2018 11 27
Quantitative Assessment of Pathological Tau Burden in Essential Tremor: A Postmortem Study.
Farrell K, Cosentino S, Iida MA, Chapman S, Bennett DA, Faust PL, Louis ED, Crary JF
Journal of neuropathology and experimental neurology 78 (1):31-37. PubMed PMID: 30476290
Published date: 2018 Nov 23
Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies.
Boyle PA, Yu L, Leurgans SE, Wilson RS, Brookmeyer R, Schneider JA, Bennett DA
Annals of neurology 85 (1):114-124. PubMed PMID: 30421454
Published date: 2018 Nov 12
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, Mormino EC, Sperling RA, Bennett DA, McEvoy LK, Brewer JB, Feldman HH, Hyman BT, Pericak-Vanc
Acta neuropathologica 137 (2):209-226. PubMed PMID: 30413934
Published date: 2018 Nov 09
Candidate-based screening via gene modulation in human neurons and astrocytes implicates FERMT2 in Aβ and TAU proteostasis.
Sullivan SE, Liao M, Smith RV, White C, Lagomarsino VN, Xu J, Taga M, Bennett DA, De Jager PL, Young-Pearse TL
Human molecular genetics 28 (5):718-735. PubMed PMID: 30371777
Published date: 2018 Oct 26
In vivo hippocampal subfield shape related to TDP-43, amyloid beta, and tau pathologies.
Hanko V, Apple AC, Alpert KI, Warren KN, Schneider JA, Arfanakis K, Bennett DA, Wang L
Neurobiology of aging. PubMed PMID: 30453234
Published date: 2018 Oct 25
Sex differences in Alzheimer's disease and common neuropathologies of aging.
Oveisgharan S, Arvanitakis Z, Yu L, Farfel J, Schneider JA, Bennett DA
Acta neuropathologica 136 (6):887-900. PubMed PMID: 30334074
Published date: 2018 Oct 17
APOE genotypes as a risk factor for age-dependent accumulation of cerebrovascular disease in older adults.
Lamar M, Yu L, Rubin LH, James BD, Barnes LL, Farfel JM, Gaiteri C, Buchman AS, Bennett DA, Schneider JA
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (2):258-266. PubMed PMID: 30321502
Published date: 2018 Oct 12
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
MahmoudianDehkordi S, Arnold M, Nho K, Ahmad S, Jia W, Xie G, Louie G, Kueider-Paisley A, Moseley MA, Thompson JW, St John Williams L, Tenenbaum JD, Blach C, Baillie R, Han X, Bhattacharyya S, Toledo JB, Schafferer S, Klein S, Koal T, Risacher SL, Kling M
Alzheimer's & dementia : the journal of the Alzheimer's Association 15 (1):76-92. PubMed PMID: 30337151
Published date: 2018 Oct 08
Integrative transcriptome analyses of the aging brain implicate altered splicing in Alzheimer's disease susceptibility.
Raj T, Li YI, Wong G, Humphrey J, Wang M, Ramdhani S, Wang YC, Ng B, Gupta I, Haroutunian V, Schadt EE, Young-Pearse T, Mostafavi S, Zhang B, Sklar P, Bennett DA, De Jager PL
Nature genetics 50 (11):1584-1592. PubMed PMID: 30297968
Published date: 2018 Oct 08
Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia?
Crum J, Wilson J, Sabbagh M
Alzheimer's research & therapy 10 (1):104. PubMed PMID: 30285877
Published date: 2018 10 02
Deconstructing and targeting the genomic architecture of human neurodegeneration.
De Jager PL, Yang HS, Bennett DA
Nature neuroscience 21 (10):1310-1317. PubMed PMID: 30258235
Published date: 2018 Oct
Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology.
Rangasamy SB, Jana M, Roy A, Corbett GT, Kundu M, Chandra S, Mondal S, Dasarathi S, Mufson EJ, Mishra RK, Luan CH, Bennett DA, Pahan K
The Journal of clinical investigation 128 (10):4297-4312. PubMed PMID: 29990310
Published date: 2018 10 01
Longitudinal associations between different dementia diagnoses and medication use jointly accounting for dropout.
Agogo GO, Ramsey CM, Gnjidic D, Moga DC, Allore H
International psychogeriatrics 30 (10):1477-1487. PubMed PMID: 29667565
Published date: 2018 10
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.
Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, B
Nature communications 9 (1):3945. PubMed PMID: 30258056
Published date: 2018 09 26
An MRI biomarker of mixed pathology.
Bennett DA
Neurology 91 (15):682-683. PubMed PMID: 30217934
Published date: 2018 Sep 14
Cognitive composite score association with Alzheimer's disease plaque and tangle pathology.
Malek-Ahmadi M, Chen K, Perez SE, He A, Mufson EJ
Alzheimer's research & therapy 10 (1):90. PubMed PMID: 30205840
Published date: 2018 09 11
The Impact of Dementia Diagnosis on Patterns of Potentially Inappropriate Medication Use Among Older Adults.
Gnjidic D, Agogo GO, Ramsey CM, Moga DC, Allore H
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (10):1410-1417. PubMed PMID: 29684111
Published date: 2018 09 11
Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects.
Ahmad F, Das D, Kommaddi RP, Diwakar L, Gowaikar R, Rupanagudi KV, Bennett DA, Ravindranath V
Scientific reports 8 (1):13119. PubMed PMID: 30177812
Published date: 2018 Sep 03
Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study.
Yang HS, Yu L, White CC, Chibnik LB, Chhatwal JP, Sperling RA, Bennett DA, Schneider JA, De Jager PL
The Lancet. Neurology 17 (9):773-781. PubMed PMID: 30093249
Published date: 2018 Sep
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts.
Lim ASP, Gaiteri C, Yu L, Sohail S, Swardfager W, Tasaki S, Schneider JA, Paquet C, Stuss DT, Masellis M, Black SE, Hugon J, Buchman AS, Barnes LL, Bennett DA, De Jager PL
PLoS medicine 15 (9):e1002647. PubMed PMID: 30180184
Published date: 2018 Sep
Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.
Tiernan CT, Ginsberg SD, He B, Ward SM, Guillozet-Bongaarts AL, Kanaan NM, Mufson EJ, Counts SE
Neurobiology of disease. PubMed PMID: 29859871
Published date: 2018 Sep
The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, De Jager P, Schneider JA, Morris CM, McKeith IG, Perry RH, Lovestone S, Woltjer RL
Brain : a journal of neurology 141 (9):2721-2739. PubMed PMID: 30137212
Published date: 2018 Aug 20
Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples
Molecular psychiatry. PubMed PMID: 30108311
Published date: 2018 Aug 14
Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease.
Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, Ikram MA, Mayeux R, Farrer LA, Haines JL, Pericak-Vance MA, Schellenbe
Neurobiology of aging. PubMed PMID: 30201328
Published date: 2018 Aug 09
A multi-omic atlas of the human frontal cortex for aging and Alzheimer's disease research.
De Jager PL, Ma Y, McCabe C, Xu J, Vardarajan BN, Felsky D, Klein HU, White CC, Peters MA, Lodgson B, Nejad P, Tang A, Mangravite LM, Yu L, Gaiteri C, Mostafavi S, Schneider JA, Bennett DA
Scientific data. PubMed PMID: 30084846
Published date: 2018 Aug 07
Chronic Health Illnesses as Predictors of Mild Cognitive Impairment Among African American Older Adults.
Burke SL, Cadet T, Maddux M
Journal of the National Medical Association 110 (4):314-325. PubMed PMID: 30126555
Published date: 2018 Aug
Cognitive and functional progression in Alzheimer disease: A prediction model of latent classes.
Haaksma ML, Caldern-Larraaga A, Olde Rikkert MGM, Melis RJF, Leoutsakos JS
International journal of geriatric psychiatry 33 (8):1057-1064. PubMed PMID: 29761569
Published date: 2018 08
Reproductive period and epigenetic modifications of the oxidative phosphorylation pathway in the human prefrontal cortex.
Bove RM, Patrick E, Aubin CM, Srivastava G, Schneider JA, Bennett DA, De Jager PL, Chibnik LB
PloS one 13 (7):e0199073. PubMed PMID: 30052629
Published date: 2018
Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain.
Felsky D, Patrick E, Schneider JA, Mostafavi S, Gaiteri C, Patsopoulos N, Bennett DA, De Jager PL
Molecular neurodegeneration 13 (1):38. PubMed PMID: 30041668
Published date: 2018 Jul 24
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.
Lee JJ, Wedow R, Okbay A, Kong E, Maghzian O, Zacher M, Nguyen-Viet TA, Bowers P, Sidorenko J, Karlsson Linnr R, Fontana MA, Kundu T, Lee C, Li H, Li R, Royer R, Timshel PN, Walters RK, Willoughby EA, Yengo L, Alver M, Bao Y, Clark DW, Day FR, Furlotte NA
Nature genetics 50 (8):1112-1121. PubMed PMID: 30038396
Published date: 2018 07 23
Integrative DNA copy number detection and genotyping from sequencing and array-based platforms.
Zhou Z, Wang W, Wang LS, Zhang NR
Bioinformatics (Oxford, England) 34 (14):2349-2355. PubMed PMID: 29992253
Published date: 2018 07 15
Late-life blood pressure association with cerebrovascular and Alzheimer disease pathology.
Arvanitakis Z, Capuano AW, Lamar M, Shah RC, Barnes LL, Bennett DA, Schneider JA
Neurology 91 (6):e517-e525. PubMed PMID: 29997190
Published date: 2018 Jul 11
White matter correlates of temporal discounting in older adults.
Han SD, Arfanakis K, Fleischman DA, Yu L, Bennett DA, Boyle PA
Brain structure & function 223 (8):3653-3663. PubMed PMID: 29992469
Published date: 2018 Jul 10
Repression of human and mouse brain inflammaging transcriptome by broad gene-body histone hyperacetylation.
Cheng H, Xuan H, Green CD, Han Y, Sun N, Shen H, McDermott J, Bennett DA, Lan F, Han JJ
Proceedings of the National Academy of Sciences of the United States of America 115 (29):7611-7616. PubMed PMID: 29967166
Published date: 2018 Jul 02
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, John
Acta neuropathologica 136 (6):857-872. PubMed PMID: 29967939
Published date: 2018 Jul 02
Neopterin is associated with hippocampal subfield volumes and cognition in HIV.
Fleischman DA, Arfanakis K, Leurgans S, Keating SM, Lamar M, Bennett DA, Adeyemi OM, Barnes LL
Neurology(R) neuroimmunology & neuroinflammation 5 (4):e467. PubMed PMID: 29904644
Published date: 2018 Jul
Psychosis in "Cognitively Asymptomatic" Elderly Subjects is Associated With Neuritic Plaque Load, Not Neurofibrillary Tangles.
Kim J, Schweizer TA, Fischer CE, Munoz DG
Alzheimer disease and associated disorders 32 (3):185-189. PubMed PMID: 29553944
Published date: 2018 Jul-Sep
Combined neuropathological pathways account for age-related risk of dementia.
Power MC, Mormino E, Soldan A, James BD, Yu L, Armstrong NM, Bangen KJ, Delano-Wood L, Lamar M, Lim YY, Nudelman K, Zahodne L, Gross AL, Mungas D, Widaman KF, Schneider J
Annals of neurology 84 (1):10-22. PubMed PMID: 29944741
Published date: 2018 07
Analysis of shared heritability in common disorders of the brain.
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amou
Science (New York, N.Y.). PubMed PMID: 29930110
Published date: 2018 06 22
Gene expression and DNA methylation are extensively coordinated with MRI-based brain microstructural characteristics.
Gaiteri C, Dawe R, Mostafavi S, Blizinsky KD, Tasaki S, Komashko V, Yu L, Wang Y, Schneider JA, Arfanakis K, De Jager PL, Bennett DA
Brain imaging and behavior 13 (4):963-972. PubMed PMID: 29934819
Published date: 2018 Jun 22
Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.
Readhead B, Haure-Mirande JV, Funk CC, Richards MA, Shannon P, Haroutunian V, Sano M, Liang WS, Beckmann ND, Price ND, Reiman EM, Schadt EE, Ehrlich ME, Gandy S, Dudley JT
Neuron 99 (1):64-82.e7. PubMed PMID: 29937276
Published date: 2018 Jun 21
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
Yu L, Petyuk VA, Gaiteri C, Mostafavi S, Young-Pearse T, Shah RC, Buchman AS, Schneider JA, Piehowski PD, Sontag RL, Fillmore TL, Shi T, Smith RD, De Jager PL, Bennett DA
Annals of neurology 84 (1):78-88. PubMed PMID: 29908079
Published date: 2018 Jun 16
Predictive Modeling of the Progression of Alzheimer's Disease with Recurrent Neural Networks.
Wang T, Qiu RG, Yu M
Scientific reports 8 (1):9161. PubMed PMID: 29907747
Published date: 2018 06 15
Landscape of Conditional eQTL in Dorsolateral Prefrontal Cortex and Co-localization with Schizophrenia GWAS.
Dobbyn A, Huckins LM, Boocock J, Sloofman LG, Glicksberg BS, Giambartolomei C, Hoffman GE, Perumal TM, Girdhar K, Jiang Y, Raj T, Ruderfer DM, Kramer RS, Pinto D, Akbarian S, Roussos P, Domenici E, Devlin B, Sklar P, Stahl EA, Sieberts SK
American journal of human genetics 102 (6):1169-1184. PubMed PMID: 29805045
Published date: 2018 Jun 07
Tau Activates Transposable Elements in Alzheimer's Disease.
Guo C, Jeong HH, Hsieh YC, Klein HU, Bennett DA, De Jager PL, Liu Z, Shulman JM
Cell reports 23 (10):2874-2880. PubMed PMID: 29874575
Published date: 2018 Jun 05
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer's disease.
Mostafavi S, Gaiteri C, Sullivan SE, White CC, Tasaki S, Xu J, Taga M, Klein HU, Patrick E, Komashko V, McCabe C, Smith R, Bradshaw EM, Root DE, Regev A, Yu L, Chibnik LB, Schneider JA, Young-Pearse TL, Bennett DA, De Jager PL
Nature neuroscience 21 (6):811-819. PubMed PMID: 29802388
Published date: 2018 Jun
Watershed microinfarct pathology and cognition in older persons.
Kapasi A, Leurgans SE, James BD, Boyle PA, Arvanitakis Z, Nag S, Bennett DA, Buchman AS, Schneider JA
Neurobiology of aging. PubMed PMID: 29935416
Published date: 2018 May 30
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.
Davies G, Lam M, Harris SE, Trampush JW, Luciano M, Hill WD, Hagenaars SP, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Liewald DCM, Okely JA, Ahola-Olli AV, Barnes CLK, Bertram L, Bis JC, Burdick KE, Christoforou A, DeRosse P, Djurovic S, Espeseth T, Giakoum
Nature communications 9 (1):2098. PubMed PMID: 29844566
Published date: 2018 May 29
Religious Orders Study and Rush Memory and Aging Project.
Bennett DA, Buchman AS, Boyle PA, Barnes LL, Wilson RS, Schneider JA
Journal of Alzheimer's disease : JAD 64 (s1):S161-S189. PubMed PMID: 29865057
Published date: 2018 May 26
Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults.
Dawe RJ, Yu L, Schneider JA, Arfanakis K, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29908416
Published date: 2018 May 23
APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.
Oveisgharan S, Buchman AS, Yu L, Farfel J, Hachinski V, Gaiteri C, De Jager PL, Schneider JA, Bennett DA
Neurology 90 (24):e2127-e2134. PubMed PMID: 29752306
Published date: 2018 May 11
Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
Hohman TJ, Dumitrescu L, Barnes LL, Thambisetty M, Beecham G, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnso
JAMA neurology 75 (8):989-998. PubMed PMID: 29801024
Published date: 2018 May 07
TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer's disease.
Nag S, Yu L, Boyle PA, Leurgans SE, Bennett DA, Schneider JA
Acta neuropathologica communications 6 (1):33. PubMed PMID: 29716643
Published date: 2018 May 01
Positional effects revealed in Illumina methylation array and the impact on analysis.
Jiao C, Zhang C, Dai R, Xia Y, Wang K, Giase G, Chen C, Liu C
Epigenomics 10 (5):643-659. PubMed PMID: 29469594
Published date: 2018 05
An epigenetic biomarker of aging for lifespan and healthspan.
Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, Liu Y, Ferrucci L, Horvath S
Aging 10 (4):573-591. PubMed PMID: 29676998
Published date: 2018 04 18
Sexual dimorphism in predisposition to Alzheimer's disease.
Fisher DW, Bennett DA, Dong H
Neurobiology of aging. PubMed PMID: 29754747
Published date: 2018 Apr 17
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.
Jack CR, Bennett DA, Blennow K, Carrillo MC, Dunn B, Haeberlein SB, Holtzman DM, Jagust W, Jessen F, Karlawish J, Liu E, Molinuevo JL, Montine T, Phelps C, Rankin KP, Rowe CC, Scheltens P, Siemers E, Snyder HM, Sperling R
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (4):535-562. PubMed PMID: 29653606
Published date: 2018 Apr
Testing Tele-Savvy: Protocol for a randomized controlled trial.
Kovaleva MA, Bilsborough E, Griffiths PC, Nocera J, Higgins M, Epps F, Kilgore K, Lindauer A, Morhardt D, Shah RC, Hepburn K
Research in nursing & health 41 (2):107-120. PubMed PMID: 29399825
Published date: 2018 Apr
Integrated biology approach reveals molecular and pathological interactions among Alzheimer's Aβ42, Tau, TREM2, and TYROBP in Drosophila models.
Sekiya M, Wang M, Fujisaki N, Sakakibara Y, Quan X, Ehrlich ME, De Jager PL, Bennett DA, Schadt EE, Gandy S, Ando K, Zhang B, Iijima KM
Genome medicine 10 (1):26. PubMed PMID: 29598827
Published date: 2018 Mar 29
Neurodegenerative disease and cognitive retest learning.
Wilson RS, Capuano AW, Yu L, Yang J, Kim N, Leurgans SE, Lamar M, Schneider JA, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29558667
Published date: 2018 Mar 17
Time-to-event data with time-varying biomarkers measured only at study entry, with applications to Alzheimer's disease.
Lee C, Betensky RA
Statistics in medicine 37 (6):914-932. PubMed PMID: 29266591
Published date: 2018 Mar 15
Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, Lunnon K
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (12):1580-1588. PubMed PMID: 29550519
Published date: 2018 Mar 14
A Bayesian Framework for Generalized Linear Mixed Modeling Identifies New Candidate Loci for Late-Onset Alzheimer's Disease.
Wang X, Philip VM, Ananda G, White CC, Malhotra A, Michalski PJ, Karuturi KRM, Chintalapudi SR, Acklin C, Sasner M, Bennett DA, De Jager PL, Howell GR, Carter GW
Genetics 209 (1):51-64. PubMed PMID: 29507048
Published date: 2018 Mar 05
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.
Montagne A, Nikolakopoulou AM, Zhao Z, Sagare AP, Si G, Lazic D, Barnes SR, Daianu M, Ramanathan A, Go A, Lawson EJ, Wang Y, Mack WJ, Thompson PM, Schneider JA, Varkey J, Langen R, Mullins E, Jacobs RE, Zlokovic BV
Nature medicine 24 (3):326-337. PubMed PMID: 29400711
Published date: 2018 03
Tau Oligomer Pathology in Nucleus Basalis Neurons During the Progression of Alzheimer Disease.
Tiernan CT, Mufson EJ, Kanaan NM, Counts SE
Journal of neuropathology and experimental neurology 77 (3):246-259. PubMed PMID: 29378005
Published date: 2018 03 01
Do subjects with minimal motor features have prodromal Parkinson disease?
Chu Y, Buchman AS, Olanow CW, Kordower JH
Annals of neurology 83 (3):562-574. PubMed PMID: 29420861
Published date: 2018 Mar
A Common DIO2 Polymorphism and Alzheimer Disease Dementia in African and European Americans.
McAninch EA, Rajan KB, Evans DA, Jo S, Chaker L, Peeters RP, Bennett DA, Mash DC, Bianco AC
The Journal of clinical endocrinology and metabolism 103 (5):1818-1826. PubMed PMID: 29481662
Published date: 2018 Feb 22
Memory complaints, dementia, and neuropathology in older blacks and whites.
Arvanitakis Z, Leurgans SE, Fleischman DA, Schneider JA, Rajan KB, Pruzin JJ, Shah RC, Evans DA, Barnes LL, Bennett DA
Annals of neurology 83 (4):718-729. PubMed PMID: 29466839
Published date: 2018 Feb 21
Alzheimer disease biomarkers and synucleinopathy.
Bennett DA, Gordon BA
Neurology 90 (12):537-538. PubMed PMID: 29467302
Published date: 2018 Feb 21
Longitudinal Modeling of Functional Decline Associated with Pathologic Alzheimer's Disease in Older Persons without Cognitive Impairment.
Wang D, Schultz T, Novak GP, Baker S, Bennett DA, Narayan VA
Journal of Alzheimer's disease : JAD 62 (2):855-865. PubMed PMID: 29480187
Published date: 2018
Static and Dynamic Cognitive Reserve Proxy Measures: Interactions with Alzheimer's Disease Neuropathology and Cognition.
Malek-Ahmadi M, Lu S, Chan Y, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease & Parkinsonism. PubMed PMID: 29423338
Published date: 2017
Circulating Dkk1 and TRAIL Are Associated With Cognitive Decline in Community-Dwelling, Older Adults With Cognitive Concerns.
Ross RD, Shah RC, Leurgans S, Bottligieri T, Wilson RS, Sumner DR
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (12):1688-1694. PubMed PMID: 29432613
Published date: 2018 Feb 08
The Stress-Induced Transcription Factor NR4A1 Adjusts Mitochondrial Function and Synapse Number in Prefrontal Cortex.
Jeanneteau F, Barre?re C, Vos M, De Vries CJM, Rouillard C, Levesque D, Dromard Y, Moisan MP, Duric V, Franklin TC, Duman RS, Lewis DA, Ginsberg SD, Arango-Lievano M
The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (6):1335-1350. PubMed PMID: 29295823
Published date: 2018 Feb 07
A transcriptomic atlas of aged human microglia.
Olah M, Patrick E, Villani AC, Xu J, White CC, Ryan KJ, Piehowski P, Kapasi A, Nejad P, Cimpean M, Connor S, Yung CJ, Frangieh M, McHenry A, Elyaman W, Petyuk V, Schneider JA, Bennett DA, De Jager PL, Bradshaw EM
Nature communications 9 (1):539. PubMed PMID: 29416036
Published date: 2018 Feb 07
Tau induces blood vessel abnormalities and angiogenesis-related gene expression in P301L transgenic mice and human Alzheimer's disease.
Bennett RE, Robbins AB, Hu M, Cao X, Betensky RA, Clark T, Das S, Hyman BT
Proceedings of the National Academy of Sciences of the United States of America 115 (6):E1289-E1298. PubMed PMID: 29358399
Published date: 2018 02 06
CYP2C19 variant mitigates Alzheimer disease pathophysiology in vivo and postmortem.
Benedet AL, Yu L, Labbe A, Mathotaarachchi S, Pascoal TA, Shin M, Kang MS, Gauthier S, Rouleau GA, Poirier J, Bennett DA, Rosa-Neto P
Neurology. Genetics 4 (1):e216. PubMed PMID: 29473050
Published date: 2018 Feb
Transitions across cognitive states and death among older adults in relation to education: A multistate survival model using data from six longitudinal studies.
Robitaille A, van den Hout A, Machado RJM, Bennett DA, C?ukic? I, Deary IJ, Hofer SM, Hoogendijk EO, Huisman M, Johansson B, Koval AV, van der Noordt M, Piccinin AM, Rijnhart JJM, Singh-Manoux A, Skoog J, Skoog I, Starr J, Vermunt L, Clouston S, Muniz Ter
Alzheimer's & dementia : the journal of the Alzheimer's Association 14 (4):462-472. PubMed PMID: 29396108
Published date: 2018 Jan 25
Evaluation of standardized and study-specific diffusion tensor imaging templates of the adult human brain: Template characteristics, spatial normalization accuracy, and detection of small inter-group
Zhang S, Arfanakis K
NeuroImage. PubMed PMID: 29414497
Published date: 2018 Jan 24
Lack of Benefit With Idalopirdine for Alzheimer Disease: Another Therapeutic Failure in a Complex Disease Process.
Bennett DA
JAMA 319 (2):123-125. PubMed PMID: 29318261
Published date: 2018 01 09
Bivariate Causal Discovery and Its Applications to Gene Expression and Imaging Data Analysis.
Jiao R, Lin N, Hu Z, Bennett DA, Jin L, Xiong M
Frontiers in genetics. PubMed PMID: 30233639
Published date: 2018
The Association Between Body Mass Index, and Cognitive, Functional, and Behavioral Declines for Incident Dementia.
Michaud TL, Siahpush M, Farazi PA, Kim J, Yu F, Su D, Murman DL
Journal of Alzheimer's disease : JAD 66 (4):1507-1517. PubMed PMID: 30412484
Published date: 2018
Traumatic Brain Injury and Age of Onset of Dementia with Lewy Bodies.
Nguyen TP, Schaffert J, LoBue C, Womack KB, Hart J, Cullum CM
Journal of Alzheimer's disease : JAD 66 (2):717-723. PubMed PMID: 30320582
Published date: 2018
Estimating the monetary benefits of medicare eligibility for reducing the symptoms of dementia.
Brent RJ
Applied economics 50 (58):6327-6340. PubMed PMID: 30344332
Published date: 2018
Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.
Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C
Journal of Alzheimer's disease : JAD 64 (2):631-642. PubMed PMID: 29914016
Published date: 2018
Ezrin Expression is Increased During Disease Progression in a Tauopathy Mouse Model and Alzheimer's Disease.
Vega IE, Umstead A, Wygant CM, Beck JS, Counts SE
Current Alzheimer research 15 (12):1086-1095. PubMed PMID: 30101710
Published date: 2018
Potential Factors Associated with Cognitive Improvement of Individuals Diagnosed with Mild Cognitive Impairment or Dementia in Longitudinal Studies.
Hadjichrysanthou C, McRae-McKee K, Evans S, de Wolf F, Anderson RM
Journal of Alzheimer's disease : JAD 66 (2):587-600. PubMed PMID: 30320573
Published date: 2018
Pathologically Confirmed Alzheimer's Disease in APOE 2 Homozygotes is Rare but Does Occur.
Stipho F, Jackson R, Sabbagh MN
Journal of Alzheimer's disease : JAD 62 (4):1527-1530. PubMed PMID: 29562509
Published date: 2018
Neuropsychiatric Symptoms and the Diagnostic Stability of Mild Cognitive Impairment.
Sugarman MA, Alosco ML, Tripodis Y, Steinberg EG, Stern RA
Journal of Alzheimer's disease : JAD 62 (4):1841-1855. PubMed PMID: 29614641
Published date: 2018
Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease.
Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC
Journal of Alzheimer's disease : JAD 62 (4):1815-1826. PubMed PMID: 29614657
Published date: 2018
Impact of the Presence of Select Cardiovascular Risk Factors on Cognitive Changes among Dementia Subtypes.
Irimata KE, Dugger BN, Wilson JR
Current Alzheimer research 15 (11):1032-1044. PubMed PMID: 29962344
Published date: 2018
Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project.
Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, Jun G, Kunkle B, Kuzma A, Lee JJ, Lunetta KL, Ma Y, Martin E, Naj A, Nato AQ, Navas P, Nguy
Dementia and geriatric cognitive disorders 45 (1-2):1-17. PubMed PMID: 29486463
Published date: 2018
The Molecular and Neuropathological Consequences of Genetic Risk for Alzheimer's Dementia.
Tasaki S, Gaiteri C, Mostafavi S, De Jager PL, Bennett DA
Frontiers in neuroscience. PubMed PMID: 30349450
Published date: 2018
Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly.
