Requests for biospecimens will be reviewed by Rush
Alzheimer's Disease Center's Biospecimen Distribution Committee.
Review criteria include the scientific merit of the proposal,
evaluation of plans to exploit the full potential of the
resources, ability of the investigators to carry out the proposed
work, federal or foundation funding source, and amount and
availability of biospecimens.
Prospective recipients of specimens
in limited supply are strongly encouraged to work closely and
collaboratively with a Rush Alzheimer's Disease Center
investigator in order to take maximal advantage of limited
Biospecimens will not be distributed without a signed Rush
Alzheimer's Disease Center Biologic
Material Transfer Agreement and executed Letter of Agreement. The
agreement was developed by the Rush Alzheimer's Disease Center in
consultation with our External Advisors, NIA staff, and the Rush
Office of Legal Affairs. Some investigators have data collection
in multiple laboratories for the same study; under these
circumstances the BMTA must be signed by the co-investigator from
each laboratory. Tissue will be distributed from the Rush Alzheimer's Disease Center only; the
Letter of Agreement prohibits third distribution of materials or
data. Please indicate the additional investigator(s) who will
need to sign the agreement by checking the "BMTA required?" box by each name in the request form.
Additional application information
Go to Specimen Request
Limited Data Set
The data sets provided by the RADC are all de-identified and contain no protected health information.
We refer to them as Limited because our data has been shared with many researchers outside of the RADC and some of our data is available on public access sites (including genomic data).
The possible combination of already distributed and available data could lead to our participants being identified.
We seek the best protection for our research participants. A signed Data Use Agreement is required for distribution and use.
See the Data Use Agreement and HIPAA privacy rule for more information.
Go to Limited Data Request
New Study Recruitment
Researchers may be able to recruit from the subset of RADC's participant pool that has consented to contact regarding
new studies. Please see the detailed instructions
for requesting approval.
Create New Study Recruitment Request
BRAIN-ICU-2 COVID-19 Specimens
BRAIN-ICU-2 is a collaboration between the Rush Alzheimer's Disease Center (RADC) and Vanderbilt University Medical Center (VUMC).
Following the COVID-19 outbreak, a supplemental grant was obtained to apply the BRAIN-ICU-2 protocols to individuals admitted at Vanderbilt University Medical Center for treatment. As of Dec 2020, 19 participants with
COVID-19 have have donated brain and brainstem tissue for research and sharing through the RADC Data and Biospecimen Repository. The tissue is all fixed in formalin; no frozen tissue is available.
Go to BRAIN-ICU-2 COVID-19 Specimen Request
Pathology, Alzheimer's and Related Dementias Study
Go to PARDoS Specimen Request