The RADC offers the following set of 84 variables as a standard collection of commonly requested data. Other variables are available through custom requests. Occasionally changes are made to this list--please see summary of changes here.
Label | Category | Longitudinal | Short Description | |
---|---|---|---|---|
1 | apoe_genotype | ApoE and TOMM40 - ApoE | Apolipoprotein E genotype | |
2 | age_first_ad_dx | Clinical Diagnosis - Dementia | Age at cycle where first Alzheimer's dementia diagnosis was given | |
3 | dcfdx | Clinical Diagnosis - Dementia | Longitudinal | Clinical diagnosis of cognitive status (Alzheimer's dementia, other dementia, MCI, or no impairment) |
4 | cogdx | Clinical Diagnosis - Final consensus diagnosis | Clinical consensus diagnosis of cognitive status at time of death | |
5 | r_pd | Clinical Diagnosis - Parkinson's disease | Longitudinal | Diagnosis of Parkinson's disease made by clinician based on clinical review |
6 | r_stroke | Clinical Diagnosis - Stroke | Longitudinal | Diagnosis of stroke made by clinician |
7 | cogn_ep | Cognition - Domains | Longitudinal | Episodic memory domain - Average of 7 tests |
8 | cogn_po | Cognition - Domains | Longitudinal | Visuospatial ability/perceptual orientation domain - Average of 2 tests |
9 | cogn_ps | Cognition - Domains | Longitudinal | Perceptual speed domain - Average of 4 tests |
10 | cogn_se | Cognition - Domains | Longitudinal | Semantic memory domain - Average of 3 tests |
11 | cogn_wo | Cognition - Domains | Longitudinal | Working memory domain - Average of 3 tests |
12 | cogn_global | Cognition - Global cognition | Longitudinal | Global cognitive function - Average of 19 tests |
13 | mem_trbl_tot | Cognition - Self-reported cognitive concerns | Longitudinal | Presence of memory complaints |
14 | cts_estmmse30 | Cognition - Test scores | Longitudinal | |
15 | cts_moca30 | Cognition - Test scores | Montreal Cognitive Assessment | |
16 | phone_cog | Cognition - Test scores | Longitudinal | |
17 | age_bl | Demographics | Age at baseline assessment | |
18 | age_death | Demographics | Age at death | |
19 | died | Demographics | Indicates whether participant died | |
20 | educ | Demographics | Years of education | |
21 | marital_now_bl | Demographics | Marital status at baseline | |
22 | msex | Demographics | Sex | |
23 | race7 | Demographics | Racial group | |
24 | spanish | Demographics | Spanish/Hispanic/Latino origin | |
25 | cesdsum | Depression | Longitudinal | Measure of depressive symptoms (Modified CES-D) |
26 | iadlsum | Disabilities | Longitudinal | Instrumental activities of daily living - Sum of 8 items |
27 | katzsum | Disabilities | Longitudinal | Basic activities of daily living - Sum of 6 items |
28 | rosbsum | Disabilities | Longitudinal | Mobility disability - Sum of 3 items (Rosow-Breslau scale) |
29 | alcohol_g_bl | Lifestyle - Alcohol and tobacco use | Grams of alcohol used per day at baseline | |
30 | ldai_bl | Lifestyle - Alcohol and tobacco use | Self-reported lifetime daily alcohol intake - baseline | |
31 | smoking_bl | Lifestyle - Alcohol and tobacco use | Smoking status at baseline | |
32 | late_life_cogact_freq | Lifestyle - Cognitive activity | Longitudinal | Frequency of participation in cognitively stimulating activity in late life - Average of 7 items |
33 | bmi | Lifestyle - Physical activity and BMI | Longitudinal | Body mass index |
34 | phys5itemsum | Lifestyle - Physical activity and BMI | Longitudinal | Hours of physical activity in late life - Sum of 5 items |
35 | late_life_soc_act | Lifestyle - Social engagement | Longitudinal | Frequency of participation in social activity in late life |
36 | soc_net | Lifestyle - Social engagement | Longitudinal | Size of social network based on the number of children, family, and friends seen at least once a month |
37 | social_isolation | Lifestyle - Social engagement | Longitudinal | Perceived social isolation (loneliness) |
38 | dbp_avg | Medical Conditions - Blood pressure | Longitudinal | Diastolic blood pressure - Average of 3 readings |
39 | hypertension_cum | Medical Conditions - Blood pressure | Longitudinal | Self-reported history of hypertension |
40 | sbp_avg | Medical Conditions - Blood pressure | Longitudinal | Systolic blood pressure - Average of 3 readings |
41 | cancer_bl | Medical Conditions - Cancer | Self-reported history of cancer at baseline | |
42 | diabetes_sr_rx | Medical Conditions - Diabetes | Longitudinal | Diabetes (self-report + Rx) |