Lee S, Zhou X, Gao Y, Vardarajan B, Reyes-Dumeyer D, Rajan KB, Wilson RS, Evans DA, Besser LM, Kukull WA, Bennett DA, Brickman AM, Schupf N, Mayeux R, Barral S
PloS one 13 (11):e0206803. PubMed PMID: 30462667
Published date: 2018
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
Peloso GM, van der Lee SJ, Destefano AL, Seshardi S
Alzheimer's & dementia (Amsterdam, Netherlands). PubMed PMID: 30422133
Published date: 2018
The Added Value of Diffusion-Weighted MRI-Derived Structural Connectome in Evaluating Mild Cognitive Impairment: A Multi-Cohort Validation1.
Wang Q, Guo L, Thompson PM, Jack CR, Dodge H, Zhan L, Zhou J
Journal of Alzheimer's disease : JAD 64 (1):149-169. PubMed PMID: 29865049
Published date: 2018
A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology.
Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA
Journal of Alzheimer's disease : JAD 63 (4):1347-1360. PubMed PMID: 29843242
Published date: 2018
Rapidly Progressive Alzheimer's Disease inTwo Distinct Autopsy Cohorts.
Pillai JA, Appleby BS, Safar J, Leverenz JB
Journal of Alzheimer's disease : JAD 64 (3):973-980. PubMed PMID: 29966195
Published date: 2018
Population Neuroscience: Dementia Epidemiology Serving Precision Medicine and Population Health.
Ganguli M, Albanese E, Seshadri S, Bennett DA, Lyketsos C, Kukull WA, Skoog I, Hendrie HC
Alzheimer disease and associated disorders 32 (1):1-9. PubMed PMID: 29319603
Published date: 2018 Jan-Mar
Best practices and lessons learned from reuse of 4 patient-derived metabolomics datasets in Alzheimer's disease.
Tenenbaum JD, Blach C
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. PubMed PMID: 29218889
Published date: 2018
Frontal Cortex Epigenetic Dysregulation During the Progression of Alzheimer's Disease.
Mahady L, Nadeem M, Malek-Ahmadi M, Chen K, Perez SE, Mufson EJ
Journal of Alzheimer's disease : JAD 62 (1):115-131. PubMed PMID: 29439356
Published date: 2018
Multi-omic Directed Networks Describe Features of Gene Regulation in Aged Brains and Expand the Set of Genes Driving Cognitive Decline.
Tasaki S, Gaiteri C, Mostafavi S, Yu L, Wang Y, De Jager PL, Bennett DA
Frontiers in genetics. PubMed PMID: 30140277
Published date: 2018
Case-control studies of gene-environment interactions. When a case might not be the case.
Lobach I, Sampson J, Alekseyenko A, Lobach S, Zhang L
PloS one 13 (8):e0201140. PubMed PMID: 30133451
Published date: 2018
Bivariate Genome-Wide Association Study of Depressive Symptoms With Type 2 Diabetes and Quantitative Glycemic Traits.
Haljas K, Amare AT, Alizadeh BZ, Hsu YH, Mosley T, Newman A, Murabito J, Tiemeier H, Tanaka T, van Duijn C, Ding J, Llewellyn DJ, Bennett DA, Terracciano A, Launer L, Ladwig KH, Cornelis MC, Teumer A, Grabe H, Kardia SLR, Ware EB, Smith JA, Snieder H, Eri
Psychosomatic medicine 80 (3):242-251. PubMed PMID: 29280852
Published date: 2017 Dec 27
Ex-vivo quantitative susceptibility mapping of human brain hemispheres.
Evia AM, Kotrotsou A, Tamhane AA, Dawe RJ, Kapasi A, Leurgans SE, Schneider JA, Bennett DA, Arfanakis K
PloS one 12 (12):e0188395. PubMed PMID: 29261693
Published date: 2017
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants.
Ryan KJ, White CC, Patel K, Xu J, Olah M, Replogle JM, Frangieh M, Cimpean M, Winn P, McHenry A, Kaskow BJ, Chan G, Cuerdon N, Bennett DA, Boyd JD, Imitola J, Elyaman W, De Jager PL, Bradshaw EM
Science translational medicine. PubMed PMID: 29263232
Published date: 2017 Dec 20
Person-specific contribution of neuropathologies to cognitive loss in old age.
Boyle PA, Yu L, Wilson RS, Leurgans SE, Schneider JA, Bennett DA
Annals of neurology 83 (1):74-83. PubMed PMID: 29244218
Published date: 2017 Dec 15
Aβ mediates F-actin disassembly in dendritic spines leading to cognitive deficits in Alzheimer's disease.
Peera Kommaddi R, Das D, Karunakaran S, Nanguneri S, Bapat D, Ray A, Shaw E, Bennett DA, Nair D, Ravindranath V
The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (5):1085-1099. PubMed PMID: 29246925
Published date: 2017 Dec 15
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity.
Sorrentino V, Romani M, Mouchiroud L, Beck JS, Zhang H, D'Amico D, Moullan N, Potenza F, Schmid AW, Rietsch S, Counts SE, Auwerx J
Nature 552 (7684):187-193. PubMed PMID: 29211722
Published date: 2017 12 14
Inventory of real world data sources in Parkinson's disease.
Tanguy A, Jo?nsson L, Ishihara L
BMC neurology 17 (1):213. PubMed PMID: 29216834
Published date: 2017 Dec 08
A variant in PPP4R3A protects against alzheimer-related metabolic decline.
Christopher L, Napolioni V, Khan RR, Han SS, Greicius MD
Annals of neurology 82 (6):900-911. PubMed PMID: 29130521
Published date: 2017 Dec
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan
Acta neuropathologica 135 (1):85-93. PubMed PMID: 29177679
Published date: 2017 Nov 24
Specific serum antibody binding to phosphorylated and non-phosphorylated tau in non-cognitively impaired, mildly cognitively impaired, and Alzheimer's disease subjects: an exploratory study.
Klaver AC, Coffey MP, Bennett DA, Loeffler DA
Translational neurodegeneration. PubMed PMID: 29204273
Published date: 2017
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL
Stem cell reports 9 (6):1868-1884. PubMed PMID: 29153990
Published date: 2017 Nov 13
Alzheimer's Disease-Related Dementias Summit 2016: National research priorities.
Corriveau RA, Koroshetz WJ, Gladman JT, Jeon S, Babcock D, Bennett DA, Carmichael ST, Dickinson SL, Dickson DW, Emr M, Fillit H, Greenberg SM, Hutton ML, Knopman DS, Manly JJ, Marder KS, Moy CS, Phelps CH, Scott PA, Seeley WW, Sieber BA, Silverberg NB, Su
Neurology 89 (23):2381-2391. PubMed PMID: 29117955
Published date: 2017 Nov 08
Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline.
Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA
JAMA neurology 74 (12):1473-1480. PubMed PMID: 29084334
Published date: 2017 Oct 30
Genetic influence of plasma homocysteine on Alzheimer's disease.
Roostaei T, Felsky D, Nazeri A, De Jager PL, Schneider JA, Bennett DA, Voineskos AN
Neurobiology of aging. PubMed PMID: 29102475
Published date: 2017 Oct 13
Traumatic brain injury may not increase the risk of Alzheimer disease.
Weiner MW, Crane PK, Montine TJ, Bennett DA, Veitch DP
Neurology 89 (18):1923-1925. PubMed PMID: 28978654
Published date: 2017 Oct 04
Ultra-rare mutations in
Vardarajan BN, Tosto G, Lefort R, Yu L, Bennett DA, De Jager PL, Barral S, Reyes-Dumeyer D, Nagy PL, Lee JH, Cheng R, Medrano M, Lantigua R, Rogaeva E, St George-Hyslop P, Mayeux R
Neurology. Genetics 3 (5):e178. PubMed PMID: 28852706
Published date: 2017 Oct
Personality Predicts Mortality Risk: An Integrative Data Analysis of 15 International Longitudinal Studies.
Graham EK, Rutsohn JP, Turiano NA, Bendayan R, Batterham PJ, Gerstorf D, Katz MJ, Reynolds CA, Sharp ES, Yoneda TB, Bastarache ED, Elleman LG, Zelinski EM, Johansson B, Kuh D, Barnes LL, Bennett DA, Deeg DJH, Lipton RB, Pedersen NL, Piccinin AM, Spiro A,
Journal of research in personality. PubMed PMID: 29230075
Published date: 2017 Oct
Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impai
Ginsberg SD, Malek-Ahmadi MH, Alldred MJ, Che S, Elarova I, Chen Y, Jeanneteau F, Kranz TM, Chao MV, Counts SE, Mufson EJ
Hippocampus 29 (5):422-439. PubMed PMID: 28888073
Published date: 2017 Sep 09
Age and the association of dementia-related pathology with trajectories of cognitive decline.
Jansen WJ, Wilson RS, Visser PJ, Nag S, Schneider JA, James BD, Leurgans SE, Capuano AW, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 29078129
Published date: 2017 Sep 05
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome.
Ng B, White CC, Klein HU, Sieberts SK, McCabe C, Patrick E, Xu J, Yu L, Gaiteri C, Bennett DA, Mostafavi S, De Jager PL
Nature neuroscience 20 (10):1418-1426. PubMed PMID: 28869584
Published date: 2017 Sep 04
Cognitive Aging in Black and White Americans: Cognition, Cognitive Decline, and Incidence of Alzheimer Disease Dementia.
Weuve J, Barnes LL, de Leon CFM, Rajan KB, Beck T, Aggarwal NT, Hebert LE, Bennett DA, Wilson RS, Evans DA
Epidemiology (Cambridge, Mass.) 29 (1):151-159. PubMed PMID: 28863046
Published date: 2017 Aug 31
Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain.
Barbash S, Simchovitz A, Buchman AS, Bennett DA, Shifman S, Soreq H
Translational psychiatry 7 (8):e1199. PubMed PMID: 28786976
Published date: 2017 Aug 08
Body Mass Index and Decline in Cognitive Function in Older Black and White Persons.
Arvanitakis Z, Capuano AW, Bennett DA, Barnes LL
The journals of gerontology. Series A, Biological sciences and medical sciences 73 (2):198-203. PubMed PMID: 28961897
Published date: 2017 Aug 07
Impact of multiple pathologies on the threshold for clinically overt dementia.
Kapasi A, DeCarli C, Schneider JA
Acta neuropathologica 134 (2):171-186. PubMed PMID: 28488154
Published date: 2017 Aug
UNC5C variants are associated with cerebral amyloid angiopathy.
Yang HS, White CC, Chibnik LB, Klein HU, Schneider JA, Bennett DA, De Jager PL
Neurology. Genetics 3 (4):e176. PubMed PMID: 28761931
Published date: 2017 Aug
Frontal Cortex and Hippocampal γ-Secretase Activating Protein Levels in Prodromal Alzheimer Disease.
Perez SE, Nadeem M, Malek-Ahmadi MH, He B, Mufson EJ
Neuro-degenerative diseases 17 (6):235-241. PubMed PMID: 28743126
Published date: 2017 Jul 26
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P,
Nature genetics 49 (9):1373-1384. PubMed PMID: 28714976
Published date: 2017 Jul 17
APOE ε4-TOMM40 '523 haplotypes and the risk of Alzheimer's disease in older Caucasian and African Americans.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Yang J, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
PloS one 12 (7):e0180356. PubMed PMID: 28672022
Published date: 2017
Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer's disease.
Patrick E, Rajagopal S, Wong HA, McCabe C, Xu J, Tang A, Imboywa SH, Schneider JA, Pochet N, Krichevsky AM, Chibnik LB, Bennett DA, De Jager PL
Molecular neurodegeneration 12 (1):51. PubMed PMID: 28668092
Published date: 2017 Jul 01
Loss of precuneus dendritic spines immunopositive for spinophilin is related to cognitive impairment in early Alzheimer's disease.
Mi Z, Abrahamson EE, Ryu AY, Fish KN, Sweet RA, Mufson EJ, Ikonomovic MD
Neurobiology of aging. PubMed PMID: 28259365
Published date: 2017 Jul
Preventing Cognitive Decline and Dementia: A Way Forward
Downey A, Stroud C, Landis S, Leshner AI
null 84 (1):78-88. PubMed PMID: 28650595
Published date: 2017 06 22
Alzheimer's brains show inter-related changes in RNA and lipid metabolism.
Barbash S, Garfinkel BP, Maoz R, Simchovitz A, Nadorp B, Guffanti A, Bennett ER, Nadeau C, Tu?rk A, Paul L, Reda T, Li Y, Buchman AS, Greenberg DS, Seitz A, Bennett DA, Giavalisco P, Soreq H
Neurobiology of disease. PubMed PMID: 28630030
Published date: 2017 Jun 16
Neuropathologic features of TOMM40 '523 variant on late-life cognitive decline.
Yu L, Lutz MW, Farfel JM, Wilson RS, Burns DK, Saunders AM, De Jager PL, Barnes LL, Schneider JA, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 9 (12):430. PubMed PMID: 28624335
Published date: 2017 Jun 15
A Dopamine Receptor genetic variant enhances perceptual speed in cognitive healthy subjects.
Barral S, Habeck C, Gazes E, De Jager PL, Bennett DA, Stern Y
Alzheimer's & dementia (New York, N. Y.) 3 (2):254-261. PubMed PMID: 28993814
Published date: 2017 Jun
Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease.
Perez SE, Nadeem M, He B, Miguel JC, Malek-Ahmadi MH, Chen K, Mufson EJ
Neurobiology of aging. PubMed PMID: 28365005
Published date: 2017 Jun
How Does Psychosocial Behavior Contribute to Cognitive Health in Old Age?
Wilson RS, Bennett DA
Brain sciences. PubMed PMID: 28545247
Published date: 2017 May 23
Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits.
Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesne? SE
Proceedings of the National Academy of Sciences of the United States of America 114 (23):E4648-E4657. PubMed PMID: 28533388
Published date: 2017 May 22
Genetic architecture of epigenetic and neuronal ageing rates in human brain regions.
Lu AT, Hannon E, Levine ME, Crimmins EM, Lunnon K, Mill J, Geschwind DH, Horvath S
Nature communications. PubMed PMID: 28516910
Published date: 2017 05 18
Cognitive Domain Dispersion Association with Alzheimer's Disease Pathology.
Malek-Ahmadi M, Lu S, Chan Y, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease : JAD 58 (2):575-583. PubMed PMID: 28453479
Published date: 2017
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers.
Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Kim S, Saykin AJ, De Jager PL, Albert M, Moghekar A, O'Brien R, Riemensc
Acta neuropathologica 133 (5):839-856. PubMed PMID: 28247064
Published date: 2017 May
Regulator of Cell Cycle (RGCC) Expression During the Progression of Alzheimer's Disease.
Counts SE, Mufson EJ
Cell transplantation 26 (4):693-702. PubMed PMID: 27938491
Published date: 2017 Apr 13
Reactive Oxygen Species-Mediated Loss of Synaptic Akt1 Signaling Leads to Deficient Activity-Dependent Protein Translation Early in Alzheimer's Disease.
Ahmad F, Singh K, Das D, Gowaikar R, Shaw E, Ramachandran A, Rupanagudi KV, Kommaddi RP, Bennett DA, Ravindranath V
Antioxidants & redox signaling 27 (16):1269-1280. PubMed PMID: 28264587
Published date: 2017 Apr 12
Diurnal and seasonal molecular rhythms in human neocortex and their relation to Alzheimer's disease.
Lim AS, Klein HU, Yu L, Chibnik LB, Ali S, Xu J, Bennett DA, De Jager PL
Nature communications. PubMed PMID: 28368004
Published date: 2017 Apr 03
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data.
White CC, Yang HS, Yu L, Chibnik LB, Dawe RJ, Yang J, Klein HU, Felsky D, Ramos-Miguel A, Arfanakis K, Honer WG, Sperling RA, Schneider JA, Bennett DA, De Jager PL
PLoS medicine 14 (4):e1002287. PubMed PMID: 28441426
Published date: 2017 Apr
Ex vivo MRI transverse relaxation in community based older persons with and without Alzheimer's dementia.
Yu L, Dawe RJ, Buchman AS, Boyle PA, Schneider JA, Arfanakis K, Bennett DA
Behavioural brain research 322 (Pt B):233-240. PubMed PMID: 27596378
Published date: 2017 Mar 30
Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies.
Chibnik LB, White CC, Mukherjee S, Raj T, Yu L, Larson EB, Montine TJ, Keene CD, Sonnen J, Schneider JA, Crane PK, Shulman JM, Bennett DA, De Jager PL
Molecular psychiatry 23 (6):1521-1529. PubMed PMID: 28322283
Published date: 2017 Mar 21
Polygenic risk scores in familial Alzheimer disease.
Tosto G, Bird TD, Tsuang D, Bennett DA, Boeve BF, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Bertlesen S, Graff-Radford NR, Medrano M, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R
Neurology 88 (12):1180-1186. PubMed PMID: 28213371
Published date: 2017 Mar 21
Genetic epistasis regulates amyloid deposition in resilient aging.
Felsky D, Xu J, Chibnik LB, Schneider JA, Knight J, Kennedy JL, Bennett DA, De Jager PL, Voineskos AN
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (10):1107-1116. PubMed PMID: 28322202
Published date: 2017 Mar 17
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Va
PLoS medicine 14 (3):e1002258. PubMed PMID: 28323831
Published date: 2017 03
Mixed pathologies and neural reserve: Implications of complexity for Alzheimer disease drug discovery.
Bennett DA
PLoS medicine 14 (3):e1002256. PubMed PMID: 28291788
Published date: 2017 Mar
Author response: Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Bennett DA
Neurology 88 (9):920. PubMed PMID: 28242853
Published date: 2017 Feb 28
Author response: Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Bennett DA
Neurology 88 (9):919-920. PubMed PMID: 28242851
Published date: 2017 Feb 28
Outcomes after diagnosis of mild cognitive impairment in a large autopsy series.
Abner EL, Kryscio RJ, Schmitt FA, Fardo DW, Moga DC, Ighodaro ET, Jicha GA, Yu L, Dodge HH, Xiong C, Woltjer RL, Schneider JA, Cairns NJ, Bennett DA, Nelson PT
Annals of neurology 81 (4):549-559. PubMed PMID: 28224671
Published date: 2017 Feb 22
Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease.
Geifman N, Brinton RD, Kennedy RE, Schneider LS, Butte AJ
Alzheimer's research & therapy 9 (1):10. PubMed PMID: 28212683
Published date: 2017 Feb 17
TOMM40'523 variant and cognitive decline in older persons with APOE ?3/3 genotype.
Yu L, Lutz MW, Wilson RS, Burns DK, Roses AD, Saunders AM, Gaiteri C, De Jager PL, Barnes LL, Bennett DA
Neurology 88 (7):661-668. PubMed PMID: 28108637
Published date: 2017 Feb 14
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (7):727-738. PubMed PMID: 28183528
Published date: 2017 Feb 06
Walking Pace and the Risk of Cognitive Decline and Dementia in Elderly Populations: A Meta-analysis of Prospective Cohort Studies.
Quan M, Xun P, Chen C, Wen J, Wang Y, Wang R, Chen P, He K
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (2):266-270. PubMed PMID: 27927757
Published date: 2017 02
Genetic architecture of age-related cognitive decline in African Americans.
Raj T, Chibnik LB, McCabe C, Wong A, Replogle JM, Yu L, Gao S, Unverzagt FW, Stranger B, Murrell J, Barnes L, Hendrie HC, Foroud T, Krichevsky A, Bennett DA, Hall KS, Evans DA, De Jager PL
Neurology. Genetics 3 (1):e125. PubMed PMID: 28078323
Published date: 2017 Feb
Association of Neuropathological Markers in the Parietal Cortex With Antemortem Cognitive Function in Persons With Mild Cognitive Impairment and Alzheimer Disease.
Tremblay C, Franc?ois A, Delay C, Freland L, Vandal M, Bennett DA, Calon F
Journal of neuropathology and experimental neurology. PubMed PMID: 28158844
Published date: 2017 Jan 31
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease.
Kelly SC, He B, Perez SE, Ginsberg SD, Mufson EJ, Counts SE
Acta neuropathologica communications 5 (1):8. PubMed PMID: 28109312
Published date: 2017 Jan 21
Baseline Characteristics of Participants in the ASPREE (ASPirin in Reducing Events in the Elderly) Study.
McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe RS, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG, Beilin LJ, Donnan GA, Gibb
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (11):1586-1593. PubMed PMID: 28329340
Published date: 2017 Jan 20
Novel genetic loci associated with hippocampal volume.
Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivie?res S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Be
Nature communications. PubMed PMID: 28098162
Published date: 2017 Jan 18
TDP-43 pathology and memory impairment in elders without pathologic diagnoses of AD or FTLD.
Nag S, Yu L, Wilson RS, Chen EY, Bennett DA, Schneider JA
Neurology 88 (7):653-660. PubMed PMID: 28087828
Published date: 2017 Jan 13
Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline.
Boyle PA, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Wilson RS, Bennett DA
Brain : a journal of neurology 140 (3):804-812. PubMed PMID: 28082297
Published date: 2017 Jan 12
The complex genetics of gait speed: genome-wide meta-analysis approach.
Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JA, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, P
Aging 9 (1):209-246. PubMed PMID: 28077804
Published date: 2017 Jan 10
A genome-wide profiling of brain DNA hydroxymethylation in Alzheimer's disease.
Zhao J, Zhu Y, Yang J, Li L, Wu H, De Jager PL, Jin P, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):674-688. PubMed PMID: 28089213
Published date: 2017 Jan 06
Perceived Stress and Cognitive Decline in Different Cognitive Domains in a Cohort of Older African Americans.
Turner AD, James BD, Capuano AW, Aggarwal NT, Barnes LL
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 25 (1):25-34. PubMed PMID: 28231871
Published date: 2017 Jan
Biomarkers for the Early Detection and Progression of Alzheimer's Disease.
Counts SE, Ikonomovic MD, Mercado N, Vega IE, Mufson EJ
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 14 (1):35-53. PubMed PMID: 27738903
Published date: 2017 Jan
Association of Cancer History with Alzheimer's Disease Dementia and Neuropathology.
Yarchoan M, James BD, Shah RC, Arvanitakis Z, Wilson RS, Schneider J, Bennett DA, Arnold SE
Journal of Alzheimer's disease : JAD 56 (2):699-706. PubMed PMID: 28035936
Published date: 2016 Dec 30
Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease.
Dodge HH, Zhu J, Woltjer R, Nelson PT, Bennett DA, Cairns NJ, Fardo DW, Kaye JA, Lyons DE, Mattek N, Schneider JA, Silbert LC, Xiong C, Yu L, Schmitt FA, Kryscio RJ, Abner EL
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):613-623. PubMed PMID: 28017827
Published date: 2016 Dec 23
Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions.
Hill WD, Davies G, Harris SE, Hagenaars SP, Liewald DC, Penke L, Gale CR, Deary IJ
Translational psychiatry 6 (12):e980. PubMed PMID: 27959336
Published date: 2016 Dec 13
A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression.
Carrasquillo MM, Allen M, Burgess JD, Wang X, Strickland SL, Aryal S, Siuda J, Kachadoorian ML, Medway C, Younkin CS, Nair A, Wang C, Chanana P, Serie D, Nguyen T, Lincoln S, Malphrus KG, Morgan K, Golde TE, Price ND, White CC, De Jager PL, Bennett DA, As
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):663-673. PubMed PMID: 27939925
Published date: 2016 Dec 08
An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DH, Boomsma D, Breen G, Buttensch?n HN, Byrne EM, B?rglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E,
Biological psychiatry 82 (5):322-329. PubMed PMID: 28049566
Published date: 2016 Dec 08
Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.
Foveau B, Albrecht S, Bennett DA, Correa JA, LeBlanc AC
Acta neuropathologica communications 4 (1):127. PubMed PMID: 27931265
Published date: 2016 Dec 08
Urinary Incontinence, Incident Parkinsonism, and Parkinson's Disease Pathology in Older Adults.
Buchman NM, Leurgans SE, Shah RJ, VanderHorst V, Wilson RS, Bachner YG, Tanne D, Schneider JA, Bennett DA, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 72 (9):1295-1301. PubMed PMID: 27927762
Published date: 2016 Dec 07
Novel genetic loci underlying human intracranial volume identified through genome-wide association.
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Renteri?a ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivie?res S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Arms
Nature neuroscience 19 (12):1569-1582. PubMed PMID: 27694991
Published date: 2016 Dec
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.
Bordi M, Berg MJ, Mohan PS, Peterhoff CM, Alldred MJ, Che S, Ginsberg SD, Nixon RA
Autophagy 12 (12):2467-2483. PubMed PMID: 27813694
Published date: 2016 12
Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linne?r RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonza
Nature genetics 48 (12):1591. PubMed PMID: 27898078
Published date: 2016 Nov 29
Genome-Wide Association Analysis of the Sense of Smell in U.S. Older Adults: Identification of Novel Risk Loci in African-Americans and European-Americans.
Dong J, Wyss A, Yang J, Price TR, Nicolas A, Nalls M, Tranah G, Franceschini N, Xu Z, Schulte C, Alonso A, Cummings SR, Fornage M, Zaykin D, Li L, Huang X, Kritchevsky S, Liu Y, Gasser T, Wilson RS, De Jager PL, Singleton AB, Pinto JM, Harris T, Mosley TH
Molecular neurobiology 54 (10):8021-8032. PubMed PMID: 27878761
Published date: 2016 Nov 23
Genetic variants linked to education predict longevity.
Marioni RE, Ritchie SJ, Joshi PK, Hagenaars SP, Okbay A, Fischer K, Adams MJ, Hill WD, Davies G, Nagy R, Amador C, La?ll K, Metspalu A, Liewald DC, Campbell A, Wilson JF, Hayward C, Esko T, Porteous DJ, Gale CR, Deary IJ
Proceedings of the National Academy of Sciences of the United States of America 113 (47):13366-13371. PubMed PMID: 27799538
Published date: 2016 Nov 22
Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1.
Cronin P, McCarthy MJ, Lim AS, Salmon DP, Galasko D, Masliah E, De Jager PL, Bennett DA, Desplats P
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (6):689-700. PubMed PMID: 27883893
Published date: 2016 Nov 21
Addendum: REST and stress resistance in ageing and Alzheimer's disease.
T L, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaia?covo MP, Yankner BA
Nature 540 (7633):470. PubMed PMID: 27851730
Published date: 2016 Nov 16
Deletion of Neurotrophin Signaling through the Glucocorticoid Receptor Pathway Causes Tau Neuropathology.
Arango-Lievano M, Peguet C, Catteau M, Parmentier ML, Wu S, Chao MV, Ginsberg SD, Jeanneteau F
Scientific reports. PubMed PMID: 27849045
Published date: 2016 11 16
Willingness to Be a Brain Donor: A Survey of Research Volunteers From 4 Racial/Ethnic Groups.
Boise L, Hinton L, Rosen HJ, Ruhl MC, Dodge H, Mattek N, Albert M, Denny A, Grill JD, Hughes T, Lingler JH, Morhardt D, Parfitt F, Peterson-Hazan S, Pop V, Rose T, Shah RC
Alzheimer disease and associated disorders 31 (2):135-140. PubMed PMID: 27779492
Published date: 2016 Oct 24
Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans.
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ, Haines JL
Alzheimer's & dementia : the journal of the Alzheimer's Association 13 (2):119-129. PubMed PMID: 27770636
Published date: 2016 Oct 20
The characteristics of astrocyte on Aβ clearance altered in Alzheimer's disease were reversed by anti-inflammatory agent (+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate.
Liu RX, Huang C, Bennett DA, Li H, Wang R
American journal of translational research 8 (10):4082-4094. PubMed PMID: 27829994
Published date: 2016
White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age.
Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA
Annals of clinical and translational neurology 3 (10):791-800. PubMed PMID: 27752514
Published date: 2016 Oct
TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia.
James BD, Wilson RS, Boyle PA, Trojanowski JQ, Bennett DA, Schneider JA
Brain : a journal of neurology 139 (11):2983-2993. PubMed PMID: 27694152
Published date: 2016 Sep 30
Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer's Model.
