BRAIN-ICU-2 Biospecimen Resource Request

If you are interested in using data from BRAIN-ICU-2, please review the Data and Resource Sharing Policy as well as the Data and Biologic Material Transfer Agreement before submitting a request for data or specimens. You will need to create an account (with username and password) to use the request system.

Brain-ICU-2 data is not yet available.
Create BRAIN-ICU-2 Biospecimen Request

COVID-19 Supplement Biospecimens

Following the COVID-19 outbreak, a supplemental grant was obtained to apply the BRAIN-ICU-2 protocols to individuals admitted at Vanderbilt University Medical Center for treatment. As of Dec 2020, 19 participants with COVID-19 have have donated brain and brainstem tissue for research and sharing through the RADC Data and Biospecimen Repository. The tissue is all fixed in formalin; no frozen tissue is available.

Available Data

Clinical and demographic data collected through study participation is available.

Create BRAIN-ICU-2 COVID-19 Biospecimen Request

Application Process

Enter Request

The application process is implemented through a web-based form. As each page is completed the form is saved. Any page can be updated at any time before the form is submitted.

  1. Investigator Intent for Intellectual Property
  2. Principal Investigator or Project Leader
  3. Co-Investigators
  4. Study Information
    • Title
    • For funded projects - funding source, agency, grant number
    • For preliminary projects - preliminary funding source, planned submission agency, due date, allowable costs
  5. Specimen
    • Specimen requested
    • Procedure to be done on specimen
  6. Experimental Plan
    • Brief analytic plan
  7. Other Information
    • Additional information on data requested for analyses
    • FedEx number
    • Comment
  8. Upload Documents
  9. Review and Submit

Submit the Request

From this point on, the web system will direct the next steps. The system will send updates to email address of primary investigator. You may want to consider using the address of another staff member who will be in charge of tracking progress.


Committee - Your request will be reviewed by the RADC Resource Distribution Committee

3 outcomes (all notified to applicant via email)

  1. Rejected - explanation will be given.
  2. Returned for revisions prior to approval.
  3. Approved

The next three steps can be occurring simultaneously following approval.

  1. Obtain signatures on the appropriate Material Transfer Agreement (MTA). The correct agreement depends on whether your institution is a signatory to the Uniform Biological Materials Transfer Agreement. For more information and actual agreements, see the transfer agreements forms page. You should start immediately after request approval as this step can sometimes take as much as a few months to work through.
  2. Work on general timeline of delivery of data with Resource Sharing Coordinator, Greg Klein (
  3. Refine data needs with Resource Sharing Coordinator.

After agreement is fully executed and saved on file at Rush, you will receive your data.

The Data and Specimen Sharing Agreements with the National Institutes of Health require Rush investigators to track the distribution of all data and specimens, including the recipients' grant numbers and funding.


If you have any questions about any of the below items, please contact RADC Data Sharing Coordinator Greg Klein at

Brain Processing Procedure