Variable Details

Available Studies

ROS, MAP, MARS, Clinical Core, LATC

Scaled? 

Not Scaled

Variable Type 

Cross-Sectional

Variable Name 

ad_reagan

Categories

Pathology

NIA-Reagan diagnosis of AD (dichotomous) - OLD
Presence of AD based on NIA-Reagan diagnosis criteria - dichotomous

This variable is based on NIA-Reagan diagnostic criteria. Please see ad_adnc for the most up-to-date NIA-AA consensus pathologic diagnosis for AD.

This variable is the dichotomized version of the modified NIA-Reagan diagnosis of Alzheimer's disease. The criteria rely on both neurofibrillary tangles (Braak) and neuritic plaques (CERAD). See NIA-Reagan diagnosis of AD - 4 levels for more information.

ValueCoding
1AD present by NIA-Reagan pathology criteria (high or intermediate likelihood)
0AD not present by NIA-Reagan pathology criteria (low likelihood or no AD)