Variable Details

Available Studies

ROS, MAP, MARS, Clinical Core, LATC

Scaled? 

Scaled

Variable Type 

Cross-Sectional

Variable Name 

plaq_d

Categories

Pathology

Diffuse plaque burden
Diffuse plaque summary based on 5 regions

Diffuse plaque burden is determined by microscopic examination of silver-stained slides from 5 regions: midfrontal cortex, midtemporal cortex, inferior parietal cortex, entorhinal cortex, and hippocampus. The count of each region is scaled by dividing by the corresponding standard deviation. The 5 scaled regional measures are then averaged to obtain a summary measure for diffuse plaque burden.

Diffuse plaque pathology counts by region:

RegionVariable
Entorhinal cortexplaq_d_ec
Hippocampus (CA1)plaq_d_hip
Midtemporal cortexplaq_d_mt
Inferior parietal cortexplaq_d_ag
Midfrontal cortexplaq_d_mf
Burden across regionsplaq_d

Notes: Counts may be missing for regions (e.g., due to damage from infarct). If data are present for at least 2 of 5 regions, the summary measure for diffuse plaque burden is computed.

Item level variables are available upon request.

This variable replaces dp.