Do Carmo S, Hanzel CE, Jacobs ML, Machnes Z, Iulita MF, Yang J, Yu L, Ducatenzeiler A, Danik M, Breuillaud LS, Bennett DA, Szyf M, Cuello AC
Scientific reports. PubMed PMID: 27681803
Published date: 2016
Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gu?mu?s? ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF,
Nature neuroscience 19 (11):1442-1453. PubMed PMID: 27668389
Published date: 2016 Sep 26
Molecular and cellular pathophysiology of preclinical Alzheimer's disease.
Mufson EJ, Ikonomovic MD, Counts SE, Perez SE, Malek-Ahmadi M, Scheff SW, Ginsberg SD
Behavioural brain research. PubMed PMID: 27185734
Published date: 2016 Sep 15
Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
Sherman MA, LaCroix M, Amar F, Larson ME, Forster C, Aguzzi A, Bennett DA, Ramsden M, Lesne? SE
The Journal of neuroscience : the official journal of the Society for Neuroscience 36 (37):9647-58. PubMed PMID: 27629715
Published date: 2016 Sep 14
Tenascin-C Is Associated with Cored Amyloid-β Plaques in Alzheimer Disease and Pathology Burdened Cognitively Normal Elderly.
Mi Z, Halfter W, Abrahamson EE, Klunk WE, Mathis CA, Mufson EJ, Ikonomovic MD
Journal of neuropathology and experimental neurology 75 (9):868-76. PubMed PMID: 27444354
Published date: 2016 Sep
The epigenome in Alzheimer's disease: current state and approaches for a new path to gene discovery and understanding disease mechanism.
Klein HU, Bennett DA, De Jager PL
Acta neuropathologica 132 (4):503-14. PubMed PMID: 27573688
Published date: 2016 Aug 29
Personality Polygenes, Positive Affect, and Life Satisfaction.
Weiss A, Baselmans BM, Hofer E, Yang J, Okbay A, Lind PA, Miller MB, Nolte IM, Zhao W, Hagenaars SP, Hottenga JJ, Matteson LK, Snieder H, Faul JD, Hartman CA, Boyle PA, Tiemeier H, Mosing MA, Pattie A, Davies G, Liewald DC, Schmidt R, De Jager PL, Heath A
Twin research and human genetics : the official journal of the International Society for Twin Studies 19 (5):1-11. PubMed PMID: 27546527
Published date: 2016 Aug 22
The Role of Cardiovascular Risk Factors and Stroke in Familial Alzheimer Disease.
Tosto G, Bird TD, Bennett DA, Boeve BF, Brickman AM, Cruchaga C, Faber K, Foroud TM, Farlow M, Goate AM, Graff-Radford NR, Lantigua R, Manly J, Ottman R, Rosenberg R, Schaid DJ, Schupf N, Stern Y, Sweet RA, Mayeux R
JAMA neurology 73 (10):1231-1237. PubMed PMID: 27533593
Published date: 2016 Aug 15
An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease.
Horvath S, Gurven M, Levine ME, Trumble BC, Kaplan H, Allayee H, Ritz BR, Chen B, Lu AT, Rickabaugh TM, Jamieson BD, Sun D, Li S, Chen W, Quintana-Murci L, Fagny M, Kobor MS, Tsao PS, Reiner AP, Edlefsen KL, Absher D, Assimes TL
Genome biology 17 (1):171. PubMed PMID: 27511193
Published date: 2016 08 11
Incident parkinsonism in older adults without Parkinson disease.
Buchman AS, Leurgans SE, Yu L, Wilson RS, Lim AS, James BD, Shulman JM, Bennett DA
Neurology 87 (10):1036-44. PubMed PMID: 27488597
Published date: 2016 Aug 3
Reduced pCREB in Alzheimer's disease prefrontal cortex is reflected in peripheral blood mononuclear cells.
Bartolotti N, Bennett DA, Lazarov O
Molecular psychiatry 21 (9):1158-66. PubMed PMID: 27480489
Published date: 2016 Aug 2
Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, De Jager PL, Bradshaw EM
Neurology. Genetics 2 (4):e90. PubMed PMID: 27504496
Published date: 2016 Aug
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults.
Valenca GT, Srivastava GP, Oliveira-Filho J, White CC, Yu L, Schneider JA, Buchman AS, Shulman JM, Bennett DA, De Jager PL
PloS one 11 (7):e0157452. PubMed PMID: 27458716
Published date: 2016
Neuritic and Diffuse Plaque Associations with Memory in Non-Cognitively Impaired Elderly.
Malek-Ahmadi M, Perez SE, Chen K, Mufson EJ
Journal of Alzheimer's disease : JAD 53 (4):1641-52. PubMed PMID: 27540968
Published date: 2016 Jul 14
Association of Traumatic Brain Injury With Late-Life Neurodegenerative Conditions and Neuropathologic Findings.
Crane PK, Gibbons LE, Dams-O'Connor K, Trittschuh E, Leverenz JB, Keene CD, Sonnen J, Montine TJ, Bennett DA, Leurgans S, Schneider JA, Larson EB
JAMA neurology 73 (9):1062-9. PubMed PMID: 27400367
Published date: 2016 Jul 11
Braak stage and trajectory of cognitive decline in noncognitively impaired elders.
Mufson EJ, Malek-Ahmadi M, Snyder N, Ausdemore J, Chen K, Perez SE
Neurobiology of aging. PubMed PMID: 27255819
Published date: 2016 Jul
A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers.
Jack CR, Bennett DA, Blennow K, Carrillo MC, Feldman HH, Frisoni GB, Hampel H, Jagust WJ, Johnson KA, Knopman DS, Petersen RC, Scheltens P, Sperling RA, Dubois B
Neurology 87 (5):539-47. PubMed PMID: 27371494
Published date: 2016 Jul 1
Relation of genomic variants for Alzheimer disease dementia to common neuropathologies.
Farfel JM, Yu L, Buchman AS, Schneider JA, De Jager PL, Bennett DA
Neurology 87 (5):489-96. PubMed PMID: 27371493
Published date: 2016 Jul 1
GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium.
Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Ev
Aging cell 15 (5):792-800. PubMed PMID: 27325353
Published date: 2016 Jun 21
Evaluation of a Genetic Risk Score to Improve Risk Prediction for Alzheimer's Disease.
Chouraki V, Reitz C, Maury F, Bis JC, Bellenguez C, Yu L, Jakobsdottir J, Mukherjee S, Adams HH, Choi SH, Larson EB, Fitzpatrick A, Uitterlinden AG, de Jager PL, Hofman A, Gudnason V, Vardarajan B, Ibrahim-Verbaas C, van der Lee SJ, Lopez O, Dartigues JF,
Journal of Alzheimer's disease : JAD 53 (3):921-32. PubMed PMID: 27340842
Published date: 2016 Jun 18
Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study.
Arvanitakis Z, Capuano AW, Leurgans SE, Bennett DA, Schneider JA
The Lancet. Neurology 15 (9):934-43. PubMed PMID: 27312738
Published date: 2016 Jun 13
Genetic variants in Alzheimer disease - molecular and brain network approaches.
Gaiteri C, Mostafavi S, Honey CJ, De Jager PL, Bennett DA
Nature reviews. Neurology 12 (7):413-27. PubMed PMID: 27282653
Published date: 2016 Jun 10
Postmortem MRI: a novel window into the neurobiology of late life cognitive decline.
Dawe RJ, Yu L, Leurgans SE, Schneider JA, Buchman AS, Arfanakis K, Bennett DA, Boyle PA
Neurobiology of aging. PubMed PMID: 27459937
Published date: 2016 Jun 6
NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.
Ali YO, Allen HM, Yu L, Li-Kroeger D, Bakhshizadehmahmoudi D, Hatcher A, McCabe C, Xu J, Bjorklund N, Taglialatela G, Bennett DA, De Jager PL, Shulman JM, Bellen HJ, Lu HC
PLoS biology 14 (6):e1002472. PubMed PMID: 27254664
Published date: 2016 Jun
Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease.
Tiernan CT, Ginsberg SD, Guillozet-Bongaarts AL, Ward SM, He B, Kanaan NM, Mufson EJ, Binder LI, Counts SE
Neurobiology of aging. PubMed PMID: 27143424
Published date: 2016 Jun
Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology.
Scheff SW, Ansari MA, Mufson EJ
Neurobiology of aging. PubMed PMID: 27143416
Published date: 2016 Jun
Genome-wide association study identifies 74 loci associated with educational attainment.
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Con
Nature 533 (7604):539-42. PubMed PMID: 27225129
Published date: 2016 May 26
Measurement and control of bias in patient reported outcomes using multidimensional item response theory.
Dowling NM, Bolt DM, Deng S, Li C
BMC medical research methodology. PubMed PMID: 27229310
Published date: 2016 05 26
Late-life Cognitive Activity and Dementia: A Systematic Review and Bias Analysis.
Sajeev G, Weuve J, Jackson JW, VanderWeele TJ, Bennett DA, Grodstein F, Blacker D
Epidemiology (Cambridge, Mass.) 27 (5):732-42. PubMed PMID: 27227783
Published date: 2016 May 25
Assessment of the genetic variance of late-onset Alzheimer's disease.
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JSK
Neurobiology of aging. PubMed PMID: 27036079
Published date: 2016 May
Motor Function Is Associated With Incident Disability in Older African Americans.
Buchman AS, Wilson RS, Yu L, Boyle PA, Bennett DA, Barnes LL
The journals of gerontology. Series A, Biological sciences and medical sciences 71 (5):696-702. PubMed PMID: 26525087
Published date: 2016 May
The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable.
Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK
Neurobiology of aging. PubMed PMID: 27103524
Published date: 2016 May
Sigmoidal mixed models for longitudinal data.
Capuano AW, Wilson RS, Leurgans SE, Dawson JD, Bennett DA, Hedeker D
Statistical methods in medical research 27 (3):863-875. PubMed PMID: 27130491
Published date: 2016 Apr 28
Temporal course of neurodegenerative effects on cognition in old age.
Wilson RS, Capuano AW, Bennett DA, Schneider JA, Boyle PA
Neuropsychology 30 (5):591-9. PubMed PMID: 27111293
Published date: 2016 Apr 25
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.
Okbay A, Baselmans BM, De Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linne?r RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonza
Nature genetics 48 (6):624-33. PubMed PMID: 27089181
Published date: 2016 Apr 18
Occupational cognitive requirements and late-life cognitive aging.
Pool LR, Weuve J, Wilson RS, Bültmann U, Evans DA, Mendes de Leon CF
Neurology 86 (15):1386-1392. PubMed PMID: 26984944
Published date: 2016 04 12
Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.
Allen GI, Amoroso N, Anghel C, Balagurusamy V, Bare CJ, Beaton D, Bellotti R, Bennett DA, Boehme K, Boutros PC, Caberlotto L, Caloian C, Campbell F, Neto EC, Chang YC, Chen B, Chen CY, Chien TY, Clark T, Das S, Davatzikos C, Deng J, Dillenberger D, Dobson
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (6):645-53. PubMed PMID: 27079753
Published date: 2016 Apr 11
Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant.
Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 36 (4):819-30. PubMed PMID: 26762507
Published date: 2016 Apr
Genome-wide interaction study of brain beta-amyloid burden and cognitive impairment in Alzheimer's disease.
Roostaei T, Nazeri A, Felsky D, De Jager PL, Schneider JA, Pollock BG, Bennett DA, Voineskos AN
Molecular psychiatry 22 (2):287-295. PubMed PMID: 27021820
Published date: 2016 Mar 29
Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology.
Yu L, Chibnik L, Yang J, McCabe C, Xu J, Schneider JA, De Jager PL, Bennett DA
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (9):942-51. PubMed PMID: 27016692
Published date: 2016 Mar 23
Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies.
Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, Wellmann J, Cornelis MC, Ollila HM, Yu L, Smith JA, Pilling LC, Isaacs A, Palotie A, Zhuang WV, Zonderman A, Faul JD, Sutin A, Meirelles O, Mulas A,
Psychological medicine 46 (8):1-11. PubMed PMID: 26997408
Published date: 2016 Mar 21
Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk.
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T,
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (3):233-43. PubMed PMID: 26092349
Published date: 2016 Mar
Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
Karch CM, Ezerskiy LA, Bertelsen S, Goate AM
PloS one 11 (2):e0148717. PubMed PMID: 26919393
Published date: 2016
Independent and interactive impacts of hypertension and diabetes mellitus on verbal memory: A coordinated analysis of longitudinal data from England, Sweden, and the United States.
Kelly A, Calamia M, Koval A, Terrera GM, Piccinin AM, Clouston S, Hassing LB, Bennett DA, Johansson B, Hofer SM
Psychology and aging 31 (3):262-73. PubMed PMID: 26913926
Published date: 2016 Feb 25
Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides.
Hinrich AJ, Jodelka FM, Chang JL, Brutman D, Bruno AM, Briggs CA, James BD, Stutzmann GE, Bennett DA, Miller SA, Rigo F, Marr RA, Hastings ML
EMBO molecular medicine 8 (4):328-45. PubMed PMID: 26902204
Published date: 2016 Feb 22
Assessing the genetic overlap between BMI and cognitive function.
Marioni RE, Yang J, Dykiert D, Mo?ttus R, Campbell A, Davies G, Hayward C, Porteous DJ, Visscher PM, Deary IJ
Molecular psychiatry 21 (10):1477-82. PubMed PMID: 26857597
Published date: 2016 Feb 9
The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts.
Arvanitakis Z, Capuano AW, Leurgans SE, Buchman AS, Bennett DA, Schneider JA
Brain pathology (Zurich, Switzerland) 27 (1):77-85. PubMed PMID: 26844934
Published date: 2016 Feb 4
Interaction between variants in CLU and MS4A4E modulates Alzheimer's disease risk.
Ebbert MTW, Boehme KL, Wadsworth ME, Staley LA, Mukherjee S, Crane PK, Ridge PG, Kauwe JSK
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (2):121-129. PubMed PMID: 26449541
Published date: 2016 Feb
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Lu Y, Day FR, Gustafsson S, Buchkovich ML, Na J, Bataille V, Cousminer DL, Dastani Z, Drong AW, Esko T, Evans DM, Falchi M, Feitosa MF, Ferreira T, Hedman A?K, Haring R, Hysi PG, Iles MM, Justice AE, Kanoni S, Lagou V, Li R, Li X, Locke A, Lu C, Ma?gi R
Nature communications. PubMed PMID: 26833246
Published date: 2016 Feb 01
Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium.
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, Haines JL, Thornton-Wells TA
Neurobiology of aging. PubMed PMID: 26827652
Published date: 2016 Feb
Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease.
Counts SE, He B, Prout JG, Michalski B, Farotti L, Fahnestock M, Mufson EJ
Current Alzheimer research 13 (7):800-8. PubMed PMID: 26825093
Published date: 2016
Higher brain BDNF gene expression is associated with slower cognitive decline in older adults.
Buchman AS, Yu L, Boyle PA, Schneider JA, De Jager PL, Bennett DA
Neurology 86 (8):735-41. PubMed PMID: 26819457
Published date: 2016 Jan 27
Olfactory Dysfunction in Older Adults is Associated with Feelings of Depression and Loneliness.
Sivam A, Wroblewski KE, Alkorta-Aranburu G, Barnes LL, Wilson RS, Bennett DA, Pinto JM
Chemical senses 41 (4):293-9. PubMed PMID: 26809485
Published date: 2016 Jan 24
Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.
Abner EL, Nelson PT, Kryscio RJ, Schmitt FA, Fardo DW, Woltjer RL, Cairns NJ, Yu L, Dodge HH, Xiong C, Masaki K, Tyas SL, Bennett DA, Schneider JA, Arvanitakis Z
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (8):882-9. PubMed PMID: 26812281
Published date: 2016 Jan 23
Cardiorespiratory fitness and cognition in the elderly: Can you outrun cognitive impairment?
Roever L, Bennett DA
Neurology 86 (5):408-9. PubMed PMID: 26740672
Published date: 2016 Jan 6
Evidence for Mitochondrial UPR Gene Activation in Familial and Sporadic Alzheimer's Disease.
Beck JS, Mufson EJ, Counts SE
Current Alzheimer research 13 (6):610-4. PubMed PMID: 26687188
Published date: 2016
Braak staging, plaque pathology, and APOE status in elderly persons without cognitive impairment.
Mufson EJ, Malek-Ahmadi M, Perez SE, Chen K
Neurobiology of aging. PubMed PMID: 26686670
Published date: 2016 Jan
Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer's disease related cognitive functioning.
Levine ME, Lu AT, Bennett DA, Horvath S
Aging 7 (12):1198-211. PubMed PMID: 26684672
Published date: 2015 Dec 18
Identifying the Association Between Alzheimer's Disease and Parkinson's Disease Using Genome-Wide Association Studies and Protein-Protein Interaction Network.
Liu G, Bao X, Jiang Y, Liao M, Jiang Q, Feng R, Zhang L, Ma G, Chen Z, Wang G, Wang R, Zhao B, Li K
Molecular neurobiology 52 (3):1629-1636. PubMed PMID: 25370933
Published date: 2015 Dec
Hippocampal plasticity during the progression of Alzheimer's disease.
Mufson EJ, Mahady L, Waters D, Counts SE, Perez SE, DeKosky ST, Ginsberg SD, Ikonomovic MD, Scheff SW, Binder LI
Neuroscience. PubMed PMID: 25772787
Published date: 2015 Nov 19
Antihypertensive and Statin Medication Use and Motor Function in Community-Dwelling Older Adults.
Perlman A, Shah RC, Bennett DA, Buchman AS, Matok I
Journal of the American Medical Directors Association 17 (3):220-224. PubMed PMID: 26597419
Published date: 2015 Nov 17
Examination of the Factor Structure of a Global Cognitive Function Battery across Race and Time.
Barnes LL, Yumoto F, Capuano A, Wilson RS, Bennett DA, Tractenberg RE
Journal of the International Neuropsychological Society : JINS 22 (1):1-10. PubMed PMID: 26563713
Published date: 2015 Nov 13
Change in Cognitive Abilities in Older Latinos.
Wilson RS, Capuano AW, Marquez DX, Amofa P, Barnes LL, Bennett DA
Journal of the International Neuropsychological Society : JINS 22 (1):1-8. PubMed PMID: 26553103
Published date: 2015 Nov 10
Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment.
Weinberg RB, Mufson EJ, Counts SE
Frontiers in neuroscience. PubMed PMID: 26594146
Published date: 2015
Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons.
Boyle PA, Yu L, Nag S, Leurgans S, Wilson RS, Bennett DA, Schneider JA
Neurology 85 (22):1930-6. PubMed PMID: 26537052
Published date: 2015 Nov 4
Evidence for Alzheimer's disease-linked synapse loss and compensation in mouse and human hippocampal CA1 pyramidal neurons.
Neuman KM, Molina-Campos E, Musial TF, Price AL, Oh KJ, Wolke ML, Buss EW, Scheff SW, Mufson EJ, Nicholson DA
Brain structure & function 220 (6):3143-65. PubMed PMID: 25031178
Published date: 2015 Nov
Genome-wide Meta-analysis on the Sense of Smell Among US Older Adults.
Dong J, Yang J, Tranah G, Franceschini N, Parimi N, Alkorta-Aranburu G, Xu Z, Alonso A, Cummings SR, Fornage M, Huang X, Kritchevsky S, Liu Y, London S, Niu L, Wilson RS, De Jager PL, Yu L, Singleton AB, Harris T, Mosley TH, Pinto JM, Bennett DA, Chen H
Medicine 94 (47):e1892. PubMed PMID: 26632684
Published date: 2015 Nov
Author Response.
Schneider JA, Yu L, Bennett DA
Neurology 85 (15):1355. PubMed PMID: 26744756
Published date: 2015 Oct 13
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Dickson DW, Rademakers R, Nicholson AM, Schneider JA, Yu L, Bennett DA
Neurology 85 (15):1354-5. PubMed PMID: 26459943
Published date: 2015 Oct 13
Common variants in DRD2 are associated with sleep duration: the CARe consortium.
Cade BE, Gottlieb DJ, Lauderdale DS, Bennett DA, Buchman AS, Buxbaum SG, De Jager PL, Evans DS, Fu?lo?p T, Gharib SA, Johnson WC, Kim H, Larkin EK, Lee SK, Lim AS, Punjabi NM, Shin C, Stone KL, Tranah GJ, Weng J, Yaffe K, Zee PC, Patel SR, Zhu X, Red
Human molecular genetics 25 (1):167-79. PubMed PMID: 26464489
Published date: 2015 Oct 13
Parsing the heterogeneity of mild cognitive impairment: Lumpers and splitters.
Burns JM, Bennett DA
Neurology 85 (19):1646-7. PubMed PMID: 26453644
Published date: 2015 Oct 9
Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers.
Lugli G, Cohen AM, Bennett DA, Shah RC, Fields CJ, Hernandez AG, Smalheiser NR
PloS one 10 (10):e0139233. PubMed PMID: 26426747
Published date: 2015
Alzheimer's disease: Unique markers for diagnosis & new treatment modalities.
Aggarwal NT, Shah RC, Bennett DA
The Indian journal of medical research 142 (4):369-82. PubMed PMID: 26609028
Published date: 2015 Oct
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpela?inen TO, Lu Y, Ma?gi R, Mihailov E, Pers TH, Ru?eger S, Teumer A, Ehret GB, Ferreira T, Heard-Costa NL, Karjalainen J, Lagou V, Mahajan A, Neinast MD,
PLoS genetics 11 (10):e1005378. PubMed PMID: 26426971
Published date: 2015 Oct
Association of APOE with tau-tangle pathology with and without β-amyloid.
Farfel JM, Yu L, De Jager PL, Schneider JA, Bennett DA
Neurobiology of aging. PubMed PMID: 26481403
Published date: 2015 Sep 28
CD33 modulates TREM2: convergence of Alzheimer loci.
Chan G, White CC, Winn PA, Cimpean M, Replogle JM, Glick LR, Cuerdon NE, Ryan KJ, Johnson KA, Schneider JA, Bennett DA, Chibnik LB, Sperling RA, Bradshaw EM, De Jager PL
Nature neuroscience 18 (11):1556-8. PubMed PMID: 26414614
Published date: 2015 Sep 28
Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer's Disease and APPswe/PS1dE9 Double Transgenic Mice Brains.
Zhang J, Wang S, Huang W, Bennett DA, Dickson DW, Wang D, Wang R
Molecular neurobiology 53 (8):5066-78. PubMed PMID: 26386840
Published date: 2015 Sep 19
Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals.
Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC
JAMA neurology 72 (11):1313-23. PubMed PMID: 26366463
Published date: 2015 Sep 14
miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.
Smith PY, Hernandez-Rapp J, Jolivette F, Lecours C, Bisht K, Goupil C, Dorval V, Parsi S, Morin F, Planel E, Bennett DA, Fernandez-Gomez FJ, Sergeant N, Bue?e L, Tremblay ME?, Calon F, He?bert SS
Human molecular genetics 24 (23):6721-35. PubMed PMID: 26362250
Published date: 2015 Sep 11
Parkinsonism in Older Adults and Its Association With Adverse Health Outcomes and Neuropathology.
Buchman AS, Wilson RS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 71 (4):549-56. PubMed PMID: 26362440
Published date: 2015 Sep 10
Guidelines for reporting methodological challenges and evaluating potential bias in dementia research.
Weuve J, Proust-Lima C, Power MC, Gross AL, Hofer SM, Thibaut R, Chne G, Glymour MM, Dufouil C
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (9):1098-109. PubMed PMID: 26397878
Published date: 2015 Sep
Quantile regression with a change-point model for longitudinal data: An application to the study of cognitive changes in preclinical alzheimer's disease.
Li C, Dowling NM, Chappell R
Biometrics 71 (3):625-35. PubMed PMID: 25892034
Published date: 2015 Sep
Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease.
Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, Trojanowski JQ, Vinters HV, Zhou XH, Hyman BT
Alzheimer's & dementia : the journal of the Alzheimer's Association 12 (2):164-9. PubMed PMID: 26327235
Published date: 2015 Aug 29
Temporal course and pathologic basis of unawareness of memory loss in dementia.
Wilson RS, Boyle PA, Yu L, Barnes LL, Sytsma J, Buchman AS, Bennett DA, Schneider JA
Neurology 85 (11):984-91. PubMed PMID: 26311746
Published date: 2015 Aug 26
Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families.
Barral S, Vardarajan BN, Faber KM, Bird TD, Tsuang D, Bennett DA, Rosenberg R, Boeve BF, Graff-Radford NR, Goate AM, Farlow M, Lantigua R, Medrano MZ, Wang X, Kamboh MI, Barmada MM, Schaid DJ, Foroud TM, Weamer EA, Ottman R, Sweet RA, Mayeux R
Neurobiology of aging 36 (11):3116.e9-3116.e16. PubMed PMID: 26359528
Published date: 2015 Aug 15
APOE and cerebral amyloid angiopathy in community-dwelling older persons.
Yu L, Boyle PA, Nag S, Leurgans S, Buchman AS, Wilson RS, Arvanitakis Z, Farfel JM, De Jager PL, Bennett DA, Schneider JA
Neurobiology of aging 36 (11):2946-53. PubMed PMID: 26341746
Published date: 2015 Aug 15
GWAS of longitudinal amyloid accumulation on 18F-florbetapir PET in Alzheimer's disease implicates microglial activation gene IL1RAP.
Ramanan VK, Risacher SL, Nho K, Kim S, Shen L, McDonald BC, Yoder KK, Hutchins GD, West JD, Tallman EF, Gao S, Foroud TM, Farlow MR, De Jager PL, Bennett DA, Aisen PS, Petersen RC, Jack CR, Toga AW, Green RC, Jagust WJ, Weiner MW, Saykin AJ
Brain : a journal of neurology 138 (Pt 10):3076-3088. PubMed PMID: 26268530
Published date: 2015 Aug 11
Late-life depression is not associated with dementia-related pathology.
Wilson RS, Boyle PA, Capuano AW, Shah RC, Hoganson GM, Nag S, Bennett DA
Neuropsychology 30 (2):135-42. PubMed PMID: 26237627
Published date: 2015 Aug 3
Author response.
Verghese J, Kowal P, Bennett DA
Neurology 85 (4):389. PubMed PMID: 26436154
Published date: 2015 Jul 28
Motoric cognitive risk syndrome: multicenter incidence study.
Mahlknecht P, Kiechl S, Willeit J, Poewe W, Seppi K, Verghese J, Kowal P, Bennett DA
Neurology 85 (4):388-9. PubMed PMID: 26215881
Published date: 2015 Jul 28
Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease.
Rangasamy SB, Corbett GT, Roy A, Modi KK, Bennett DA, Mufson EJ, Ghosh S, Pahan K
Journal of Alzheimer's disease : JAD 47 (2):385-402. PubMed PMID: 26401561
Published date: 2015 Jul 24
GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.
Hohman TJ, Chibnik L, Bush WS, Jefferson AL, De Jaeger PL, Thornton-Wells TA, Bennett DA, Schneider JA
Neurotoxicity research 28 (3):232-8. PubMed PMID: 26194614
Published date: 2015 Jul 21
Change in motor function and adverse health outcomes in older African-Americans.
Buchman AS, Wilson RS, Leurgans SE, Bennett DA, Barnes LL
Experimental gerontology. PubMed PMID: 26209439
Published date: 2015 Jul 21
Mixed pathology is more likely in black than white decedents with Alzheimer dementia.
Barnes LL, Leurgans S, Aggarwal NT, Shah RC, Arvanitakis Z, James BD, Buchman AS, Bennett DA, Schneider JA
Neurology 85 (6):528-34. PubMed PMID: 26180136
Published date: 2015 Jul 15
Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.
Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV
Nature neuroscience 18 (7):978-87. PubMed PMID: 26005850
Published date: 2015 Jul
Neuropathologic correlates of regional brain volumes in a community cohort of older adults.
