This variable has been replaced by tangsqrt_est_8reg.

Neuronal neurofibrillary tangles are identified by molecularly specific immunohistochemistry (antibodies to abnormally phosphorylated Tau protein, AT8). Cortical density (per mm2) is determined using systematic sampling. Mean of tangle score in 8 regions (4 or more regions are needed to calculate).

8 regions used : tangles_hip - hippocampus : tangles_ec - entorhinal cortex : tangles_mf - midfrontal cortex : tangles_it - inferior temporal : tangles_ag - angular gyrus : tangles_calc - calcarine cortex : tangles_cg - anterior cingulate cortex : tangles_sf - superior frontal cortex

Item level variables are available upon request.