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Home
Documentation
Variables
Pathology
gfap_frac_sqrt_hip
Variable Details
Pathology
gfap_frac_sqrt_hip
Alzheimer's disease
A score
Braak stage
B score
CERAD score
C score
AD neuropathologic change (4 levels)
AD neuropathologic change (2 levels)
NIA-Reagan diagnosis of AD - OLD
NIA-Reagan diagnosis of AD (dichotomous) - OLD
Global AD pathology burden - OLD
Global neuritic plaque-tangle burden
Beta-Amyloid
Diffuse plaque burden
Neuritic plaque burden
Amyloid density (8 regions)
Amyloid - OLD
Neurofibrillary tangles
Neurofibrillary tangles (NFT)
Tangle density (8 regions)
PHF Tau Tangle Density - OLD
Lewy body/PD
Lewy body disease
Lewy bodies (7 regions)
Vascular - Infarcts (Presence of)
Presence of one or more gross chronic infarcts
Presence of one or more chronic microinfarcts
Presence of one or more chronic infarcts
Vascular - General measures
Cerebral atherosclerosis
Cerebral amyloid angiopathy
Arteriolosclerosis
Hippocampal sclerosis
Presence of hippocampal sclerosis
TDP-43
TDP-43 stage
Autopsy - General
Post-mortem interval
Scaled?
Not Scaled
Variable Type
Cross-Sectional
Variable Name
gfap_frac_sqrt_hip
Categories
Pathology
gfap_frac_sqrt_hip
Publications
Agrawal S, Yu L, Leurgans SE, Li J, Kapasi A, Agarwal P, Dage JL, Barnes LL, Bennett DA, Boyle P, Schneider JA.
Hippocampal GFAP in aging: Associations with AD and LATE-NC pathologies and cognitive decline in older adults.
Alzheimer's & dementia : the journal of the Alzheimer's Association. 2026 Jun; 22 (6):e71613. PubMed PMID: 42309988; PubMedCentral PMCID: PMC13275333