Kotrotsou A, Schneider JA, Bennett DA, Leurgans SE, Dawe RJ, Boyle PA, Golak T, Arfanakis K
Neurobiology of aging 36 (10):2798-805. PubMed PMID: 26195068
Published date: 2015 Jun 30
Reply to Itzhaki.
Barnes LL, Capuano AW, Aiello AE, Turner AD, Yolken RH, Torrey EF, Bennett DA
The Journal of infectious diseases 211 (12):2024. PubMed PMID: 25635124
Published date: 2015 Jun 15
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Mukherjee S, Walter S, Kauwe JS, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (12):1439-51. PubMed PMID: 26079416
Published date: 2015 Jun 12
Vascular contributions to cognitive impairment and dementia including Alzheimer's disease.
Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (6):710-7. PubMed PMID: 25510382
Published date: 2015 Jun
Alzheimer's loci: epigenetic associations and interaction with genetic factors.
Chibnik LB, Yu L, Eaton ML, Srivastava G, Schneider JA, Kellis M, Bennett DA, De Jager PL
Annals of clinical and translational neurology 2 (6):636-47. PubMed PMID: 26125039
Published date: 2015 Jun
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies.
Yang J, Yu L, Gaiteri C, Srivastava GP, Chibnik LB, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA
The international journal of biochemistry & cell biology. PubMed PMID: 26003740
Published date: 2015 May 20
Cognitive activity, cognitive function, and brain diffusion characteristics in old age.
Arfanakis K, Wilson RS, Barth CM, Capuano AW, Vasireddi A, Zhang S, Fleischman DA, Bennett DA
Brain imaging and behavior 10 (2):455-63. PubMed PMID: 25982658
Published date: 2015 May 16
Cognitive aging in older Black and White persons.
Wilson RS, Capuano AW, Sytsma J, Bennett DA, Barnes LL
Psychology and aging 30 (2):279-85. PubMed PMID: 25961876
Published date: 2015 May 11
PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.
Jellinger KA, Alafuzoff I, Attems J, Beach TG, Cairns NJ, Crary JF, Dickson DW, Hof PR, Hyman BT, Jack CR, Jicha GA, Knopman DS, Kovacs GG, Mackenzie IR, Masliah E, Montine TJ, Nelson PT, Schmitt F, Schneider JA, Serrano-Pozo A, Thal DR, Toledo JB, T
Acta neuropathologica 129 (5):757-62. PubMed PMID: 25778618
Published date: 2015 May
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J, Willems
Molecular psychiatry 20 (6):735-43. PubMed PMID: 25917368
Published date: 2015 Apr 28
Effect of common neuropathologies on progression of late life cognitive impairment.
Yu L, Boyle PA, Leurgans S, Schneider JA, Kryscio RJ, Wilson RS, Bennett DA
Neurobiology of aging 36 (7):2225-31. PubMed PMID: 25976345
Published date: 2015 Apr 22
α-Synuclein pathology accumulates in sacral spinal visceral sensory pathways.
VanderHorst VG, Samardzic T, Saper CB, Anderson MP, Nag S, Schneider JA, Bennett DA, Buchman AS
Annals of neurology 78 (1):142-9. PubMed PMID: 25893830
Published date: 2015 Apr 20
Resilience of precuneus neurotrophic signaling pathways despite amyloid pathology in prodromal Alzheimer's disease.
Perez SE, He B, Nadeem M, Wuu J, Scheff SW, Abrahamson EE, Ikonomovic MD, Mufson EJ
Biological psychiatry 77 (8):693-703. PubMed PMID: 24529280
Published date: 2015 Apr 15
GWAS for executive function and processing speed suggests involvement of the CADM2 gene.
Ibrahim-Verbaas CA, Bressler J, Debette S, Schuur M, Smith AV, Bis JC, Davies G, Trompet S, Smith JA, Wolf C, Chibnik LB, Liu Y, Vitart V, Kirin M, Petrovic K, Polasek O, Zgaga L, Fawns-Ritchie C, Hoffmann P, Karjalainen J, Lahti J, Llewellyn DJ, Sch
Molecular psychiatry 21 (2):189-97. PubMed PMID: 25869804
Published date: 2015 Apr 14
Dementia: Cognitive resilience in APOE*ε4 carriers—is race important?
Barnes LL, Bennett DA
Nature reviews. Neurology 11 (4):190-1. PubMed PMID: 25799927
Published date: 2015 Apr
Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology.
Perez SE, He B, Nadeem M, Wuu J, Ginsberg SD, Ikonomovic MD, Mufson EJ
Journal of neuropathology and experimental neurology 74 (4):345-58. PubMed PMID: 25756588
Published date: 2015 Apr
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
Chauhan G, Adams HH, Bis JC, Weinstein G, Yu L, To?glhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikan
Neurobiology of aging 36 (4):1765.e7-16. PubMed PMID: 25670335
Published date: 2015 Apr
The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia.
Abner EL, Schmitt FA, Nelson PT, Lou W, Wan L, Gauriglia R, Dodge HH, Woltjer RL, Yu L, Bennet DA, Schneider JA, Chen R, Masaki K, Katz MJ, Lipton RB, Dickson DW, Lim KO, Hemmy LS, Cairns NJ, Grant E, Tyas SL, Xiong C, Fardo DW, Kryscio RJ
Observational studies 1 (2015):56-73. PubMed PMID: 25984574
Published date: 2015 Mar
Conscientiousness, dementia related pathology, and trajectories of cognitive aging.
Wilson RS, Boyle PA, Yu L, Segawa E, Sytsma J, Bennett DA
Psychology and aging 30 (1):74-82. PubMed PMID: 25664558
Published date: 2015 Mar
From Neurodegeneration to Brain Health: An Integrated Approach.
Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz W, Wang Y, Whitehouse P, Lerner A
Journal of Alzheimer's disease : JAD 46 (1):271-83. PubMed PMID: 25720413
Published date: 2015 Feb 26
Hippocampal sclerosis and TDP-43 pathology in aging and Alzheimer disease.
Nag S, Yu L, Capuano AW, Wilson RS, Leurgans SE, Bennett DA, Schneider JA
Annals of neurology 77 (6):942-52. PubMed PMID: 25707479
Published date: 2015 Feb 23
Integrative analysis of 111 reference human epigenomes.
Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coar
Nature 518 (7539):317-30. PubMed PMID: 25693563
Published date: 2015 Feb 19
B-lymphocyte-mediated delayed cognitive impairment following stroke.
Doyle KP, Quach LN, Sole? M, Axtell RC, Nguyen TV, Soler-Llavina GJ, Jurado S, Han J, Steinman L, Longo FM, Schneider JA, Malenka RC, Buckwalter MS
The Journal of neuroscience : the official journal of the Society for Neuroscience 35 (5):2133-45. PubMed PMID: 25653369
Published date: 2015 Feb 04
The TMEM106B locus and TDP-43 pathology in older persons without FTLD.
Yu L, De Jager PL, Yang J, Trojanowski JQ, Bennett DA, Schneider JA
Neurology 84 (9):927-34. PubMed PMID: 25653292
Published date: 2015 Feb 4
Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53949).
Davies G, Armstrong N, Bis JC, Bressler J, Chouraki V, Giddaluru S, Hofer E, Ibrahim-Verbaas CA, Kirin M, Lahti J, van der Lee SJ, Le Hellard S, Liu T, Marioni RE, Oldmeadow C, Postmus I, Smith AV, Smith JA, Thalamuthu A, Thomson R, Vitart V, Wang J,
Molecular psychiatry 20 (2):183-92. PubMed PMID: 25644384
Published date: 2015 Feb 3
Synaptic change in the posterior cingulate gyrus in the progression of Alzheimer's disease.
Scheff SW, Price DA, Ansari MA, Roberts KN, Schmitt FA, Ikonomovic MD, Mufson EJ
Journal of Alzheimer's disease : JAD 43 (3):1073-90. PubMed PMID: 25147118
Published date: 2015
Cortical pyroglutamate amyloid-β levels and cognitive decline in Alzheimer's disease.
Pivtoraiko VN, Abrahamson EE, Leurgans SE, DeKosky ST, Mufson EJ, Ikonomovic MD
Neurobiology of aging 36 (1):12-9. PubMed PMID: 25048160
Published date: 2015 Jan
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA
The journals of gerontology. Series A, Biological sciences and medical sciences 70 (1):110-8. PubMed PMID: 25199915
Published date: 2015 Jan
Relationship between Auditory and Cognitive Abilities in Older Adults.
Sheft S, Shafiro V, Wang E, Barnes LL, Shah RC
PloS one 10 (8):e0134330. PubMed PMID: 26237423
Published date: 2015
Genetic diversity is a predictor of mortality in humans.
Bihlmeyer NA, Brody JA, Smith A, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza S, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M,
BMC genetics 15 (1):1274. PubMed PMID: 25543667
Published date: 2014 Dec 29
A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology.
Replogle JM, Chan G, White CC, Raj T, Winn PA, Evans DA, Sperling RA, Chibnik LB, Bradshaw EM, Schneider JA, Bennett DA, De Jager PL
Annals of neurology 77 (3):469-77. PubMed PMID: 25545807
Published date: 2014 Dec 26
Residual decline in cognition after adjustment for common neuropathologic conditions.
Yu L, Boyle PA, Segawa E, Leurgans S, Schneider JA, Wilson RS, Bennett DA
Neuropsychology 29 (3):335-43. PubMed PMID: 25495832
Published date: 2014 Dec 15
Motoric cognitive risk syndrome: Multicenter incidence study.
Verghese J, Ayers E, Barzilai N, Bennett DA, Buchman AS, Holtzer R, Katz MJ, Lipton RB, Wang C
Neurology 83 (24):2278-84. PubMed PMID: 25361778
Published date: 2014 Dec 09
Primary age-related tauopathy (PART): a common pathology associated with human aging.
Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, Hyman BT, Jellinger K, Jicha GA, Kovacs GG, Knopman DS, Kofler J, Kukull WA
Acta neuropathologica 128 (6):755-66. PubMed PMID: 25348064
Published date: 2014 Dec
Brain pathology contributes to simultaneous change in physical frailty and cognition in old age.
Buchman AS, Yu L, Wilson RS, Boyle PA, Schneider JA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 69 (12):1536-44. PubMed PMID: 25136002
Published date: 2014 Dec
Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium.
Debette S, Ibrahim Verbaas CA, Bressler J, Schuur M, Smith A, Bis JC, Davies G, Wolf C, Gudnason V, Chibnik LB, Yang Q, deStefano AL, de Quervain DJ, Srikanth V, Lahti J, Grabe HJ, Smith JA, Priebe L, Yu L, Karbalai N, Hayward C, Wilson JF, Campbell
Biological psychiatry 77 (8):749-63. PubMed PMID: 25648963
Published date: 2014 Nov 25
Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets.
Gross AL, Sherva R, Mukherjee S, Newhouse S, Kauwe JS, Munsie LM, Waterston LB, Bennett DA, Jones RN, Green RC, Crane PK
Neuroepidemiology 43 (3-4):194-205. PubMed PMID: 25402421
Published date: 2014 Nov 13
FASTKD2 is associated with memory and hippocampal structure in older adults.
Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Aisen PS, Petersen RC, Jack CR, Shaw LM, Trojanowski JQ, Weiner MW, Green RC, Toga AW, De
Molecular psychiatry 20 (10):1197-204. PubMed PMID: 25385369
Published date: 2014 Nov 11
Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease.
Yu L, Chibnik LB, Srivastava GP, Pochet N, Yang J, Xu J, Kozubek J, Obholzer N, Leurgans SE, Schneider JA, Meissner A, De Jager PL, Bennett DA
JAMA neurology 72 (1):15-24. PubMed PMID: 25365775
Published date: 2014 Nov 3
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex.
Lim AS, Srivastava GP, Yu L, Chibnik LB, Xu J, Buchman AS, Schneider JA, Myers AJ, Bennett DA, De Jager PL
PLoS genetics 10 (11):e1004792. PubMed PMID: 25375876
Published date: 2014 Nov
Relation of antiphospholipid antibodies to postmortem brain infarcts in older people.
Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Capuano AW, Yu L, Leurgans SE, Bennett DA, Levine SR
Circulation 131 (2):182-9. PubMed PMID: 25301832
Published date: 2014 Oct 9
Theoretical impact of Florbetapir (18F) amyloid imaging on diagnosis of alzheimer dementia and detection of preclinical cortical amyloid.
Beach TG, Schneider JA, Sue LI, Serrano G, Dugger BN, Monsell SE, Kukull W
Journal of neuropathology and experimental neurology 73 (10):948-53. PubMed PMID: 25192053
Published date: 2014 Oct
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer
JAMA neurology 71 (11):1394-404. PubMed PMID: 25199842
Published date: 2014 Sep 8
PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation.
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA
Annals of neurology 76 (3):379-92. PubMed PMID: 25043464
Published date: 2014 Sep
Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P
PLoS genetics 10 (9):e1004606. PubMed PMID: 25188341
Published date: 2014 Sep
Two rare AKAP9 variants are associated with Alzheimer's disease in African Americans.
Logue MW, Schu M, Vardarajan BN, Farrell J, Bennett DA, Buxbaum JD, Byrd GS, Ertekin-Taner N, Evans D, Foroud T, Goate A, Graff-Radford NR, Kamboh MI, Kukull WA, Manly JJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (6):609-618.e11. PubMed PMID: 25172201
Published date: 2014 Aug 26
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, Joachim C, Powell J, Lovestone S, Bennett DA, Schalkwyk LC, Mill J
Nature neuroscience 17 (9):1164-70. PubMed PMID: 25129077
Published date: 2014 Aug 17
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissn
Nature neuroscience 17 (9):1156-63. PubMed PMID: 25129075
Published date: 2014 Aug 17
Cytomegalovirus infection and risk of Alzheimer disease in older black and white individuals.
Barnes LL, Capuano AW, Aiello AE, Turner AD, Yolken RH, Torrey EF, Bennett DA
The Journal of infectious diseases 211 (2):230-7. PubMed PMID: 25108028
Published date: 2014 Aug 8
Parahippocampal white matter volume predicts Alzheimer's disease risk in cognitively normal old adults.
Stoub TR, Detoledo-Morrell L, Dickerson BC
Neurobiology of aging 35 (8):1855-61. PubMed PMID: 24656833
Published date: 2014 Aug
Clinical-pathologic study of depressive symptoms and cognitive decline in old age.
Wilson RS, Capuano AW, Boyle PA, Hoganson GM, Hizel LP, Shah RC, Nag S, Schneider JA, Arnold SE, Bennett DA
Neurology 83 (8):702-9. PubMed PMID: 25080520
Published date: 2014 Jul 30
Motoric cognitive risk syndrome: multicountry prevalence and dementia risk.
Verghese J, Annweiler C, Ayers E, Barzilai N, Beauchet O, Bennett DA, Bridenbaugh SA, Buchman AS, Callisaya ML, Camicioli R, Capistrant B, Chatterji S, De Cock AM, Ferrucci L, Giladi N, Guralnik JM, Hausdorff JM, Holtzer R, Kim KW, Kowal P, Kressig R
Neurology 83 (8):718-26. PubMed PMID: 25031288
Published date: 2014 Jul 16
At the interface of sensory and motor dysfunctions and Alzheimer's disease.
Albers MW, Gilmore GC, Kaye J, Murphy C, Wingfield A, Bennett DA, Boxer AL, Buchman AS, Cruickshanks KJ, Devanand DP, Duffy CJ, Gall CM, Gates GA, Granholm AC, Hensch T, Holtzer R, Hyman BT, Lin FR, McKee AC, Morris JC, Petersen RC, Silbert LC, Strub
Alzheimer's & dementia : the journal of the Alzheimer's Association 11 (1):70-98. PubMed PMID: 25022540
Published date: 2014 Jul 8
Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions.
Serrano GE, Sabbagh MN, Sue LI, Hidalgo JA, Schneider JA, Bedell BJ, Van Deerlin VM, Suh E, Akiyama H, Joshi AD, Pontecorvo MJ, Mintun MA, Beach TG
Journal of Alzheimer's disease : JAD 42 (3):813-21. PubMed PMID: 24927705
Published date: 2014 Jun 13
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, D
PloS one 9 (6):e94661. PubMed PMID: 24922517
Published date: 2014
Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise? - authors' reply.
Greenberg SM, Al-Shahi Salman R, Biessels GJ, van Buchem M, Cordonnier C, Lee JM, Montaner J, Schneider JA, Smith EE, Vernooij M, Werring DJ
The Lancet. Neurology 13 (6):540. PubMed PMID: 24849857
Published date: 2014 Jun
Missense variant in TREML2 protects against Alzheimer's disease.
Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, Bellenguez C, Brown K, Medway C, Haddick PC, van der Brug MP, Bhangale T, Ortmann W, Behrens T, Mayeux
Neurobiology of aging 35 (6):1510.e19-26. PubMed PMID: 24439484
Published date: 2014 Jun
Epigenomics of Alzheimer's disease.
Bennett DA, Yu L, Yang J, Srivastava GP, Aubin C, De Jager PL
Translational research : the journal of laboratory and clinical medicine 165 (1):200-220. PubMed PMID: 24905038
Published date: 2014 May 16
Life extension factor klotho enhances cognition.
Dubal DB, Yokoyama JS, Zhu L, Broestl L, Worden K, Wang D, Sturm VE, Kim D, Klein E, Yu GQ, Ho K, Eilertson KE, Yu L, Kuro-O M, De Jager PL, Coppola G, Small GW, Bennett DA, Kramer JH, Abraham CR, Miller BL, Mucke L
Cell reports 7 (4):1065-76. PubMed PMID: 24813892
Published date: 2014 May 7
Fragile X gene expansions are not associated with dementia.
Hall DA, Bennett DA, Filley CM, Shah RC, Kluger B, Ouyang B, Berry-Kravis E
Neurobiology of aging 35 (11):2637-2638. PubMed PMID: 24958193
Published date: 2014 May 2
A novel GRN mutation (GRN c.708+6_+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: clinicopathologic report of 6 cases.
Bit-Ivan EN, Suh E, Shim HS, Weintraub S, Hyman BT, Arnold SE, McCarty-Wood E, Van Deerlin VM, Schneider JA, Trojanowski JQ, Frosch MP, Baker MC, Rademakers R, Mesulam M, Bigio EH
Journal of neuropathology and experimental neurology 73 (5):467-73. PubMed PMID: 24709683
Published date: 2014 May
ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.
Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, Kawas CH, Cribbs DH, Bennett DA, Schneider JA, Larson EB, Crane PK, Valladares O, Schmitt
Acta neuropathologica 127 (6):825-43. PubMed PMID: 24770881
Published date: 2014 Apr 27
An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease.
Langbaum JB, Hendrix SB, Ayutyanont N, Chen K, Fleisher AS, Shah RC, Barnes LL, Bennett DA, Tariot PN, Reiman EM
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (6):666-74. PubMed PMID: 24751827
Published date: 2014 Apr 18
Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.
Counts SE, Alldred MJ, Che S, Ginsberg SD, Mufson EJ
Neuropharmacology. PubMed PMID: 24445080
Published date: 2014 Apr
Alzheimer's disease in African Americans: risk factors and challenges for the future.
Barnes LL, Bennett DA
Health affairs (Project Hope) 33 (4):580-6. PubMed PMID: 24711318
Published date: 2014 Apr
Association of Parkinson disease risk loci with mild parkinsonian signs in older persons.
Shulman JM, Yu L, Buchman AS, Evans DA, Schneider JA, Bennett DA, De Jager PL
JAMA neurology 71 (4):429-35. PubMed PMID: 24514572
Published date: 2014 Apr
Outcome markers for clinical trials in cerebral amyloid angiopathy.
Greenberg SM, Al-Shahi Salman R, Biessels GJ, van Buchem M, Cordonnier C, Lee JM, Montaner J, Schneider JA, Smith EE, Vernooij M, Werring DJ
The Lancet. Neurology 13 (4):419-28. PubMed PMID: 24581702
Published date: 2014 Apr
Interaction of transactive response DNA binding protein 43 with nuclear factor κB in mild cognitive impairment with episodic memory deficits.
Ohta Y, Tremblay C, Schneider JA, Bennett DA, Calon F, Julien JP
Acta neuropathologica communications 2 (1):37. PubMed PMID: 24690380
Published date: 2014 Apr 1
REST and stress resistance in ageing and Alzheimer's disease.
Lu T, Aron L, Zullo J, Pan Y, Kim H, Chen Y, Yang TH, Kim HM, Drake D, Liu XS, Bennett DA, Colaiácovo MP, Yankner BA
Nature 507 (7493):448-54. PubMed PMID: 24670762
Published date: 2014 Mar 27
Advances in the prevention of Alzheimer's disease and dementia.
Solomon A, Mangialasche F, Richard E, Andrieu S, Bennett DA, Breteler M, Fratiglioni L, Hooshmand B, Khachaturian AS, Schneider LS, Skoog I, Kivipelto M
Journal of internal medicine 275 (3):229-50. PubMed PMID: 24605807
Published date: 2014 Mar
Contribution of Alzheimer disease to mortality in the United States.
James BD, Leurgans SE, Hebert LE, Scherr PA, Yaffe K, Bennett DA
Neurology 82 (12):1045-50. PubMed PMID: 24598707
Published date: 2014 Mar 5
Ex vivo T2 relaxation: associations with age-related neuropathology and cognition.
Dawe RJ, Bennett DA, Schneider JA, Leurgans SE, Kotrotsou A, Boyle PA, Arfanakis K
Neurobiology of aging 35 (7):1549-61. PubMed PMID: 24582637
Published date: 2014 Feb 6
Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.
Bennett DA, Yu L, De Jager PL
Biochemical pharmacology 88 (4):617-630. PubMed PMID: 24508835
Published date: 2014 Feb 6
Gene-behavior interaction of depressive symptoms and the apolipoprotein E {varepsilon}4 allele on cognitive decline.
Rajan KB, Wilson RS, Skarupski KA, Mendes de Leon CF, Evans DA
Psychosomatic medicine 76 (2):101-8. PubMed PMID: 24434953
Published date: 2014 Feb
Astroglial heme oxygenase-1 and the origin of corpora amylacea in aging and degenerating neural tissues.
Song W, Zukor H, Liberman A, Kaduri S, Arvanitakis Z, Bennett DA, Schipper HM
Experimental neurology. PubMed PMID: 24440642
Published date: 2014 Jan 15
Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Rep
Vardarajan BN, Faber KM, Bird TD, Bennett DA, Rosenberg R, Boeve BF, Graff-Radford NR, Goate AM, Farlow M, Sweet RA, Lantigua R, Medrano MZ, Ottman R, Schaid DJ, Foroud TM, Mayeux R
JAMA neurology 71 (3):315-23. PubMed PMID: 24425039
Published date: 2014 Jan 13
Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment.
Leblanc AC, Ramcharitar J, Afonso V, Hamel E, Bennett DA, Pakavathkumar P, Albrecht S
Cell death and differentiation 21 (5):696-706. PubMed PMID: 24413155
Published date: 2014 Jan 10
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease.
Lee S, Zheng X, Krishnamoorthy J, Savelieff MG, Park HM, Brender JR, Kim JH, Derrick JS, Kochi A, Lee HJ, Kim C, Ramamoorthy A, Bowers MT, Lim MH
Journal of the American Chemical Society 136 (1):299-310. PubMed PMID: 24397771
Published date: 2014 Jan 8
Prefibrillar tau oligomers in mild cognitive impairment and Alzheimer's disease.
Mufson EJ, Ward S, Binder L
Neuro-degenerative diseases 13 (2-3):151-3. PubMed PMID: 24029627
Published date: 2014
Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates.
Dugger BN, Clark CM, Serrano G, Mariner M, Bedell BJ, Coleman RE, Doraiswamy PM, Lu M, Fleisher AS, Reiman EM, Sabbagh MN, Sadowsky CH, Schneider JA, Zehntner SP, Carpenter AP, Joshi AD, Mintun MA, Pontecorvo MJ, Skovronsky DM, Sue LI, Beach TG
Journal of neuropathology and experimental neurology 73 (1):72-80. PubMed PMID: 24335535
Published date: 2014 Jan
Prevalence of mixed pathologies in the aging brain.
Rahimi J, Kovacs GG
Alzheimer's research & therapy 6 (9):82. PubMed PMID: 25419243
Published date: 2014
Correlation between visual acuity and cognitive functions.
Elyashiv SM, Shabtai EL, Belkin M
The British journal of ophthalmology 98 (1):129-32. PubMed PMID: 24169658
Published date: 2014 Jan
Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.
Kelley CM, Powers BE, Velazquez R, Ash JA, Ginsberg SD, Strupp BJ, Mufson EJ
Brain pathology (Zurich, Switzerland) 24 (1):33-44. PubMed PMID: 23802663
Published date: 2014 Jan
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.
Raj T, Ryan KJ, Replogle JM, Chibnik LB, Rosenkrantz L, Tang A, Rothamel K, Stranger BE, Bennett DA, Evans DA, De Jager PL, Bradshaw EM
Human molecular genetics 23 (10):2729-36. PubMed PMID: 24381305
Published date: 2013 Dec 30
Cognitive and social lifestyle: links with neuropathology and cognition in late life.
Bennett DA, Arnold SE, Valenzuela MJ, Brayne C, Schneider JA
Acta neuropathologica 127 (1):137-50. PubMed PMID: 24356982
Published date: 2013 Dec 20
Age at surgical menopause influences cognitive decline and Alzheimer pathology in older women.
Bove R, Secor E, Chibnik LB, Barnes LL, Schneider JA, Bennett DA, De Jager PL
Neurology 82 (3):222-9. PubMed PMID: 24336141
Published date: 2013 Dec 11
Evidence needs to be translated, whether or not it is complete.
Dacks PA, Bennett DA, Fillit HM
JAMA neurology 71 (2):137-8. PubMed PMID: 24297103
Published date: 2013 Dec 2
Reply to Itzhaki and Klapper.
Lurain NS, Hanson BA, Martinson J, Leurgans SE, Landay AL, Bennett DA, Schneider JA
The Journal of infectious diseases 209 (6):974. PubMed PMID: 24280368
Published date: 2013 Nov 26
The SORL1 gene and convergent neural risk for Alzheimer's disease across the human lifespan.
Felsky D, Szeszko P, Yu L, Honer WG, De Jager PL, Schneider JA, Malhotra AK, Lencz T, Ikuta T, Pipitone J, Chakravarty MM, Lobaugh NJ, Mulsant BH, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN
Molecular psychiatry 19 (10):1125-32. PubMed PMID: 24166411
Published date: 2013 Oct 29
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Li
Nature genetics 45 (12):1452-8. PubMed PMID: 24162737
Published date: 2013 Oct 27
TREM2 and neurodegenerative disease.
Reitz C, Mayeux R
The New England journal of medicine 369 (16):1564-5. PubMed PMID: 24131184
Published date: 2013 Oct 17
Disentangling the effects of age and APOE on neuropathology and late life cognitive decline.
Yu L, Boyle PA, Leurgans S, Schneider JA, Bennett DA
Neurobiology of aging 35 (4):819-26. PubMed PMID: 24199961
Published date: 2013 Oct 9
Genetic susceptibility for ischemic infarction and arteriolosclerosis based on neuropathologic evaluations.
Chou SH, Shulman JM, Keenan BT, Secor EA, Buchman AS, Schneider J, Bennett DA, De Jager PL
Cerebrovascular diseases (Basel, Switzerland) 36 (3):181-8. PubMed PMID: 24135527
Published date: 2013
TDP-43 pathology, cognitive decline, and dementia in old age.
Wilson RS, Yu L, Trojanowski JQ, Chen EY, Boyle PA, Bennett DA, Schneider JA
JAMA neurology 70 (11):1418-24. PubMed PMID: 24080705
Published date: 2013 Sep 30
A 2-process model for neuropathology of Alzheimer's disease.
Mungas D, Tractenberg R, Schneider JA, Crane PK, Bennett DA
Neurobiology of aging 35 (2):301-8. PubMed PMID: 24080173
Published date: 2013 Sep 27
Distinct subcellular patterns of neprilysin protein and activity in the brains of Alzheimer's disease patients, transgenic mice and cultured human neuronal cells.