43 | bisq_tbi | Medical Conditions - Head injury | Longitudinal | BISQ - Presence of traumatic brain injury |
44 | headinjrloc_bl | Medical Conditions - Head injury | Self-reported history of head injury with loss of consciousness at baseline | |
45 | med_con_sum_bl | Medical Conditions - Summary measures | Self-reported medical condition - baseline | |
46 | thyroid_bl | Medical Conditions - Thyroid | Self-reported history of thyroid disease at baseline | |
47 | claudication_cum | Medical Conditions - Vascular | Longitudinal | Self-reported history of claudication |
48 | heart_cum | Medical Conditions - Vascular | Longitudinal | Self-reported history of heart conditions |
49 | stroke_cum | Medical Conditions - Vascular | Longitudinal | History of stroke based on clinician review |
50 | vasc_3dis_sum | Medical Conditions - Vascular | Longitudinal | Cumulative vascular disease burden - Average of 3 items |
51 | vasc_risks_sum | Medical Conditions - Vascular | Longitudinal | Cumulative vascular disease risk factors - Average of 3 items |
52 | motor_dexterity | Motor and Gait - Motor function measures | Longitudinal | Motor function partial composite: Dexterity |
53 | motor_gait | Motor and Gait - Motor function measures | Longitudinal | Motor function partial composite: Gait |
54 | motor_handstreng | Motor and Gait - Motor function measures | Longitudinal | Motor function partial composite: Hand strength |
55 | motor10 | Motor and Gait - Motor function measures | Longitudinal | Motor function composite - Average of 10 tests |
56 | gaitsc | Motor and Gait - UPDRS | Longitudinal | Parkinsonian signs domain: Gait |
57 | a_score_st4 | Pathology - Alzheimer's disease | Amyloid beta plaque score based on Thal plaque phase | |
58 | ad_adnc | Pathology - Alzheimer's disease | AD neuropathologic change based on NIA-AA criteria - 2 levels | |
59 | adnc | Pathology - Alzheimer's disease | AD neuropathologic change based on NIA-AA criteria - 4 levels | |
60 | b_score | Pathology - Alzheimer's disease | NFT stage (4 levels), derived from Braak Stage | |
61 | braaksc | Pathology - Alzheimer's disease | Semiquantitative measure of neurofibrillary tangles | |
62 | c_score | Pathology - Alzheimer's disease | Neuritic plaque score (4 levels), derived from CERAD | |
63 | ceradsc | Pathology - Alzheimer's disease | Semiquantitative measure of neuritic plaques | |
64 | gpath | Pathology - Alzheimer's disease | Global burden of AD pathology based on 5 regions | |
65 | pmi | Pathology - Autopsy - General | Time interval in hours from time of death to autopsy | |
66 | amylsqrt_est_8reg | Pathology - Beta-Amyloid | Amyloid density after square root transformation | |
67 | hip_scl_yn_mid | Pathology - Hippocampal sclerosis | Presence of hippocampal sclerosis in mid-hippocampus | |
68 | dlbdx | Pathology - Lewy body/PD | Pathologic diagnosis of Lewy body diseases - 4 stages | |
69 | tangsqrt_est_8reg | Pathology - Neurofibrillary tangles | Tangle density after square root transformation | |
70 | tdp_st4 | Pathology - TDP-43 | TDP-43 pathology - 4 stages (8 regions) | |
71 | arteriol_scler | Pathology - Vascular - General measures | Arteriolosclerosis - 4 stages | |
72 | caa_4gp | Pathology - Vascular - General measures | Cerebral amyloid angiopathy - 4 stages | |
73 | cvda_4gp2 | Pathology - Vascular - General measures | Cerebral Atherosclerosis Rating - 4 levels (None - severe) | |
74 | ci_num2_gct | Pathology - Vascular - Infarcts (Presence of) | Cerebral Infarctions - Binary - Gross-Chronic-Any Location | |
75 | ci_num2_mct | Pathology - Vascular - Infarcts (Presence of) | Cerebral Infarctions - Binary - Micro-Chronic-Any Location | |
76 | early_hh_ses | SES and Cognitive Resources - SES | Early life socioeconomic status - Average of 3 items | |
77 | income_bl | SES and Cognitive Resources - SES | Income level at baseline (10-level) | |
78 | vision | Vision | Longitudinal | Near-vision acuity based on Rosenbaum Pocket Vision Screener |
79 | purpose_total | Well-being | Longitudinal | Sense of purpose in life |
80 | satis1 | Well-being | Longitudinal | Overall satisfaction with life rating - 1 question |
81 | satis2 | Well-being | Longitudinal | Overall happiness rating - 1 question |
82 | satisfaction | Well-being | Longitudinal | Satisfaction With Life Scale - Average of 5 items |
83 | timehoriz | Well-being | Longitudinal | Perceived time horizon - Average of 6 items |
84 | wellbeing | Well-being - Well-being scale | Longitudinal | Overall well-being - Average of 18 items |