Variable Details
Available Studies
ROS, MAP, MARS, Clinical Core, LATC
Categories
Pathology
AD neuropathologic change (2 levels)
AD neuropathologic change based on NIA-AA criteria - 2 levels
AD neuropathologic change (2 levels) is the dichotomized version of the National Institute on Aging-Alzheimer's Association criteria for the pathologic diagnosis of Alzheimer's disease. See NIA-AA diagnosis of AD - 4 levels for more information.
The neuropathologist determines the level of AD pathology. Those with intermediate or high likelihood fulfill criteria for having a pathologic diagnosis of AD.
| Value | Coding |
|---|---|
| 1 | AD present by NIA-AA pathology criteria (high or intermediate likelihood) |
| 0 | AD not present by NIA-AA pathology criteria (low likelihood or no AD) |
This is the most up-to-date consensus pathologic diagnosis for AD. This variable replaces "ad_reagan", which was based on NIA-Reagan diagnostic criteria.