Zhou L, Wei C, Huang W, Bennett DA, Dickson DW, Wang R, Wang D
American journal of translational research 5 (6):608-621. PubMed PMID: 24093058
Published date: 2013
U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, Diner I, Heilman CJ, Rees HD, Wu H, Lin L, Szulwach KE, Gearing M, Mufson EJ, Bennett DA, Montine TJ, Seyfried NT, Wi
Proceedings of the National Academy of Sciences of the United States of America 110 (41):16562-16567. PubMed PMID: 24023061
Published date: 2013 Sep 10
Relation of neuropathology with cognitive decline among older persons without dementia.
Boyle PA, Yu L, Wilson RS, Schneider JA, Bennett DA
Frontiers in aging neuroscience. PubMed PMID: 24058343
Published date: 2013
Cerebrospinal fluid tau cleaved by caspase-6 reflects brain levels and cognition in aging and Alzheimer disease.
Ramcharitar J, Albrecht S, Afonso VM, Kaushal V, Bennett DA, Leblanc AC
Journal of neuropathology and experimental neurology 72 (9):824-832. PubMed PMID: 23965742
Published date: 2013 Sep
Cognitive frailty.
Buchman AS, Bennett DA
The journal of nutrition, health & aging 17 (9):738-9. PubMed PMID: 24154644
Published date: 2013
Charting a dynamic DNA methylation landscape of the human genome.
Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A
Nature 500 (7463):477-81. PubMed PMID: 23925113
Published date: 2013 Aug 7
Resilient brain aging: characterization of discordance between Alzheimer's disease pathology and cognition.
Negash S, Wilson R, Leurgans S, Wolk D, Schneider J, Buchman A, Bennett D, Arnold S
Current Alzheimer research 10 (8):844-851. PubMed PMID: 23919768
Published date: 2013 Aug 6
The PSEN1, p.E318G variant increases the risk of Alzheimer's disease in APOE-ε4 carriers.
Benitez BA, Karch CM, Cai Y, Jin SC, Cooper B, Carrell D, Bertelsen S, Chibnik L, Schneider JA, Bennett DA, Fagan AM, Holtzman D, Morris JC, Goate AM, Cruchaga C
PLoS genetics 9 (8):e1003685. PubMed PMID: 23990795
Published date: 2013 Aug
Very low levels of education and cognitive reserve: a clinicopathologic study.
Farfel JM, Nitrini R, Suemoto CK, Grinberg LT, Ferretti RE, Leite RE, Tampellini E, Lima L, Farias DS, Neves RC, Rodriguez RD, Menezes PR, Fregni F, Bennett DA, Pasqualucci CA, Jacob Filho W
Neurology 81 (7):650-657. PubMed PMID: 23873971
Published date: 2013 Jul 19
Aging, the central nervous system, and mobility.
Rosso AL, Studenski SA, Chen WG, Aizenstein HJ, Alexander NB, Bennett DA, Black SE, Camicioli R, Carlson MC, Ferrucci L, Guralnik JM, Hausdorff JM, Kaye J, Launer LJ, Lipsitz LA, Verghese J, Rosano C
The journals of gerontology. Series A, Biological sciences and medical sciences 68 (11):1379-86. PubMed PMID: 23843270
Published date: 2013 Jul 10
Genetic susceptibility for Alzheimer disease neuritic plaque pathology.
Shulman JM, Chen K, Keenan BT, Chibnik LB, Fleisher A, Thiyyagura P, Roontiva A, McCabe C, Patsopoulos NA, Corneveaux JJ, Yu L, Huentelman MJ, Evans DA, Schneider JA, Reiman EM, De Jager PL, Bennett DA
JAMA neurology 70 (9):1-7. PubMed PMID: 23836404
Published date: 2013 Jul 8
Caspase-6 activity predicts lower episodic memory ability in aged individuals.
Ramcharitar J, Afonso VM, Albrecht S, Bennett DA, LeBlanc AC
Neurobiology of aging 34 (7):1815-24. PubMed PMID: 23402898
Published date: 2013 Jul
PAK inactivation impairs social recognition in 3xTg-AD Mice without increasing brain deposition of tau and Aβ.
Arsenault D, Dal-Pan A, Tremblay C, Bennett DA, Guitton MJ, De Koninck Y, Tonegawa S, Calon F
The Journal of neuroscience : the official journal of the Society for Neuroscience 33 (26):10729-10740. PubMed PMID: 23804095
Published date: 2013 Jun 26
Much of late life cognitive decline is not due to common neurodegenerative pathologies.
Boyle PA, Wilson RS, Yu L, Barr AM, Honer WG, Schneider JA, Bennett DA
Annals of neurology 74 (3):478-489. PubMed PMID: 23798485
Published date: 2013 Jun 24
The red cell distribution width and anemia in association with prevalent dementia.
Weuve J, Mendes de Leon CF, Bennett DA, Dong X, Evans DA
Alzheimer disease and associated disorders 28 (2):99-105. PubMed PMID: 23751369
Published date: 2013 Jun 6
Cognitive decline in older persons initiating anticholinergic medications.
Shah RC, Janos AL, Kline JE, Yu L, Leurgans SE, Wilson RS, Wei P, Bennett DA, Heilman KM, Tsao JW
PloS one 8 (5):e64111. PubMed PMID: 23741303
Published date: 2013
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
Rietveld CA, Medland SE, Derringer J, Yang J, Esko T, Martin NW, Westra HJ, Shakhbazov K, Abdellaoui A, Agrawal A, Albrecht E, Alizadeh BZ, Amin N, Barnard J, Baumeister SE, Benke KS, Bielak LF, Boatman JA, Boyle PA, Davies G, de Leeuw C, Eklund N, E
Science (New York, N.Y.) 340 (6139):1467-1471. PubMed PMID: 23722424
Published date: 2013 May 30
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology.
Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, Rosenkrantz LL, Imboywa S, Lee M, Von Korff A, Morris MC, Evans DA, Johnson K, Sperling RA, Schneider JA, Bennett DA, De Jager PL
Nature neuroscience 16 (7):848-50. PubMed PMID: 23708142
Published date: 2013 May 23
Independent and epistatic effects of variants in VPS10-d receptors on Alzheimer disease risk and processing of the amyloid precursor protein (APP).
Reitz C, Tosto G, Vardarajan B, Rogaeva E, Ghani M, Rogers RS, Conrad C, Haines JL, Pericak-Vance MA, Fallin MD, Foroud T, Farrer LA, Schellenberg GD, George-Hyslop PS, Mayeux R
Translational psychiatry. PubMed PMID: 23673467
Published date: 2013 May 14
Virological and immunological characteristics of human cytomegalovirus infection associated with Alzheimer disease.
Lurain NS, Hanson BA, Martinson J, Leurgans SE, Landay AL, Bennett DA, Schneider JA
The Journal of infectious diseases 208 (4):564-72. PubMed PMID: 23661800
Published date: 2013 May 9
Principal components methods for narrow-sense heritability in the analysis of multidimensional longitudinal cognitive phenotypes.
Fung WL, Naylor MG, Bennett DA, Lange C, Blacker D
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 162 (7):770-8. PubMed PMID: 23650207
Published date: 2013 May 6
APOE ε4, Alzheimer's disease pathology, cerebrovascular disease, and cognitive change over the years prior to death.
Yu L, Boyle P, Schneider JA, Segawa E, Wilson RS, Leurgans S, Bennett DA
Psychology and aging 28 (4):1015-23. PubMed PMID: 23647000
Published date: 2013 May 6
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.
Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, Macdonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ,
Cell 153 (3):707-720. PubMed PMID: 23622250
Published date: 2013 Apr 25
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans.
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fa
JAMA : the journal of the American Medical Association 309 (14):1483-92. PubMed PMID: 23571587
Published date: 2013 Apr 10
Estimating cerebral microinfarct burden from autopsy samples.
Westover MB, Bianchi MT, Yang C, Schneider JA, Greenberg SM
Neurology 80 (15):1365-9. PubMed PMID: 23486880
Published date: 2013 Apr 9
Brain amyloid-β oligomers in ageing and Alzheimer's disease.
Lesné SE, Sherman MA, Grant M, Kuskowski M, Schneider JA, Bennett DA, Ashe KH
Brain : a journal of neurology 136 (Pt 5):1383-98. PubMed PMID: 23576130
Published date: 2013 Apr 9
An inflection point in gene discovery efforts for neurodegenerative diseases: from syndromic diagnoses toward endophenotypes and the epigenome.
De Jager PL, Bennett DA
JAMA neurology 70 (6):1-8. PubMed PMID: 23571780
Published date: 2013 Apr 9
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, Chibnik L, Bennett DA, Arnold SE, Harold D, Sims R, Gerrish A, Williams J, Van Deerlin VM, L
Neuron 78 (2):256-68. PubMed PMID: 23562540
Published date: 2013 Apr 3
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, Higuchi S, Ikeuchi T, Nishizawa M, Suga M, Kawase Y, Akatsu H, Kosaka K, Yamamoto T, Imagawa M
PloS one 8 (4):e58618. PubMed PMID: 23565137
Published date: 2013
What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function.
Hausdorff JM, Buchman AS
The journals of gerontology. Series A, Biological sciences and medical sciences 68 (4):409-11. PubMed PMID: 23401565
Published date: 2013 Apr
Sex difference in daily rhythms of clock gene expression in the aged human cerebral cortex.
Lim AS, Myers AJ, Yu L, Buchman AS, Duffy JF, De Jager PL, Bennett DA
Journal of biological rhythms 28 (2):117-29. PubMed PMID: 23606611
Published date: 2013 Apr
Sleep complaints and incident disability in a community-based cohort study of older persons.
Park M, Buchman AS, Lim AS, Leurgans SE, Bennett DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 22 (7):718-26. PubMed PMID: 23567404
Published date: 2013 Mar 25
Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Green RC
Alzheimer's & dementia : the journal of the Alzheimer's Association 10 (1):45-52. PubMed PMID: 23535033
Published date: 2013 Mar 24
Synapse stability in the precuneus early in the progression of Alzheimer's disease.
Scheff SW, Price DA, Schmitt FA, Roberts KN, Ikonomovic MD, Mufson EJ
Journal of Alzheimer's disease : JAD 35 (3):599-609. PubMed PMID: 23478309
Published date: 2013
Alternative Approaches in Gene Discovery and Characterization in Alzheimer's Disease.
Ertekin-Taner N, De Jager PL, Yu L, Bennett DA
Current genetic medicine reports 1 (1):39-51. PubMed PMID: 23482655
Published date: 2013 Mar
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, Engel A, Myers AJ, Corneveaux JJ, Huentelman MJ, Dillman A, Cookson MR, Reiman E
Annals of human genetics 77 (2):85-105. PubMed PMID: 23360175
Published date: 2013 Mar
Ex vivo MR volumetry of human brain hemispheres.
Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K
Magnetic resonance in medicine 71 (1):364-74. PubMed PMID: 23440751
Published date: 2013 Feb 25
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease.
Bennett DA, Hu WT, Holtzman D, Shaw L, Trojanowski J, Soares H
Neurology 80 (7):690-1. PubMed PMID: 23400321
Published date: 2013 Feb 12
Genome-wide chromatin state transitions associated with developmental and environmental cues.
Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE
Cell 152 (3):642-54. PubMed PMID: 23333102
Published date: 2013 Jan 31
Microvascular brain pathology and late-life motor impairment.
Buchman AS, Yu L, Boyle PA, Levine SR, Nag S, Schneider JA, Bennett DA
Neurology 80 (8):712-8. PubMed PMID: 23365057
Published date: 2013 Jan 30
High blood pressure and cognitive decline in mild cognitive impairment.
Goldstein FC, Levey AI, Steenland NK
Journal of the American Geriatrics Society 61 (1):67-73. PubMed PMID: 23301925
Published date: 2013 Jan
A genome-wide association study of depressive symptoms.
Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Ge
Biological psychiatry 73 (7):667-78. PubMed PMID: 23290196
Published date: 2013 Jan 2
An exploration of clinical dementia phenotypes among individuals with and without traumatic brain injury.
Dams-O'Connor K, Spielman L, Hammond FM, Sayed N, Culver C, Diaz-Arrastia R
NeuroRehabilitation 32 (2):199-209. PubMed PMID: 23535782
Published date: 2013 Jan 1
Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Turk M, Hardy J, Reiman EM, Saykin AJ
PloS one 7 (12):e50640. PubMed PMID: 23227193
Published date: 2012
AD pathology and cerebral infarctions are associated with memory and executive functioning one and five years before death.
Yang FM, Grigorenko A, Tommet D, Farias ST, Mungas D, Bennett DA, Jones RN, Crane PK
Journal of clinical and experimental neuropsychology 35 (1):24-34. PubMed PMID: 23205616
Published date: 2012 Dec 3
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, Brayne C, Gill M, Lawlor B, Lynch A, Craig D, McGuinness B, Johnston J, Holmes C, Living
Molecular psychiatry 17 (12):1316-27. PubMed PMID: 22005930
Published date: 2012 Dec
The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.
Larson M, Sherman MA, Amar F, Nuvolone M, Schneider JA, Bennett DA, Aguzzi A, Lesné SE
The Journal of neuroscience : the official journal of the Society for Neuroscience 32 (47):16857-16871. PubMed PMID: 23175838
Published date: 2012 Nov 21
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
Whitcomb DC, Larusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Albert MS, Albin RL, Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barnes LL, Beach TG, Beecham GW, Beekly D, B
Nature genetics 44 (12):1349-54. PubMed PMID: 23143602
Published date: 2012 Nov 11
Trends in Alzheimer's disease and dementia in the asian-pacific region.
Aggarwal NT, Tripathi M, Dodge HH, Alladi S, Anstey KJ
International journal of Alzheimer's disease. PubMed PMID: 23304631
Published date: 2012
Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study.
Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR
Neuroepidemiology 40 (2):73-84. PubMed PMID: 23095514
Published date: 2012 Oct 24
Molecular mechanisms of cortical degeneration in Parkinson disease.
Shulman JM, Schneider JA
Neurology 79 (17):1750-1. PubMed PMID: 23019261
Published date: 2012 Oct 23
GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.
Tsuang D, Leverenz JB, Lopez OL, Hamilton RL, Bennett DA, Schneider JA, Buchman AS, Larson EB, Crane PK, Kaye JA, Kramer P, Woltjer R, Kukull W, Nelson PT, Jicha GA, Neltner JH, Galasko D, Masliah E, Trojanowski JQ, Schellenberg GD, Yearout D, Huston
Neurology 79 (19):1944-1950. PubMed PMID: 23035075
Published date: 2012 Oct 3
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies.
Schneider JA, Arvanitakis Z, Yu L, Boyle PA, Leurgans SE, Bennett DA
Brain : a journal of neurology 135 (Pt 10):3005-14. PubMed PMID: 23065790
Published date: 2012 Oct
Relation of neuropathology to cognition in persons without cognitive impairment.
Bennett DA, Wilson RS, Boyle PA, Buchman AS, Schneider JA
Annals of neurology 72 (4):599-609. PubMed PMID: 23109154
Published date: 2012 Oct
The natural history of cognitive decline in Alzheimer's disease.
Wilson RS, Segawa E, Boyle PA, Anagnos SE, Hizel LP, Bennett DA
Psychology and aging 27 (4):1008-17. PubMed PMID: 22946521
Published date: 2012 Sep 3
Analysis of copy number variation in Alzheimer's disease: the NIALOAD/ NCRAD Family Study.
Swaminathan S, Shen L, Kim S, Inlow M, West JD, Faber KM, Foroud T, Mayeux R, Saykin AJ
Current Alzheimer research 9 (7):801-14. PubMed PMID: 22486522
Published date: 2012 Sep
High CRP with "normal" cognition: a resilient phenotype in old age.
Buchman AS, Bennett DA
Neurology 79 (11):1078-9. PubMed PMID: 22895579
Published date: 2012 Aug 15
Reply.
Buchman AS, Shulman JM, Leurgans SE, Schneider JA, Bennett DA
Annals of neurology 72 (2):298. PubMed PMID: 22926865
Published date: 2012 Aug
Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.
Larson ME, Sherman MA, Greimel S, Kuskowski M, Schneider JA, Bennett DA, Lesné SE
The Journal of neuroscience : the official journal of the Society for Neuroscience 32 (30):10253-66. PubMed PMID: 22836259
Published date: 2012 Jul 25
TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease.
Valant V, Keenan BT, Anderson CD, Shulman JM, Devan WJ, Ayres AM, Schwab K, Goldstein JN, Viswanathan A, Greenberg SM, Bennett DA, De Jager PL, Rosand J, Biffi A
Translational stroke research 3 (Suppl 1):102-12. PubMed PMID: 24323865
Published date: 2012 Jul
Age-related changes in parahippocampal white matter integrity: a diffusion tensor imaging study.
Rogalski E, Stebbins GT, Barnes CA, Murphy CM, Stoub TR, George S, Ferrari C, Shah RC, deToledo-Morrell L
Neuropsychologia 50 (8):1759-65. PubMed PMID: 22561887
Published date: 2012 Jul
Alzheimer's disease can spare local metacognition despite global anosognosia: revisiting the confidence-accuracy relationship in episodic memory.
Gallo DA, Cramer SJ, Wong JT, Bennett DA
Neuropsychologia 50 (9):2356-64. PubMed PMID: 22722068
Published date: 2012 Jul
Longitudinal epidemiologic clinical-pathologic studies of aging and Alzheimer's disease.
Bennett DA, Launer LJ
Current Alzheimer research 9 (6):617-20. PubMed PMID: 22715984
Published date: 2012 Jul
Overview and findings from the religious orders study.
Bennett DA, Schneider JA, Arvanitakis Z, Wilson RS
Current Alzheimer research 9 (6):628-45. PubMed PMID: 22471860
Published date: 2012 Jul
Age-related changes in the mesial temporal lobe: the parahippocampal white matter region.
Stoub TR, Barnes CA, Shah RC, Stebbins GT, Ferrari C, deToledo-Morrell L
Neurobiology of aging 33 (7):1168-76. PubMed PMID: 21459484
Published date: 2012 Jul
The Minority Aging Research Study: ongoing efforts to obtain brain donation in African Americans without dementia.
Barnes LL, Shah RC, Aggarwal NT, Bennett DA, Schneider JA
Current Alzheimer research 9 (6):734-45. PubMed PMID: 22471868
Published date: 2012 Jul
Selected findings from the Religious Orders Study and Rush Memory and Aging Project.
Bennett DA, Wilson RS, Arvanitakis Z, Boyle PA, de Toledo-Morrell L, Schneider JA
Journal of Alzheimer's disease : JAD 33 (0):S397-403. PubMed PMID: 22647261
Published date: 2012 May 29
Terminal decline in motor function.
Wilson RS, Segawa E, Buchman AS, Boyle PA, Hizel LP, Bennett DA
Psychology and aging 27 (4):998-1007. PubMed PMID: 22612603
Published date: 2012 May 21
Dementia from Alzheimer disease and mixed pathologies in the oldest old.
James BD, Bennett DA, Boyle PA, Leurgans S, Schneider JA
JAMA 307 (17):1798-800. PubMed PMID: 22550192
Published date: 2012 May 2
Common variants at 12q14 and 12q24 are associated with hippocampal volume.
Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA
Nature genetics 44 (5):545-51. PubMed PMID: 22504421
Published date: 2012 May
Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease.
Arnold SE, Louneva N, Cao K, Wang LS, Han LY, Wolk DA, Negash S, Leurgans SE, Schneider JA, Buchman AS, Wilson RS, Bennett DA
Neurobiology of aging 34 (1):157-68. PubMed PMID: 22554416
Published date: 2012 May 1
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature.
Nelson PT, Alafuzoff I, Bigio EH, Bouras C, Braak H, Cairns NJ, Castellani RJ, Crain BJ, Davies P, Del Tredici K, Duyckaerts C, Frosch MP, Haroutunian V, Hof PR, Hulette CM, Hyman BT, Iwatsubo T, Jellinger KA, Jicha GA, Kövari E, Kukull WA, Leverenz
Journal of neuropathology and experimental neurology 71 (5):362-81. PubMed PMID: 22487856
Published date: 2012 May
Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory.
Barral S, Bird T, Goate A, Farlow MR, Diaz-Arrastia R, Bennett DA, Graff-Radford N, Boeve BF, Sweet RA, Stern Y, Wilson RS, Foroud T, Ott J, Mayeux R
Neurology 78 (19):1464-1471. PubMed PMID: 22539578
Published date: 2012 Apr 25
Terminal dedifferentiation of cognitive abilities.
Wilson RS, Segawa E, Hizel LP, Boyle PA, Bennett DA
Neurology 78 (15):1116-22. PubMed PMID: 22491858
Published date: 2012 Apr 10
Alzheimer disease susceptibility loci: evidence for a protein network under natural selection.
Raj T, Shulman JM, Keenan BT, Chibnik LB, Evans DA, Bennett DA, Stranger BE, De Jager PL
American journal of human genetics 90 (4):720-6. PubMed PMID: 22482808
Published date: 2012 Apr 6
Hippocampal drebrin loss in mild cognitive impairment.
Counts SE, He B, Nadeem M, Wuu J, Scheff SW, Mufson EJ
Neuro-degenerative diseases 10 (1-4):216-9. PubMed PMID: 22310934
Published date: 2012
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE
The Journal of clinical investigation 122 (4):1316-38. PubMed PMID: 22476197
Published date: 2012 Mar 22
Cerebral microinfarcts: the invisible lesions.
Smith EE, Schneider JA, Wardlaw JM, Greenberg SM
The Lancet. Neurology 11 (3):272-82. PubMed PMID: 22341035
Published date: 2012 Mar
Cerebral microinfarcts: the invisible lesions.
Smith EE, Schneider JA, Wardlaw JM, Greenberg SM
The Lancet. Neurology 11 (3):272-82. PubMed PMID: 22341035
Published date: 2012 Mar
Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Pankratz N, Beecham GW, DeStefano AL, Dawson TM, Doheny KF, Factor SA, Hamza TH, Hung AY, Hyman BT, Ivinson AJ, Krainc D, Latourelle JC, Clark LN, Marder K, Martin ER, Mayeux R, Ross OA, Scherzer CR, Simon DK, Tanner C, Vance JM, Wszolek ZK, Zabetian
Annals of neurology 71 (3):370-84. PubMed PMID: 22451204
Published date: 2012 Mar
Patterns of focal gray matter atrophy are associated with bradykinesia and gait disturbances in older adults.
Rosano C, Bennett DA, B Newman A, Venkatraman V, Yaffe K, Harris T, Kritchevsky S, J Aizenstein H
The journals of gerontology. Series A, Biological sciences and medical sciences 67 (9):957-62. PubMed PMID: 22367436
Published date: 2012 Feb 24
Plasma biomarkers of depressive symptoms in older adults.
Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, Wilson RS, Shaw LM
Translational psychiatry. PubMed PMID: 22832727
Published date: 2012 Feb 21
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline.
Keenan BT, Shulman JM, Chibnik LB, Raj T, Tran D, Sabuncu MR, Allen AN, Corneveaux JJ, Hardy JA, Huentelman MJ, Lemere CA, Myers AJ, Nicholson-Weller A, Reiman EM, Evans DA, Bennett DA, De Jager PL
Human molecular genetics 21 (10):2377-2388. PubMed PMID: 22343410
Published date: 2012 Feb 17
Recruitment and enrollment of caregivers for a lifestyle physical activity clinical trial.
Etkin CD, Farran CJ, Barnes LL, Shah RC
Research in nursing & health 35 (1):70-81. PubMed PMID: 22083931
Published date: 2012 Feb
Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease.
Perez SE, Getova DP, He B, Counts SE, Geula C, Desire L, Coutadeur S, Peillon H, Ginsberg SD, Mufson EJ
The American journal of pathology 180 (2):526-40. PubMed PMID: 22142809
Published date: 2012 Feb
Rare variants in APP, PSEN1 and PSEN2 increase risk for AD in late-onset Alzheimer's disease families.
Cruchaga C, Haller G, Chakraverty S, Mayo K, Vallania FL, Mitra RD, Faber K, Williamson J, Bird T, Diaz-Arrastia R, Foroud TM, Boeve BF, Graff-Radford NR, St Jean P, Lawson M, Ehm MG, Mayeux R, Goate AM
PloS one 7 (2):e31039. PubMed PMID: 22312439
Published date: 2012
Nigral pathology and parkinsonian signs in elders without Parkinson disease.
Buchman AS, Shulman JM, Nag S, Leurgans SE, Arnold SE, Morris MC, Schneider JA, Bennett DA
Annals of neurology 71 (2):258-66. PubMed PMID: 22367997
Published date: 2012 Feb
Genetic variation at CR1 increases risk of cerebral amyloid angiopathy.
Biffi A, Shulman JM, Jagiella JM, Cortellini L, Ayres AM, Schwab K, Brown DL, Silliman SL, Selim M, Worrall BB, Meschia JF, Slowik A, De Jager PL, Greenberg SM, Schneider JA, Bennett DA, Rosand J
Neurology 78 (5):334-41. PubMed PMID: 22262751
Published date: 2012 Jan 31
Amyloid pathology in persons with "normal" cognition.
Buchman AS, Bennett DA
Neurology 78 (4):228-229. PubMed PMID: 22189449
Published date: 2012 Jan 24
A random change point model for cognitive decline in Alzheimer's disease and mild cognitive impairment.
Yu L, Boyle P, Wilson RS, Segawa E, Leurgans S, De Jager PL, Bennett DA
Neuroepidemiology 39 (2):73-83. PubMed PMID: 22814083
Published date: 2012
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Kouri N, Kolbert CP, Jen J, Haines JL, Mayeux R, Perica
PLoS genetics 8 (6):e1002707. PubMed PMID: 22685416
Published date: 2012
Mild cognitive impairment: pathology and mechanisms.
Mufson EJ, Binder L, Counts SE, DeKosky ST, de Toledo-Morrell L, Ginsberg SD, Ikonomovic MD, Perez SE, Scheff SW
Acta neuropathologica 123 (1):13-30. PubMed PMID: 22101321
Published date: 2012 Jan
Altered NEP2 expression and activity in mild cognitive impairment and Alzheimer's disease.
Huang JY, Hafez DM, James BD, Bennett DA, Marr RA
Journal of Alzheimer's disease : JAD 28 (2):433-41. PubMed PMID: 22008264
Published date: 2012 Jan 1
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach.
Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, Hyman BT
Acta neuropathologica 123 (1):1-11. PubMed PMID: 22101365
Published date: 2012 Jan
Evidence for angiogenesis in Parkinson's disease, incidental Lewy body disease, and progressive supranuclear palsy.
Desai Bradaric B, Patel A, Schneider JA, Carvey PM, Hendey B
Journal of neural transmission (Vienna, Austria : 1996) 119 (1):59-71. PubMed PMID: 21748523
Published date: 2012 Jan
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease.
Hyman BT, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Carrillo MC, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Thies B, Trojanowski JQ, Vinters HV, Montine TJ
Alzheimer's & dementia : the journal of the Alzheimer's Association 8 (1):1-13. PubMed PMID: 22265587
Published date: 2012 Jan
Correlation of amyloid PET ligand florbetapir F 18 binding with Aβ aggregation and neuritic plaque deposition in postmortem brain tissue.
Choi SR, Schneider JA, Bennett DA, Beach TG, Bedell BJ, Zehntner SP, Krautkramer MJ, Kung HF, Skovronsky DM, Hefti F, Clark CM
Alzheimer disease and associated disorders 26 (1):8-16. PubMed PMID: 22354138
Published date: 2012 Jan
A genome-wide scan for common variants affecting the rate of age-related cognitive decline.
De Jager PL, Shulman JM, Chibnik LB, Keenan BT, Raj T, Wilson RS, Yu L, Leurgans SE, Tran D, Aubin C, Anderson CD, Biffi A, Corneveaux JJ, Huentelman MJ, Rosand J, Daly MJ, Myers AJ, Reiman EM, Bennett DA, Evans DA
Neurobiology of aging 33 (5):1017.e1-1017.e15. PubMed PMID: 22054870
Published date: 2011 Nov 3
Cerebrovascular disease pathology and parkinsonian signs in old age.
Buchman AS, Leurgans SE, Nag S, Bennett DA, Schneider JA
Stroke 42 (11):3183-9. PubMed PMID: 21885844
Published date: 2011 Nov
Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Vana L, Kanaan NM, Ugwu IC, Wuu J, Mufson EJ, Binder LI
The American journal of pathology 179 (5):2533-50. PubMed PMID: 21945902
Published date: 2011 Nov
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast.
Treusch S, Hamamichi S, Goodman JL, Matlack KE, Chung CY, Baru V, Shulman JM, Parrado A, Bevis BJ, Valastyan JS, Han H, Lindhagen-Persson M, Reiman EM, Evans DA, Bennett DA, Olofsson A, Dejager PL, Tanzi RE, Caldwell KA, Caldwell GA, Lindquist S
Science (New York, N.Y.) 334 (6060):1241-5. PubMed PMID: 22033521
Published date: 2011 Oct 27
Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Mufson EJ, Alldred MJ, Counts SE, Wuu J, Nixon RA, Che S
Journal of chemical neuroanatomy 42 (2):102-10. PubMed PMID: 21669283
Published date: 2011 Oct
Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease.
Counts SE, Che S, Ginsberg SD, Mufson EJ
Journal of chemical neuroanatomy 42 (2):111-7. PubMed PMID: 21397006
Published date: 2011 Oct
Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease.
Counts SE, Che S, Ginsberg SD, Mufson EJ
Journal of chemical neuroanatomy 42 (2):111-7. PubMed PMID: 21397006
Published date: 2011 Oct
Cognitive decline in the elderly: an analysis of population heterogeneity.
Hayden KM, Reed BR, Manly JJ, Tommet D, Pietrzak RH, Chelune GJ, Yang FM, Revell AJ, Bennett DA, Jones RN
Age and ageing 40 (6):684-9. PubMed PMID: 21890481
Published date: 2011 Sep 2
Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease.
Tremblay C, St-Amour I, Schneider J, Bennett DA, Calon F
Journal of neuropathology and experimental neurology 70 (9):788-98. PubMed PMID: 21865887
Published date: 2011 Sep
Improving the pharmacologic management of pain in older adults: identifying the research gaps and methods to address them.
Reid MC, Bennett DA, Chen WG, Eldadah BA, Farrar JT, Ferrell B, Gallagher RM, Hanlon JT, Herr K, Horn SD, Inturrisi CE, Lemtouni S, Lin YW, Michaud K, Morrison RS, Neogi T, Porter LL, Solomon DH, Von Korff M, Weiss K, Witter J, Zacharoff KL
Pain medicine (Malden, Mass.) 12 (9):1336-1357. PubMed PMID: 21834914
Published date: 2011 Aug 11
ELISA measurement of specific non-antigen-bound antibodies to Aβ1-42 monomer and soluble oligomers in sera from Alzheimer's disease, mild cognitively impaired, and noncognitively impaired subjects.
Klaver AC, Coffey MP, Smith LM, Bennett DA, Finke JM, Dang L, Loeffler DA
Journal of neuroinflammation 8 (1):93. PubMed PMID: 21827691
Published date: 2011 Aug 9
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association.
Gorelick PB, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, Launer LJ, Laurent S, Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C, Arnett DK, Bennett DA, Chui HC, Higashida RT, Lindquist R, Nilsson PM, Roman GC, Sellke FW, Sesha
Stroke 42 (9):2672-2713. PubMed PMID: 21778438
Published date: 2011 Jul 21
Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease.
Ikonomovic MD, Klunk WE, Abrahamson EE, Wuu J, Mathis CA, Scheff SW, Mufson EJ, DeKosky ST
Neurology 77 (1):39-47. PubMed PMID: 21700583
Published date: 2011 Jul 5
Datasets for special series on cognitive reserve.
Bennett DA, Barnes LL
Journal of the International Neuropsychological Society : JINS 17 (4):587-92. PubMed PMID: 23131599
Published date: 2011 Jul
Cognitive activities during adulthood are more important than education in building reserve.
Reed BR, Dowling M, Tomaszewski Farias S, Sonnen J, Strauss M, Schneider JA, Bennett DA, Mungas D
Journal of the International Neuropsychological Society : JINS 17 (4):615-24. PubMed PMID: 23131600
Published date: 2011 Jul
Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
Ewers M, Schmitz S, Hansson O, Walsh C, Fitzpatrick A, Bennett D, Minthon L, Trojanowski JQ, Shaw LM, Faluyi YO, Vellas B, Dubois B, Blennow K, Buerger K, Teipel SJ, Weiner M, Hampel H
Neurobiology of aging 33 (8):1599-608. PubMed PMID: 21684041
Published date: 2011 Jun 16
Entorhinal cortex volume is associated with episodic memory related brain activation in normal aging and amnesic mild cognitive impairment.
Trivedi MA, Stoub TR, Murphy CM, George S, deToledo-Morrell L, Shah RC, Whitfield-Gabrieli S, Gabrieli JD, Stebbins GT
Brain imaging and behavior 5 (2):126-36. PubMed PMID: 21328083
Published date: 2011 Jun
Uncovering the genetic architecture of white matter disease.
Aggarwal NT, De Jager PL
Annals of neurology 69 (6):907-8. PubMed PMID: 21681793
Published date: 2011 Jun
Cognition and neuropathology in aging: multidimensional perspectives from the Rush Religious Orders Study and Rush Memory And Aging Project.
Negash S, Bennett DA, Wilson RS, Schneider JA, Arnold SE
Current Alzheimer research 8 (4):336-40. PubMed PMID: 21222592
Published date: 2011 Jun
Assessment of cognition in early dementia.
Silverberg NB, Ryan LM, Carrillo MC, Sperling R, Petersen RC, Posner HB, Snyder PJ, Hilsabeck R, Gallagher M, Raber J, Rizzo A, Possin K, King J, Kaye J, Ott BR, Albert MS, Wagster MV, Schinka JA, Cullum CM, Farias ST, Balota D, Rao S, Loewenstein D,
Alzheimer's & dementia : the journal of the Alzheimer's Association 7 (3):e60-e76. PubMed PMID: 23559893
Published date: 2011 May 1
Assessing family caregiver skill in managing behavioral symptoms of Alzheimer's disease.
Farran CJ, Fogg LG, McCann JJ, Etkin C, Dong X, Barnes LL
Aging & mental health 15 (4):510-21. PubMed PMID: 21500018
Published date: 2011 May
Loss of motor function in preclinical Alzheimer's disease.
Buchman AS, Bennett DA
Expert review of neurotherapeutics 11 (5):665-76. PubMed PMID: 21539487
Published date: 2011 May
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kau
Nature genetics 43 (5):436-41. PubMed PMID: 21460841
Published date: 2011 May
Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.
Bruno AM, Huang JY, Bennett DA, Marr RA, Hastings ML, Stutzmann GE
Neurobiology of aging 33 (5):1001.e1-6. PubMed PMID: 21531043
Published date: 2011 Apr 29
Alzheimer-signature MRI biomarker predicts AD dementia in cognitively normal adults.
Dickerson BC, Stoub TR, Shah RC, Sperling RA, Killiany RJ, Albert MS, Hyman BT, Blacker D, Detoledo-Morrell L
Neurology 76 (16):1395-402. PubMed PMID: 21490323
Published date: 2011 Apr 19
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.
Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, Gearing M, Beach TG, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF,
Archives of neurology 68 (4):488-97. PubMed PMID: 21482928
Published date: 2011 Apr
Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration.
Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, Gearing M, Beach TG, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF,
Archives of neurology 68 (4):488-97. PubMed PMID: 21482928
Published date: 2011 Apr
Smoking in midlife and dementia in old age: risk across the life course.
James BD, Bennett DA
Archives of neurology 68 (3):365-8. PubMed PMID: 21403022
Published date: 2011 Mar
CR1 is associated with amyloid plaque burden and age-related cognitive decline.
Chibnik LB, Shulman JM, Leurgans SE, Schneider JA, Wilson RS, Tran D, Aubin C, Buchman AS, Heward CB, Myers AJ, Hardy JA, Huentelman MJ, Corneveaux JJ, Reiman EM, Evans DA, Bennett DA, De Jager PL
Annals of neurology 69 (3):560-9. PubMed PMID: 21391232
Published date: 2011 Mar
Microinfarct pathology, dementia, and cognitive systems.
Arvanitakis Z, Leurgans SE, Barnes LL, Bennett DA, Schneider JA
Stroke 42 (3):722-7. PubMed PMID: 21212395
Published date: 2011 Mar
Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment.
Wilson RS, Leurgans SE, Boyle PA, Bennett DA
Archives of neurology 68 (3):351-6. PubMed PMID: 21403020
Published date: 2011 Mar
Functional screening of Alzheimer pathology genome-wide association signals in Drosophila.
Shulman JM, Chipendo P, Chibnik LB, Aubin C, Tran D, Keenan BT, Kramer PL, Schneider JA, Bennett DA, Feany MB, De Jager PL
American journal of human genetics 88 (2):232-8. PubMed PMID: 21295279
Published date: 2011 Feb 11
Analysis of postmortem ventricular cerebrospinal fluid from patients with and without dementia indicates association of vitamin E with neuritic plaques and specific measures of cognitive performance.
Hensley K, Barnes LL, Christov A, Tangney C, Honer WG, Schneider JA, Bennett DA, Morris MC
Journal of Alzheimer's disease : JAD 24 (4):767-74. PubMed PMID: 21321395
Published date: 2011
Synaptic loss in the inferior temporal gyrus in mild cognitive impairment and Alzheimer's disease.
Scheff SW, Price DA, Schmitt FA, Scheff MA, Mufson EJ
Journal of Alzheimer's disease : JAD 24 (3):547-57. PubMed PMID: 21297265
Published date: 2011
Cerebral amyloid angiopathy pathology and cognitive domains in older persons.
Arvanitakis Z, Leurgans SE, Wang Z, Wilson RS, Bennett DA, Schneider JA
Annals of neurology 69 (2):320-7. PubMed PMID: 21387377
Published date: 2011 Feb
Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE.
Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, Mayeux R
PLoS genetics 7 (2):e1001308. PubMed PMID: 21379329
Published date: 2011 Feb
Musculoskeletal pain is associated with incident mobility disability in community-dwelling elders.
Shah RC, Buchman AS, Boyle PA, Leurgans SE, Wilson RS, Andersson GB, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 66 (1):82-8. PubMed PMID: 20966101
Published date: 2011 Jan
Heritability of different forms of memory in the Late Onset Alzheimer's Disease Family Study.
Wilson RS, Barral S, Lee JH, Leurgans SE, Foroud TM, Sweet RA, Graff-Radford N, Bird TD, Mayeux R, Bennett DA
Journal of Alzheimer's disease : JAD 23 (2):249-55. PubMed PMID: 20930268
Published date: 2011
Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study.
Dawe RJ, Bennett DA, Schneider JA, Arfanakis K
PloS one 6 (10):e26286. PubMed PMID: 22043314
Published date: 2011
Neuropathological associates of multiple cognitive functions in two community-based cohorts of older adults.
Dowling NM, Tomaszewski Farias S, Reed BR, Sonnen JA, Strauss ME, Schneider JA, Bennett DA, Mungas D
Journal of the International Neuropsychological Society : JINS 17 (4):1-13. PubMed PMID: 21092373
Published date: 2010 Nov 22
Antemortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies.
Kantarci K, Yang C, Schneider JA, Senjem ML, Reyes DA, Lowe VJ, Barnes LL, Aggarwal NT, Bennett DA, Smith GE, Petersen RC, Jack CR, Boeve BF
Neurobiology of aging 33 (5):878-85. PubMed PMID: 20961664
Published date: 2010 Oct 18
False recollection of emotional pictures in Alzheimer's disease.
Gallo DA, Foster KT, Wong JT, Bennett DA
Neuropsychologia 48 (12):3614-8. PubMed PMID: 20727904
Published date: 2010 Oct
Where vascular meets neurodegenerative disease.
Schneider JA, Bennett DA
Stroke 41 (10 Suppl):S144-6. PubMed PMID: 20876491
Published date: 2010 Oct
Is there a link between cancer and Alzheimer disease?
Bennett DA
Neurology 75 (13):1216-7. PubMed PMID: 20922851
Published date: 2010 Sep 28
Neurodegenerative basis of age-related cognitive decline.
Wilson RS, Leurgans SE, Boyle PA, Schneider JA, Bennett DA
Neurology 75 (12):1070-8. PubMed PMID: 20844243
Published date: 2010 Sep 21
Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Mufson EJ, Counts SE, Wuu J, Alldred MJ, Nixon RA, Che S
Journal of Alzheimer's disease : JAD 22 (2):631-639. PubMed PMID: 20847427
Published date: 2010 Aug 30
Loss of basic lexical knowledge in old age.
Wilson RS, Krueger KR, Boyle PA, Bennett DA
Journal of neurology, neurosurgery, and psychiatry 82 (4):369-72. PubMed PMID: 20802026
Published date: 2010 Aug 27
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes.
Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Ma
Archives of neurology 67 (12):1473-1484. PubMed PMID: 20697030
Published date: 2010 Aug 9
Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression.
Ginsberg SD, Alldred MJ, Counts SE, Cataldo AM, Neve RL, Jiang Y, Wuu J, Chao MV, Mufson EJ, Nixon RA, Che S
Biological psychiatry 68 (10):885-93. PubMed PMID: 20655510
Published date: 2010 Jul 22
Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain.
Wang S, Wang R, Chen L, Bennett DA, Dickson DW, Wang DS
Journal of neurochemistry 115 (1):47-57. PubMed PMID: 20663017
Published date: 2010 Jul 17
Iterative image reconstruction for PROPELLER-MRI using the nonuniform fast fourier transform.
Tamhane AA, Anastasio MA, Gui M, Arfanakis K
Journal of magnetic resonance imaging : JMRI 32 (1):211-7. PubMed PMID: 20578028
Published date: 2010 Jul
Telephone assessment of cognitive function in the late-onset Alzheimer's disease family study.
Wilson RS, Leurgans SE, Foroud TM, Sweet RA, Graff-Radford N, Mayeux R, Bennett DA
Archives of neurology 67 (7):855-61. PubMed PMID: 20625093
Published date: 2010 Jul
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, Nalls MA, Chen K, Lee W, Chewning K, Villa SE, Meechoovet HB, Gerber JD, Frost D, Benson HL, O'Reilly S, Chibnik LB, Shulman JM, Singleton AB, Craig DW, Van Keuren-Jensen KR, Dunckley
Human molecular genetics 19 (16):3295-301. PubMed PMID: 20534741
Published date: 2010 Jun 9
Staff training in assisted living: evaluating treatment fidelity.
Teri L, McKenzie GL, Pike KC, Farran CJ, Beck C, Paun O, Lafazia D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 18 (6):502-9. PubMed PMID: 19910884
Published date: 2010 Jun
Alzheimer disease pathology in cognitively healthy elderly: a genome-wide study.
Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J
Neurobiology of aging 32 (12):2113-22. PubMed PMID: 20452100
Published date: 2010 May 6
Association of anxiety and depression with microtubule-associated protein 2- and synaptopodin-immunolabeled dendrite and spine densities in hippocampal CA3 of older humans.
Soetanto A, Wilson RS, Talbot K, Un A, Schneider JA, Sobiesk M, Kelly J, Leurgans S, Bennett DA, Arnold SE
Archives of general psychiatry 67 (5):448-57. PubMed PMID: 20439826
Published date: 2010 May
Identification of Caspase-6-mediated processing of the valosin containing protein (p97) in Alzheimer's disease: a novel link to dysfunction in ubiquitin proteasome system-mediated protein degradation.
Halawani D, Tessier S, Anzellotti D, Bennett DA, Latterich M, LeBlanc AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 30 (17):6132-42. PubMed PMID: 20427671
Published date: 2010 Apr 28
Inability of plasma and urine F2A-isoprostane levels to differentiate mild cognitive impairment from Alzheimer's disease.
Mufson EJ, Leurgans S
Neuro-degenerative diseases 7 (1-3):139-42. PubMed PMID: 20197693
Published date: 2010
Atrophy and dysfunction of parahippocampal white matter in mild Alzheimer's disease.
Wang C, Stebbins GT, Medina DA, Shah RC, Bammer R, Moseley ME, Detoledo-Morrell L
Neurobiology of aging 33 (1):43-52. PubMed PMID: 20359781
Published date: 2010 Mar 30
Cortical M1 receptor concentration increases without a concomitant change in function in Alzheimer's disease.
Overk CR, Felder CC, Tu Y, Schober DA, Bales KR, Wuu J, Mufson EJ
Journal of chemical neuroanatomy 40 (1):63-70. PubMed PMID: 20347961
Published date: 2010 Mar 27
Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.
Mufson EJ, Wuu J, Counts SE, Nykjaer A
Neuroscience letters 471 (3):129-33. PubMed PMID: 20085800
Published date: 2010 Mar 8
Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.
Mufson EJ, Wuu J, Counts SE, Nykjaer A
Neuroscience letters 471 (3):129-33. PubMed PMID: 20085800
Published date: 2010 Mar 8
PUTATIVE CSF PROTEIN BIOMARKER CANDIDATES FOR AMNESTIC MILD COGNITIVE IMPAIRMENT.
Counts SE, Mufson EJ
Translational neuroscience 1 (1):2-8. PubMed PMID: 21311725
Published date: 2010 Mar 1
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, van Swieten JC, Murrell JR, Ghetti B, Spina S, Grafm
Nature genetics 42 (3):234-9. PubMed PMID: 20154673
Published date: 2010 Feb 14
Assessment and familial aggregation of psychosis in Alzheimer's disease from the National Institute on Aging Late Onset Alzheimer's Disease Family Study.
Sweet RA, Bennett DA, Graff-Radford NR, Mayeux R
Brain : a journal of neurology 133 (Pt 4):1155-1162. PubMed PMID: 20147454
Published date: 2010 Feb 10
Parkinsonian signs and incident falls in older persons without Parkinson's disease.
Buracchio T, Arvanitakis Z, Leurgans S, Bennett DA
Journal of the American Geriatrics Society 58 (1):205-6. PubMed PMID: 20122072
Published date: 2010 Jan
Neuroprotective role for galanin in Alzheimer's disease.
Counts SE, Perez SE, Ginsberg SD, Mufson EJ
Experientia supplementum (2012) 102 (11):143-62. PubMed PMID: 21299067
Published date: 2010
Neuroprotective role for galanin in Alzheimer's disease.
Counts SE, Perez SE, Ginsberg SD, Mufson EJ
Experientia supplementum (2012) 102 (11):143-62. PubMed PMID: 21299067
Published date: 2010
Intermediate phenotypes identify divergent pathways to Alzheimer's disease.
Shulman JM, Chibnik LB, Aubin C, Schneider JA, Bennett DA, De Jager PL
PloS one 5 (6):e11244. PubMed PMID: 20574532
Published date: 2010
Is there a link between cancer and Alzheimer disease?
Bennett DA, Leurgans S
Neurology 74 (2):100-1. PubMed PMID: 20032287
Published date: 2009 Dec 23
Subregional neuroanatomical change as a biomarker for Alzheimer's disease.
Holland D, Brewer JB, Hagler DJ, Fenema-Notestine C, Dale AM, Weiner M, Thal L, Petersen R, Jack CR, Jagust W, Trojanowki J, Toga AW, Beckett L, Green RC, Gamst A, Potter WZ, Montine T, Anders D, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, A
Proceedings of the National Academy of Sciences of the United States of America 106 (49):20954-20959. PubMed PMID: 19996185
Published date: 2009 Dec 8
Increased matrix metalloproteinase 9 activity in mild cognitive impairment.
Bruno MA, Mufson EJ, Wuu J, Cuello AC
Journal of neuropathology and experimental neurology 68 (12):1309-18. PubMed PMID: 19915485
Published date: 2009 Dec
Increased matrix metalloproteinase 9 activity in mild cognitive impairment.
Bruno MA, Mufson EJ, Wuu J, Cuello AC
Journal of neuropathology and experimental neurology 68 (12):1309-18. PubMed PMID: 19915485
Published date: 2009 Dec
Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Journal of Alzheimer's disease : JAD 18 (4):885-96. PubMed PMID: 19749437
Published date: 2009 Dec
Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Journal of Alzheimer's disease : JAD 18 (4):885-96. PubMed PMID: 19749437
Published date: 2009 Dec
The APOE epsilon4 allele is associated with incident mild cognitive impairment among community-dwelling older persons.
Boyle PA, Buchman AS, Wilson RS, Kelly JF, Bennett DA
Neuroepidemiology 34 (1):43-9. PubMed PMID: 19907191
Published date: 2010
High blood pressure and microinfarcts: a link between vascular risk factors, dementia, and clinical Alzheimer's disease.
Schneider JA
Journal of the American Geriatrics Society 57 (11):2146-7. PubMed PMID: 20121957
Published date: 2009 Nov
A battery of tests for assessing cognitive function in older Latino persons.
Krueger KR, Wilson RS, Bennett DA, Aggarwal NT
Alzheimer disease and associated disorders 23 (4):384-8. PubMed PMID: 19561439
Published date: 2009 Oct-Dec
Kidney function is associated with the rate of cognitive decline in the elderly.
Buchman AS, Tanne D, Boyle PA, Shah RC, Leurgans SE, Bennett DA
Neurology 73 (12):920-7. PubMed PMID: 19657107
Published date: 2009 Sep 22
The neuropathology of older persons with and without dementia from community versus clinic cohorts.
Schneider JA, Aggarwal NT, Barnes L, Boyle P, Bennett DA
Journal of Alzheimer's disease : JAD 18 (3):691-701. PubMed PMID: 19749406
Published date: 2009
Race differences in emotional adaptation of family caregivers.
Skarupski KA, McCann JJ, Bienias JL, Evans DA
Aging & mental health 13 (5):715-24. PubMed PMID: 19882410
Published date: 2009 Sep
The neuropathology of probable Alzheimer disease and mild cognitive impairment.
Schneider JA, Arvanitakis Z, Leurgans SE, Bennett DA
Annals of neurology 66 (2):200-8. PubMed PMID: 19743450
Published date: 2009 Aug
Brain sterol dysregulation in sporadic AD and MCI: relationship to heme oxygenase-1.
Hascalovici JR, Vaya J, Khatib S, Holcroft CA, Zukor H, Song W, Arvanitakis Z, Bennett DA, Schipper HM
Journal of neurochemistry 110 (4):1241-53. PubMed PMID: 19522732
Published date: 2009 Jun 9
NSAID exposure and risk of Alzheimer disease: is timing everything?
Bennett DA, Whitmer RA
Neurology 72 (22):1884-5. PubMed PMID: 19386996
Published date: 2009 Jun 2
Purpose in life is associated with mortality among community-dwelling older persons.
Boyle PA, Barnes LL, Buchman AS, Bennett DA
Psychosomatic medicine 71 (5):574-9. PubMed PMID: 19414613
Published date: 2009 Jun
Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.
Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST
Archives of neurology 66 (5):646-51. PubMed PMID: 19433665
Published date: 2009 May
Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.
Ikonomovic MD, Wecker L, Abrahamson EE, Wuu J, Counts SE, Ginsberg SD, Mufson EJ, Dekosky ST
Archives of neurology 66 (5):646-51. PubMed PMID: 19433665
Published date: 2009 May
Improving dementia care in assisted living residences: addressing staff reactions to training.
Teri L, McKenzie GL, LaFazia D, Farran CJ, Beck C, Huda P, van Leynseele J, Pike KC
Geriatric nursing (New York, N.Y.) 30 (3):153-63. PubMed PMID: 19520226
Published date: 2009 May-Jun
Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles.
Bennett DA, De Jager PL, Leurgans SE, Schneider JA
Neurology 72 (17):1495-503. PubMed PMID: 19398704
Published date: 2009 Apr 28
Evidence of angiogenic vessels in Alzheimer's disease.
Desai BS, Schneider JA, Li JL, Carvey PM, Hendey B
Journal of neural transmission (Vienna, Austria : 1996) 116 (5):587-97. PubMed PMID: 19370387
Published date: 2009 Apr 16
Genetic control of human brain transcript expression in Alzheimer disease.
Webster JA, Gibbs JR, Clarke J, Ray M, Zhang W, Holmans P, Rohrer K, Zhao A, Marlowe L, Kaleem M, McCorquodale DS, Cuello C, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Heward CB, Reim
American journal of human genetics 84 (4):445-58. PubMed PMID: 19361613
Published date: 2009 Apr
Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation.
Dawe RJ, Bennett DA, Schneider JA, Vasireddi SK, Arfanakis K
Magnetic resonance in medicine 61 (4):810-8. PubMed PMID: 19189294
Published date: 2009 Apr
The Alzheimer's Disease Centers' Uniform Data Set (UDS): the neuropsychologic test battery.
Weintraub S, Salmon D, Mercaldo N, Ferris S, Graff-Radford NR, Chui H, Cummings J, DeCarli C, Foster NL, Galasko D, Peskind E, Dietrich W, Beekly DL, Kukull WA, Morris JC
Alzheimer disease and associated disorders 23 (2):91-101. PubMed PMID: 19474567
Published date: 2009 Apr-Jun
The Spanish translation and adaptation of the Uniform Data Set of the National Institute on Aging Alzheimer's Disease Centers.
Acevedo A, Krueger KR, Navarro E, Ortiz F, Manly JJ, Padilla-Vélez MM, Weintraub S, López OL, Mungas D
Alzheimer disease and associated disorders 23 (2):102-9. PubMed PMID: 19474568
Published date: 2009 Apr-Jun
Visuoperceptual repetition priming and progression of parkinsonian signs in aging.
Fleischman DA, Buchman AS, Bienias JL, Bennett DA
Neurobiology of aging 30 (3):441-9. PubMed PMID: 17709154
Published date: 2009 Mar
Early risk assessment for Alzheimer's disease.
Carrillo MC, Blackwell A, Hampel H, Lindborg J, Sperling R, Schenk D, Sevigny JJ, Ferris S, Bennett DA, Craft S, Hsu T, Klunk W
Alzheimer's & dementia : the journal of the Alzheimer's Association 5 (2):182-96. PubMed PMID: 19328456
Published date: 2009 Mar
Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease.
Julien C, Tremblay C, Emond V, Lebbadi M, Salem N, Bennett DA, Calon F
Journal of neuropathology and experimental neurology 68 (1):48-58. PubMed PMID: 19104446
Published date: 2009 Jan
Plasma urate and progression of mild cognitive impairment.
Irizarry MC, Raman R, Schwarzschild MA, Becerra LM, Thomas RG, Peterson RC, Ascherio A, Aisen PS
Neuro-degenerative diseases 6 (1-2):23-8. PubMed PMID: 19066433
Published date: 2009
Developing a Measurement Strategy for Assessing Family Caregiver Skills: Conceptual Issues.
Farran CJ, McCann JJ, Fogg LG, Etkin CD
Alzheimer's care today 10 (3):129-139. PubMed PMID: 20179779
Published date: 2009
Changes in parahippocampal white matter integrity in amnestic mild cognitive impairment: a diffusion tensor imaging study.
Rogalski EJ, Murphy CM, deToledo-Morrell L, Shah RC, Moseley ME, Bammer R, Stebbins GT
Behavioural neurology 21 (1):51-61. PubMed PMID: 19847045
Published date: 2009
Repetition priming and change in functional ability in older persons without dementia.
Fleischman DA, Bienias JL, Bennett DA
Neuropsychology 23 (1):98-104. PubMed PMID: 19210037
Published date: 2009 Jan
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.
O'Connor T, Sadleir KR, Maus E, Velliquette RA, Zhao J, Cole SL, Eimer WA, Hitt B, Bembinster LA, Lammich S, Lichtenthaler SF, Hébert SS, De Strooper B, Haass C, Bennett DA, Vassar R
Neuron 60 (6):988-1009. PubMed PMID: 19109907
Published date: 2008 Dec 26
Cognitive health in indigenous peoples.
Bennett DA
Neurology 71 (19):1466-7. PubMed PMID: 18799784
Published date: 2008 Nov 4
Caspase-3 is enriched in postsynaptic densities and increased in Alzheimer's disease.
Louneva N, Cohen JW, Han LY, Talbot K, Wilson RS, Bennett DA, Trojanowski JQ, Arnold SE
The American journal of pathology 173 (5):1488-95. PubMed PMID: 18818379
Published date: 2008 Nov
Change in direct measures of physical performance among persons with Alzheimer's disease.
Hebert LE, Scherr PA, McCann JJ, Bienias JL, Evans DA
Aging & mental health 12 (6):729-34. PubMed PMID: 19023724
Published date: 2008 Nov
Analyses of the National Institute on Aging Late-Onset Alzheimer's Disease Family Study: implication of additional loci.
Lee JH, Cheng R, Graff-Radford N, Foroud T, Mayeux R
Archives of neurology 65 (11):1518-26. PubMed PMID: 19001172
Published date: 2008 Nov
High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial.
Aisen PS, Schneider LS, Sano M, Diaz-Arrastia R, van Dyck CH, Weiner MF, Bottiglieri T, Jin S, Stokes KT, Thomas RG, Thal LJ
JAMA 300 (15):1774-83. PubMed PMID: 18854539
Published date: 2008 Oct 15
Rate of entorhinal and hippocampal atrophy in incipient and mild AD: relation to memory function.
Stoub TR, Rogalski EJ, Leurgans S, Bennett DA, Detoledo-Morrell L
Neurobiology of aging 31 (7):1089-98. PubMed PMID: 18809228
Published date: 2008 Sep 20
Evidence for an association between KIBRA and late-onset Alzheimer's disease.
Corneveaux JJ, Liang WS, Reiman EM, Webster JA, Myers AJ, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Craig DW, Coon KD, Dunckley T, Bandy D, Lee W, Chen K, Beach TG, Mastroeni D, Grover A, Ravid R, Sando SB, Aasly JO, Heun R, Jessen F, Kölsch
Neurobiology of aging 31 (6):901-9. PubMed PMID: 18789830
Published date: 2008 Sep 11
Physical frailty in older persons is associated with Alzheimer disease pathology.
Buchman AS, Schneider JA, Leurgans S, Bennett DA
Neurology 71 (7):499-504. PubMed PMID: 18695161
Published date: 2008 Aug 12
Interpreting the clinical significance of capacity scores for informed consent in Alzheimer disease clinical trials.
Karlawish J, Kim SY, Knopman D, van Dyck CH, James BD, Marson D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 16 (7):568-74. PubMed PMID: 18556397
Published date: 2008 Jul
Relation of NSAIDs to incident AD, change in cognitive function, and AD pathology.
Arvanitakis Z, Grodstein F, Bienias JL, Schneider JA, Wilson RS, Kelly JF, Evans DA, Bennett DA
Neurology 70 (23):2219-25. PubMed PMID: 18519870
Published date: 2008 Jun 3
Galanin in Alzheimer's disease: neuroinhibitory or neuroprotective?
Counts SE, Perez SE, Mufson EJ
Cellular and molecular life sciences : CMLS 65 (12):1842-53. PubMed PMID: 18500641
Published date: 2008 Jun
Statins, incident Alzheimer disease, change in cognitive function, and neuropathology.
Arvanitakis Z, Schneider JA, Wilson RS, Bienias JL, Kelly JF, Evans DA, Bennett DA
Neurology 70 (19 Pt 2):1795-802. PubMed PMID: 18199831
Published date: 2008 May 6
Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease.
Zhu H, Taylor JW, Bennett DA, Younkin SG, Estus S
Neurobiology of aging 29 (5):793-4. PubMed PMID: 17175070
Published date: 2008 May
A lifestyle physical activity intervention for caregivers of persons with Alzheimer's disease.
Farran CJ, Staffileno BA, Gilley DW, McCann JJ, Yan Li, Castro CM, King AC
American journal of Alzheimer's disease and other dementias 23 (2):132-42. PubMed PMID: 18174315
Published date: 2008 Apr-May
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE
Nature neuroscience 11 (4):476-87. PubMed PMID: 18344994
Published date: 2008 Apr
Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.
Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, Estus S
Human molecular genetics 17 (7):929-35. PubMed PMID: 18065781
Published date: 2008 Apr 1
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Papadia S, Soriano FX, Léveillé F, Martel MA, Dakin KA, Hansen HH, Kaindl A, Sifringer M, Fowler J, Stefovska V, McKenzie G, Craigon M, Corriveau R, Ghazal P, Horsburgh K, Yankner BA, Wyllie DJ, Ikonomidou C, Hardingham GE
Nature neuroscience 11 (4):476-87. PubMed PMID: 18344994
Published date: 2008 Apr
Change in depressive symptoms during the prodromal phase of Alzheimer disease.
Wilson RS, Arnold SE, Beck TL, Bienias JL, Bennett DA
Archives of general psychiatry 65 (4):439-45. PubMed PMID: 18391132
Published date: 2008 Apr
The views of Alzheimer disease patients and their study partners on proxy consent for clinical trial enrollment.
Karlawish J, Kim SY, Knopman D, van Dyck CH, James BD, Marson D
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 16 (3):240-7. PubMed PMID: 18310554
Published date: 2008 Mar
Cognitive performance correlates with cortical isopeptide immunoreactivity as well as Alzheimer type pathology.
Wang DS, Uchikado H, Bennett DA, Schneider JA, Mufson EJ, Wu J, Dickson DW
Journal of Alzheimer's disease : JAD 13 (1):53-66. PubMed PMID: 18334757
Published date: 2008 Feb
Levels of estrogen receptors alpha and beta in frontal cortex of patients with Alzheimer's disease: relationship to Mini-Mental State Examination scores.
Kelly JF, Bienias JL, Shah A, Meeke KA, Schneider JA, Soriano E, Bennett DA
Current Alzheimer research 5 (1):45-51. PubMed PMID: 18288931
Published date: 2008 Feb
Use of home-based formal services by adult day care clients with Alzheimer's disease.
Skarupski KA, McCann JJ, Bienias JL, Wolinsky FD, Aggarwal NT, Evans DA
Home health care services quarterly 27 (3):217-39. PubMed PMID: 19042238
Published date: 2008
Transcriptome-wide assessment of human brain and lymphocyte senescence.
Hong MG, Myers AJ, Magnusson PK, Prince JA
PloS one 3 (8):e3024. PubMed PMID: 18714388
Published date: 2008
fMRI activation changes during successful episodic memory encoding and recognition in amnestic mild cognitive impairment relative to cognitively healthy older adults.
Trivedi MA, Murphy CM, Goetz C, Shah RC, Gabrieli JD, Whitfield-Gabrieli S, Turner DA, Stebbins GT
Dementia and geriatric cognitive disorders 26 (2):123-37. PubMed PMID: 18663302
Published date: 2008
Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Neuro-degenerative diseases 5 (3-4):228-31. PubMed PMID: 18322398
Published date: 2008
Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease.
Counts SE, He B, Che S, Ginsberg SD, Mufson EJ
Neuro-degenerative diseases 5 (3-4):228-31. PubMed PMID: 18322398
Published date: 2008
Plaque complement activation and cognitive loss in Alzheimer's disease.
Loeffler DA, Camp DM, Bennett DA
Journal of neuroinflammation. PubMed PMID: 18334032
Published date: 2008
Mixed brain pathologies account for most dementia cases in community-dwelling older persons.
Schneider JA, Arvanitakis Z, Bang W, Bennett DA
Neurology 69 (24):2197-204. PubMed PMID: 17568013
Published date: 2007 Dec 11
Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.
Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, Mufson EJ
Archives of neurology 64 (12):1771-6. PubMed PMID: 18071042
Published date: 2007 Dec
Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.
Counts SE, He B, Che S, Ikonomovic MD, DeKosky ST, Ginsberg SD, Mufson EJ
Archives of neurology 64 (12):1771-6. PubMed PMID: 18071042
Published date: 2007 Dec
Biochemical characterization of Abeta and tau pathologies in mild cognitive impairment and Alzheimer's disease.
Tremblay C, Pilote M, Phivilay A, Emond V, Bennett DA, Calon F
Journal of Alzheimer's disease : JAD 12 (4):377-90. PubMed PMID: 18198424
Published date: 2007 Dec
Neuronal LR11/sorLA expression is reduced in mild cognitive impairment.
Sager KL, Wuu J, Leurgans SE, Rees HD, Gearing M, Mufson EJ, Levey AI, Lah JJ
Annals of neurology 62 (6):640-7. PubMed PMID: 17721864
Published date: 2007 Dec
Efficacy of behavioral interventions for dementia caregivers.
Farran CJ, Gilley DW, McCann JJ, Bienias JL, Lindeman DA, Evans DA
Western journal of nursing research 29 (8):944-60. PubMed PMID: 17596639
Published date: 2007 Dec
Mild cognitive impairment.
Aggarwal NT
Panminerva medica 49 (4):183-9. PubMed PMID: 18091670
Published date: 2007 Dec
A survey of genetic human cortical gene expression.
Myers AJ, Gibbs JR, Webster JA, Rohrer K, Zhao A, Marlowe L, Kaleem M, Leung D, Bryden L, Nath P, Zismann VL, Joshipura K, Huentelman MJ, Hu-Lince D, Coon KD, Craig DW, Pearson JV, Holmans P, Heward CB, Reiman EM, Stephan D, Hardy J
Nature genetics 39 (12):1494-9. PubMed PMID: 17982457
Published date: 2007 Dec
Paradoxical upregulation of glutamatergic presynaptic boutons during mild cognitive impairment.
Bell KF, Bennett DA, Cuello AC
The Journal of neuroscience : the official journal of the Society for Neuroscience 27 (40):10810-7. PubMed PMID: 17913914
Published date: 2007 Oct 3
Repetition priming in aging and Alzheimer's disease: an integrative review and future directions.
Fleischman DA
Cortex; a journal devoted to the study of the nervous system and behavior 43 (7):889-97. PubMed PMID: 17941347
Published date: 2007 Oct
Conscientiousness and the incidence of Alzheimer disease and mild cognitive impairment.
Wilson RS, Schneider JA, Arnold SE, Bienias JL, Bennett DA
Archives of general psychiatry 64 (10):1204-12. PubMed PMID: 17909133
Published date: 2007 Oct
Superior frontal cortex cholinergic axon density in mild cognitive impairment and early Alzheimer disease.
Ikonomovic MD, Abrahamson EE, Isanski BA, Wuu J, Mufson EJ, DeKosky ST
Archives of neurology 64 (9):1312-7. PubMed PMID: 17846271
Published date: 2007 Sep
Estimation of the mediation effect with a binary mediator.
Li Y, Schneider JA, Bennett DA
Statistics in medicine 26 (18):3398-414. PubMed PMID: 17066450
Published date: 2007 Aug 15
Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons.
Schneider JA, Boyle PA, Arvanitakis Z, Bienias JL, Bennett DA
Annals of neurology 62 (1):59-66. PubMed PMID: 17503514
Published date: 2007 Jul
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
Cairns NJ, Neumann M, Bigio EH, Holm IE, Troost D, Hatanpaa KJ, Foong C, White CL, Schneider JA, Kretzschmar HA, Carter D, Taylor-Reinwald L, Paulsmeyer K, Strider J, Gitcho M, Goate AM, Morris JC, Mishra M, Kwong LK, Stieber A, Xu Y, Forman MS, Troj
The American journal of pathology 171 (1):227-40. PubMed PMID: 17591968
Published date: 2007 Jul
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration.
Cairns NJ, Bigio EH, Mackenzie IR, Neumann M, Lee VM, Hatanpaa KJ, White CL, Schneider JA, Grinberg LT, Halliday G, Duyckaerts C, Lowe JS, Holm IE, Tolnay M, Okamoto K, Yokoo H, Murayama S, Woulfe J, Munoz DG, Dickson DW, Ince PG, Trojanowski JQ, Man
Acta neuropathologica 114 (1):5-22. PubMed PMID: 17579875
Published date: 2007 Jul
Chronic distress and incidence of mild cognitive impairment.
Wilson RS, Schneider JA, Boyle PA, Arnold SE, Tang Y, Bennett DA
Neurology 68 (24):2085-92. PubMed PMID: 17562829
Published date: 2007 Jun 12
GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers.
Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, Joshipura KD, Pearson JV, Hu-Lince D, Huentelman MJ, Craig DW, Coon KD, Liang WS, Herbert RH, Beach T, Rohrer KC, Zhao AS, Leung D, Bryden L, Marlowe L, Kaleem M, Mastroeni D, Grover A
Neuron 54 (5):713-20. PubMed PMID: 17553421
Published date: 2007 Jun 7
Nursing home placement, day care use, and cognitive decline in Alzheimer's disease.
Wilson RS, McCann JJ, Li Y, Aggarwal NT, Gilley DW, Evans DA
The American journal of psychiatry 164 (6):910-5. PubMed PMID: 17541050
Published date: 2007 Jun
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment.
Scheff SW, Price DA, Schmitt FA, DeKosky ST, Mufson EJ
Neurology 68 (18):1501-8. PubMed PMID: 17470753
Published date: 2007 May 1
Brain erythropoietin receptor expression in Alzheimer disease and mild cognitive impairment.
Assaraf MI, Diaz Z, Liberman A, Miller WH, Arvanitakis Z, Li Y, Bennett DA, Schipper HM
Journal of neuropathology and experimental neurology 66 (5):389-98. PubMed PMID: 17483696
Published date: 2007 May
Quetiapine for agitation or psychosis in patients with dementia and parkinsonism.
Kurlan R, Cummings J, Raman R, Thal L
Neurology 68 (17):1356-63. PubMed PMID: 17452579
Published date: 2007 Apr 24
Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.
Berger Z, Roder H, Hanna A, Carlson A, Rangachari V, Yue M, Wszolek Z, Ashe K, Knight J, Dickson D, Andorfer C, Rosenberry TL, Lewis J, Hutton M, Janus C
The Journal of neuroscience : the official journal of the Society for Neuroscience 27 (14):3650-62. PubMed PMID: 17409229
Published date: 2007 Apr 4
Activation of caspase-6 in aging and mild cognitive impairment.
Albrecht S, Bourdeau M, Bennett D, Mufson EJ, Bhattacharjee M, LeBlanc AC
The American journal of pathology 170 (4):1200-9. PubMed PMID: 17392160
Published date: 2007 Apr
Cortical biochemistry in MCI and Alzheimer disease: lack of correlation with clinical diagnosis.
Forman MS, Mufson EJ, Leurgans S, Pratico D, Joyce S, Leight S, Lee VM, Trojanowski JQ
Neurology 68 (10):757-63. PubMed PMID: 17339583
Published date: 2007 Mar 6
The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts.
Myers AJ, Pittman AM, Zhao AS, Rohrer K, Kaleem M, Marlowe L, Lees A, Leung D, McKeith IG, Perry RH, Morris CM, Trojanowski JQ, Clark C, Karlawish J, Arnold S, Forman MS, Van Deerlin V, de Silva R, Hardy J
Neurobiology of disease 25 (3):561-70. PubMed PMID: 17174556
Published date: 2007 Mar
The significance of Pin1 in the development of Alzheimer's disease.
Wang S, Simon BP, Bennett DA, Schneider JA, Malter JS, Wang DS
Journal of Alzheimer's disease : JAD 11 (1):13-23. PubMed PMID: 17361031
Published date: 2007 Mar
Confounding in the Estimation of Mediation Effects.
Li Y, Bienias JL, Bennett DA
Computational statistics & data analysis 51 (6):3173-3186. PubMed PMID: 17940582
Published date: 2007 Mar 1
Vascular dementia: emerging trends.
Aggarwal NT, Decarli C
Seminars in neurology 27 (1):66-77. PubMed PMID: 17226743
Published date: 2007 Feb
Grip strength and the risk of incident Alzheimer's disease.
Buchman AS, Wilson RS, Boyle PA, Bienias JL, Bennett DA
Neuroepidemiology 29 (1-2):66-73. PubMed PMID: 17925596
Published date: 2007
Editorial comment on 'Prevalence of dementia in the United States: the aging, demographics, and memory study' by Plassman et al.
Bennett DA
Neuroepidemiology 29 (1-2):133-5. PubMed PMID: 17975327
Published date: 2007
Chronic distress, age-related neuropathology, and late-life dementia.
Wilson RS, Arnold SE, Schneider JA, Li Y, Bennett DA
Psychosomatic medicine 69 (1):47-53. PubMed PMID: 17244848
Published date: 2007 Jan
Body mass index in older persons is associated with Alzheimer disease pathology.
Buchman AS, Schneider JA, Wilson RS, Bienias JL, Bennett DA
Neurology 67 (11):1949-54. PubMed PMID: 17159099
Published date: 2006 Dec 12
Diabetes is related to cerebral infarction but not to AD pathology in older persons.
Arvanitakis Z, Schneider JA, Wilson RS, Li Y, Arnold SE, Wang Z, Bennett DA
Neurology 67 (11):1960-5. PubMed PMID: 17159101
Published date: 2006 Dec 12
Cognitive decline in old age: separating retest effects from the effects of growing older.
Wilson RS, Li Y, Bienias JL, Bennett DA
Psychology and aging 21 (4):774-89. PubMed PMID: 17201497
Published date: 2006 Dec
Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease.
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Bennett DA
Archives of neurology 63 (12):1763-9. PubMed PMID: 17172617
Published date: 2006 Dec
Association of daytime napping and Parkinsonian signs in Alzheimer's disease.
Park M, Comella CL, Leurgans SE, Fan W, Wilson RS, Bennett DA
Sleep medicine 7 (8):614-8. PubMed PMID: 17023213
Published date: 2006 Dec
The amyloid pathology progresses in a neurotransmitter-specific manner.
Bell KF, Ducatenzeiler A, Ribeiro-da-Silva A, Duff K, Bennett DA, Cuello AC
Neurobiology of aging 27 (11):1644-57. PubMed PMID: 16271419
Published date: 2006 Nov
ADCS Prevention Instrument Project: overview and initial results.
Ferris SH, Aisen PS, Cummings J, Galasko D, Salmon DP, Schneider L, Sano M, Whitehouse PJ, Edland S, Thal LJ
Alzheimer disease and associated disorders 20 (4 Suppl 3):S109-23. PubMed PMID: 17135805
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: behavioral measures in primary prevention trials.
Cummings JL, Raman R, Ernstrom K, Salmon D, Ferris SH
Alzheimer disease and associated disorders 20 (4 Suppl 3):S147-51. PubMed PMID: 17135808
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: development of a brief verbal memory test for primary prevention clinical trials.
Salmon DP, Cummings JL, Jin S, Sano M, Sperling RA, Zamrini E, Petersen RC, Edland SD, Thal LJ, Ferris SH
Alzheimer disease and associated disorders 20 (4 Suppl 3):S139-46. PubMed PMID: 17135807
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: pharmacoeconomics: assessing health-related resource use among healthy elderly.
Sano M, Zhu CW, Whitehouse PJ, Edland S, Jin S, Ernstrom K, Thomas RG, Thal LJ, Ferris SH
Alzheimer disease and associated disorders 20 (4 Suppl 3):S191-202. PubMed PMID: 17135812
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: assessment of instrumental activities of daily living for community-dwelling elderly individuals in dementia prevention clinical trials.
Galasko D, Bennett DA, Sano M, Marson D, Kaye J, Edland SD
Alzheimer disease and associated disorders 20 (4 Suppl 3):S152-69. PubMed PMID: 17135809
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: the Mail-In Cognitive Function Screening Instrument (MCFSI).
Walsh SP, Raman R, Jones KB, Aisen PS
Alzheimer disease and associated disorders 20 (4 Suppl 3):S170-8. PubMed PMID: 17135810
Published date: 2006 Oct-Dec
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.
Scheff SW, Price DA, Schmitt FA, Mufson EJ
Neurobiology of aging 27 (10):1372-84. PubMed PMID: 16289476
Published date: 2006 Oct
Hippocampal synaptic loss in early Alzheimer's disease and mild cognitive impairment.
Scheff SW, Price DA, Schmitt FA, Mufson EJ
Neurobiology of aging 27 (10):1372-84. PubMed PMID: 16289476
Published date: 2006 Oct
ADCS Prevention Instrument Project: pilot testing of a book club as a psychosocial intervention and recruitment and retention strategy.
Whitehouse PJ, Rajcan JL, Sami SA, Patterson MB, Smyth KA, Edland SD, George DR
Alzheimer disease and associated disorders 20 (4 Suppl 3):S203-8. PubMed PMID: 17135813
Published date: 2006 Oct-Dec
ADCS Prevention Instrument Project: quality of life assessment (QOL).
Patterson MB, Whitehouse PJ, Edland SD, Sami SA, Sano M, Smyth K, Weiner MF
Alzheimer disease and associated disorders 20 (4 Suppl 3):S179-90. PubMed PMID: 17135811
Published date: 2006 Oct-Dec
The relation of lifetime cognitive activity and lifetime access to resources to late-life cognitive function in older African Americans.
Barnes LL, Wilson RS, de Leon CF, Bennett DA
Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition 13 (3-4):516-28. PubMed PMID: 16887787
Published date: 2006 Sep-Dec
Blood pressure and lower limb function in older persons.
Shah RC, Wilson RS, Bienias JL, Arvanitakis Z, Evans DA, Bennett DA
The journals of gerontology. Series A, Biological sciences and medical sciences 61 (8):839-43. PubMed PMID: 16912102
Published date: 2006 Aug
Early involvement of small inhibitory cortical interneurons in Alzheimer's disease.
Koliatsos VE, Kecojevic A, Troncoso JC, Gastard MC, Bennett DA, Schneider JA
Acta neuropathologica 112 (2):147-62. PubMed PMID: 16758165
Published date: 2006 Aug
Reno-cerebrovascular disease? The incognito kidney in cognition and stroke.
Monk RD, Bennett DA
Neurology 67 (2):196-8. PubMed PMID: 16864806
Published date: 2006 Jul 25
Diabetes mellitus, dementia, and cognitive function in older persons.
Arvanitakis Z, Wilson RS, Bennett DA
The journal of nutrition, health & aging 10 (4):287-91. PubMed PMID: 16886098
Published date: 2006 Jul-Aug
Single cell gene expression profiling in Alzheimer's disease.
Ginsberg SD, Che S, Counts SE, Mufson EJ
NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics 3 (3):302-18. PubMed PMID: 16815214
Published date: 2006 Jul
Postmortem indices linking risk factors to cognition: results from the Religious Order Study and the Memory and Aging Project.
Bennett DA
Alzheimer disease and associated disorders 20 (3 Suppl 2):S63-8. PubMed PMID: 16917198
Published date: 2006 Jul-Sep
Personality and incident disability in older persons.
Krueger KR, Wilson RS, Shah RC, Tang Y, Bennett DA
Age and ageing 35 (4):428-33. PubMed PMID: 16788082
Published date: 2006 Jul
Hippocampal disconnection contributes to memory dysfunction in individuals at risk for Alzheimer's disease.
Stoub TR, deToledo-Morrell L, Stebbins GT, Leurgans S, Bennett DA, Shah RC
Proceedings of the National Academy of Sciences of the United States of America 103 (26):10041-5. PubMed PMID: 16785436
Published date: 2006 Jun 27
Neuropathology of older persons without cognitive impairment from two community-based studies.
Bennett DA, Schneider JA, Arvanitakis Z, Kelly JF, Aggarwal NT, Shah RC, Wilson RS
Neurology 66 (12):1837-44. PubMed PMID: 16801647
Published date: 2006 Jun 27
Differential expression of synaptic proteins in the frontal and temporal cortex of elderly subjects with mild cognitive impairment.
Counts SE, Nadeem M, Lad SP, Wuu J, Mufson EJ
Journal of neuropathology and experimental neurology 65 (6):592-601. PubMed PMID: 16783169
Published date: 2006 Jun
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, Bennett DA, Leurgans S, Turner DA, Stebbins GT
Neurobiology of aging 27 (5):663-72. PubMed PMID: 16005548
Published date: 2006 May
Secular trends in stroke incidence and survival, and the occurrence of dementia.
Bennett DA
Stroke 37 (5):1144-5. PubMed PMID: 16601209
Published date: 2006 May
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study.
Medina D, DeToledo-Morrell L, Urresta F, Gabrieli JD, Moseley M, Fleischman D, Bennett DA, Leurgans S, Turner DA, Stebbins GT
Neurobiology of aging 27 (5):663-72. PubMed PMID: 16005548
Published date: 2006 May
Cognitive decline and survival in Alzheimer's disease.
Wilson RS, Li Y, Aggarwal NT, McCann JJ, Gilley DW, Bienias JL, Barnes LL, Evans DA
International journal of geriatric psychiatry 21 (4):356-62. PubMed PMID: 16534773
Published date: 2006 Apr
Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.
Counts SE, Chen EY, Che S, Ikonomovic MD, Wuu J, Ginsberg SD, Dekosky ST, Mufson EJ
Dementia and geriatric cognitive disorders 21 (4):205-14. PubMed PMID: 16410678
Published date: 2006
Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease.
Ginsberg SD, Che S, Wuu J, Counts SE, Mufson EJ
Journal of neurochemistry 97 (2):475-87. PubMed PMID: 16539663
Published date: 2006 Apr
Cognitive decline and survival in Alzheimer's disease.
Wilson RS, Li Y, Aggarwal NT, McCann JJ, Gilley DW, Bienias JL, Barnes LL, Evans DA
International journal of geriatric psychiatry 21 (4):356-62. PubMed PMID: 16534773
Published date: 2006 Apr
Down regulation of trk but not p75NTR gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease.
Ginsberg SD, Che S, Wuu J, Counts SE, Mufson EJ
Journal of neurochemistry 97 (2):475-87. PubMed PMID: 16539663
Published date: 2006 Apr
Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.
Counts SE, Chen EY, Che S, Ikonomovic MD, Wuu J, Ginsberg SD, Dekosky ST, Mufson EJ
Dementia and geriatric cognitive disorders 21 (4):205-14. PubMed PMID: 16410678
Published date: 2006
Cognitive leisure activities, but not watching TV, for future brain benefits.
Rundek T, Bennett DA
Neurology 66 (6):794-5. PubMed PMID: 16567692
Published date: 2006 Mar 28
Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus.
Dubelaar EJ, Mufson EJ, ter Meulen WG, Van Heerikhuize JJ, Verwer RW, Swaab DF
Journal of neuropathology and experimental neurology 65 (3):257-66. PubMed PMID: 16651887
Published date: 2006 Mar
Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Che S, Counts SE, Mufson EJ
Journal of neurochemistry 96 (5):1401-8. PubMed PMID: 16478530
Published date: 2006 Mar
Shift in the ratio of three-repeat tau and four-repeat tau mRNAs in individual cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.
Ginsberg SD, Che S, Counts SE, Mufson EJ
Journal of neurochemistry 96 (5):1401-8. PubMed PMID: 16478530
Published date: 2006 Mar
Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus.
Dubelaar EJ, Mufson EJ, ter Meulen WG, Van Heerikhuize JJ, Verwer RW, Swaab DF
Journal of neuropathology and experimental neurology 65 (3):257-66. PubMed PMID: 16651887
Published date: 2006 Mar
Glial heme oxygenase-1 expression in Alzheimer disease and mild cognitive impairment.
Schipper HM, Bennett DA, Liberman A, Bienias JL, Schneider JA, Kelly J, Arvanitakis Z
Neurobiology of aging 27 (2):252-61. PubMed PMID: 16399210
Published date: 2006 Feb
Hallucinations, cognitive decline, and death in Alzheimer's disease.
Wilson RS, Tang Y, Aggarwal NT, Gilley DW, McCann JJ, Bienias JL, Evans DA
Neuroepidemiology 26 (2):68-75. PubMed PMID: 16352909
Published date: 2006
Relation of blood pressure to risk of incident Alzheimer's disease and change in global cognitive function in older persons.
Shah RC, Wilson RS, Bienias JL, Arvanitakis Z, Evans DA, Bennett DA
Neuroepidemiology 26 (1):30-6. PubMed PMID: 16254451
Published date: 2006
Substantia nigra tangles are related to gait impairment in older persons.
Schneider JA, Li JL, Li Y, Wilson RS, Kordower JH, Bennett DA
Annals of neurology 59 (1):166-73. PubMed PMID: 16374822
Published date: 2006 Jan
Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study.
Bennett DA, Schneider JA, Aggarwal NT, Arvanitakis Z, Shah RC, Kelly JF, Fox JH, Cochran EJ, Arends D, Treinkman AD, Wilson RS
Neuroepidemiology 27 (3):169-76. PubMed PMID: 17035694
Published date: 2006
Parkinsonian signs in subjects with mild cognitive impairment.
Boyle PA, Wilson RS, Aggarwal NT, Arvanitakis Z, Kelly J, Bienias JL, Bennett DA
Neurology 65 (12):1901-6. PubMed PMID: 16380610
Published date: 2005 Dec 27
Change in cognitive function in Alzheimer's disease in African-American and white persons.
Barnes LL, Wilson RS, Li Y, Gilley DW, Bennett DA, Evans DA
Neuroepidemiology 26 (1):16-22. PubMed PMID: 16254449
Published date: 2006
Repetition priming and recognition memory in younger and older persons: temporal stability and performance.
Fleischman DA, Gabrieli JD, Wilson RS, Moro TT, Bennett DA
Neuropsychology 19 (6):750-9. PubMed PMID: 16351350
Published date: 2005 Nov
Hallucinations and mortality in Alzheimer disease.
Wilson RS, Krueger KR, Kamenetsky JM, Tang Y, Gilley DW, Bennett DA, Evans DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 13 (11):984-90. PubMed PMID: 16286442
Published date: 2005 Nov
Neuroticism, extraversion, and mortality in a defined population of older persons.
Wilson RS, Krueger KR, Gu L, Bienias JL, Mendes de Leon CF, Evans DA
Psychosomatic medicine 67 (6):841-5. PubMed PMID: 16314587
Published date: 2005 Nov-Dec
Mild cognitive impairment in different functional domains and incident Alzheimer's disease.
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Bennett DA
Journal of neurology, neurosurgery, and psychiatry 76 (11):1479-84. PubMed PMID: 16227534
Published date: 2005 Nov
Racial differences in the progression of cognitive decline in Alzheimer disease.
Barnes LL, Wilson RS, Li Y, Aggarwal NT, Gilley DW, McCann JJ, Evans DA
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 13 (11):959-67. PubMed PMID: 16286439
Published date: 2005 Nov
Socioeconomic characteristics of the community in childhood and cognition in old age.
Wilson RS, Scherr PA, Bienias JL, Mendes de Leon CF, Everson-Rose SA, Bennett DA, Evans DA
Experimental aging research 31 (4):393-407. PubMed PMID: 16147459
Published date: 2005 Oct-Dec
High-resolution serum proteomic profiling of Alzheimer disease samples reveals disease-specific, carrier-protein-bound mass signatures.
Lopez MF, Mikulskis A, Kuzdzal S, Bennett DA, Kelly J, Golenko E, DiCesare J, Denoyer E, Patton WF, Ediger R, Sapp L, Ziegert T, Lynch C, Kramer S, Whiteley GR, Wall MR, Mannion DP, Della Cioppa G, Rakitan JS, Wolfe GM
Clinical chemistry 51 (10):1946-54. PubMed PMID: 16081505
Published date: 2005 Oct
Education modifies the association of amyloid but not tangles with cognitive function.
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE
Neurology 65 (6):953-5. PubMed PMID: 16186546
Published date: 2005 Sep 27
Change in body mass index and risk of incident Alzheimer disease.
Buchman AS, Wilson RS, Bienias JL, Shah RC, Evans DA, Bennett DA
Neurology 65 (6):892-7. PubMed PMID: 16186530
Published date: 2005 Sep 27
Implicit memory and Alzheimer's disease neuropathology.
Fleischman DA, Wilson RS, Gabrieli JD, Schneider JA, Bienias JL, Bennett DA
Brain : a journal of neurology 128 (Pt 9):2006-15. PubMed PMID: 15975947
Published date: 2005 Sep
Parkinsonian signs and cognitive function in old age.
Fleischman DA, Wilson RS, Bienias JL, Bennett DA
Journal of the International Neuropsychological Society : JINS 11 (5):591-7. PubMed PMID: 16212686
Published date: 2005 Sep
Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people.
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Berry-Kravis E, Arnold SE
Journal of neurology, neurosurgery, and psychiatry 76 (9):1194-9. PubMed PMID: 16107349
Published date: 2005 Sep
Caspase-cleaved tau accumulation in neurodegenerative diseases associated with tau and alpha-synuclein pathology.
Newman J, Rissman RA, Sarsoza F, Kim RC, Dick M, Bennett DA, Cotman CW, Rohn TT, Head E
Acta neuropathologica 110 (2):135-44. PubMed PMID: 15986225
Published date: 2005 Aug
Relationship between Alzheimer's disease clinical stage and Gq/11 in subcellular fractions of frontal cortex.
Kelly JF, Storie K, Skamra C, Bienias J, Beck T, Bennett DA
Journal of neural transmission (Vienna, Austria : 1996) 112 (8):1049-56. PubMed PMID: 15583959
Published date: 2005 Aug
Detailed assessment of activities of daily living in moderate to severe Alzheimer's disease.
Galasko D, Schmitt F, Thomas R, Jin S, Bennett D
Journal of the International Neuropsychological Society : JINS 11 (4):446-53. PubMed PMID: 16209425
Published date: 2005 Jul
Risk of late-onset Alzheimer's disease associated with BDNF C270T polymorphism.
Olin D, MacMurray J, Comings DE
Neuroscience letters 381 (3):275-8. PubMed PMID: 15896483
Published date: 2005 Jun 24
Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease.
Zhu H, Gopalraj RK, Kelly JF, Bennett DA, Estus S
Neuroscience letters 381 (1-2):36-41. PubMed PMID: 15882786
Published date: 2005 Jun 10-17
Sex differences in the clinical manifestations of Alzheimer disease pathology.
Barnes LL, Wilson RS, Bienias JL, Schneider JA, Evans DA, Bennett DA
Archives of general psychiatry 62 (6):685-91. PubMed PMID: 15939846
Published date: 2005 Jun
Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.
Peng S, Wuu J, Mufson EJ, Fahnestock M
Journal of neurochemistry 93 (6):1412-21. PubMed PMID: 15935057
Published date: 2005 Jun
MRI predictors of risk of incident Alzheimer disease: a longitudinal study.
Stoub TR, Bulgakova M, Leurgans S, Bennett DA, Fleischman D, Turner DA, deToledo-Morrell L
Neurology 64 (9):1520-4. PubMed PMID: 15883311
Published date: 2005 May 10
The apolipoprotein E epsilon4 allele increases the odds of chronic cerebral infarction [corrected] detected at autopsy in older persons.
Schneider JA, Bienias JL, Wilson RS, Berry-Kravis E, Evans DA, Bennett DA
Stroke 36 (5):954-9. PubMed PMID: 15774818
Published date: 2005 May
Genetic variation in the brain derived neurotrophic factor gene in Alzheimer's disease.
Bodner SM, Berrettini W, van Deerlin V, Bennett DA, Wilson RS, Trojanowski JQ, Arnold SE
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 134B (1):1-5. PubMed PMID: 15635706
Published date: 2005 Apr 5
Mild cognitive impairment is related to Alzheimer disease pathology and cerebral infarctions.
Bennett DA, Schneider JA, Bienias JL, Evans DA, Wilson RS
Neurology 64 (5):834-41. PubMed PMID: 15753419
Published date: 2005 Mar 8
Reduction of choline acetyltransferase activity in primary visual cortex in mild to moderate Alzheimer's disease.
Ikonomovic MD, Mufson EJ, Wuu J, Bennett DA, DeKosky ST
Archives of neurology 62 (3):425-30. PubMed PMID: 15767507
Published date: 2005 Mar
Gender differences in upper extremity motor performance of older persons.
Buchman AS, Wilson RS, Bienias JL, Bennett DA
Geriatrics & gerontology international 5 (1):59-65. PubMed PMID: 25782068
Published date: 2005 Mar
Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease.
Georganopoulou DG, Chang L, Nam JM, Thaxton CS, Mufson EJ, Klein WL, Mirkin CA
Proceedings of the National Academy of Sciences of the United States of America 102 (7):2273-6. PubMed PMID: 15695586
Published date: 2005 Feb 15
The apolipoprotein E epsilon4 allele and incident Alzheimer's disease in persons with mild cognitive impairment.
Aggarwal NT, Wilson RS, Beck TL, Bienias JL, Berry-Kravis E, Bennett DA
Neurocase 11 (1):3-7. PubMed PMID: 15804918
Published date: 2005 Feb
Proneness to psychological distress and risk of Alzheimer disease in a biracial community.
Wilson RS, Barnes LL, Bennett DA, Li Y, Bienias JL, Mendes de Leon CF, Evans DA
Neurology 64 (2):380-2. PubMed PMID: 15668449
Published date: 2005 Jan 25
Immunization therapy for Alzheimer disease?
Bennett DA, Holtzman DM
Neurology 64 (1):10-2. PubMed PMID: 15642896
Published date: 2005 Jan 11
Genetic association of low density lipoprotein receptor and Alzheimer's disease.
Gopalraj RK, Zhu H, Kelly JF, Mendiondo M, Pulliam JF, Bennett DA, Estus S
Neurobiology of aging 26 (1):1-7. PubMed PMID: 15585340
Published date: 2005 Jan
A longitudinal study of implicit and explicit memory in old persons.
Fleischman DA, Wilson RS, Gabrieli JD, Bienias JL, Bennett DA
Psychology and aging 19 (4):617-25. PubMed PMID: 15584787
Published date: 2004 Dec
MRI-derived entorhinal volume is a good predictor of conversion from MCI to AD.
deToledo-Morrell L, Stoub TR, Bulgakova M, Wilson RS, Bennett DA, Leurgans S, Wuu J, Turner DA
Neurobiology of aging 25 (9):1197-203. PubMed PMID: 15312965
Published date: 2004 Oct
Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.
Counts SE, Nadeem M, Wuu J, Ginsberg SD, Saragovi HU, Mufson EJ
Annals of neurology 56 (4):520-31. PubMed PMID: 15455399
Published date: 2004 Oct
Diabetes mellitus and progression of rigidity and gait disturbance in older persons.
Arvanitakis Z, Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA
Neurology 63 (6):996-1001. PubMed PMID: 15452289
Published date: 2004 Sep 28
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.
Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 24 (36):7895-902. PubMed PMID: 15356202
Published date: 2004 Sep 8
Subregional analysis of GABA(A) receptor subunit mRNAs in the hippocampus of older persons with and without cognitive impairment.
Rissman RA, Bennett DA, Armstrong DM
Journal of chemical neuroanatomy 28 (1-2):17-25. PubMed PMID: 15363487
Published date: 2004 Sep
A longitudinal study of parkinsonism and disability in a community population of older people.
Murray AM, Bennett DA, Mendes de Leon CF, Beckett LA, Evans DA
The journals of gerontology. Series A, Biological sciences and medical sciences 59 (8):864-70. PubMed PMID: 15345740
Published date: 2004 Aug
Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease.
Peng S, Wuu J, Mufson EJ, Fahnestock M
Journal of neuropathology and experimental neurology 63 (6):641-9. PubMed PMID: 15217092
Published date: 2004 Jun
Caring for self while caring for others: the two-track life of coping with Alzheimer's disease.
Farran CJ, Loukissa DA, Lindeman DA, McCann JJ, Bienias JL
Journal of gerontological nursing 30 (5):38-46. PubMed PMID: 15152743
Published date: 2004 May
Personality and mortality in old age.
Wilson RS, Mendes de Leon CF, Bienias JL, Evans DA, Bennett DA
The journals of gerontology. Series B, Psychological sciences and social sciences 59 (3):P110-6. PubMed PMID: 15118013
Published date: 2004 May
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function.
Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA
Archives of neurology 61 (5):661-6. PubMed PMID: 15148141
Published date: 2004 May
Cerebral infarctions and the likelihood of dementia from Alzheimer disease pathology.
Schneider JA, Wilson RS, Bienias JL, Evans DA, Bennett DA
Neurology 62 (7):1148-55. PubMed PMID: 15079015
Published date: 2004 Apr 13
Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function.
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Arnold SE
Archives of neurology 61 (3):378-84. PubMed PMID: 15023815
Published date: 2004 Mar
Cerebral infarctions and the relationship of depression symptoms to level of cognitive functioning in older persons.
Bennett DA, Wilson RS, Schneider JA, Bienias JL, Arnold SE
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 12 (2):211-9. PubMed PMID: 15010350
Published date: 2004 Mar-Apr
Mild cognitive impairment.
Bennett DA
Clinics in geriatric medicine 20 (1):15-25. PubMed PMID: 15062484
Published date: 2004 Feb
Premorbid proneness to distress and episodic memory impairment in Alzheimer's disease.
Wilson RS, Fleischman DA, Myers RA, Bennett DA, Bienias JL, Gilley DW, Evans DA
Journal of neurology, neurosurgery, and psychiatry 75 (2):191-5. PubMed PMID: 14742585
Published date: 2004 Feb
Depressive symptoms and cognitive decline in a community population of older persons.
Wilson RS, Mendes De Leon CF, Bennett DA, Bienias JL, Evans DA
Journal of neurology, neurosurgery, and psychiatry 75 (1):126-9. PubMed PMID: 14707321
Published date: 2004 Jan
Proneness to psychological distress is associated with risk of Alzheimer's disease.
Wilson RS, Evans DA, Bienias JL, Mendes de Leon CF, Schneider JA, Bennett DA
Neurology 61 (11):1479-85. PubMed PMID: 14663028
Published date: 2003 Dec 9
Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.
Mufson EJ, Ginsberg SD, Ikonomovic MD, DeKosky ST
Journal of chemical neuroanatomy 26 (4):233-42. PubMed PMID: 14729126
Published date: 2003 Dec
Rate of cognitive decline and mortality in Alzheimer's disease.
Hui JS, Wilson RS, Bennett DA, Bienias JL, Gilley DW, Evans DA
Neurology 61 (10):1356-61. PubMed PMID: 14638955
Published date: 2003 Nov 25
Negative affect and mortality in older persons.
Wilson RS, Bienias JL, Mendes de Leon CF, Evans DA, Bennett DA
American journal of epidemiology 158 (9):827-35. PubMed PMID: 14585760
Published date: 2003 Nov 1
Depressive symptoms, clinical AD, and cortical plaques and tangles in older persons.
Wilson RS, Schneider JA, Bienias JL, Arnold SE, Evans DA, Bennett DA
Neurology 61 (8):1102-7. PubMed PMID: 14581672
Published date: 2003 Oct 28
Alzheimer's disease caregiving information and skills. Part I: care recipient issues and concerns.
Farran CJ, Loukissa D, Perraud S, Paun O
Research in nursing & health 26 (5):366-75. PubMed PMID: 14579257
Published date: 2003 Oct
Cognitive activity and cognitive decline in a biracial community population.
Wilson RS, Bennett DA, Bienias JL, Mendes de Leon CF, Morris MC, Evans DA
Neurology 61 (6):812-6. PubMed PMID: 14504326
Published date: 2003 Sep 23
Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.
Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, DeKosky ST
Archives of neurology 60 (8):1143-8. PubMed PMID: 12925373
Published date: 2003 Aug
Alzheimer disease in the US population: prevalence estimates using the 2000 census.
Hebert LE, Scherr PA, Bienias JL, Bennett DA, Evans DA
Archives of neurology 60 (8):1119-22. PubMed PMID: 12925369
Published date: 2003 Aug
Preservation of brain nerve growth factor in mild cognitive impairment and Alzheimer disease.
Mufson EJ, Ikonomovic MD, Styren SD, Counts SE, Wuu J, Leurgans S, Bennett DA, Cochran EJ, DeKosky ST
Archives of neurology 60 (8):1143-8. PubMed PMID: 12925373
Published date: 2003 Aug
Assessment of lifetime participation in cognitively stimulating activities.
Wilson R, Barnes L, Bennett D
Journal of clinical and experimental neuropsychology 25 (5):634-42. PubMed PMID: 12815501
Published date: 2003 Aug
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease.
Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Wilson RS, Aggarwal N, Schneider J
Archives of neurology 60 (7):940-6. PubMed PMID: 12873849
Published date: 2003 Jul
Education modifies the relation of AD pathology to level of cognitive function in older persons.
Bennett DA, Wilson RS, Schneider JA, Evans DA, Mendes de Leon CF, Arnold SE, Barnes LL, Bienias JL
Neurology 60 (12):1909-15. PubMed PMID: 12821732
Published date: 2003 Jun 24
Terminal decline in cognitive function.
Wilson RS, Beckett LA, Bienias JL, Evans DA, Bennett DA
Neurology 60 (11):1782-7. PubMed PMID: 12796531
Published date: 2003 Jun 10
Gender, cognitive decline, and risk of AD in older persons.
Barnes LL, Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA
Neurology 60 (11):1777-81. PubMed PMID: 12796530
Published date: 2003 Jun 10
Relation of cerebral infarctions to dementia and cognitive function in older persons.
Schneider JA, Wilson RS, Cochran EJ, Bienias JL, Arnold SE, Evans DA, Bennett DA
Neurology 60 (7):1082-8. PubMed PMID: 12682310
Published date: 2003 Apr 8
Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease.
Yang Y, Mufson EJ, Herrup K
The Journal of neuroscience : the official journal of the Society for Neuroscience 23 (7):2557-63. PubMed PMID: 12684440
Published date: 2003 Apr 1
Parkinsonianlike signs and risk of incident Alzheimer disease in older persons.
Wilson RS, Schneider JA, Bienias JL, Evans DA, Bennett DA
Archives of neurology 60 (4):539-44. PubMed PMID: 12707067
Published date: 2003 Apr
Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology.
Ikonomovic MD, Mufson EJ, Wuu J, Cochran EJ, Bennett DA, DeKosky ST
Journal of Alzheimer's disease : JAD 5 (1):39-48. PubMed PMID: 12590165
Published date: 2003 Feb
Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease.
Bennett DA, Wilson RS, Schneider JA, Evans DA, Aggarwal NT, Arnold SE, Cochran EJ, Berry-Kravis E, Bienias JL
Neurology 60 (2):246-52. PubMed PMID: 12552039
Published date: 2003 Jan 28
The apolipoprotein E epsilon 2 allele and decline in episodic memory.
Wilson RS, Bienias JL, Berry-Kravis E, Evans DA, Bennett DA
Journal of neurology, neurosurgery, and psychiatry 73 (6):672-7. PubMed PMID: 12438469
Published date: 2002 Dec
Cerebrospinal fluid shunting for Alzheimer's disease?
Bennett DA, McDermott MP
Neurology 59 (8):1126-7. PubMed PMID: 12391336
Published date: 2002 Oct 22
Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.
Ghoshal N, García-Sierra F, Wuu J, Leurgans S, Bennett DA, Berry RW, Binder LI
Experimental neurology 177 (2):475-93. PubMed PMID: 12429193
Published date: 2002 Oct
Tau conformational changes correspond to impairments of episodic memory in mild cognitive impairment and Alzheimer's disease.
Ghoshal N, García-Sierra F, Wuu J, Leurgans S, Bennett DA, Berry RW, Binder LI
Experimental neurology 177 (2):475-93. PubMed PMID: 12429193
Published date: 2002 Oct
Natural history of mild cognitive impairment in older persons.
Bennett DA, Wilson RS, Schneider JA, Evans DA, Beckett LA, Aggarwal NT, Barnes LL, Fox JH, Bach J
Neurology 59 (2):198-205. PubMed PMID: 12136057
Published date: 2002 Jul 23
The apolipoprotein E epsilon 4 allele and decline in different cognitive systems during a 6-year period.
Wilson RS, Schneider JA, Barnes LL, Beckett LA, Aggarwal NT, Cochran EJ, Berry-Kravis E, Bach J, Fox JH, Evans DA, Bennett DA
Archives of neurology 59 (7):1154-60. PubMed PMID: 12117364
Published date: 2002 Jul
Progression of gait disorder and rigidity and risk of death in older persons.
Wilson RS, Schneider JA, Beckett LA, Evans DA, Bennett DA
Neurology 58 (12):1815-9. PubMed PMID: 12084882
Published date: 2002 Jun 25
Individual differences in rates of change in cognitive abilities of older persons.
Wilson RS, Beckett LA, Barnes LL, Schneider JA, Bach J, Evans DA, Bennett DA
Psychology and aging 17 (2):179-93. PubMed PMID: 12061405
Published date: 2002 Jun
Association between blood pressure and cognitive function in a biracial community population of older persons.
Morris MC, Scherr PA, Hebert LE, Bennett DA, Wilson RS, Glynn RJ, Evans DA
Neuroepidemiology 21 (3):123-30. PubMed PMID: 12006775
Published date: 2002 May-Jun
Participation in cognitively stimulating activities and risk of incident Alzheimer disease.
Wilson RS, Mendes De Leon CF, Barnes LL, Schneider JA, Bienias JL, Evans DA, Bennett DA
JAMA 287 (6):742-8. PubMed PMID: 11851541
Published date: 2002 Feb 13
Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
Mufson EJ, Ma SY, Dills J, Cochran EJ, Leurgans S, Wuu J, Bennett DA, Jaffar S, Gilmor ML, Levey AI, Kordower JH
The Journal of comparative neurology 443 (2):136-53. PubMed PMID: 11793352
Published date: 2002 Feb 4
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment.
DeKosky ST, Ikonomovic MD, Styren SD, Beckett L, Wisniewski S, Bennett DA, Cochran EJ, Kordower JH, Mufson EJ
Annals of neurology 51 (2):145-55. PubMed PMID: 11835370
Published date: 2002 Feb
Parahippocampal tau pathology in healthy aging, mild cognitive impairment, and early Alzheimer's disease.
Mitchell TW, Mufson EJ, Schneider JA, Cochran EJ, Nissanov J, Han LY, Bienias JL, Lee VM, Trojanowski JQ, Bennett DA, Arnold SE
Annals of neurology 51 (2):182-9. PubMed PMID: 11835374
Published date: 2002 Feb
Impaired production priming and intact identification priming in Alzheimer's disease.
Fleischman DA, Monti LA, Dwornik LM, Moro TT, Bennett DA, Gabrieli JD
Journal of the International Neuropsychological Society : JINS 7 (7):785-94. PubMed PMID: 11771621
Published date: 2001 Nov
Annual incidence of Alzheimer disease in the United States projected to the years 2000 through 2050.
Hebert LE, Beckett LA, Scherr PA, Evans DA
Alzheimer disease and associated disorders 15 (4):169-73. PubMed PMID: 11723367
Published date: 2001 Oct-Dec
MRI-derived entorhinal and hippocampal atrophy in incipient and very mild Alzheimer's disease.
Dickerson BC, Goncharova I, Sullivan MP, Forchetti C, Wilson RS, Bennett DA, Beckett LA, deToledo-Morrell L
Neurobiology of aging 22 (5):747-54. PubMed PMID: 11705634
Published date: 2001 Sep-Oct
Down-regulation of trkA mRNA within nucleus basalis neurons in individuals with mild cognitive impairment and Alzheimer's disease.
Chu Y, Cochran EJ, Bennett DA, Mufson EJ, Kordower JH
The Journal of comparative neurology 437 (3):296-307. PubMed PMID: 11494257
Published date: 2001 Aug 27
Type 2 diabetes and cognitive function in community-dwelling elderly women.
Grodstein F, Chen J, Wilson RS, Manson JE
Diabetes care 24 (6):1060-5. PubMed PMID: 11375371
Published date: 2001 Jun
Is the risk of developing Alzheimer's disease greater for women than for men?
Hebert LE, Scherr PA, McCann JJ, Beckett LA, Evans DA
American journal of epidemiology 153 (2):132-6. PubMed PMID: 11159157
Published date: 2001 Jan 15
Galanin: neurobiologic mechanisms and therapeutic potential for Alzheimer's disease.
Counts SE, Perez SE, Kahl U, Bartfai T, Bowser RP, Deecher DC, Mash DC, Crawley JN, Mufson EJ
CNS drug reviews 7 (4):445-70. PubMed PMID: 11830760
Published date: 2001 Winter
Part I. Epidemiology and public health impact of Alzheimer's disease.
Bennett DA
Disease-a-month : DM 46 (10):657-65. PubMed PMID: 11078008
Published date: 2000 Oct
Part II. Clinical diagnosis and course of Alzheimer's disease.
Bennett DA
Disease-a-month : DM 46 (10):666-86. PubMed PMID: 11078009
Published date: 2000 Oct
From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy.
de Toledo-Morrell L, Goncharova I, Dickerson B, Wilson RS, Bennett DA
Annals of the New York Academy of Sciences 911 (6):240-53. PubMed PMID: 10911878
Published date: 2000 Jun
Diabetes and change in cognitive function.
Bennett DA
Archives of internal medicine 160 (2):141-3. PubMed PMID: 10647749
Published date: 2000 Jan 24
Dimensionality of parkinsonian signs in aging and Alzheimer's disease.
Bennett DA, Shannon KM, Beckett LA, Wilson RS
The journals of gerontology. Series A, Biological sciences and medical sciences 54 (4):M191-6. PubMed PMID: 10219010
Published date: 1999 Apr
Word-stem completion priming in healthy aging and Alzheimer's disease: the effects of age, cognitive status, and encoding.
Fleischman DA, Gabrieli JD, Gilley DW, Hauser JD, Lange KL, Dwornik LM, Bennett DA, Wilson RS
Neuropsychology 13 (1):22-30. PubMed PMID: 10067772
Published date: 1999 Jan
Object decision priming in Alzheimer's disease.
Fleischman DA, Gabrieli JD, Reminger SL, Vaidya CJ, Bennett DA
Journal of the International Neuropsychological Society : JINS 4 (5):435-46. PubMed PMID: 9745233
Published date: 1998 Sep
Metric properties of nurses' ratings of parkinsonian signs with a modified Unified Parkinson's Disease Rating Scale.
Bennett DA, Shannon KM, Beckett LA, Goetz CG, Wilson RS
Neurology 49 (6):1580-7. PubMed PMID: 9409350
Published date: 1997 Dec
Around the WORLD backward: an algorithm for scoring the MMSE WORLD item.
Beckett LA, Wilson RS, Bennett DA, Morris MC
Neurology 48 (6):1733-4. PubMed PMID: 9191800
Published date: 1997 Jun
Word-stem completion priming for perceptually and conceptually encoded words in patients with Alzheimer's disease.
Fleischman DA, Gabrieli JD, Rinaldi JA, Reminger SL, Grinnell ER, Lange KL, Shapiro R
Neuropsychologia 35 (1):25-35. PubMed PMID: 8981374
Published date: 1997 Jan
Epidemiology of injury in people with Alzheimer's disease.
Oleske DM, Wilson RS, Bernard BA, Evans DA, Terman EW
Journal of the American Geriatrics Society 43 (7):741-6. PubMed PMID: 7602023
Published date: 1995 Jul
White matter changes: neurobehavioral manifestations of Binswanger's disease and clinical correlates in Alzheimer's disease.
Bennett DA, Gilley DW, Lee S, Cochran EJ
Dementia (Basel, Switzerland) 5 (3-4):148-52. PubMed PMID: 8087170
Published date: 1994 May-Aug
Pathological changes in frontal cortex from biopsy to autopsy in Alzheimer's disease.
Bennett DA, Cochran EJ, Saper CB, Leverenz JB, Gilley DW, Wilson RS
Neurobiology of aging 14 (6):589-96. PubMed PMID: 8295661
Published date: 1993 Nov-Dec